DNA Replication Model Nick Constant
NickConstantDNAReplication
Jun 27, 2015
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DNA Replication Model
Nick Constant
This is a DNA molecule. On each side in this example, there are 9 nucleotides. A nucleotide is made up of a phosphate, a sugar, and a base. The four examples of bases are adenine, thymine, cytosine and guanine. Adenine and thymine are always paired and cytosine and guanine are paired. To replicate, the hydrogen bond between the bases much be split for each pair. DNA replication occurs during the S stage of mitosis in the nucleus.
Key:
- Adenine - Guanine
- Thymine - Phosphate
- Cytosine - Sugar - DNA Helicase
5’
5’
3’
3’
To replicate, the helicase unwinds of DNA and the hydrogen bonds between the bases are broken.
Key:
- Adenine - Guanine
- Thymine - Phosphate
- Cytosine - Sugar - DNA Helicase
To replicate, the helicase unwinds of DNA and the hydrogen bonds between the bases are broken.
Key:
- Adenine - Guanine
- Thymine - Phosphate
- Cytosine - Sugar - DNA Helicase
To replicate, the helicase unwinds of DNA and the hydrogen bonds between the bases are broken.
Key:
- Adenine - Guanine
- Thymine - Phosphate
- Cytosine - Sugar - DNA Helicase
To replicate, the helicase unwinds of DNA and the hydrogen bonds between the bases are broken.
Key:
- Adenine - Guanine
- Thymine - Phosphate
- Cytosine - Sugar - DNA Helicase
To replicate, the helicase unwinds of DNA and the hydrogen bonds between the bases are broken.
Key:
- Adenine - Guanine
- Thymine - Phosphate
- Cytosine - Sugar - DNA Helicase
To replicate, the helicase unwinds of DNA and the hydrogen bonds between the bases are broken.
Key:
- Adenine - Guanine
- Thymine - Phosphate
- Cytosine - Sugar - DNA Helicase
To replicate, the helicase unwinds of DNA and the hydrogen bonds between the bases are broken.
Key:
- Adenine - Guanine
- Thymine - Phosphate
- Cytosine - Sugar - DNA Helicase
To replicate, the helicase unwinds of DNA and the hydrogen bonds between the bases are broken.
Key:
- Adenine - Guanine
- Thymine - Phosphate
- Cytosine - Sugar - DNA Helicase
To replicate, the helicase unwinds of DNA and the hydrogen bonds between the bases are broken.
Key:
- Adenine - Guanine
- Thymine - Phosphate
- Cytosine - Sugar - DNA Helicase
To replicate, the helicase unwinds of DNA and the hydrogen bonds between the bases are broken.
Key:
- Adenine - Guanine
- Thymine - Phosphate
- Cytosine - Sugar - DNA Helicase
To replicate, the helicase unwinds of DNA and the hydrogen bonds between the bases are broken.
Key:
- Adenine - Guanine
- Thymine - Phosphate
- Cytosine - Sugar - DNA Helicase
Leading Strand
Lagging Strand
To replicate, the helicase unwinds of DNA and the hydrogen bonds between the bases are broken.
Key:
- Adenine - Guanine
- Thymine - Phosphate
- Cytosine - Sugar - DNA Helicase
To replicate, the helicase unwinds of DNA and the hydrogen bonds between the bases are broken.
Key:
- Adenine - Guanine
- Thymine - Phosphate
- Cytosine - Sugar - DNA Helicase
To replicate, the helicase unwinds of DNA and the hydrogen bonds between the bases are broken.
Key:
- Adenine - Guanine
- Thymine - Phosphate
- Cytosine - Sugar - DNA Helicase
To replicate, the helicase unwinds of DNA and the hydrogen bonds between the bases are broken.
Key:
- Adenine - Guanine
- Thymine - Phosphate
- Cytosine - Sugar - DNA Helicase
To replicate, the helicase unwinds of DNA and the hydrogen bonds between the bases are broken.
Key:
- Adenine - Guanine
- Thymine - Phosphate
- Cytosine - Sugar - DNA Helicase
To replicate, the helicase unwinds of DNA and the hydrogen bonds between the bases are broken.
Key:
- Adenine - Guanine
- Thymine - Phosphate
- Cytosine - Sugar - DNA Helicase
To replicate, the helicase unwinds of DNA and the hydrogen bonds between the bases are broken.
Key:
- Adenine - Guanine
- Thymine - Phosphate
- Cytosine - Sugar - DNA Helicase
To replicate, the helicase unwinds of DNA and the hydrogen bonds between the bases are broken.
Key:
- Adenine - Guanine
- Thymine - Phosphate
- Cytosine - Sugar - DNA Helicase
To replicate, the helicase unwinds of DNA and the hydrogen bonds between the bases are broken.
Key:
- Adenine - Guanine
- Thymine - Phosphate
- Cytosine - Sugar - DNA Helicase
First, on the leading strand, DNA polymerase III adds the five phosphate end of a free floating nucleotide to the exposed 3’ OH end on the single stranded DNA continuously. This elongates toward the replication fork. On the lagging strand, DNA polymerase III forms Okazaki fragments discontinuously with the help of other fragments. This elongates away from the replication fork.
