on Biological Engineering Computing

Jorge Henriques • Nuno Neves •

Paulo de Carvalho

Editors

XV Mediterranean Conference

on Medical and BiologicalEngineering and Computing -

MEDICON 2019

Proceedings of MEDICON 2019,

September 26-28, 2019, Coimbra, Portugal

Set 1

^jy Springer

Contents

Regular Sessions: Biomedical Signal Processing

Using Eye Tracking to Analyze Surgeons' Cognitive Workload

During an Advanced Laparoscopic Procedure 3

Juan Francisco Ortega-Moran, J. Bias Pagador, Vicente Luis-del-Campo,

Juan Carlos Gomez-Bianco, and Francisco M. Sanchez-Margallo

Application of Multivariate Spectral F Test for Somatosensory

Evoked Response Detection 13

Karina Miranda Boson, Antonio Mauricio Ferreira Leite Miranda de Sa,

and Danilo Barbosa Melges

Spatial Cross-Correlation to Determine Atrial Fibrillation

Recurrence After Ablation 22

Raquel Cervigon, Julian Perez-Villacastin, and Javier Moreno

Development of a Computer Simulator of the Visual N2

Event-Related Potential Component for the Studyof Cognitive Processes 29

Francesca Marturano, Sabrina Brigadoi, Mattia Doro, Roberto Dell'Acqua,and Giovanni Sparacino

Automatic Segmentation of Ultrasonic Vocalizations in Rodents 37

Diogo Pessoa, Lorena Petrella, Miguel Castelo-Branco, and Cesar Teixeira

PCG-Decompositor: A New Method for Fetal Phonocardiogram

Filtering Based on Wavelet Transform Multi-level Decomposition 47

Annachiara Strazza, Agnese Sbrollini, Marica Olivastrelli,

Agnese Piersanti, Selene Tomassini, Ilaria Marcantoni, Micaela Morettini,

Sandro Fioretti, and Laura Burattini

xxi

xxii Contents

Muscular Co-contraction Detection: A Wavelet

Coherence Approach 54

Annachiara Strazza, Federica Verdini, Andrea Tigrini, Stefano Cardarelli,

Alessandro Mengarelli, Sandro Fioretti, and Francesco Di Nardo

Calculation of Breath-by-Breath Oxygen Uptake in Asthmatic

Patients by the "Independent Breath" Algorithm. Comparisonwith a Classical Approach 62

Maria Pia Francescato, Milos Ajcevic, Valentina Cettolo, Mario Canciani,and Agostino Accardo

Gait Phase Classification from Surface EMG Signals UsingNeural Networks 75

Christian Morbidoni, Lorenzo Principi, Guido Mascia, Annachiara Strazza,

Federica Verdini, Alessandro Cucchiarelli, and Francesco Di Nardo

Combining Objective Response Detectors UsingGenetic Programming 83

Leonardo Bonato Felix, Quenaz Bezerra Soares,

Antonio Mauricio Ferreira Leite Miranda de Sa,

and David Martin Simpson

Handwriting Kinematic Differences Between Copying

and Dictation 93

Silveri Giulia and Accardo Agostino

Bradycardia Assessment in Preterm Infants 100

Agnese Sbrollini, Martina Mancinelli, Ilaria Marcantoni,

Micaela Morettini, and Laura Burattini

To What Extent Does Heart Rate Alter the Cerebral

Hemodynamic Patterns During Atrial Fibrillation? 108

Stefania Scarsoglio, Luca Ridolfi, Andrea Saglietto,and Matteo Anselmino

Non-invasive Intrauterine Pressure Estimation Based on Nonlinear

Parameters Computed from the Electrohysterogram 117

Monica Albaladejo-Belmonte, Gema Prats-Boluda, Yiyao Ye-Lin,Carlos Benalcazar-Parra, Angel Lopez, Alfredo Perales,and Javier Garcia-Casado

Linear and Non-linear Analysis of EEG During Sleep Deprivationin Subjects with and Without Epilepsy 125

Silvia Marino, Giulia Silveri, Lilla Bonanno, Simona De Salvo,Emanuele Cartella, Aleksandar Miladinovic, Milos Ajcevic,and Agostino Accardo

Contents xxiii

Brain Oscillatory Activity and Neurological Deficit in Hyper-acuteIschemic Stroke: Correlation of EEG Changes with NIHSS 133

