organic solvent H2OH2O lipids everything else lipids everything else = = "nonhydrolyzable lipids"
Jan 01, 2016
Welcome message from author
This document is posted to help you gain knowledge. Please leave a comment to let me know what you think about it! Share it to your friends and learn new things together.
Transcript
organic solvent
H2O
lipids
everything else
lipids
everything else
HO
H
H
H
cholesterol
pinene
O
OH
HO
O
NN
H2N
N N
adenosine triphosphate (ATP)
PO
O O
PO
O
O
POH
O O
O
O
OH
HO
OHHO
H
glucose
Na Cl
all salts
=O
OO
O
ON
H3C
CH3
CH2
=O
OH
arachidonic acid
"nonhydrolyzable lipids""nonhydrolyzable lipids"
lipids
everything else
Na Cl
all salts O
OH
HO
O
NN
H2N
N N
adenosine triphosphate (ATP)
PO
O O
PO
O
O
POH
O O
O
O
OH
HO
OHHO
H
glucose
=
=O
OO
O
ON
H3C
CH3
CH2
"hydrolyzable lipids""hydrolyzable lipids"
O
O
O
O
O
O
"hydrolyzable lipids""hydrolyzable lipids"
O
O
Na
O
ONa
O
O
Na
O
O
O
H
H
H
+
soapsoap glycerolglycerol
O
O
O
O
O
O
triglyceridetriglyceride
Na OH
"Home made" soap"Home made" soap
1. Na OH
soap soap solutionsolution
2. Na Cl
lyelye
home home made lye made lye soapsoap
saltsalt
Some functions of hydrolyzable lipids in biologySome functions of hydrolyzable lipids in biology
O
O
O
O
O
O
OO22
triglyceridetriglyceride
O
O
leaf coatingsleaf coatingsbees bees waxwax
Some functions of hydrolyzable lipids in biologySome functions of hydrolyzable lipids in biology
waxeswaxes
HO
O
fatty acidsfatty acids
linoleoic acid
HO
O
OH
O
omega-3-omega-3-fatty acidsfatty acids
HO
O
fatty acids propertiesfatty acids properties
linoleoic acid
melting pointmelting point
O
OH
stearic acid
oleic acid
HO
O
-5 °C
13 °C
70 °C
fatty acids propertiesfatty acids properties
stearic acid
mp = 70 °C
fatty acids propertiesfatty acids properties
mp = 13 °Coleic acid
fatty acids propertiesfatty acids properties
mp = -5 °C
fatty acids propertiesfatty acids properties
melting pointmelting point
-5 °C
13 °C
70 °C
fatty acids propertiesfatty acids properties
fatty acids propertiesfatty acids properties
O
O
O
O
O
O
O
O
O
O
O
O
H-Hcatalyst
H-Hcatalyst
liquidliquid
solidsolid
fatty acids fatty acids prostaglandinsprostaglandins
arachidonic acid
OH
O
O2H
CO2HO
O
H
H
PGG2
OH
CO2H
H
H
O
HO
Prostaglandin E2
O2
aspirin and aspirin and ibuprofen ibuprofen inhibit this inhibit this stepstep
SteroidsSteroidsC C
H
H
H
O
OH
OP
O
OO
P
O
OO
squalene
SteroidsSteroids
squalene
SteroidsSteroids
HO
H
H
H
O2
SteroidsSteroids
O
O
H
H
H
progesterone
O
OH
H
H
H
testosterone
HO
OH
H
H
H
estradiolO
O OH
OHHO
H
H
H
cortisol
R
HO
H
H
H
Cholesterol and Cardiovascular DiseaseCholesterol and Cardiovascular Disease
liverliver
R
HO
H
H
H
cholesterolcholesterol
LDLLDL
HDLHDL
R
HO
H
H
H
cholesterolcholesterol
Structure of LDL
Hydrophobic CoreHydrophobic Core of Triglyceride of Triglyceride and Cholesteryl and Cholesteryl EstersEsters
apoBapoB
Surface Surface Monolayer of Monolayer of Phospholipids Phospholipids and Free and Free CholesterolCholesterol
Structure of HDL
Rye KA et al. Atherosclerosis 1999;145:227-238.
Hydrophobic Core
of Triglyceride and Cholesteryl
Esters
apoA-II
Surface Monolayer of Phospholipids
and Free CholesterolapoA-I
Cholesterol and Cardiovascular DiseaseCholesterol and Cardiovascular Disease
liverliver
R
HO
H
H
H
cholesterolcholesterol
LDLLDL
HDLHDL
R
HO
H
H
H
cholesterolcholesterol
XX
Cholesterol and Cardiovascular DiseaseCholesterol and Cardiovascular Disease
Steroid Steroid biosynthesisbiosynthesis C C
H
H
H
O
OHO
P
O
OO
P
O
OO
squalene
HO
H
H
H
O
O
O
HOH
O
H3C
H
H
CH3
H
lovastatinlovastatin
Related Documents