Key:
- Adenine - Guanine
- Thymine - Phosphate
- Cytosine - Sugar - DNA Helicase
First, on the leading strand, DNA polymerase III adds the five phosphate end of a free floating nucleotide to the exposed 3’ OH end on the single stranded DNA continuously. This elongates toward the replication fork. On the lagging strand, DNA polymerase III forms Okazaki fragments discontinuously with the help of other fragments. This elongates away from the replication fork.
Key:
- Adenine - Guanine
- Thymine - Phosphate
- Cytosine - Sugar - DNA Helicase
First, on the leading strand, DNA polymerase III adds the five phosphate end of a free floating nucleotide to the exposed 3’ OH end on the single stranded DNA continuously. This elongates toward the replication fork. On the lagging strand, DNA polymerase III forms Okazaki fragments discontinuously with the help of other fragments. This elongates away from the replication fork.
Key:
- Adenine - Guanine
- Thymine - Phosphate
- Cytosine - Sugar - DNA Helicase
First, on the leading strand, DNA polymerase III adds the five phosphate end of a free floating nucleotide to the exposed 3’ OH end on the single stranded DNA continuously. This elongates toward the replication fork. On the lagging strand, DNA polymerase III forms Okazaki fragments discontinuously with the help of other fragments. This elongates away from the replication fork.
Key:
- Adenine - Guanine
- Thymine - Phosphate
- Cytosine - Sugar - DNA Helicase
First, on the leading strand, DNA polymerase III adds the five phosphate end of a free floating nucleotide to the exposed 3’ OH end on the single stranded DNA continuously. This elongates toward the replication fork. On the lagging strand, DNA polymerase III forms Okazaki fragments discontinuously with the help of other fragments. This elongates away from the replication fork.
Key:
- Adenine - Guanine
- Thymine - Phosphate
- Cytosine - Sugar - DNA Helicase
First, on the leading strand, DNA polymerase III adds the five phosphate end of a free floating nucleotide to the exposed 3’ OH end on the single stranded DNA continuously. This elongates toward the replication fork. On the lagging strand, DNA polymerase III forms Okazaki fragments discontinuously with the help of other fragments. This elongates away from the replication fork.
Key:
- Adenine - Guanine
- Thymine - Phosphate
- Cytosine - Sugar - DNA Helicase
First, on the leading strand, DNA polymerase III adds the five phosphate end of a free floating nucleotide to the exposed 3’ OH end on the single stranded DNA continuously. This elongates toward the replication fork. On the lagging strand, DNA polymerase III forms Okazaki fragments discontinuously with the help of other fragments. This elongates away from the replication fork.
Key:
- Adenine - Guanine
- Thymine - Phosphate
- Cytosine - Sugar - DNA Helicase
First, on the leading strand, DNA polymerase III adds the five phosphate end of a free floating nucleotide to the exposed 3’ OH end on the single stranded DNA continuously. This elongates toward the replication fork. On the lagging strand, DNA polymerase III forms Okazaki fragments discontinuously with the help of other fragments. This elongates away from the replication fork.
Key:
- Adenine - Guanine
- Thymine - Phosphate
- Cytosine - Sugar - DNA Helicase
First, on the leading strand, DNA polymerase III adds the five phosphate end of a free floating nucleotide to the exposed 3’ OH end on the single stranded DNA continuously. This elongates toward the replication fork. On the lagging strand, DNA polymerase III forms Okazaki fragments discontinuously with the help of other fragments. This elongates away from the replication fork.
Key:
- Adenine - Guanine
- Thymine - Phosphate
- Cytosine - Sugar - DNA Helicase
First, on the leading strand, DNA polymerase III adds the five phosphate end of a free floating nucleotide to the exposed 3’ OH end on the single stranded DNA continuously. This elongates toward the replication fork. On the lagging strand, DNA polymerase III forms Okazaki fragments discontinuously with the help of other fragments. This elongates away from the replication fork.
Key:
- Adenine - Guanine
- Thymine - Phosphate
- Cytosine - Sugar - DNA Helicase
Okazaki Fragments
First, on the leading strand, DNA polymerase III adds the five phosphate end of a free floating nucleotide to the exposed 3’ OH end on the single stranded DNA continuously. This elongates toward the replication fork. On the lagging strand, DNA polymerase III forms Okazaki fragments discontinuously with the help of other fragments. This elongates away from the replication fork.
Key:
- Adenine - Guanine
- Thymine - Phosphate
- Cytosine - Sugar - DNA Helicase
5’
5’5’
5’
3’
3’
3’
3’
DNA Primase creates an RNA primer, which is then uses to replicate DNA. DNA ligase “stitches together” pieces of DNA to form a longer strand.
Key:
- Adenine - Guanine
- Thymine - Phosphate
- Cytosine - Sugar - DNA Helicase
5’
5’5’
5’
3’
3’
3’
3’