Noninvasive Imaging Predicts Failure Load of the Spine with Simulated Osteolytic Defects*† by Kelli M. Whealan, S. Daniel Kwak, John R. Tedrow, Kaoru Inoue,

Noninvasive Imaging Predicts Failure Load of the Spine with Simulated Osteolytic Defects*†

by Kelli M. Whealan, S. Daniel Kwak, John R. Tedrow, Kaoru Inoue, and Brian D. Snyder

J Bone Joint Surg AmVolume 82(9):1240-1240

September 1, 2000

©2000 by The Journal of Bone and Joint Surgery, Inc.

Computed tomography images showing the locations of the simulated defects.

Kelli M. Whealan et al. J Bone Joint Surg Am 2000;82:1240

©2000 by The Journal of Bone and Joint Surgery, Inc.

Pixel-mapping algorithms. x¯, y¯ are the coordinates of the modulus-weighted centroid, and da represents a single pixel with dimensions determined by the resolution of the computed

tomography image.

Kelli M. Whealan et al. J Bone Joint Surg Am 2000;82:1240

©2000 by The Journal of Bone and Joint Surgery, Inc.

Dual-energy x-ray absorptiometry cross-sectional attenuation profile.

Kelli M. Whealan et al. J Bone Joint Surg Am 2000;82:1240

©2000 by The Journal of Bone and Joint Surgery, Inc.

Illustration of the hydraulic spine testing system39.

Kelli M. Whealan et al. J Bone Joint Surg Am 2000;82:1240

©2000 by The Journal of Bone and Joint Surgery, Inc.

The slope of the regression line for the correlation between the quantitative computed tomography (QCT)-predicted and the measured failure loads (Fz) was dependent on defect

location (p = 0.023).

Kelli M. Whealan et al. J Bone Joint Surg Am 2000;82:1240

©2000 by The Journal of Bone and Joint Surgery, Inc.

Concordance of predicted failure load by quantitative computed tomography (QCT) and measured failure load (Fz) about the y = x line (rc = 0.74).

Kelli M. Whealan et al. J Bone Joint Surg Am 2000;82:1240

©2000 by The Journal of Bone and Joint Surgery, Inc.