Nuclear Medicine Physics Fleming JS Comparison of geometric mean with posterior view renography in the assessment of renal function Nucl ear Medicine Communications, 27, 2006, 305 Tossici-Bolt L, Hoffmann SM, Kemp PM, Metha RL, Fleming JS Quantification of [(123)I]FP-CIT SPECT brain images: an accurate technique for measuring the specific binding ratio Eur J Nucl Med Mol Imaging, in press, 2006, Fleming JS, Quint M, Bolt L, Martonen TB Conway JH Comparison of SPECT aerosol deposition data with twenty-four hour clearance measurements. Journal of Aerosol Medicine ., 2006, In press Bolt L Fleming JS, Conway JH Martonen TB An analytical technique to recover the third dimension in planar imaging of inhaled aerosols : (1) Impact on spatial quantification Journal of Aerosol Medicine, 2006, In press Bolt L, Fleming JS, Kemp PM The 3D fractal dimension of DaTSCAN images Nuclear Medicine Communications, 27, 2006, 296 Fleming JS Zivanovic MA, Blake GM, Burniston M Cosgriff PS Controversies in the estimation of glomerular filtration rate Nuclear Medicine Communications, 27, 2006, 407-408 Fleming JS, Pitcairn G, Newman S Defining the lung outline from a gamma camera transmission attenuation map Physics in Medicine and Biology, 51, 2006, 1791-1805 Fleming JS A Technique for analysis of geometric mean renography Nuclear Medicine Communications, 27, 2006, 701-708 Dawson AH, Fleming JS, Hoffmann SMA, Papaspurou L, Peel S Computer simulation of gamma camera images of the kidney Nuclear Medicine Communications, 27, 2006, 285 Fleming, J.S. Zivanovic M.A., Blake, G.M., Burniston M, Cosgriff P.S., Nunan, T.O. Guidelines for the measurement of glomerular filtration rate using plasma sampling Nuclear Medicine Communications, 26, 2005, 176-178 Fleming JS, Bolt, L. Conway, J.H., Quint M., Martonen, T.B Comparison of intra-pulmonary aerosol deposition by 3D imaging and 24 hour clearance Journal of Aerosol Medicine, 18, 2005, 104
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Nuclear Medicine Physics
Fleming JS
Comparison of geometric mean with posterior view renography in the assessment of renal function
The contribution of statistical parametric mapping in the assessment of precuneal and medial temporal lobe perfusion by Tc-99m-HMPAO SPECT in mild Alzheimer’s and Lewy body dementia
Nuclear Medicine Communications, 26, 2005, 1099-1106
Hofmann W, Sturm R, Fleming JS, Conway JH, Bolt L.
Simulation of three-dimensional particle deposition patterns in human lungs and comparison with experimental SPECT data.
Journal of Aerosol Science and Technology, 39, 2005, 771-781
Wilby SL, Fleming JS, Hoffmann SMA, Heinle F, Heinle I, Reid C, Misson S.
Enhancing the display of pulmonary embolism (PE) using planar scintigaphy
European Journal of Nuclear Medicine and Molecular Imaging, 32 Supplement 1, 2005, S212-S213
Validation of the conceptual anatomical model of the lung airway.
Journal of Aerosol Medicine, 17, 2004, 260-269
Fleming JS, Bolt L. Stratford JS, Kemp PM.
The specific uptake size index for quantifying radiopharmaceutical uptake
Physics in Medicine and Biology, 49, 2004, N227-N234
Fleming, J.S.
Measuring drug deposition by airway generation in humans
Dalby, R.N. Byron P.R, Peart J, Suman,J.D., Farr, S.J., Respiratory Drug Delivery IX, River Grove Illinois, Davis Healthcare International Publishing, LLC, 2004, 187-193
Fleming J.S.
Design and performance of different gamma camera systems for PET
Hillel P, Basics of Gamma Camera Positron Emission Tomogrpahy, York, Institute of Physics and Engineering in Medicine, 2004, 16-33
Williams J., Kemp, P.M., Hoffmann, S.M.A., Langford, J., Huggett, S.M.
Evaluation of a motion correction algorithm for brain imaging using clinical data
Nuclear Medicine Communications, 25, 2004, 411
Pitcairn, G., Kalirai, C., Joyson, A., Newman, S., Fleming J.
Development of a standard method for quantifying regional lung deposition from SPECT and relating the data to airway anatomy.
