NanoTera_hdm

8/2/2019 NanoTera_hdm

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Science and Technology in a World of

Change: a New Renaissance?

Hugo De Man

Em. Prof. K.U.Leuven

Em. Senior Fellow IMEC

[email protected]


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Outline

The changing world and its challenges

Technologies for the 21st century

Towards a new renaissance?

Hugo De Man2


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Hugo De Man3

Changing World of Science and Technology

1800 1900 2000

Phys.Sc.

Th

At

QuLife

Sciences

Scale Macro Micro

Technology

Energy Mfg. Goods Information

Era Science

MEl

NeuroScience

Intelligent

systems?

+Bio+Nano+Energy

Convergence

IntelligenceComplexity

Techno-Science

Nano


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Hugo De Man4

21 Information &Communication(ICT)

IV

Brain LaborKnowledge

Smart Systems

PersonalisationSocial NetworkingNanomedicine

Chip - DNA all @ Nano-scale

Nano- Bio andNeurotech.

III

+

Changing Industrial World of the 21st Century

Man. LaborCapital

Fossil Fuel

Electricity

Mat. GoodsMech. Mobility

20Century Technology Production factor Product

I

II

Sustainability


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Hugo De Man5

Societal Challenges of the 21st Century

- Energy, water, food for 9 Billion people by 2050

- Soaring cost of ageing and healthcare

- Keeping mobility safe and sustainable

- Managing complexity of globalized world

- Maintaining prosperity in a flattening* worldIn a world of shared technology social innovation must make the difference

*T.L. Friedman: The World is Flat ISBN: 0374292884


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Hugo De Man6

Energy, Climate Change and Fossil Fuel Depletion

Fossil Fuels

Nucl. HydroGeo

Sun

Wind

Biomass

CO2neutraltech

CleanCoal

A huge challenge!1GW carbon-neutral /day for 50y!Feasible? In 2010 only 25% done!

US DOE

DT(2100) < 2oC

Source: IPCC

TransportBuild.

Ind.


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Hugo De Man7

Converging Nanotech for Future Energy

Solar power systems (new silicon-nano-tech boom industry >1/2silicon consumption) but renewable energy sources requires:

Smart Grid = distributed electricity production&consumptioncontrolled by the internet (largest manmade smart systemever?)

Intelligent ICT systems = smart metering and sensor networks(can save 30% power in buildings and mfg. systems)

Smart LED, OLED lighting can save up to 240 Gwatt of power by2030

Hybrid and Plug-in E-cars can save 30% fossil fuels by 2030.(Nano tech for power electronics, supermagnets, batteries, fuelcells, smart cars & traffic control)

Non-food biofuels by synthetic biology (engineering life)


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Hugo De Man8

Converging Nanotech for Future Energy

Solar power systems (new silicon-nano-tech boom industry >1/2silicon consumption) but renewable energy sources requires:

Smart Grid = distributed electricity production&consumptioncontrolled by the internet (largest manmade smart systemever?)

Intelligent ICT systems = smart metering and sensor networks(can save 30% power in buildings and mfg. systems)

Smart LED, OLED lighting can save up to 240 Gwatt of power by2030

Hybrid and Plug-in E-cars can save 30% fossil fuels by 2030.(Nano tech for power electronics, supermagnets, batteries, fuelcells, smart cars & traffic control)

Non-food biofuels by synthetic biology (engineering life)


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Hugo De Man9

Ageing and Healthcare

In 2025

The young will be in Africa and India In the OECD countries >30% will be over 60

Doubling of lifestile related chronic diseases next 25y

Age

H

C

cost/person

y()


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Hugo De Man10

Impact

Health & Care cost soaring Europe: 10% GDP, *2/20 year (BAU) Drying pharma pipelines Development cost of new drug 7B

A challenge for techno-science Convergence of Bio-Nano-ICT-Neuro tech will lead to:

Affordable predictive, preventive and personalized medicine

Cheaper or for the happy few? Challenge 1: low cost systems vs. reliability, complexity, privacy Challenge 2: paradigm shift in pharma and healthcare business


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Hugo De Man11

Outline

The changing world and its challenges

Technologies for the 21st century

Towards a new renaissance?


