Orthologs, Diseases, and Interactions

Orthologs, Diseases, and Interactions

Norie de la Cruz

Moving through and across the data

Gene

Orthologs

Disease

Interaction

Ontology

Disease Search for “cardio”

Genes and Diseases

To and from genes

Gene to interactions ….

Interactions Summary for gene

Interaction Report

To and from genes

Gene to Other orthologs and diseases ….

List of orthologs for gene

Orthology Report

List of diseases for gene

Searching Multiple Ontologies

Multiple ontology search results

Ontology browser upgrade

The fun goes on ….

• Work with OMIM to link back to WB

• Addition of OMIM data to AceDB

• Links to and from Reactome and HapMap projects

Thank you!

End

Succeeding slides are extra !!!

Reports

• Back and forth links between ontologies and associated objects

• Back and forth links to related terms in other ontologies

• Browser with links to WormMart

Orthology and Disease

• Search functionalities

• Interlinking between pages

Disease Report

Disease Search

Acknowledgements

• Todd Harris• Lincoln Stein• Dev Group: Sheldon Mckay, Will Spooner, Zheng

Zha• WormBase staff