Dalby, R.N. Byron P.R, Peart J, Suman,J.D., Farr, S.J., Respiratory Drug Delivery IX, River Grove Illinois, Davis Healthcare International Publishing, LLC, 2004, 621-624
Nuclear Medicine Communications, 24, 2003, 467 (Abstract)
Bolt L, Fleming JS, Hoffmann SMW, Kemp PM, Costa DC
Quantifying DaTSCAN images: how automation reduces operator variability
Nuclear Medicine Communications, 24, 2003, 445 (abstract)
Kemp, P. M., Holmes, C., Hoffmann, S.M.A., Bolt, L. Fleming, J.S., Ward, A., Thom, J., Zivanovic, M.A., Wilkinson, D.
A randomised double-blind placebo-controlled study to assess the efects of cholinergic theray in Alzheimer’s disease as demonstrated by imaging the post-synaptic muscarinic receptor.
European Journal of Nuclear Medicine, 30, 2003, S223
Kemp, P.M., Hoffmann, S.M.A., Bolt, L. Holmes, R.B. Fleming, J.S.
HMPAO SPECT scan differences in early and late onset Alzheimer’s disease as assessed by statistical parametric mapping Nuclear Medicine Communications, 24, 2003, 444
Misson, S.C., Fleming, J.S., Hoffmann, S.M.A., Nagaraj, N.
UK audit of single photon emission computed tomography reconstrcution software using software generated phantoms.
Nuclear Medicine Communications, 23, 2002, 483-491
Martonen, T.B., Schroeter, J.D., Zhang, Z., Hwang, D., Fleming, J.S.
Targeted delivery of inhaled proteins.
In Dalby, R.N., Byron, P.R., Peart, J., Farr, S.J., Respiratory Drug Delivery VIII Program and Proceedings Volume II, Godalming, Surrey, Davis Horwood International, 2002, 723-725
Fleming J.S., Kemp, P.M., Bolt, L., Goatman, K.A.
Measurement of cerebral perfusion volume and Tc-99m HMPAO uptake using SPECT in controls and patients with Alzheimer’s disease.
Nuclear Medicine Communications, 23, 2002, 1057-1064
Bolt l, Fleming JS, Kemp PM
Quantifying DaTSCAN images: is the technique robust an duseful?
Nuclear Medicine Communications, 23, 2002, 286 (Abstract)
UK audit of quantitative nuclear medicine renography.
European Journal of Nuclear Medicine., 27, 2000, 990
Sauret, V, Fleming, J.S., Bailey, A.G.
The use of multimodality imaging to study the pulmonary deposition of inhaled aerosol.
Allen, R., Fleming, J.S., and Petley, G.W, Proceedings of the Sixth Annual National Conference of the Institute of Physics and Engineering in Medicine, York, IPEM, 2000, 56
Factors affecting quantitative parameters obtained from renography.
Nuclear Medicine Communications, 21, 2000, 385
Goatman, K.A., Fleming, J.S., Bolt, L. Kemp, P.M..
An automatic method for measuring functional brain volume using SPECT imaging.
Proceedings of Medical Image Understanding and Analysis MIUA2000, London, Communications in Print plc, 2000, 157-160
Walker, P.S., Pettersson, Conway, J.H., Fleming, J.S., Bondesson, E., Borgstrom, L.
Pre-clinical validation of a terbutaline sulphate labelling procedure.
Dalby, R.N., Byron, P.R., Farr, S.J., Peart, J, Respiratory Drug Delivery VII Program and Proceedings Volume II, Raleigh, NC, Serentec Press, 2000, 531-534
Functional brain volume from HMPAO SPET: reproducibility and application in Alzheimer’s disease.
Nuclear Medicine Communications, 21, 2000, 382
Sauret, V, Fleming, J.S., Bailey, A.G.
3D realistic anatomical model of the central airways to improve aerosol deposition predictions and medical image analysis. Dalby, R.N., Byron, P.R., Farr, S.J., Peart, J.I, Respiratory Drug Delivery VII Program and Proceedings Volume I, Raleigh, NC, Serentec Press, 2000, 527-530
The influence of pulmonary clearance on quantitative three dimensional radionuclide imaging of inhaled aerosol deposition. Dalby, R.N., Byron, P.R., Farr, S.J., Peart, J., Respiratory Drug Delivery VII Program and Proceedings Volume II, Raleigh, NC, Serentec Press, 2000, 523-526
Conway, J.H., Walker, P.S., Fleming, J.S., Bondesson, E., Borgstrom, L. Holgate, S.T.