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Hugo De Man12

Technologies for 21st Century

Towards intelligent ICT systems

Convergence with Nano-Bio-Neuro


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Hugo De Man

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The Changing World of ICT

XX Century

Locality bound PC

Wired (preprogrammed)

Local Storage

Internet of Data

Info CONSUMER

Hard- Software

XXI Century

Mobile PDA (a4)

Wireless (context sensitive)

Cloud Computing

Internet of Smart Things

Info PROSUMER

Hard- Soft- AND Wetware

a4 : anyplace-anytime-to-anybody-anything


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Hugo De Man14

ICT Technology Drivers

Personal MobileGateway to a4

Polymer & FlexibleElectronics

3-D IntegrationInvisible ICTSmart Dust

+10 years of More Mooreto sub 10nm size+ emerging More than Mooretech

Smart Sensorsand Actuators

More Moore More Than Moore

WWW


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Hugo De Man imec restricted 2008 15

Internet of Data Internet of Things

From Consumer to Prosumer


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Hugo De Man16

Secure, reliable computing en communicationinvisiblyembeddedin every-thing and every-one

A pervasive,context awareelectronics ambient, sensitiveand responsive to the presence of people

Towards Ambient Intelligence


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Hugo De Man17

AmI is changing the way peopleexperience their physicalenvironment

Requires a holistic design approachfrom society needs to technology

Need for renaissance engineersAnd renaissancehumanists

Able to translate complexity intoSense and Simplicity

Source: E. Aarts, Philips

Living Labs!


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Living Labs: User Driven Open Innovation


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Hugo De Man19

AmI for Ageing Care

Source: IntelAgeing In Place

EU Ambient Assisted LivingTelemedicine and TelecareSocial Contact InterfacesRemote drug prescriptionHome Robotics


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AmI Telemedicine-Telecare

Hugo De Man20

H DE man cmbf-2011 20

SmartWirelessSensors

BAN

SmartPhoneInternet

4G

3G


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Growth of Body Area Sensor Markets


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Hugo De Man22

AmI for Energy Efficient Cars and Safe Traffic

Smart SensorsActive Safety

Drive by wire Hybrid-EV

NetworkedCars-Traffic Control

ITS

Car cocoon / Autonomous Driving

Source: MEDEA+


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Hugo De Man23

J.Rabaey ASPDAC 08

$$$$

$$


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Hugo De Man24

Three Widely Different Metrics

Core Infrastructure: supercomputer/chip > 10Tops, < 100Watt, < 100 , Tbit , GP programmability

More Moore Driver

Personal Mobile Gateway 200 Gops , < 2Watt, < 10 , 100GB SSD

Cognitive Radio, Smart senses, Multimedia Services

Intelligence, Flexibility by embedded software

More Moore + More than Moore (3D)

Sensory Swarm Wireless interface to non-living and living things

Heterogeneous technologies and architectures

< 100 mW,


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Hugo De Man25

The CMOS Supercomputer Chip in 2020 ?

IF WE SUCCEED* THEN:

1 cm2 chip in 10nm technology @ 100 fold improvement)

* In 8 years:

Si-Ge Tunnelfets, Memristor crosspoint SRAM, EUVlitho, fault-tolerant architectures, variability resilientdesign, // programming issue solved...


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Hugo De Man26

Hw/Sw Design Cost : Moores Antilaw?

Will software limit More Moore for computation?

0.1

1

10

100

1000

104

1995 2000 2005 2010 2015

Year

After: Renesas and TSMC

90nm

130

180

250

80Mtr

20

40

5

TSMC

Renesas

1 B$


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Hugo De Man27

What will further scaling be good for?

A few supercomputer Teraop platforms

Solid State Disks (Flash), FPGAs

A myriad possibilities for smart mobile systemsand smart sensors if design compilers availablefor: 1 mm2 250 Gops @ 50 mW for mobile access chips

< 1 mm2 250 Mops @ 50 mW for sensory swarm motes

Can live with Ion < 0.2 mA/mm but Ioff< 30pA/mm


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Hugo De Man28

A Rapidly Changing Semi Industry Ecosystem

Scaling CMOS=more compute power and bandwidth Design & Development costs rise exponentially

Sharing development cost in a few R&D consortia

Limited numberof Hyperscaling companies

2..3 main providers supercomputer core infrastructure chips Memory commodity chips Advanced foundries in the east serving:

EU

- Majorityof consumer oriented semiconductor companies:

