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Experiences with developing a commercial solution to Johne’s control in the UK Peter Orpin* 1, 2 , Richard J. Sibley3 1 Park Vet Group, Whetstone, Leicestershire, 2 Special Lecturer, Nottingham University, Nottingham, United Kingdom, 3 Westridge Veterinary Group, Witheridge, Tiverton [email protected]
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Orpin Buiatrics Johnes 2016

Jan 23, 2017

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Page 1: Orpin Buiatrics Johnes 2016

ExperienceswithdevelopingacommercialsolutiontoJohne’scontrolintheUK

PeterOrpin*1,2,RichardJ.Sibley31ParkVetGroup,Whetstone,Leicestershire,2SpecialLecturer,

NottinghamUniversity,Nottingham,UnitedKingdom,3Westridge VeterinaryGroup,Witheridge,Tiverton

[email protected]

Page 2: Orpin Buiatrics Johnes 2016

RisingincidenceinUK2000-2010Riskofspreadwithinandbetweenherdsincreasedwithconsolidation,expansionandintensificationofherds

Page 3: Orpin Buiatrics Johnes 2016

IncreasingunderstandingofeconomiceffectsinpreclinicalphaseIncreasingcauseofcullinglosses(directandindirect)

Page 4: Orpin Buiatrics Johnes 2016

Pyramidofinfectionandshedding

Myhealthyherdcopyright08/08/2016

Clinicalcowsarethedistraction!

Economiclossesappearhere

Page 5: Orpin Buiatrics Johnes 2016

EconomicconsequencesofJohne’s

Direct

Indirect

Consequentiallosses

Prematureculling,milklosses,treatments

Increasedriskofudderdisease

Retentionofhighriskcowswithlowereconomicperformance

Increasedriskoflowerfertility,furtheremergencyculling,udderdiseaseandlameness

Page 6: Orpin Buiatrics Johnes 2016

TheeconomiceffectsofJohne’sdiseaseDeathornovaluecullMilkproductionlossSlaughtervaluelossDiseaseassociationsPrematurecullTreatmentcosts

EmergencyorforcedcullMilkproductionlossSlaughtervaluelossDiseaseassociationsPrematurecull

PrematureplannedcullMilkproductionlossDiseaseassociationsPrematurecull

Cullcost£3406/case

Cullcost£2408/case

Cullcost£1304/case

Page 7: Orpin Buiatrics Johnes 2016

DriversfortheJohne’sEngagementPlan

• FurtherimproveHealthandWelfare• Economicbenefitstotheproducers• ProvideframeworkforprocessorsandfarmerswishingtoprogressfurtherwithJohne’scontrolfortradingpurposes

• Demonstratetoconsumersthatanypotentialzoonoticthreatisbeinghandledresponsibly

Page 8: Orpin Buiatrics Johnes 2016

Johne’sActionGroupandConferences

• 2010DairyUKheldanindustryconferenceonJohne’sdisease

• EstablishedJohne’sActionGrouptohelpco-ordinateJohne’scontrolinGBDairyherd

• Keymembers- Vets,processors,milkrecordingorganisations,farmersunions

Page 9: Orpin Buiatrics Johnes 2016

08/08/2016 Myhealthyherdcopyright

LongTermObjectivesoftheJohne’sManagementPlan

“TocontrolandthenreducetheincidenceofJohne’sdiseaseindairycattlewiththelongtermobjectiveofeliminatingthediseaseifitbecomestechnicallyandeconomicallyfeasibletodoso”.

Page 10: Orpin Buiatrics Johnes 2016

Johne’sEngagementPlan

• Aimwastoengageall dairyfarmersineffectiveJohne’smanagementthatsuitedtheirfarm

• PredictandPreventJohne’sdisease- protecttheuninfectedherdsaswellasmanagetheinfectedherds

• Keypriority- “Removebarrierstoengagementandmotivatevetsandfarmers totakepositiveaction”

Orpin.P.G,SibleyR.J..PredictandPreventvsTestandTreat.(2014)VeterinaryRecord 174:403-405doi:10.1136/vr.g2749

Page 11: Orpin Buiatrics Johnes 2016

SorrytohearabouttheJohne’s

diagnosisNotaproblem,I’veculledher

already

“Johne’scontrolismorethanjustatestandcullprogram”

Page 12: Orpin Buiatrics Johnes 2016

Thekeyobjective:BreakingtheJohne’sCycle

Cow infects calf through milk, faeces or in utero

Calf becomes infected

Heifer enters herd as apparently healthy animal and gradually develops disease

Myhealthyherdcopyright08/08/2016

Page 13: Orpin Buiatrics Johnes 2016

UKJohne’sEngagementProgram

Education

Surveillance

RiskAssessment

Strategiccontrols

Myhealthyherdcopyright08/08/2016

Page 14: Orpin Buiatrics Johnes 2016

RegionalControlSchemes

• TwomajorfundedregionalJDcontrolschemes2011-2014

• HealthyLivestock(SouthWest)• NorthWestRegionalDevelopment

• DeliveredusingMyhealthyherdascentraldatabase

Page 15: Orpin Buiatrics Johnes 2016

Johne’sActionGroup- Keysuccesses

• CommonuseofIDEXXELISAforallmajormilkrecordingorganisations

• EstablishedacceptanceofmilkELISAanduseofthetargeted30cowscreenasatoolforinitialsurveillance