Three-dimensional description of the deposition of inhaled terbutaline sulphate administered via Turbuhaler.
Dalby, R.N., Byron, P.R., Farr, S.J., Peart, J., Respiratory Drug Delivery VII Program and Proceedings Volume II, Raleigh, NC, Serentec Press, 2000, 607-610
Tristam, M., Fleming, J.S., Lewington, V.J., Zivanovic, M.A., Wilson, L.M.
Advances in targeted radionuclides therapies.
Allen, R., Fleming, J.S., and Petley, G.W, Proceedings of the Sixth Annual National Conference of the Institute of Physics and Engineering in Medicine, York, IPEM, 2000, 57
UK audit and analysis of quantitative parameters obtained from nuclear medicine renography.
Image Processing: Implementation of Research into Clinical Application: Virtual Meeting., IPEM web site (www.ipem.org.uk), 1999,
Fleming, J.S., Kemp, P.M., and Bolt, L.B.
A technique for manual definition of an irregular volume of interest in single photon emission computed tomography.
Physics in Medicine and Biology, 44, 1999, N15-N20
Martonen, T.B., Zhang, Z., Yu, G., Musante, C., Hwang, D., Segal, R., and Fleming, J.S
Targeted delivery of inhaled proteins.
Journal of Aerosol Medicine, 12, 1999, 133
Fleming, J.S., Kemp, P.M.
A comparison of deconvolution and the Patlak-Rutland plot in renography analysis.
Nuclear Medicine Communications, 20, 1999, 469
Fleming, J.S.
Accuracy of estimation of glomerular filtration rate from renography.
Journal of Nuclear Medicine, 40, 1999, 1968-1969
Sauret, V., Goatman, K.A., Fleming, J.S. and Bailey, A.G.
Semi-automated tabulation of the 3D topology and morphology of branching networks using CT: application to the airway tree. Physics in Medicine and Biology.
Physics in Medicine and Biology, 44, 1999, 1625-1638
Fleming, J.S., and Kemp, P.M.
A comparison of deconvolution and the Patlak-Rutland plot in renography analysis.
Evaluation of the accuracy and precision of lung aerosol deposition measurements from planar imaging using simulation., Physics in Medicine and Biology, 43, 1998, 2423-2429
Fleming, J.S., Alaamer, A.S.
A rule based method for context sensitive threshold segmentation in SPECT using simulation.
Physics in Medicine and Biology, 43, 1998, 2309-2323
How reproducible is SPECT and MRI in the assessment of deposition of nebulised aerosols? American Journal of Respiratory and Critical Care Medicine, 1997
American Journal of Respiratory and Critical Care Medicine, 1997,
The use of combined SPECT and MRI to assess the effect of airway obstruction on aerosol deposition.
American Journal of Respiratory and Critical Care Medicine., 153, 1996, A482
Hashish, A.H., Fleming, J.S., Conway, J.H., Halson, P., Moore, E., Williams, T.J., Bailey, A.G., Nassim, M.A., Holgate, S.T. Comparison of 3D SPECT data with model predictions of aerosol deposition in the lung.
Journal of Aerosol Medicine, 9, 1996, 450
Fleming, J.S., Alaamer, A.S
The influence of collimator characteristics on quantification in single photon emission computed tomography.
Journal of Nuclear Medicine, 37, 1996, 1832-1836
Patankar, R., Ozmen, M.M., Aldous, A., Khader, Z., Fleming, J.S., Johnson, C.D.,
Standardisation of a technique for BrIDA cholescintigraphy.
Nuclear Medicine Communications, 17, 1996, 724-728
Fleming, J.S.
Evaluation of a technique for simulation of gamma camera images.
Physics in Medicine and Biology, 41, 1996, 1855-1861
Potential of SeHCAT retention as an indicator of terminal ileal involvement in inflammatory bowel disease.
European Journal of Nuclear Medicine, 10, 1995, 528-530
Martonen, T.B., Yang, Y., Hwang, D., Fleming, J.S.
Computer simulations of human lung structures for medical applications.
Computers in Medicine and Biology, 25, 1995, 431-446
Conway, J.H., Halson, P., Moore, E., Hashish, A.H., Nassim, M., Fleming, J.S., Holgate, S.T.