Becoming fablite, fabless system chip providers Serving service and ambient intelligent system companies

- More than Moore interfacing component essential part of it CMOS + MEMS, Power, 3D, bio- nano interfacing


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Hugo De Man29

More Than Moore: a Different Game

Get to the ultimate limits of electronics Miniaturization (


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Convergence of UCMOS with Non-E World

NanoFluidics

IntelligenceRadio

100mWMemory

Processor

RF Chip

DNA Chip

MEMS

Battery

ImageSensor

MemoryMemory

ProcessorProcessor

RF ChipRF Chip

DNA Chip

MEMSMEMS

BatteryBattery

ImageSensor

Source SAMSUNG


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Hugo De Man31

Heterogeneous System Engineering

Ad Hoc Transducer network protocol ULP, ULV sensor + signal conditioning + A/D

MicroWatt level computing

UWB communication and location awareness

Power Management

Energy Scavenging

Packaging

Multidisciplinarity in a few mm3


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TransportationAutomotiveAvionics

Healthcare

Gaming/Personal Devices

Instrumentation

Communication

2009 IMEC

MicroMirrors Gyro VibrationalPower

Neuro probes ThermalPower

Molecularsensor

Actuator Fluidics

DrugDelivery

Cell Sensor

MicroMirrors

Gas Sensor ECG/EEG

Probe Memory RF switch Timing Device

Cooling

PressureSensor

Hyperspectral mCam

Gyro

MTM Technologies for Tomorrows Products


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Hugo De Man33

Technologies for 21st Century

Towards intelligent ICT systems

Convergence with Nano-Bio-Neuro


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Convergence at the Nano-Scale

cmmnm

BIOTECH

devices

x109

NANOELECTRONICS

31nm31nm


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Chi

Electronics meets Bio at Nano-Scale

electrical

action potential

chemical

neurotransmitter

Interpretation-control-transmission

K.U.LeuvenIMEC-VIB

NERFproject

Transducers

Computing

Communication

Neurons

1) In VitroBrain Research

Drug testing

l l


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Chi

Electronics meets Bio at Nano-Scale

electrical

action potential

chemical

neurotransmitter

ICT Interpretation-control-transmission

Probes

Neurons

K.U.LeuvenIMEC-VIB

NERFproject

2) In vivo

NeuroprobesAlzheimerParkinsonEpilepsyBrainprosthesis


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Smart Parkinson Electrodes


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Convergence at the Nano-Scale

cmmnm

BIOTECH

Nano ParticlesNANOTECH

transistor

x1012

NANOELECTRONICS

31nm31nm

Targeted Drug

Delivery

Biosensors

k l f h l


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Market evolution of NanoTech Drug Delivery

Hugo De Man39

http://www.cientifica.com/

2021136B$

di i d C


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Nano-Medicine and Cancer Treatment

Hugo De Man40

http://en.wikipedia.org/wiki/Nanomedicine

M l l Di i P i f C


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Molecular Diagnostics at Point of Care


Source: R.Pauwels Biocartis

M L f Bi t h th 100$ G


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Moores Law of Biotech...the 100$ Genome

2011 2012 2013 2014 2015

$1.0

$10.0

$100.0

$1000.0

$10000.0

$100000.0

$1000000.0

$10000000.0

$100000000.0

2001

2003

2004

2005

2007

2008

2010

2011

2013

Cost per Genome

http://www.genome.gov/27541954

Ultradeepsequencer

(>10Gbp/run,


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Hugo De Man imec restricted 2008 43Bio-Nano-ICT convergence at all stages!

Genome Chip

Molecular Diagnostics

BioSensorsTelemed.

Targeted Drug Delivery

Bio-informatics

BioSensorsTelemed.

T d N R i ?


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Hugo De Man44

Towards a New Renaissance?

Progress is in the merger of

previously unconnected techno-culturesdriven by societal needs

SocietalChallenges

AmbientIntelligentSystems

More

Moore

More Than

Moore

ComputerScience

LifeSciencesNano

Technology

Neuro-Science

IntelligenceSmart sensing &

actuating

N d d R i E i S i ti t


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Needed: Renaissance Engineers, Scientists

M/W ready for social innovation:

Team player skills

tech nerds With cross-disciplinary communicationskills

Trained in creative thinking at system level

Lifelong in(ter)dependent learning skills

Able to cope with diversity and change

Co-architect of society Putting a societal vision into a solution

With economic value:entrepreneurial spirit

Prepared to take part in public debate

Hence need for:Sociology for Future Engineers

B t h d id h ?