Milos Ajcevic, Giovanni Furlanis, Lara Stragapede, Mariana Ridolfi,Paola Caruso, Marcello Naccarato, Agostino Accardo,

and Paolo Manganotti

Differences in Circadian Rhythms of Blood Pressure and Heart

Rate Among Hypertensive and Normal Blood Pressure Subjects 142

Silveri Giulia, Pascazio Lorenzo, Sabbadini Gastone, Guerra Monica,

and Accardo Agostino

Ectopic Beat Detection from Wrist Optical Signals for Sinus

Rhythm and Atrial Fibrillation Subjects 150

Serj Haddad, Jarkko Harju, Adrian Tarniceriu, Tuomas Halkola,Jakub Parak, Ilkka Korhonen, Arvi Yli-Hankala, and Antti Vehkaoja

Electrocardiographic Alternans: A New Approach 159

Ilaria Marcantoni, Dalila Calabrese, Giorgia Chiriatti, Roberta Melchionda,

Benedetta Pambianco, Giulia Rafaiani, Eleonora Scardecchia,

Agnese Sbrollini, Micaela Morettini, and Laura Burattini

Co-activation of Knee Muscles in Female vs. Male Adults 167

Francesco Di Nardo, Annachiara Strazza, Andrea Tigrini, Guido Mascia,

Stefano Cardarelli, Alessandro Mengarelli, Federica Verdini,and Sandro Fioretti

Automatic Segmentation of Bipolar EHGs' Contractions UsingWavelet Transform 174

Amer Zaylaa, Ahmad Diab, Ziad Fawal, Mohamad Khalil,and Catherine Marque

Methods for Removing of Line Noise Artifact from EEG Records

with Minimization of Neural Information Loss 184

Jan Strobl, Marek Piorecky, Vlastimil Koudelka, Tomas Nagy,and Vladimir Krajca

Pilot Study for Estimating Physical Fatigue Based on Heart Rate

Variability and Reaction Time 193

Ardo Allik, Kristjan Pilt, Moonika Viigimae, and Ivo Fridolin

Characterization of Eye Gaze and Pupil Diameter Measurements

from Remote and Mobile Eye-Tracking Devices 201

Riccardo Lolatto, Giulia Rocco, Riccardo Mustoni, Chiara Maninetti,Riccardo Pastura, Andrea Pigazzini, and Riccardo Barbieri

xxiv Contents

Efficacy of Time- and Frequency-Domain Heart Rate

Variability Features in Stress Detection and Their Relation

with Coping Strategies 209

Pierluigi Reali, Agostino Brugnera, Angelo Compare,and Anna Maria Bianchi

Influence of Physical Models of Electrodes on Rat's Head

Forward Modelling 217

David Kuratko, Jaroslav Lacik, Zbynek Raida, Daniel K. Wojcik,and Vlastimil Koudelka

Improvement of Sleep Spindle Detection

by Aggregation Techniques 226

Elizaveta Saifutdinova, Daniela Dudysova, Vaclav Gerla,

and Lenka Lhotska

Preprocessing Pipeline for fNIRS Data in Children 235

Caterina Piazza, Andrea Bacchetta, Alessandro Crippa, Maddalena Mauri,

Silvia Grazioli, Gianluigi Reni, Maria Nobile, and Anna Maria Bianchi

Wavelet Analysis-Based Reconstruction for sEMG

Signal Denoising 245

Annachiara Strazza, Federica Verdini, Alessandro Mengarelli,Stefano Cardarelli, Andrea Tigrini, Sandro Fioretti,

and Francesco Di Nardo

An Information-Theoretical Method for Emotion Classification 253

Susana Bras, Joao M. Carvalho, Filipa Barros, Claudia Figueiredo,Sandra C. Soares, and Armando J. Pinho

Potential Biomechanical Overload on Skeletal Muscle Structures

in Students During Walk with Backpack 262

Giovanni D'Addio, Leandro Donisi, Luca Mercogliano,Giuseppe Cesarelli, Paolo Bifulco, and Mario Cesarelli