Multi-modality imaging: the use of single photon emission tomography and magnetic resonance imaging to assess regional intra-pulmonary deposition of nebulised aerosols.
A new method of quantification of the pulmonary regional distribution of aerosols using combined CT and SPECT and its application to nedocromil sodium administered by metered dose inhaler.
British Journal of Radiology, 67, 1994, 46-53
Perring, S., Hind, R., Fleming, J.S., Birch, S., Batty, V., Taylor, I.
Dosimetric assessment of radiolabelled lipiodol as a potential therapeutic agent in colorectal liver metastases using combined CT and SPECT.
Nuclear Medicine Communications, 15, 1994, 34-38
Alaamer, A.S., Fleming, J.S., Perring, S.
Evaluation of the factors affecting the accuracy and precision of a technique for quantification of volume and activity in SPECT.
Nuclear Medicine Communications, 15, 1994, 758-771
Fleming, J.S., Simpson, D.E.
A technique for simulation of the point spread function of a gamma camera.
Physics in Medicine and Biology, 39, 1994, 1457-1473
Martonen, T.B., Yang, Y., Hwang, D., Fleming., J.S.
Mapping the human lung using delaunay tesselation.
Computers in Biomedical Research, 27, 1994, 245-262
Humidification as an adjunct to chest physiotherapy in aiding tracheo-bronchial clearance in patients with bronchiectasis. Respiratory Medicine, 86, 1992, 109-114
Krypton-81m equilibrium radionuclide ventriculography for the assessment of right heart function.
European Journal of Nuclear Medicine, 16, 1990, 89-95
Summers, Q.A., Hollingsworth, A., Clark, A.R., Fleming, J.S., Holgate, S.T.
The preparation of a radio-labelled aerosol of nedocromil sodium for administration by metered dose inhaler that accurately preserves the particle size distribution of the drug.
Measurement of glomerular filtration rate with Tc-99m DTPA : comparison of plasma clearance techniques. Reply to letter. Journal of Nuclear Medicine, 29, 1988, 1153-1154
Jackson PC
The equipment involved in radionuclide imaging
Thomas WEG and Davies ER, Nuclear Medicine: Applications to Surgery, Tunbridge Wells, Kent, Castle House Publications, 1988, 17-37
Practical experience of image transfer form nuclear medicine, x-ray CT and video sources to a VAX computer
Tofts, P.S., Cranage, R.W, Networks and Image Handling: Institute of Physical Sciences in Medicine Report 52, York, Institute of Physical Sciences in Medicine, 1987, 63-69
Pitcher EM, Jackson PC, Key H, Stevens PH
Technical factors involved in the superimposition of digital images
Tofts PS & Cranage RA, Networks & Image Handling, York, Institute of Physical Sciences in Medicine, 1987, 70-76
Jackson PC
A glimpse at the ACR-NEMA digital imaging and communications standard
Tofts PS & Cranage RA, Networks & Image Handling, York, Institute of Physical Sciences in Medicine, 1987, 35-43
Does radiolabelled diphosphonate retention reflect bone metabolism in the elderly.
Age and Ageing, 15, 1986, 164-168
Fleming, J.S., Hames, T.K., Smallwood, J.
A comparison of impedance and water displacement plethysmography in the assessment of volume change in the forearm. Medical and Biological Engineering and Computing, 24, 1986, 375-378
Hutton CW, Higgs ER, Jackson PC, Watt I, Diepee PA
Tc-HMDP bone scanning in generalised osteoarthritis.
Alterations in liver blood flow and reticulo-endothelial function in progressive cirrhosis in the rat. Journal of Nuclear Medicine Journal of Nuclear Medicine, 27, 1986, 1751-1754
Channer KS, Jackson PC, Virgee JP
The value of eosophageal transit tests in the investigation of patients with chest pain.
Abst Br J Radiol, 59, 1986, 805-806
Jackson PC
Radionuclide Imaging: Theory and Practice
London, Farrand Press, 1986, ISBN 1-85083-003-7,
Murphy, P., Alexander, P., Kirkham, N., Fleming, J.S., Taylor, I.
The pattern of spread of blood borne tumour.
British Journal of Surgery, 73, 1986, 829-834
Hutton CW, Higgs ER, Jackson PC, Watt I, Dieppe PA
Tc-HMDP bone scanning in generalised osteoarthritis I: comparison of the standard radiographs and four hour bone scan image of the hand.
