October 17th-20th Phuket Island, Thailand · modern four-star Phuket Hotel and beach Resort, located at Patong Beach, Thailand Phuket is the world renowned as the “Pearl of the

THE 10th BIENNIAL MEETING

OF THE ASIA-PACIFIC SOCIETY

FOR NEUROCHEMISTRY (APSN) 2010

October 17th-20th, 2010Phuket Island, Thailand

Venue : Phuket Graceland Resort and Spa

Local Organizers : Thai Neuroscience Society

Mahidol University

in conjunction with

15th THAI NEUROSCIENCE SOCIETY CONFERENCE

Program at a Glance

Farewell banquetOpening reception18.00

SYM #8Validation and molecular

mechanism of schizophrenia and

depression

SYM #4Astrocyte in diseases

TNS business meeting16.30-17.30

SYM #7Regulation of

oligodendrocytedevelopment and

myelination

SYM #3Drug discovery for

Alzheimer’s disease: complexes and targets

SymposiaSymposia16.00-18.00

Coffee

Special lecture: Aryeh Routtenberg

15.30-16.30

Coffee15.30-16.00

APSN business meeting

14.30-15.30

CoffeeYIC #2Neuronal Plasticity and

Circadian Rhythm (tentative title)

YIC #1Mechanisms of

diseases (tentative title)

APSN council meeting14.00-17.00

Poster prize presentation

Special lecture: Setou13.30-14.30

Young investigator colloquia13.30-15.30

Lunch, poster viewing and exhibition

Lunch, poster viewingand exhibition

Lunch, poster viewing and exhibition12.00-13.30

SYM #6Ins and outs of cell fate

determination in thecentral nervous system

YIC #4Glia cells in health and

disease

SYM #2New players in the

molecular pathogenesis of amyotrophic lateral

sclerosis

SYM #5The Chloride ion and

cell signaling in neurobiology

YIC #3Stem cell

SYM #1Cell therapy for

Parkinson’s disease

SymposiaYoung investigator colloquiaSymposia10.00-12.00

Coffee, poster viewing and exhibition

Coffee, poster viewingand exhibition

Coffee, poster viewing and exhibition09.30-10.00

Plenary #3Kyungjin Kim

Plenary #2Hideyuki Okano

Plenary #1Glenda Halliday08.30-09.30

October 20October 19October 18October 17Time

Farewell banquetOpening reception18.00

SYM #8Validation and molecular

mechanism of schizophrenia and

depression

SYM #4Astrocyte in diseases

TNS business meeting16.30-17.30

SYM #7Regulation of

oligodendrocytedevelopment and

myelination

SYM #3Drug discovery for

Alzheimer’s disease: complexes and targets

SymposiaSymposia16.00-18.00

Coffee

Special lecture: Aryeh Routtenberg

15.30-16.30

Coffee15.30-16.00

APSN business meeting

14.30-15.30

CoffeeYIC #2Neuronal Plasticity and

Circadian Rhythm (tentative title)

YIC #1Mechanisms of

diseases (tentative title)

APSN council meeting14.00-17.00

Poster prize presentation

Special lecture: Setou13.30-14.30

Young investigator colloquia13.30-15.30

Lunch, poster viewing and exhibition

Lunch, poster viewingand exhibition

Lunch, poster viewing and exhibition12.00-13.30

SYM #6Ins and outs of cell fate

determination in thecentral nervous system

YIC #4Glia cells in health and

disease

SYM #2New players in the

molecular pathogenesis of amyotrophic lateral

sclerosis

SYM #5The Chloride ion and

cell signaling in neurobiology

YIC #3Stem cell

SYM #1Cell therapy for

Parkinson’s disease

SymposiaYoung investigator colloquiaSymposia10.00-12.00

Coffee, poster viewing and exhibition

Coffee, poster viewingand exhibition

Coffee, poster viewing and exhibition09.30-10.00

Plenary #3Kyungjin Kim

Plenary #2Hideyuki Okano

Plenary #1Glenda Halliday08.30-09.30

October 20October 19October 18October 17Time

Organizing Committee

Chair of the Program CommitteeAkio Wanaka (Japan)

International Program CommitteeAkio Wanaka (Japan)Prakash Babu Phanithi (India)Rashmi Bansal (USA)Kazuhiro Ikenaka (Japan)Andrew Lawrence (Australia)Woong Sun (Korea)

Advisory CommitteeSkorn MongkolsukKanokwan TilokskulchaiPavich Tongroach Naiphinich KotchabhakdiRatree Sudsuang

Piyarat Govitrapong (Chair)Sukumal Chongthammakun (Co-chair)Pansiri Phansuwan-Pujito (Co-chair)Banthit Chetsawang (Secretariat)Pavich Tongroach Naiphinich KotchabhakdiAnan SrikiatkhachornKanokwan TilokskulchaiBoonyong Tantisira Yupin SanvarindaSupin ChompoopongThongchai Sooksawate Kittisak YokthongwattanaSukonthar NgampramuanSujira Mukda