Accurate Calculation of Heart Period and Pulse Wave

Transit Time 267

Peter Nagy and Akos Jobbagy

Long-Term Stability of EEG Spectral AsymmetryIndex - Preliminary Study 276

Tuuli Uudeberg, Laura Paeske, Toomas Pold, Jaanus Lass, Hiie Hinrikus,

and Maie Bachmann

Regular Sessions: Biomedical Imaging and Image Processing

Flow Convergence Area Estimation on In Vitro Color Flow

Doppler Images Using Deep Learning 285

Grigorios-Aris Cheimariotis, Kostas Haris, Jeesoo Lee, Brent E. White,

Aggelos K. Katsaggelos, James D. Thomas, and Nikolaos Maglaveras

Contents xxv

Automated Design of Efficient Supports in FDM 3D Printing

of Anatomical Phantoms 292

Maria Agnese Pirozzi, Emilio Andreozzi, Mario Magliulo, Paolo Gargiulo,Mario Cesarelli, and Bruno Alfano

Diffusion Weighted Magnetic Resonance Imaging Texture

Biomarkers for Breast Cancer Diagnosis 301

Marialena I. Tsarouchi, Georgios F. Vlachopoulos, Anna N. Karahaliou,

and Lena I. Costaridou

Modeling Functional Processes of Brain Tissue: An fMRI Study

on Patients with Un-Medicated Late-Onset Restless Leg Syndrome ....306

Amalia K. Ntemou, Evanthia E. Tripoliti, Persefoni N. Margariti,Maria I. Argyropoulou, and Dimitrios I. Fotiadis

Shift-Compensated Volumetric Interpolation of Tomographic

Sequences for Accurate 3D Reconstruction 312

Chiara Santarelli, Francesca Uccheddu, Fabrizio Argenti,Luciano Alparone, Monica Carfagni, and Lapo Governi

Calculating Texture Features from Mammograms and Evaluating

Their Performance in Classifying Clusters of Microcalcifications 322

Marcelo A. Duarte, Wagner C. A. Pereira, and Andre Victor Alvarenga

LNDetector: A Flexible Gaze Characterisation Collaborative

Platform for Pulmonary Nodule Screening 333

Joao Pedrosa, Guilherme Aresta, Joao Rebelo, Eduardo Negrao,Isabel Ramos, Antonio Cunha, and Aurelio Campilho

Physical Breast Phantom Dedicated for Mammography Studies 344

Firgan Feradov, Stoyko Marinov, and Kristina Bliznakova

Segmentation of Pulmonary Nodules in CT Images Usingthe Sliding Band Filter 353

Joana Rocha, Antonio Cunha, and Ana Maria Mendonca

Method for Finding the Limits of Blood Vessel Landmarks in EyeFundus Images Based on Distances in Graphs: Preliminary Results

. . .358

Martynas Patasius, Jurate Simkiene, Daivaras Sokas,

and Andrius Pranskunas

Anthropomorphic Physical Breast Phantom Based on Patient

Breast CT Data: Preliminary Results 367

Sivo Daskalov, Nikiforos Okkalidis, John M. Boone, Stoyko Marinov,

Zhivko Bliznakov, Giovanni Mettivier, Hilde Bosnians, Paolo Russo,

and Kristina Bliznakova

xxvi Contents

Microcalcification Cluster SDNR in Synthesizedand 2D Mammography 375

Andreas Petropoulos, Spyros Skiadopoulos, Anna Karahaliou,

Georgios Vlachopoulos, Gerasimos Messaris, and Lena Costaridou

Enhancing CT 3D Images by Independent Component Analysisof Projection Images 381

Markus Hannula, Jari A. K. Hyttinen, and Jarno M. A. Tanskanen

Potentials of OCT in Monitoring Ocular Hemodynamicsof Patients with Primary Open Angle Glaucoma 390

E. N. Iomdina, D. D. Khoziev, A. A. Kiseleva, P. V. Luzhnov,O. A. Kiseleva, and D. M. Shamaev

Automatic Segmentation of Bone and Muscle Structures in CT

Volumes Using Convex Relaxation and Fine-Tuning 397

Jose-Antonio Perez-Carrasco, Carmen Serrano, and Begona Acha

A Comparison of Denoising Algorithms for Effective EdgeDetection in X-Ray Fluoroscopy 405

Emilio Andreozzi, Maria Agnese Pirozzi, Antonio Sarno,Daniele Esposito, Mario Cesarelli, and Paolo Bifulco