Ann Rheum Dis, 45, 1986, 617-621
Qamar MA, Mountford RA, Jackson PC, Davies ER, Read AE.
Gastric emptying and superiormesenteric artery (SMA) blood flow following a liquid meal.
Abst Br J Radiol, 58, 1985, 811
Davies ER, Davies JO, Jackson PC, Howe K, Pitcher EM, Sadowski CS, Stirrat GM, Sunderland CA
123 I-NDOG2 anti-placental alkaline phosphatase imaging of ovarian tumours.
Abst Brit J Can, 52, 1985, 649
Jackson PC, Davies Er, Davies JO, Pitcher EM, Sadowski C, Staddon GE, Stirrat GM, Sunderland CA
Radionuclide imaging of ovarian tumour with a radiolabelled (123I) monoclonal antibody.
Abst Phys Med Biol, 30, 1985, 95
Fleming, J.S.
A technique for motion correction in dynamic scintigraphy.
European Journal of Nuclear Medicine, 9, 1985, 397-402
Davies JO, Davies ER, Howe K, Jackson PC, Pitcher EM, Randle B, Sadowski C, Stirrat GM, Sunderland CA
Practical applications of monoclonal antibody (NDOG2) against placental alkaline phosphatase in ovarian cancer.
J Royal Soc Med, 78, 1985, 899-905
Jackson PC, Jones M, Brimble CE, Hart J
The reduction of inter- and intra-observer variability for defining regions of interest in nuclear medicine.
Eur J Nucl Med, 11, 1985, 186-189
Channer KS, Jackson PC, O'Brien IO, Corrall RJM, Coles DR, Davies Rhys E, Virgee JP
Oesophageal function in diabetes mellitus and its association with autonomic neuropathy.
Diabetic Medicine, 2, 1985, 378-382
Jackson PC, Pitcher EM, Davies JO, Davies ER, Sadowski CS, Staddon GE, Stirrat GM, Sunderland CA.
Radionuclide imaging ovarian tumours with a radiolabelled (I-123) monoclonal antibody (NDOG2).
Eur J Nucl Med, 11, 1985, 22-28
Davies JO, Davies ER, Howe K, Jackson PC, Pitcher EM, Sadowski CS, Stirrat GM, Sunderland CA.
Raionuclide imaging of ovarian tumours with (I-123) labelled monoclonal antibody (NDOG2) directed against placental alkaline phosphatase.
Br J Obst Gynae, 92, 1985, 227-286
Fleming, J.S., Goddard, B.A., Ackery, D.M
Contralateral correction in lateral lung radionuclide imaging in phantom and clinical studies.
European Journal of Nuclear Medicine, 7, 1985, 158-161
Murphy, P., Fleming, J.S., Taylor, I., Alexander, P.
The efficacy of trapping of blood borne cancer cells by the organ of first encounter in experimental rat tumours.
Hellman, K., Eccles, S.A., Treatment of metastasis : problems and prospects, London, Taylor and Francis, 1985,
McLaren, M.I., Fleming, J.S., Walmsley, B.H., Karran, S.J., Taylor. I.
Dynamic liver scanning in cirrhosis.
British Journal of Surgery, 72, 1985, 394-396
Lewis, R.A., Fleming, J.S
Fractional deposition from a jet nebuliser : how it differs from a metered dose inhaler.
British Journal of Diseases of the Chest, 79, 1985, 361-367
Nakielny RA, Thomas WEG, Jackson PC, Jones M, Davies ER
Radionuclide evaluation of scrotal disease
Clin Rad, 35, 1984, 125-129
Fleming, J.S., Goddard, B.A.
Evaluation of techniques for stationary coded aperture three-dimensional imaging in nuclear medicine.
Nuclear Instruments and Methods in Physical Research, 221, 1984, 242-246
In-vivo measurement of liver perfusion in the normal and partially hepatectomised rat using Tc-99m sulphur colloid.
Journal of Nuclear Medicine, 20, 1979, 26-31
Fleming, J.S.
Technique for contralateral subtraction in lateral lung radionuclide imaging.
Medical and Biological Engineering and Computing, 17, 1979, 751-756
Fleming, J.S.
The manufacture and properties of two dimensional position sensitive orthogonal electrode silicon surface barrier detectors. Nuclear Instruments and Methods, 150, 1978, 417-425
Fleming, J.S.
Measurement of Hippuran plasma clearance using a gamma camera.
Physics in Medicine and Biology, 22, 1977, 526-530