Natural selection is a major mechanism of evolution (1.A.1) Big Idea …edhsgreensea.net/APBiology/Unit_Review_PPT/APBio1A1.pdf · 2012-08-30 · AP Biology Curriculum 2012-2013 Big
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• Individuals with more favorable phenotypes are more likely to survive and produce more offspring, thus passing traits to subsequent generations (Descent With Modification).
“I think” Darwin’s 1837 sketch
b. Evolutionary fitness is measured by reproductive success (aka: Darwinian Fitness).
Natural selection is a major mechanism of evolution (1.A.1)
d. Environments can be more or less stable or fluctuating,– and this affects evolutionary rate and direction; – different genetic variations can be selected in each
Natural selection is a major mechanism of evolution (1.A.1)
PBS Evolving Ideas - video 4 How Do We Know Evolution Happens? (7:00 mins)http://www.pbs.org/wgbh/evolution/educators/teachstuds/svideos.htmlhttp://www.youtube.com/watch?v=xkwRTIKXaxg
g. Conditions for a population or an allele to be in Hardy-Weinberg equilibrium are:
- 1. a large population size,
- 2. absence of migration,
- 3. no net mutations,
- 4. random mating and
- 5. absence of selection.
• These conditions are seldom met in real populations.
• By convention, if there are 2 alleles at a locus, p and q are used to represent their frequencies
• The frequency of all alleles in a population will add up to 1
– For example, p + q = 1
• If p and q represent the relative frequencies of the only two possible alleles in a population at a particular locus, then– p2 + 2pq + q2 = 1– where p2 and q2 represent the frequencies of the
homozygous genotypes and 2pq represents the frequency of the heterozygous genotype
The Hardy-Weinberg Principle
Fig. 23-6
Selecting alleles at random from a gene pool
Frequencies of allelesAlleles in the population
Gametes produced
Each egg: Each sperm:
80%chance
80%chance
20%chance
20%chance
q = frequency of
p = frequency ofCR allele = 0.8
CW allele = 0.2
1) The allele frequencies of the population are 0.8 (80%) and 0.2 (20%).
2) If all of these alleles could be placed in a large bin, 80% would be CR and 20% would be CW.
3) Assuming mating is random, each time two gametes come together, there is an 80% chance the egg carries a CR allele and a 20% chance it carries a CW allele.
The Hardy-Weinberg principle
Fig. 23-7-4
Gametes of this generation:
64% CR CR, 32% CR CW, and 4% CW CW
64% CR + 16% CR = 80% CR = 0.8 = p
4% CW + 16% CW = 20% CW = 0.2 = q
64% CR CR, 32% CR CW, and 4% CW CW plants
Genotypes in the next generation:
SpermCR
(80%)
CW
(20%
)
80% CR ( p = 0.8)
CW (20%)
20% CW (q = 0.2)
16% ( pq) CR CW
4% (q2) CW CW
CR
(80%
)
64% ( p2) CR CR
16% (qp) CR CW
Eggs
If the gametes come together at random, the genotype frequencies of this generation are in Hardy-Weinberg equilibrium:
Gametes for each generation are drawn at random from the gene pool of the previous generation.
With random mating, these gametes will result in the same mix of genotypes in the next generation
• We can assume the locus that causes phenylketonuria (PKU) is in Hardy-Weinberg equilibrium given that:– The PKU gene mutation rate is low– Mate selection is random with respect to whether or not an
individual is a carrier for the PKU allele
• PKU metabolic disorder resulting from homozygosity for a recessive allele:– left untreated leads to mental retardation– newborns are tested for PKU at birth– symptoms can be lessened with a phenylalanine-free diet
Applying the Hardy-Weinberg Principle (p. 474-475)