Stereophotogrammetric Basic Framework for Postural Assessment.... 414

Alice Fontes and Mauricio Cagy

Dermoscopic Image Segmentation: A Comparison of Methodologies ...421

Paulina Velez Nunez, Carmen Serrano, Begona Acha,

and Jose Antonio Perez-Carrasco

Quantitative Analysis of Brain 18F-fluordesoxyglucoseand Early-Phase 18F-florbetapir Positron Emission Tomography 427

Alexander P. Seiffert, Adolfo Gomez-Grande, Patricia Sanchez-Gonzalez,

Walid Dghoughi, Alberto Villarejo-Galende, Hector Bueno,

and Enrique J. Gomez

Regular Sessions: Bioinstrumentation, Biosenso

and Bio-micro/nano Technologies

Cardiac Pacemaker Exposed to ElectroporationPulses - An Ex Vivo Study 439

Tomaz Jarm, Tadej Krmac, Damijan Miklavcic, and Ratko Magjarevic

Smart Vest for Respiratory and Physical Activity Monitoringin COPD Patients 447

David Naranjo-Hernandez, Javier Reina-Tosina, Laura M. Roa,

Gerardo Barbarov-Rostan, Alejandro Talaminos-Barroso,

Pilar Cejudo-Ramos, Eduardo Marquez-Martin, and Francisco Ortega-Ruiz

Contents xxvii

A Prototype of Intelligent Portable Oxygen Concentrator

for Patients with COPD Under Oxygen Therapy 455

Alejandro Lara-Dona, Daniel Sanchez-Morillo, Maria Perez-Morales,

Miguel Angel Fernandez-Granero, and Antonio Leon-Jimenez

Optical Metrology of Novel Optically Stimulated Semiconductor

Gas Sensor 462

Yuri Dekhtyar, Maksims Komars, and Maksims Sneiders

Regular Sessions: Bioinformatics, Computational Biology

and Systems Biology

Dose-Response Curve: Temporal Dynamics of RespiratoryMechanics in Mice 471

Otavio Henrique F. Ledesma, Renato L. Vitorasso,

Maria Aparecida de Oliveira, and Henrique Takachi Moriya

Influence of Astrocytic Gap Junction Coupling on in Silico

Neuronal Network Activity 480

Barbara Genocchi, Kerstin Lenk, and Jari Hyttinen

Heart Closed-Loop Model for the Assessment of Cardiac Pacing 488

Niccolo Biasi and Alessandro Tognetti

Model-Based Assessment of Sex Differences in Glucose

Effectiveness and Its Components 500

Micaela Morettini, Ludovica Hari, Christian Gobi,

Alexandra Kautzky-Willer, Andrea Tura, Giovanni Pacini,

and Laura Burattini

Insulin Clearance in Women with a History of Gestational

Diabetes Assessed by Mathematical Model Analysesof Intravenous Glucose Tolerance Test 508

Micaela Morettini, Christian Gobi, Alexandra Kautzky-Willer,Giovanni Pacini, Andrea Tura, and Laura Burattini

Computational Models for Predicting Resilience Levels

of Women with Breast Cancer 518

Konstantina Kourou, Haridimos Kondylakis, Lefteris Koumakis,

Georgios C. Manikis, Kostas Marias, Manolis Tsiknakis,

Panagiotis G. Simos, Evangelos Karademas, and Dimitrios I. Fotiadis

A Systems Biology Approach to Decipher Genetic Variants

in a Canine Model of Sudden Cardiac Death 526

Martina Vescio, Lia Crotti, Peter Schwartz, and Linda Pattini

xxviii Contents

Computational Fluid Dynamics Study of Inlet Velocity

on Extrusion-Based Bioprinting 531

Juan Carlos Gomez-Bianco, Enrique Mancha-Sanchez,

Juan Francisco Ortega-Moran, Antonio Diaz-Parralejo,Francisco Miguel Sanchez-Margallo, and Jose Bias Pagador-Carrasco

