1 Novel mouse model of encephalocele: post-neurulation origin and relationship to open neural tube defects Ana Rolo *, Gabriel L. Galea, Dawn Savery, Nicholas D. E. Greene, Andrew J. Copp * Newlife Birth Defects Research Centre, GOS Institute of Child Health, University College London, 30 Guilford Street, London WC1N 1EH, UK * Corresponding authors: [email protected] and [email protected] Running title: Novel mouse model of encephalocele not certified by peer review) is the author/funder. All rights reserved. No reuse allowed without permission. The copyright holder for this preprint (which was this version posted May 24, 2019. ; https://doi.org/10.1101/649624 doi: bioRxiv preprint