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NIGMS Award: 1U54GM104944-01A1 Mountain West Research Consortium Clinical Translational Research – Infrastructure Network The Mountain West CTR-IN Robert D. Langer, MD, MPH Principal Investigator Research Professor of Allied Health Sciences, UNLV Associate Dean for Clinical and Translational Research and Professor of Family Medicine-Las Vegas, UNSOM
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NIGMS Award: 1U54GM104944-01A1 Mountain West Research Consortium Clinical Translational Research – Infrastructure Network The Mountain West CTR-IN Robert.

Dec 17, 2015

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Page 1: NIGMS Award: 1U54GM104944-01A1 Mountain West Research Consortium Clinical Translational Research – Infrastructure Network The Mountain West CTR-IN Robert.

NIGMS Award: 1U54GM104944-01A1

Mountain West Research ConsortiumClinical Translational Research –

Infrastructure Network

The Mountain West CTR-IN

Robert D. Langer, MD, MPHPrincipal Investigator

Research Professor of Allied Health Sciences, UNLVAssociate Dean for Clinical and Translational Research and Professor

of Family Medicine-Las Vegas, UNSOM

Page 2: NIGMS Award: 1U54GM104944-01A1 Mountain West Research Consortium Clinical Translational Research – Infrastructure Network The Mountain West CTR-IN Robert.

What is it?

$20 million 5 year NIH Grant under the IDeA Program

Involving 13 universities across the 7 IDeA states in the Mountain West Research Consortium

Page 3: NIGMS Award: 1U54GM104944-01A1 Mountain West Research Consortium Clinical Translational Research – Infrastructure Network The Mountain West CTR-IN Robert.

What are the 7 Mountain West states?

Alaska

Hawaii

Idaho

Montana

Nevada

New Mexico

Wyoming

Page 4: NIGMS Award: 1U54GM104944-01A1 Mountain West Research Consortium Clinical Translational Research – Infrastructure Network The Mountain West CTR-IN Robert.

Support: to foster Clinical and Translational Research

(CTR) according to NIH Definitions

for Core Resources to facilitate the development of researchers moving into CTR

BOOTSTRAP CTR ACROSS THE MOUNTAIN WEST

Page 5: NIGMS Award: 1U54GM104944-01A1 Mountain West Research Consortium Clinical Translational Research – Infrastructure Network The Mountain West CTR-IN Robert.

“a rising tide that … … lifts all ships.”

We will sink or swim based on the increase in “R-level” translational

and clinical research that we achieve across the region over

the next 4 years

Page 6: NIGMS Award: 1U54GM104944-01A1 Mountain West Research Consortium Clinical Translational Research – Infrastructure Network The Mountain West CTR-IN Robert.

Who is in it?

Page 7: NIGMS Award: 1U54GM104944-01A1 Mountain West Research Consortium Clinical Translational Research – Infrastructure Network The Mountain West CTR-IN Robert.

What will it do?

Provide pilot grants of $40,000-$75,000/yr

Support Mini-Sabbatical and Visiting Scholar awards to build collaborations

Provide infrastructure and services through Key Component Activities

Page 8: NIGMS Award: 1U54GM104944-01A1 Mountain West Research Consortium Clinical Translational Research – Infrastructure Network The Mountain West CTR-IN Robert.

Funding preference

Promising Early Career or New Investigators developing clinical or translational research programs

Established Investigators moving from bench to translational or clinical

Projects focused on health issues relevant to the region, including those in rural and vulnerable populations

Page 9: NIGMS Award: 1U54GM104944-01A1 Mountain West Research Consortium Clinical Translational Research – Infrastructure Network The Mountain West CTR-IN Robert.

What will it do?

Use an NIH-style approach to applications and funding

Model the processes that clinical and translational investigators need to master to compete successfully for NIH support

Page 10: NIGMS Award: 1U54GM104944-01A1 Mountain West Research Consortium Clinical Translational Research – Infrastructure Network The Mountain West CTR-IN Robert.

Key Component Activities (KCAs)

Education, Mentoring & Career Development KCA

Study Design & Biostatistics KCA

Pilot Grant KCA

Administrative KCA, including editorial support, award management, Annual Meeting

Page 11: NIGMS Award: 1U54GM104944-01A1 Mountain West Research Consortium Clinical Translational Research – Infrastructure Network The Mountain West CTR-IN Robert.

EducationMentoring

Study DesignBiostat

Annual Meeting

ALL AVAILABLE regardless of whether you’ve received a

competitive award from the CTR-IN

Page 12: NIGMS Award: 1U54GM104944-01A1 Mountain West Research Consortium Clinical Translational Research – Infrastructure Network The Mountain West CTR-IN Robert.

What will it do?

Hold an Annual Meeting to share science, motivate, build collaborations, & conduct study business that will: rotate across the 13 partner institutions feature an annual research theme relevant to

health in the regionbring together supported investigators, interested

researchers from the region, key administrators from partners, external scientists, the regional biostat team, and senior project staff

First Annual Meeting at UNLV June 23 – 25, 2014

free registration, hotel rate ~ $100/night

Page 13: NIGMS Award: 1U54GM104944-01A1 Mountain West Research Consortium Clinical Translational Research – Infrastructure Network The Mountain West CTR-IN Robert.

What’s the current status?

Round 1 Pilot Grants: 24 applications, 6 awarded

Round 1A Pilot Grants: 63 applications, 14 awarded

Page 14: NIGMS Award: 1U54GM104944-01A1 Mountain West Research Consortium Clinical Translational Research – Infrastructure Network The Mountain West CTR-IN Robert.