Andrew J. Lawrence (Treasurer)Peter Dunkley Piu Chan Babu P. Prakash (Secretary) Mitradas M. PanickerKazuhiro Ikenaka (President)Akio Wanaka Katsuhiko YanagisawaYukio Yoneda Yoo-Hun Suh Peter T.H. Wong Piyarat Govitrapong Rashmi Bansal

APSN Council Local Organizing Committee

Local Organizing Committee

Plenary Speakers

Glenda Halliday, Ph.D. is a NHMRC Principal Research Fellow, Prince of Wales Medical ResearchInstitute, and a Conjoint Professor, School of Medical Sciences, University of New South Wales, and an Honorary Visiting Scientist, Westmead Hospital, Concord Hospital. She is an internationally renowned expert in the pathogenesis of neurodegenerative disorders having published a large body of work on animal and human neuroanatomy and neuropathology, and on molecular, functional and longitudinal brain changes (226 peer reviewed journal articles with >5,000 citations). Her Ph.D. and subsequent postdoctoral work on the anatomy and pathology of dopamine systems and other brainstem monoamine systems in controls and patients with Parkinson's disease revealed that more than thedopamine system was damaged in this disorder, and her research has focused on understanding how this occurs. Her pathological work on dementia with Lewy bodies has been incorporated into highly cited research criteria for the diagnosis of this disorder, highlighting the association between Lewy body deposition and visual hallucinations (rather than to a loss of function). Her more recent collaborative work on frontotemporal dementia has determined survival patterns and the pathological progression for this disorder.

Hideyuki Okano received his M.D. from Keio University School of Medicine in 1983 and received his Ph.D. in medical science in 1988 from the Keio University Graduate School of Medicine for his work in molecular genetic studies of myelin defi cient mutant mice. From 1989 to 1991, Hideyuki Okano joined the Department of Biological Chemistry at the Johns Hopkins University School of Medicine in USA as a postdoctoral fellow and was involved in the study of developmental neurobiology of Drosophila. He was appointed as a professor at the Laboratory of Molecular Neurobiology, Tsukuba University in 1994. In 1997, he was appointed as a professor at the Osaka University Medical School (Graduate School of Medicine) and he started his study of stem cells and regenerative medicine of the central nervous system

(CNS). In 2001, he was appointed as professor at Department of Physiology, Keio University School of Medicine and he has been a leader of the 21st century Center of Excellence program "Basic Study and Clinical Application of the Human Stem Cell Biology and Immunology" since 2003. He has been a Dean of Graduate School of Medicine, Keio University from 2007. His research focuses on analyzing the molecular and cellular fundamentals of nervous system, with the fi nal goal of this being the application of these understandings to the regulation of stem cell systems and regeneration of the CNS.

Kyungjin Kim, Ph.D., is currently professor at Department of Biological Sciences, Seoul National University and director of the Brain Research Center (BRC), 21st century frontier program in neuroscience

supported by the Ministry of Education, Science and Technology (MEST) of Korean government. Prior to joining Seoul National University, he did post-doctoral works at University of Illinois and Columbia University.

He resumed assistant professor at Department of Zoology (renamed Molecular Biology and currently BiologicalSciences) of Seoul National University and was promoted as associate and full professor. He is a well known

neuroendocrinologist who has worked with a pivotal neurohormone such as GnRH in a variety of experimental setting.

He provided the fi rst evidence on GnRH mRNA splicing machinery and the molecular reasons for the mystery of a nature’s knockout, hopogonadal (hpg) mouse. He is also working with different disciplines such

as neurobiology of maternal stress, and neurobiology of clock machinery, in particular, Clock:Bmal1 core

clock machinery, ultradian rhythm in the hypothalamus (GnRH pulse generator) and a local circadian rhythm of glucocorticoid from adrenal gland. He published about 140 peer-reviewed international articles and about

40 domestic articles, and invited chapters in books. He has served on numerous society business, editorial board members and committee review panels in government and private sectors. He was also founder of

Neurogenex bioventure and remained CEO from 2000 until 2003.

Kyungjin Kim

Glenda Halliday

Hideyuki Okano

Daily Topic

Invited symposium includes:

Cell therapy for Parkinson’s disease • Perspectives on the clinical experience • Transgenic reporter mice as tools for grafting studies • Axonal growth guidance mechanisms for midbrain dopamine neurons • Stem cell therapy for PD

New players in the molecular pathogenesis of amyotrophic lateral sclerosis• Misfolded superoxide dismutase-1 and amyotrophic lateral sclerosis• Molecular genetic insights into ALS• Pathomechanism of mutant VAPB-mediated ALS: a missing link between sporadic and familial ALS?• Expression of the SMA determining factor, survival motor neuron, modulates the ALS phenotype

Drug discovery for Alzheimer’s disease: complexes and targets• New discoveries in neurodegeneration and their support for drug targets• Natural products as drugs: A new hope• Novel biochemical pathways needs to be identifi ed as drug targets• A debate on environmentally (Al-maltol) induced aged rabbit as AD animal model: a debate on hope in drug discovery

Ins and outs of cell fate determination in the central nervous system• The role of signaling molecules in neural development in the retina• Control of neural cell proliferation and differentiation in the developing cerebellum• Neuroregeneration in the adult central nervous system• Neural stem and progenitor cells in the embryonic and adult CNS

