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Origins of Modern Origins of Modern Genetics Genetics Jean Baptiste Lamarck (French, Jean Baptiste Lamarck (French, early 19 early 19 th th c.): “The Inheritance of c.): “The Inheritance of Acquired Characteristics” Acquired Characteristics” Charles Darwin (English, 1859): Charles Darwin (English, 1859): Species can change through the Species can change through the process of natural selection process of natural selection Gregor Mendel (Austrian, 1865): Gregor Mendel (Austrian, 1865): Founder of modern genetics; Founder of modern genetics; Experimental discovery of Experimental discovery of inheritance of traits from one inheritance of traits from one generation to the next; genes as generation to the next; genes as material foundation of heredity material foundation of heredity
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Origins of Modern Genetics ► Jean Baptiste Lamarck (French, early 19 th c.): “The Inheritance of Acquired Characteristics” ► Charles Darwin (English, 1859):

Dec 22, 2015

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Page 1: Origins of Modern Genetics ► Jean Baptiste Lamarck (French, early 19 th c.): “The Inheritance of Acquired Characteristics” ► Charles Darwin (English, 1859):

Origins of Modern GeneticsOrigins of Modern Genetics► Jean Baptiste Lamarck (French, early Jean Baptiste Lamarck (French, early

1919thth c.): “The Inheritance of Acquired c.): “The Inheritance of Acquired Characteristics” Characteristics”

►Charles Darwin (English, 1859): Species Charles Darwin (English, 1859): Species can change through the process of can change through the process of natural selection natural selection

►Gregor Mendel (Austrian, 1865): Gregor Mendel (Austrian, 1865): Founder of modern genetics; Founder of modern genetics; Experimental discovery of inheritance of Experimental discovery of inheritance of traits from one generation to the next; traits from one generation to the next; genes as material foundation of genes as material foundation of heredityheredity

Page 2: Origins of Modern Genetics ► Jean Baptiste Lamarck (French, early 19 th c.): “The Inheritance of Acquired Characteristics” ► Charles Darwin (English, 1859):

Jean B. Lamarck (1744-1829)Jean B. Lamarck (1744-1829)

Page 3: Origins of Modern Genetics ► Jean Baptiste Lamarck (French, early 19 th c.): “The Inheritance of Acquired Characteristics” ► Charles Darwin (English, 1859):

Charles Darwin (1809-1882)Charles Darwin (1809-1882)

Page 4: Origins of Modern Genetics ► Jean Baptiste Lamarck (French, early 19 th c.): “The Inheritance of Acquired Characteristics” ► Charles Darwin (English, 1859):

Gregor Mendel (1822-1884)Gregor Mendel (1822-1884)

Page 5: Origins of Modern Genetics ► Jean Baptiste Lamarck (French, early 19 th c.): “The Inheritance of Acquired Characteristics” ► Charles Darwin (English, 1859):

Modern GeneticsModern Genetics

►Thomas Morgan (1866-1945): Located Thomas Morgan (1866-1945): Located genes at chromosomes and developed genes at chromosomes and developed modern genetics through experiments modern genetics through experiments on on DrosophilaDrosophila—fruit flies—fruit flies

►Oswald Avery (1877-1955) and Oswald Avery (1877-1955) and colleagues: Discovered in 1944 that colleagues: Discovered in 1944 that DNA was the molecule that contained DNA was the molecule that contained genetic informationgenetic information

Page 6: Origins of Modern Genetics ► Jean Baptiste Lamarck (French, early 19 th c.): “The Inheritance of Acquired Characteristics” ► Charles Darwin (English, 1859):

Thomas Morgan (1866-1945)Thomas Morgan (1866-1945)

Page 7: Origins of Modern Genetics ► Jean Baptiste Lamarck (French, early 19 th c.): “The Inheritance of Acquired Characteristics” ► Charles Darwin (English, 1859):

Oswald Avery (1877-1955)Oswald Avery (1877-1955)

Page 8: Origins of Modern Genetics ► Jean Baptiste Lamarck (French, early 19 th c.): “The Inheritance of Acquired Characteristics” ► Charles Darwin (English, 1859):

Watson and CrickWatson and Crick

► James Watson (1928-) and Francis Crick James Watson (1928-) and Francis Crick (1916-2004): “Cracked” the molecular (1916-2004): “Cracked” the molecular structure of DNA and explained how the structure of DNA and explained how the genetic codes were transferred from one genetic codes were transferred from one generation to another.generation to another.

►Maurice Wilkins (1916-2004) and Maurice Wilkins (1916-2004) and Rosalind Franklin (1920-1958): made the Rosalind Franklin (1920-1958): made the crucial contributions to Watson and Crick crucial contributions to Watson and Crick with their crystallography of DNAwith their crystallography of DNA

Page 9: Origins of Modern Genetics ► Jean Baptiste Lamarck (French, early 19 th c.): “The Inheritance of Acquired Characteristics” ► Charles Darwin (English, 1859):

James WatsonJames Watson

Page 10: Origins of Modern Genetics ► Jean Baptiste Lamarck (French, early 19 th c.): “The Inheritance of Acquired Characteristics” ► Charles Darwin (English, 1859):

Francis CrickFrancis Crick

Page 11: Origins of Modern Genetics ► Jean Baptiste Lamarck (French, early 19 th c.): “The Inheritance of Acquired Characteristics” ► Charles Darwin (English, 1859):

Rosalind FranklinRosalind Franklin

Page 12: Origins of Modern Genetics ► Jean Baptiste Lamarck (French, early 19 th c.): “The Inheritance of Acquired Characteristics” ► Charles Darwin (English, 1859):

Maurice WilkinsMaurice Wilkins

Page 13: Origins of Modern Genetics ► Jean Baptiste Lamarck (French, early 19 th c.): “The Inheritance of Acquired Characteristics” ► Charles Darwin (English, 1859):

Issues to ConsiderIssues to Consider

►Modern science as interdisciplinaryModern science as interdisciplinary►Biology and physicsBiology and physics► Importance of being at a center of Importance of being at a center of

scientific communicationscientific communication►Styles of scientific researchStyles of scientific research►Gender and scienceGender and science