Neuropathic Pain Etiology and Treatment
Neuropathic PainEtiology and Treatment
Pain ConceptsCharacteristic Acute Pain Chronic Pain
Cause Generally known
Often unknown
Duration of Pain
Short, well- characterized
Persists after healing, ≥3 months
Treatment approach
Underlying disease
Underlying disease and pain disorder
Pain Concepts• Types of Neuropathies
– Focal• Mononeuritis• Entrapment
– Diffuse• Proximal• Distal
– Large fiber– Small fiber
Pain Concepts
• Problems in Neuropathic Pain– Many patient with neuropathic pain
continue to suffer, despite optimal therapy– Development of rationally based, novel
treatments has been slow– Neural mechanism for ‘pain’ is unproven
for the common syndromes (DM Peripheral neuropathy/Postherpetic neuralgia)
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