NextPharma Technologies Experts in the production of Pellets

© NextPharma Technologies 2006

NextPharma Technologies

Experts in the productionof Pellets


What We Can Do For You

Formulation and Development of new products:Our Development Department is specialized in the development and formulation of new pellets and granule products. Its laboratory is specially equipped with the necessary technologies for this task.

Production:The production of aqueous and organic granules, extrudates and pellets, coating, tabletting and capsule filling of granules and pellets.


What We Can Do For You

Quality Control and Contract AnalysisModern and highly qualified laboratory for the analysis of all types of products (our specialist for the analysis of pellets), stability testing and development of analytical method.


Technologies

Granulation:Aqueous and organic granulation (high shear mixer and fluid bed granulation)

Extrusion / Spheronisation:For the production of homogeneous and organic extrudates and pellets

Coating:Aqueous or organic coating of granules and pellets

LayeringProduction of heterogeneous pellets using suspension-layering


Options for characteristics of produced pellets

Controlled ReleaseCan be achieved through:-Coating with special films (gastro resistant or pH independent diffusion film)-Difussion from Matrix-pellets

Odour or Taste MaskingBy coating the pellets with specific films in order to mask the unsuitable odour or taste

Colouring / FlavouringTo enhance the patient compliance / acceptance by coating the pellets with accordingly special layers


Production of pellets with extrusion / spheronisation

Blending & moisteningHigh shear mixer:Ring die press (extruder):

Extrusion

extrudate

SpheronisationSpheroniser:

moist pellets

CoatingKugelcoater:Fluid bed

dryer:Drying


Extrusion / Spheronisation Equipment

Blending & Moisting: Diosna P 400



Extrusion: Schlüter PP-127



Spheronisation: Schlüter RM-700



Fluid Bed Drying: Hüttlin HD 400


Production of pellets with suspension layering

Non-pareil

Layers with active substance

Spraying nozzle

Layers containing the active are sprayed onto non-pareils in a Kugelcoater (Bowl-coater)


Coating and Layering Equipment

Fluid Bed Coater and Granulator: Hüttlin HKC 300-TJ


NextPharma Technologies

NextPharma Technologies Experts in the production of Pellets

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