Year 1 Pilot Grants

Round 1 Round 1A Total

Boise State 0 3 3

Idaho State 0 1 1

Montana State 2 1 3

New Mexico State 0 1 1

U Alaska - Anchorage 0 1 1

U Alaska - Fairbanks 0 1 1

U Idaho 0 1 1

U Montana 2 0 2

U Nevada Las Vegas 1 3 4

U Nevada Reno 1 1 2

U Wyoming 0 1 1

6 14 20

Page 15: NIGMS Award: 1U54GM104944-01A1 Mountain West Research Consortium Clinical Translational Research – Infrastructure Network The Mountain West CTR-IN Robert.

What’s the current status?

Round 2 Pilot Grant RFA for 7/1/14 – 6/30/15:Letters of Intent with Abstacts were due 3/7/14

122 LOIs with Abstracts received

Invitations to submit 3/14/14Applications due 4/25/14Awards announced at Annual Meeting 6/25/14Earliest start date 7/1/14

All information at: ctrin.unlv.edu

Page 16: NIGMS Award: 1U54GM104944-01A1 Mountain West Research Consortium Clinical Translational Research – Infrastructure Network The Mountain West CTR-IN Robert.

U. Alaska Anchorage 8

U. Alaska Fairbanks 5

Boise State U. 3

Idaho State U. 14

U. Idaho 8

Montana State U. 7

U. Montana 5

New Mexico State U. 9

UNR 23

UNLV 30

U. Wyoming 10

Letters of Intent for Year 2 Pilot Grants

Total 122

Page 17: NIGMS Award: 1U54GM104944-01A1 Mountain West Research Consortium Clinical Translational Research – Infrastructure Network The Mountain West CTR-IN Robert.

Visiting Scholars

Call still open

Funds must be expended by 06/30/14

4 applications to-date, all awardedU Montana – to PG Awardee

UNLV – to PG Awardee

U Hawaii

UNLV

Page 18: NIGMS Award: 1U54GM104944-01A1 Mountain West Research Consortium Clinical Translational Research – Infrastructure Network The Mountain West CTR-IN Robert.

PEOPLE!

Page 19: NIGMS Award: 1U54GM104944-01A1 Mountain West Research Consortium Clinical Translational Research – Infrastructure Network The Mountain West CTR-IN Robert.

Your First Call …

Your Local Conciergehttp://ctrin.unlv.edu/?page_id=447

Page 20: NIGMS Award: 1U54GM104944-01A1 Mountain West Research Consortium Clinical Translational Research – Infrastructure Network The Mountain West CTR-IN Robert.

Senior Leadership

Administrative Core

Bob Langer, UNLV, PI

Jim Kenyon, UNR, Proj Coord.

Carl Reiber, UNLV, Assoc. Dir.

John Foreyt, UNSOM, Eval. Dir.

Pilot Grants

Curtis Noonan, UMT, Director

Bill Shuttleworth, UNM, Assoc. Dir.

Education & Mentoring

Jillian Inouye, UNLV, Directorer

Bruce Shiramizu, UH, Mentoring

Pope Moseley, UNM, Mentoring

Merle Kataoki-Yahiro, UH, Educ

Craig Molgaard, UMT, Educ

Design, Epidemiology, Biostat

Pope Moseley, Director

UNM CTSA: Richard Larson

Page 21: NIGMS Award: 1U54GM104944-01A1 Mountain West Research Consortium Clinical Translational Research – Infrastructure Network The Mountain West CTR-IN Robert.

website

ctrin.unlv.edu

NIGMS Award: 1U54GM104944-01A1

Page 22: NIGMS Award: 1U54GM104944-01A1 Mountain West Research Consortium Clinical Translational Research – Infrastructure Network The Mountain West CTR-IN Robert.

Admin KCARobert Langer, MD, MPH, KCA Director

Carl Reiber, PhD, Assoc. DirectorJim Kenyon, PhD, Project Coordinator

CRDEB KCAPope Moseley, MD, KCA Director

Pilot Grant KCACurtis Noonan, PhD, KCA Director

AFFILIATION COLOR CODEUNLV

UNSOMU. New Mexico

U. MontanaNIH

Other Institutions

Internal Advisory Committee Carolyn Yucha, PhD, Co-Chair

Thomas Schwenk, MD, Co-ChairVPRs of all 13 Partner Universities

Robert Langer, MD, MPH, PI, ex oficioJim Kenyon, PhD, Project Coordinator, ex oficio

External Advisory Committee6 to 10 External Scientists

from outside the 7 state region

Steering CommitteeRobert Langer, MD, MPH, Principal InvestigatorJim Kenyon, PhD, Project Coordinator, Partners

John Foreyt, PhD, Project Coordinator, T&ERafael Gorospe, MD, PhD, Project Officer

Maria Canto, DDS, MS, MPH, Project Scientist

Executive CommitteePI

2 Project Coordinators3 [4 with PI] KCA DirectorsAssoc. Director, Admin KCA

Lead LiaisonCTSC Coordinator

Principal InvestigatorRobert Langer, MD, MPH

Educ & Mentoring KCAJillian Inouye, PhD, KCA Director

Mentoring Unit Education Unit

Regional Biostatistician Network

Mountain West CTR-IN Organizational StructureGovernance and Membership

UNM CTSCRichard Larson, MD, Coord.

Track & Eval UnitJohn Foreyt, PhD,

Project Coordinator

ConciergesJill Zimbelman, Lead Concierge

Regional Network