A System to Assist in the Training of Medical Students

in Respiratory Diseases 541

Alejandro Talaminos-Barroso, Javier Reina-Tosina, Laura M. Roa,

David Naranjo-Hernandez, Gerardo Barbarov-Rostan,

Pilar Cejudo-Ramos, Eduardo Marquez-Martin, and Francisco Ortega-Ruiz

Effects of Arterial and Tracheal Pressures During a Respiratory

Mechanics Protocol in Spontaneously Hypertensive Rats 551

Amanda N. Barros, Vitor A. Takeuchi, Felipe Fava de Lima,

Raissa R. S. Amorim, Otavio Henrique F. Ledesma,

Maria Aparecida de Oliveira, Henrique T. Moriya, and Renato Vitorasso

Modeling of Carbohydrates Oxidation Rate During Exercise

in Type 1 Highly-Trained Diabetic Patients 559

Maria Pia Francescato, Milos Ajcevic, Alex Buoite Stella,

and Agostino Accardo

Regular Sessions: Biomechanics, Robotics and Rehabilitation

Pressurization of Axially Prestretched Tube: Consequencesfor Arterial Mechanics 569

Zdenek Petrivy and Lukas Horny

A Closed-Loop Multiscale Model of the Cardiovascular System:

Application to Heart Pacing and Open-Loop Response 577

Caterina Gallo, Luca Ridolfi, and Stefania Scarsoglio

Experimental Study to Improve "Federica" Prosthetic Hand

and Its Control System 586

Daniele Esposito, Chiara Cosenza, Gaetano Dario Gargiulo,

Emilio Andreozzi, Vincenzo Niola, Antonio Fratini, Giovanni D'Addio,

and Paolo Bifulco

Study on the Activation Speed and the Energy Consumptionof "Federica" Prosthetic Hand 594

Daniele Esposito, Sergio Savino, Chiara Cosenza, Gaetano Dario Gargiulo,

Antonio Fratini, Giuseppe Cesarelli, and Paolo Bifulco

New Method to Analyze the Load Propagation on the Plantar

Foot Surface During a Walk/Run Using the Smart Sock System 604

Alexander Okss, Alexei Katashev, Peteris Eizentals, Sandra Rozenstoka,

and Dace Suna

Contents xxix

Intergame Analysis of Upper Limb Biomechanics of Stroke

Patients in Real and Virtual Environment

Herta Costa, Aline Fernandes, Debora Oliveira, Jamilson Brasileiro,

Tatiana Ribeiro, Edgar Vieira, and Tania Campos

The Effect of Perturbation Time on Selected Spatio-TemporalParameters of Gait

Andrej Olensek, Matjaz Zadravec, and Zlatko Matjacic

618

610

Design of a Hybrid Portable System for Measuring the Position

of the Spine, Pelvis and Center of Gravity of the BodyJan Hejda, Petr Volf, Monika Bacikova, Noa Bar, Cestmir Oberman,

Kristyna Rusnakova, Marcela Braunova, and Patrik Kutilek

622

The Evaluation of the Joint Quasi-Stiifness Duringthe Robot-Assisted Gait Training: A Pilot StudyLuigi Iuppariello, Maurizio Nespoli, Fernanda Iammarone,

Marianna Bertella, Ilaria Riccio, Marianna Cardillo, Angela Natalizio,Fabrizio Clemente, and Mario Cesarelli

634

Design of Device for Measuring the Load of Cross-CountrySki Poles 640

Jan Hejda, Petr Volf, Jakub Mejstfik, Jan Hybl, Ales Tvrznik,David Gerych, Tomas Michalek, Cestmir Oberman, Emil Bolek,

and Patrik Kutilek

Regular Sessions: Therapeutic and Diagnostic Systems, Devices

and Technologies and Clinical Engineering

A Risk Stratification Model for Early Cognitive ImpairmentAfter Diagnosis of Parkinson's Disease 653

Kostas M. Tsiouris, Spiros Konitsiotis, Dimitrios D. Koutsouris,

and Dimitrios I. Fotiadis

Upper Limp Movement Analysis of Patients with Neuromuscular

Disorders Using Data from a Novel Rehabilitation

Gaming Platform 661

Achilleas Chytas, Dimitris Fotopoulos, Vassilis Kilintzis,

Theodoros Loizidis, and Ioanna Chouvarda

3D Acquisition of the Ear Anatomy: A Low-Cost Set up Suitable

for the Clinical Practice 669

Rocco Furferi, Elisa Mussi, Michaela Servi, Francesca Uccheddu,

Yary Volpe, and Flavio Facchini

xxx Contents

Machine Learning Classification of Females Susceptibilityto Visceral Fat Associated Diseases 679