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Hugo De Man46

Prevail* Desirable Societal GoalsEco-Economical Win-Win

Long Term GlocalPolitics & Economy

Media Education

SOCIAL SCIENCES

Objectives

RegulationsLegal Stability

But who decides where we go?

Heaven(Transhumanists) : Enhanced superhumans

Hell ( Luddites) Brave New World, Self-destruction*Joel Garreau: Radical Evolution

TECHNO-SCIENCE

ICTNanoBio

EnergyMedicine

Neuro

TECHNO-LITERACYPublic Outreach

The efo e


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Hugo De Man47

Therefore

More than the engineers business!

Techno-scientific literacy a must for everybody!

Politics, Media, Citizens,Education

- Universities :social sciences, arts and humanities?

Hence besides Sociology for Future Engineers

Future prosperity is strongly linked to correcttechnological answers to the grand challenges of the

21st century.

Techno Science for Future Philosophers


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Hugo De Man48

Techno-Science for Future Philosophers

Im assuming that everyone in this class isgoing to be a leader some day, My goal is that they can lookbeyond the newspapers andunderstand things in order to make wise

decisions Understanding technology is evenmore urgentfor the politician, who has to make rapiddecisions that may have enormousconsequences

Physics for Future Presidents

Prof. Muller U.C. Berkeley

http://muller.lbl.gov/teaching/Physics10/PffP.html

Why not at ouruniversities?

Techno Literacy Starting Early: RVO Society


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Techno-Literacy Starting Early: RVO Society

Promote creative and societal aspects of techno-sciencein primary and secondary schools by doing.

Train the trainersCERA-RVO Society: engineering thesis in social-profit sector

Chip-Chip Hurray! IR 13

Are our universities ready for that?


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Hugo De Man50

Are our universities ready for that?

Today Tomorrow

Sciences Engineering SocialSciences

Hyperspecialized publicationfever

Mono-disciplinary researchfunding

Publication oriented Eng. Ph.D.

Academic career

Techno-science for SocialInnovation

Cross-disciplinary research andeducation

Cross-disciplinary funding

Innovation oriented Eng. Ph.D.

Technical leadership

Entrepreneurial thinking

K U Leuven Syn Bio Team designs Dr Coli


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Hugo De Man51

K.U.Leuven Syn Bio Team designs Dr-Coli

4 EE engineers, 4 bioengineers, 4 biochemists

Synthesis of smart drug delivering bacterium

Gold medal at i_GEM contest MIT 2008

Organizing Techno Science Research
http://2008.igem.org/Team:KULeuven/Project/Inputhttp://2008.igem.org/Team:KULeuven/Project/Memoryhttp://2008.igem.org/Team:KULeuven/Project/CellDeathhttp://2008.igem.org/Team:KULeuven/Project/Resethttp://2008.igem.org/Team:KULeuven/Project/Inverterhttp://2008.igem.org/href=http://2008.igem.org/Team:KULeuven/Project/Outputhttp://2008.igem.org/wiki/images/d/da/Students.JPG


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Hugo De Man52

Organizing Techno-Science Research

Theme driven

Crossdisciplinary CoE

DemonstratorsInnovators

IP, Methods, Tools

Spin-offs

Socio-ecoChallenges

SystemIndustry

AcademiaIndustry

cc1

cc2

ccn

Competence

Centers

S

Y

S

TE

C

H

R D

Innovation

Policy making

Examples : Nano Tera IMEC CITRIS


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Hugo De Man53

Examples : Nano-Tera, IMEC, CITRIS,

Themes drive by Societal Challenges

Tackled by cross-disciplinary teams

In economical win-win mode with industry

Conclusions


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Hugo De Man54

Conclusions

21

st

century: mankinds largest challenges ever Converging technologies can lead to solutionsiff driven by political

leadership on glocal scale

Urgent need on long term thinking and action shareholder next

quarter / next election mentality

Can lead to huge econ-ecolwin-win opportunities

Needed: renaissance engineers, scientists, humanists

Trained in thematic cross-disciplinary research organizations forsocial innovation

Techno-scientific literacy needed at all levels of education


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