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NIDM-Results: a model to share brain mapping statistical results

Apr 15, 2017

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Camille Maumet
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Page 1: NIDM-Results: a model to share brain mapping statistical results
Page 2: NIDM-Results: a model to share brain mapping statistical results
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Page 4: NIDM-Results: a model to share brain mapping statistical results

Analysis

Pre-processing

Publication

Raw data

Pre-processed data

Results

Publication

Page 5: NIDM-Results: a model to share brain mapping statistical results

Publicly available

data

Analysis

Pre-processing

Publication

Raw data

Pre-processed data

Results

Publication

Page 6: NIDM-Results: a model to share brain mapping statistical results

Publicly available

data

Analysis

Pre-processing

Publication

Raw data

Pre-processed data

Results

Publication

< 5% of data shared in public repositoriesB

UT

Page 7: NIDM-Results: a model to share brain mapping statistical results

Analysis

Pre-processing

Publication

Raw data

Pre-processed data

Results

Publication

Page 8: NIDM-Results: a model to share brain mapping statistical results

Analysis

Pre-processing

Publication

Raw data

Pre-processed data

Results

Publication

Page 9: NIDM-Results: a model to share brain mapping statistical results

Analysis

Pre-processing

Publication

Raw data

Pre-processed data

Results

Publication

Page 10: NIDM-Results: a model to share brain mapping statistical results

Publication

Peak locationsFigure

(selected slices)Thresholded

statistics

Analysis

Pre-processing

Publication

Raw data

Pre-processed data

Results

Publication

Page 11: NIDM-Results: a model to share brain mapping statistical results

Publication

Peak locationsFigure

(selected slices)Thresholded

statistics

Analysis

Pre-processing

Publication

Raw data

Pre-processed data

Results

Publication

❌❌❌

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Page 13: NIDM-Results: a model to share brain mapping statistical results

Analysis

Pre-processing

Raw data

Pre-processed data

Results

Study 1

Analysis

Pre-processing

Raw data

Pre-processed data

Results

Study 2

Analysis

Pre-processing

Raw data

Pre-processed data

Results

Study n...

Meta-analysisResults

Page 14: NIDM-Results: a model to share brain mapping statistical results
Page 15: NIDM-Results: a model to share brain mapping statistical results

Coordinate- or Image-Based?Acquisition Analysis

Experiment Raw data Results

Acquisition Analysis

Experiment Raw data Results

Publication

Publication

Paper

Paper

Page 16: NIDM-Results: a model to share brain mapping statistical results

Coordinate- or Image-Based?Acquisition Analysis

Experiment Raw data Results

Acquisition Analysis

Experiment Raw data Results

Publication

Publication

Paper

Paper

Coordinate-based meta-analysis

Coordinate-based meta-analysis

Page 17: NIDM-Results: a model to share brain mapping statistical results

Image-based meta-analysis

Shared results

Full results reporting

Coordinate- or Image-Based?Acquisition Analysis

Experiment Raw data Results

Acquisition Analysis

Experiment Raw data Results

Publication

Publication

Paper

Paper

Coordinate-based meta-analysis

Coordinate-based meta-analysis Image-based meta-analysis

Page 18: NIDM-Results: a model to share brain mapping statistical results
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Page 23: NIDM-Results: a model to share brain mapping statistical results

Standard error map

Statistic mapE.g. Z-map

Contrast map Design matrix(png and csv)

NIDM-Resultsgraph

.nidm

.zip

Page 24: NIDM-Results: a model to share brain mapping statistical results

NIDM-Results

http://nidm.nidash.org

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http://nidm.nidash.org/specs/nidm-results.html

Definition

Attributes

Examples

Page 26: NIDM-Results: a model to share brain mapping statistical results

Harmonisation across software

• Model of the error– Prob. distribution:– Variance:

– Dependence:heterogeneous

Independent noise

homogeneous

Compound Symmetry

Serially correlated

Arbitrarily correlated

Gaussian Non-Parametric …

global

local

regularized

Page 27: NIDM-Results: a model to share brain mapping statistical results

Error models: SPM, FSL and AFNIGroup levelSubject level

Page 28: NIDM-Results: a model to share brain mapping statistical results
Page 30: NIDM-Results: a model to share brain mapping statistical results

$ nidmfsl ds107.gfeat -g Control 49

pip

https://github.com/incf-nidash/nidmresults-fslhttp://fsl.fmrib.ox.ac.uk

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http://neurovault.org

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http://neurovault.org

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http://neurovault.org

Page 34: NIDM-Results: a model to share brain mapping statistical results

Coordinate-based meta-analysis Image-based meta-analysis

Scripts available at http://github.com/incf-nidash/nidmresults-paper

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Thank you! To all the INCF NIDASH task force members.

This work is supported by the

Warwick neurodata sharing Tom Nichols, Alex Bowring, Ruth Pauli, Peter Williams, Tom Maullin-Sapey.

NIDM working group Tibor Auer, Samir Das, Fariba Fana, Guillaume Flandin, Satra Ghosh, Tristan Glatard, Chris Gorgolewski, Karl Helmer, David Keator, Nolan Nichols, Jean-Baptiste Poline, Vanessa Sochat, Jason Steffener, Jessica Turner.

SPM Guillaume Flandin.FSL Mark Jenkinson, Matthew Webster, Paul McCarthy, Eugene Duff, FSL Steve Smith.AFNI Gang Chen, Richard Reynolds, Ziad Saad, Robert Cox.

Meta-analysis dataset Tracey group at FMRIB.

Page 38: NIDM-Results: a model to share brain mapping statistical results

Q & A

Maumet, C. et al. Sharing brain mapping statistical results with the neuroimaging data model. Sci. Data 3:160102 doi: 10.1038/sdata.2016.102 (2016).

https://github.com/incf-nidash http://nidm.nidash.org