NIDCR - Sponsored Practice- Based Research Networks (PBRN) Designed to gather “real-world” evidence for the prevention and treatment of oral diseases Donald J. DeNucci, DDS, MS Program Director Practice-Based Research Networks National Institute of Dental and Craniofacial Research
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NIDCR - Sponsored Practice-Based Research Networks (PBRN)
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NIDCR - Sponsored Practice-Based Research Networks (PBRN)
Designed to gather “real-world” evidence for the prevention and treatment of oral diseases
Donald J. DeNucci, DDS, MSProgram DirectorPractice-Based Research NetworksNational Institute of Dental and Craniofacial Research
Dental Practice-Based Research Networks - Purpose
Answer questions facing general dental practitioners in the routine care of their patients
Strengthen knowledge base for making clinical decisions
• Observational studies
• Clinical trials
• Establish/use a flexible, adaptable electronic network/platform
for connectivity, data sharing, & communication within and
between dental and medical networks
Dental Practice-Based Research Networks-Objectives Stimulate research proposals from practicing dentists and
Networks collaborating on a study of the risk factors for osteonecrosis of the jaw in relation to a variety of factors including use of bisphosphonate drugs
PBRN Collaborative Research Activities Year Four
Networks are collaborating with the NIH National Cancer Institute’s Center for Bioinformatics in defining common data elements and establishing a common data vocabulary repository
PBRN Collaborative Research Activities Year Four
Networks collaboratively established a Practice Impact Research Group (PIRG)
Designed to measure and assess the impact of practice-based research on translation and ultimately changes in clinical practice leading to improvements in patient care and oral health
PBRN Collaborative Research Activities Year Four
Collaborating with the VA Dental Practice-based Research Network (VADER)
VADER comprised of over 600 dental professional using one integrated electronic medical and dental record
PBRN Collaborative Research Activities Year Four
VADER ONJ Study in Veterans
VADER Cranial Implant Study
PBRN Research ActivitiesPotential for collaboration with medicine PEARL: Analgesic prescribing practices of
dentists, drugs impacting oral health (xerostomia, gingival hyperplasia), impact of periodontal therapy on diabetes and cardiovascular disease
DPBRN: Infection after surgical procedures in diabetic patients, glycemic screening in dental offices, tobacco cessation
PRECEDENT: Computer assisted program for needle phobia, anxiety management
General Dental Practice-Based Research Networks
NYU PEARL NetworkUniversities of Alabama / Florida DPBRN Network Permanente Dental Associates Health Partners Georgia
Mississippi Scandinavia
Universities of Washington / OregonNW PRECEDENT Network
TransPBRN CONDOR Network comprisingall three networks
NIDCR Funded Oral Health Disparities Program Established Community Networks Configured to Conduct Interventional Trials
University of WashingtonUniversity of FloridaUniversity of California - San FranciscoUniversity of Colorado - DenverBoston University*University of Michigan
*Pilot Program in Detroit inner city
Donald J. DeNucci, D.D.S., M.S.Program DirectorPractice Based Research NetworksCenter for Clinical ResearchNational Institute of Dental and Craniofacial Research6701 Democracy Blvd., Room 632Telephone: 301-451-5096Fax: 301-480-8322E-mail: [email protected]