• Promotedengagementbetweencommercialpartners/processors

Page 16: Orpin Buiatrics Johnes 2016

Johne’sActionGroup- Keysuccesses

• Retainedfocusonengagingfarmers ratherthansurveillance

• Avoidedclassificationofherdsbystatusaslikelytodisengageinfectedfarmers

• Educationofvetsandfarmerswithcommonmessages

• Engageallherdsnotjustinfected-protecttheuninfected

Avoidingthe“Focusontheurgent”

ClinicalCases Testpositivecows

Page 17: Orpin Buiatrics Johnes 2016

RiskAssessmentsandstrategiccontrols• Encouragedastrategicapproach anddevelopedandendorsed6Johne’scontrolstrategies

• Ensuredriskassessmentandmanagementcentraltocontrol

• Farmspecificsolutionsbasedonaspirations,resources,prevalenceandrisks

04/07/2016 Myhealthyherdcopyright

Page 18: Orpin Buiatrics Johnes 2016

FarmerandVetFriendlyapproaches

• OpenaccesstoJohne’sActionGroupbyparticipatingprocessors

• Effectivecommunicationbetweenstakeholders

• Avoidingonerousrules,legalities,testingburdens

• Facilitatevet- farmerengagement

Page 19: Orpin Buiatrics Johnes 2016

First5yearsJDengagementprogram

• 300+meetingsto2500+farmersviamajormilkprocessors

• Over2200farmerscompletedriskassessmentsusingMyhealthyherd

• 350+vetseducatedinprinciplesofcontrol

• Annual/BiennialJohne’sconferencestoengageindustry

Page 20: Orpin Buiatrics Johnes 2016

NationalJohne’sManagementPlan2015

• Strengthentheengagementprocess

• DevelopmentofActionJohne’swebsite

• Recruitmentofdeliveryteamtaskedtohelpcoordinatemessagesandactivities

• Developtechnicalmanual

Page 21: Orpin Buiatrics Johnes 2016

NationalJohne’sManagementPlan- Phase1

• Developedin2015withspecifictargets

• 77%ofGBmilksupplysigneduptotheprogram

• CollationofresultsofengagementbyOctober2016

Page 22: Orpin Buiatrics Johnes 2016

Collaborativeengagement

Page 23: Orpin Buiatrics Johnes 2016

NationalJohne’sManagementPlanobjectivesPhase1(2010-2015)

Targets:• Farmerstodeterminetheirriskandstatus

• PutinplaceinconsultationwiththeirvetoneofthesixstrategiesdevelopedbytheActionGrouponJohne’sinconsultationwiththeirvet

LowPrevalenceLowerrisk

HighprevalenceHigherRisk

BiosecurityProtectandMonitor

ImprovedFarmManagement

IMFandsingleTest

RiskBasedControlandQuarterlymilktest

BreedtoTerminalSire

FirebreakVaccination

ImprovedFarmManagementandTestandCull

Myhealthyherdcopyright04/07/2016

Page 24: Orpin Buiatrics Johnes 2016

NJMP-Phase2(2016+)

• BritishCattleVetAssociationdevelopedwebinarandonlineassessment tocreateagroupofapprovedtrainedvets

• Usethisgrouptomotivate,engageandensurerobustnessofplans

Page 25: Orpin Buiatrics Johnes 2016

NJMPPhase2ObjectivesandPlans

• Consultationwithindustry withplanforveterinarysignoffofrobustveterinaryledcontrolplanbyBCVAtrainedvet

• Crediblevet/farmerinteractioncreatingarobustprotectionandcontrolplan

Page 26: Orpin Buiatrics Johnes 2016

NJMPPhase2-Draftproposals• Developanagreedtimescaleforveterinarysignoffofplans

• Vetsandfarmersprovidedchoicesastowhattoolsandapproachestheyuse

• Robustmanagementplansapplied,farmerpaysforplan,processorencouragescompliance,NJMPprovidesstructure

2017• January2017• Vetreview risks,controlstrategy,signoff

2018• Annual Review• Review ofrisks/robustness/progress

2019• AnnualReview• Reviewofrisks/robustness/progress

Page 27: Orpin Buiatrics Johnes 2016

NationalJohne’sManagementPlan(NJMP)EngagementTimeline

NJMPPhase2– 2016- January2017+

Robustness+Compliance Trainedvets+signoffofplan

NJMPPhase1- 2015-October2016

RisksandStatus 6ControlStrategies

Johne’s Engagement2010-2014

Education RiskandStatus

Page 28: Orpin Buiatrics Johnes 2016

Wherewewanttoendup?

• Farmerandindustrycommerciallydrivensolutions• Drivers forcontinuedengagement• Robustcontroldrivingdownprevalenceininfectedherds• Effectiveprotectionforlowprevalenceherds• Provideplatformofdecreasingprevalenceifamorestructuredprogramisrequiredinthefuture

Page 29: Orpin Buiatrics Johnes 2016

References

www.myhealthyherd.comwww.actionjohnes.org

• OrpinP.G,SibleyR.J,Komorowski E(2012).AvoluntaryJohne'sengagementprogrammeinUKdairyherds3rd ParaTB Forum

• OrpinP.G,SibleyR.J.(2014)AReviewonProgresswithJohne'sEngagementPrograminUKDairyHerds.4th ParaTB forum

• Sibley.R.J,OrpinP.G(2016)TheNationalJohnes ManagementPlan:anationalprogrammeforthemanagementofparatuberculosis intheUKdairyherd.5th ParaTB Forum

Page 30: Orpin Buiatrics Johnes 2016

QuestionsQuestions