Regulation of oligodendrocyte development and myelination• Control of early oligodendrocyte development by local cell-cell interactions • Disruption of axo-glial interaction causes alteration of axonal transport• Signaling pathways regulating myelination• Thyroid Hormone and regulation of gene expression in the adult mammalian brain-relevance to oligodendrocyte development

Validation and molecular mechanism of schizophrenia and depression• The relationships between adult neurogenesis and depression using Dcx-CreER; Rosa26fl oxed-DTA mouse • The validation of schizophrenia diagonized by DSM• Molecular links between schizophrenia and mitochondria • The associations between reactive oxygen species related gene polymorphisms and tardive dyskinesia in schizophrenia

ISN/APSN SchoolOctober 11th to 15th, 2010

APSN School Chair: Dr. Alfreda Stadlin

ISN/APSN School will be held before the APSN symposium from October 11th to 15th, 2010 at Center for Neuroscience, Faculty of Science, Mahidol University, Bangkok in a theme of Drug Addiction. The main objective of the School is to enable graduate students and junior post-doctoral fellows from the Asia-Pacifi c region to meet in an environment where they can acquire knowledge on recent advances in neurochemistry research and for them to have a platform from which to gain practical experience on neuroscience techniques.

The School will cover lectures, practical seminarsand a variety of laboratory projects. These will focuson several technique-oriented areas of addiction

research.

School program (day by day activities):

Group 1 – Neural stem cell isolation/culture

Group 2 – HPLC/receptor bindingGroup 3 – Immunocytochemistry/Western blot

Group 4 – Proteomics - 2D gel

Group 5 – Real time RT/PCRGroup 6 – Genotyping

Deadline for applications is July 1, 2010. All successful applicants will be advised by email by

August 16, 2010 and will be provided with 85%

travel support (cheapest train or airfare), food and accommodation during the entire time of the school

and APSN symposium (from 11th-20th October).

Download the application and more information are available now on the website: http://www.apsn2010.com/school.asp

Congress Venue

APSN 2010 will be held at PHUKET GRACELAND RESORT & SPA, the luxury modern four-star Phuket Hotel and beach Resort, located at Patong Beach, Thailand

Phuket is the world renowned as the “Pearl of the Andaman Sea” for its clean white sandy beaches and crystal clear blue sea.Phuket Graceland Resort & Spa with its

prime location overlooking the Andaman Sea

is the best resort in Patong beach with its

tropical beauty and geographic grandeur.

It is just 30 kms from Phuket International

Airport and 862 kms from Bangkok.

Graceland’s specious Conference and Banquet

room can comfortably accommodate up to 1,000 people,

tastefully decorated and equipped with hi-tech audio-visual systems and also Wi-Fi internet access in all rooms.

For more information on PHUKET GRACELAND RESORT & SPA

please visit www.phuketgraceland.com

RegistrationStart for Early Registration: Mar 30, 2010Deadline for Registration: July 1, 2010

Participants and accompanying persons are requested to register in advance by fi lling in the on-line Registration Form. In order to avoid double charges, please submit your registration ONCE. Early bird registration is open on the end of March and will be closed on July 1, 2010. After this date, a higher rate will be applied. The fees for registration are detailed in the table below.

For accompanying persons, the fees will include:• Welcome Reception• Farewell Dinner

Registration includes the following unless otherwise specifi ed:• Program booklet• Abstract book• Congress bag• Coffee or tea breaks• Welcome Reception• Farewell Dinner

Cancellation policy:

• Before and inclued August 1, 2010 refund less USD50 processing • After August 1, 2010 no refund will be possible

Call for Abstracts

The organizers would like to invite the submission of abstract for presentation at APSN 2010 meeting. The accepted abstracts will be published in the Journal of Neurochemistry. For more detail please visit our website.

** Deadline for Abstract Submission: May 30, 2010 **

Contact information

address: Center for Neuroscience, Faculty of Science, Mahidol University, Bangkok 10400, Thailandcongress website: www.apsn2010.comemail addresse: [email protected]

Cancellation policy:

USD0USD0USD0

Category

- Invited Speaker for Plenary, Symposium, Colloquium- APSN Council Member- APSN School attendee or Travel Award recipient- APSN Membership- Non-Membership- Student- Accompanying Person

Early Registration by July 1

USD200USD300USD100

Late Registration from July 2

USD250USD350USD150

Registration Fees

USD110

All registered delegates and accompanying persons are cordially invited to the following events which are covered by registration fee.

Opening reception

The welcome reception will be held on the fi rst congress evening. This evening will give you aninformal socializing opportunity with Thai and international food.

Exhibition

A commercial and non-commercial exhibitionwill be organized during the October 18th-20th of the congress.

Social Program

For more information on social events please visit www.apsn2010.com

Farewell Banquet

The Party will be the last highlight of the social events at the congress. A Thai Night will provide an opportunity for participants to experience with spectacular entertainment and special experience with fascinating Thai culture, music and Thai food.

http://www.apsn2010.com