Mahmoud Aldraimli, Daniele Soria, James Parkinson, Brandon Whitcher,

E. Louise Thomas, Jimmy D. Bell, Thierry J. Chaussalet,

and Miriam V. Dwek

A Study on Relationship Between Walking Speed and Acceleration

of Center of Mass Estimated with Inertial Sensors 694

Takashi Watanabe and Yuho Takeda

Comparative Assessment Between 3D and Conventional

2D Imaging Systems in Laparoscopic Practice 703

Juan A. Sanchez-Margallo, Silvia Enciso Sanz,

and Francisco M. Sanchez-Margallo

Modeling of Transpalpebral Tonometry System for Parameters

Optimization of the Measuring Sensor 711

P. V. Luzhnov, E. N. Iomdina, K. V. Ivanishchev, D. M. Shamaev,

and A. A. Kiseleva

A Feasibility Test of Evaluation of Gait Movement by UsingCenter of Mass Estimation with Inertial Sensors 718

Yuho Takeda and Takashi Watanabe

Controlled Thoracic Motions of an Anthropomorphic Phantom

for Myocardial Perfusion Imaging 727

Sotiris Panagi, Antonis Antoniou, Isabelle Chrysanthou-Baustert,Demetris Kaolis, Ourania Demetriadou, Costas Kyriacou,and Yiannis Parpottas

3D Printing-Based Pediatric Trainer for Ultrasound-Guided

Peripheral Venous Access 735

Rocco Furferi, Lorenzo Guariento, Kathleen S. McGreevy, Elisa Mussi,

Niccolo Parri, Francesca Uccheddu, and Yary Volpe

Pectus Excavatum: A New Approach for Monitoring

Cup-Suction Treatment 746

Francesco Buonamici, Antonio Marzola, Michaela Servi,

Francesca Uccheddu, Yary Volpe, Marco Ghionzoli,

and Antonio Messineo

ARTE Project: EEG Analysis During Robotic Rehabilitation 755

Alessandra Calcagno, Stefania Coelli, Giulia Tacchino, Marta Baratto,

Franco Molteni, Eleonora Guanziroli, Cosimo Puttilli,

and Anna Maria Bianchi

Contents xxxi

Bioimpedance, Total Body Water and Phase Angle of Preschool

Czech Children: Preliminary Study 761

Jan Hlubik, Lenka Vyslouzilova, Lenka Lhotska, Olga Stepankova,and Jan Kriz

TOF-Watch NMB Monitoring Misleading Display Output DuringModerate Neuromuscular Blockade 768

Mafalda Couto, Catarina S. Nunes, Pedro Amorim, and Joaquim Mendes

Device for Measuring Protection in Sunglasses Against Harmful

Blue Light 776

Artur D. Loureiro and Liliane Ventura

Backscattered Ultrasound Periodicity Characterization

on Trabecular Bone-Mimicking Phantoms: A Spectraland Wavelets Approach 780

Christiano Bittencourt Machado, Mahmoud Meziri,

Wagner Coelho de Albuquerque Pereira, and Guillermo Cortela

Short-Term Hemodynamic Variability in Supine and Tilted

Position in Young Men 787

Gerard Cybulski, Edward Kozluk, Agnieszka Piatkowska, Ewa Michalak,

Anna Stepniewska, Anna Gasiorowska, and Wiktor Niewiadomski

Efficacy of Machine Learning in Predicting the Kind of Delivery

by Cardiotocography 793

Giovanni Improta, Carlo Ricciardi, Francesco Amato,

Giovanni D'Addio, Mario Cesarelli, and Maria Romano

Analysis of the Effect of Natural and Simulated Sun Exposure

on Sunglasses Lenses: A Study on Materials Degradation 800

Leonardo Mariano Gomes, Mauro Masili, and Liliane Ventura

Eye Scan Ultrasound System for Automatic Cataract Detection:

From a Preclinical to a Clinical Prototype 811

Lorena Petrella, Marco Gomes, Fernando Perdigao, Mario Santos,

Paulo Fernandes, Carlos Pinto, Sandrina Nunes, Miguel Morgado,Miguel Caixinha, and Jaime Santos

Regular Sessions: Information Technology in Health Systems

Utilizing Incremental Learning for the Prediction of Disease

Outcomes Across Distributed Clinical Data: A Framework

and a Case Study 823

Vasileios C. Pezoulas, Themis P. Exarchos, Konstantina D. Kourou,

Athanasios G. Tzioufas, Salvatore De Vita, and Dimitrios I. Fotiadis

xxxii Contents

EmERGE Platform: A New mHealth Solution for People

Living with HIV 832

Paloma Chausa, Francisco J. Garate, Cesar Caceres, Edward Wallitt,Jennifer Whetham, and Enrique J. Gomez

Machine Learning Algorithms Predict Body Mass Index UsingNonlinear Trimodal Regression Analysis from Computed

Tomography Scans 839

Marco Recenti, Carlo Ricciardi, Magnus Gislason, Kyle Edmunds,

Ugo Carraro, and Paolo Gargiulo

Is It Possible to Predict Cardiac Death? 847

Carlo Ricciardi, Valeria Cantoni, Roberta Green, Giovanni Improta,and Mario Cesarelli

On the Privacy Enhancement of In-Transit Health

Data Inspection: A Preliminary Study 855

Jorge Sancho, Gert Laess0e Mikkelsen, Jonas Lindstrom, Jose Garcia,

and Alvaro Alesanco

rOral: Use of a Teledentistry System for Remote ImagesAssessment in Oral Health Education Workflows 861

Raquel Sebastiao, IHdio C. Oliveira, Ricardo Felgueiras,and Nelio J. Veiga

Investigations on a Computer Application for Tracking the Mean

Glandular Breast Dose Profile in Mammography 869

Homero Schiabel, Bruno Barufaldi, and Eny M. Ruberti Filha

Cuffless Blood Pressure Estimation Only an iPhone:

Investigation on Cold Pressor Tests 874

Ippei Harada, Noriyuki Mochizuki, Peter Rolfe, Masahiro Shibata,and Takehiro Yamakoshi

The UBORA E-Infrastructure for Open Source Innovation

in Medical Technology 878

Carmelo De Maria, Licia Di Pietro, Andres Diaz Lantada, Alice Ravizza,

Mannan Mridha, Janno Torop, June Madete, Philippa Makobore,

and Arti Ahluwalia

Design and Implementation of a Web-Based Platform to SupportResearch in X-Ray Breast Imaging 883

Adelina Doycheva, Nikolay Dukov, and Kristina Bliznakova

Empowering Diabetic Patients Using Gadgets and Mobile App 891

Sara Zulj, Goran Seketa, Dominik Dzaja, Luka Celic, Igor Lackovic,

and Ratko Magjarevic

Contents xxxiii

A New Software Tool for Analyzing Mental Health Data

in a Spanish Region 898

Diego Calvo Barreno, Susel Gongora Alonso, Isabel de la Torre Diez,

Miguel Lopez Coronado, and Manuel Franco

Feasibility of Machine Learning in Predicting Features Related

to Congenital Nystagmus 907

Giovanni D'Addio, Carlo Ricciardi, Giovanni Improta, Paolo Bifulco,

and Mario Cesarelli

A Smartphone Based Survey to Investigate the Cyber-RiskPerception on the Health-Care Professionals 914

Daniele Giansanti, Mauro Grigioni, Lisa Monoscalco,and Rosario Alfio Gulino

ICT4MOMs: An ICT Integrated Approach to Monitor

and Manage Pregnancy Development 924

Maria G. Signorini, Nicolo Pini, Danilo Pani, and Giovanni Magenes

Regular Sessions: Assistive Technologies

Smart Shirt for Uncontrolled Movement Retraining 933

Peteris Eizentals, Alexei Katashev, Alexander Oks, and Guna Semjonova

Computational Fluid Dynamics of Blood Flow at the Left Atrium

and Left Atrium Appendage 938

Grigoris I. Grigoriadis, Antonis I. Sakellarios, Katerina Naka,

Ioanna Kosmidou, Christopher Ellis, Lampros K. Michalis,

and Dirnitrios I. Fotiadis

Powered Wheelchair Impact - User-Centered Observational Study.... 947

Ines Domingues, Joao Pinheiro, Joao Silveira,and Anabela Correia Martins

Virtual Assistant Prototype for Managing Medication UsingMessaging Platforms 954

Surya Roca, Manuel Hernandez, Jorge Sancho, Jose Garcia,

and Alvaro Alesanco