4/6/19 1 None Look at myopia in a different light Understand different treatments options There is no “safe” level of myopia Why we need to treat Assess risk factors Types of Treatment › Do nothing… › Glasses › Atropine › Soft Multifocal, Soft Ortho-k › Ortho-k 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100% 1900 1975 2000 2025 2050 Incidence of Myopia in US 10% 22% 2000 2% 2050 In 2016 the WHO and the Brien Holden Vision Institute recognized myopia as a public health issue. 3 1
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Myopia Control & Management Handout 04-28-2019...4/6/19 1 None Look at myopia in a different light Understand different treatments options There is no “safe” level of myopia Why
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� None
� Look at myopia in a different light � Understand different treatments options � There is no “safe” level of myopia
� Why we need to treat � Assess risk factors � Types of Treatment › Do nothing… › Glasses › Atropine › Soft Multifocal, Soft Ortho-k › Ortho-k
0%
10%
20%
30%
40%
50%
60%
70%
80%
90%
100%
1900 1975 2000 2025 2050
Incidence of Myopia in US
10% 22%
2000
2%
2050
In 2016 the WHO and the Brien Holden Vision Institute recognized myopia as a public health issue.3
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USA 42%
Chile 20%
Africa 10%
Europe 20-30%
China 80-90%
India 19%
Taiwan 83%
Aus 20-30%
Rob Gerowitz, OD, FOAA
� Low myopia < -3.00 � Moderate myopia -3.00 and -6.00 � High myopia > -6.00
� 9 yo Asian Male � -2.50 OU � > 3 hours @ near � <1 hour outdoors � Mom: -2.00 � Dad: -4.00 � 1st Rx: 7 Yo
� 6 yo Asian Male � Current Rx: pl OU � Cyclo Rx: +0.75 OU � Ortho @ D, 3 Exo @ N � MEM: +1.25 (Lag) � > 2 hours @ near � <1 hour outdoors � Mom: -2.00 � Dad: -4.00 � Brother: -2.50
� Genetics � Near Work � Outdoor time � Education � Ethnicity � Age of Onset › Current prescription
� Other (prematurity, diet, light exposure)
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2x risk 5-6x risk
< 1.5 hours > 3 hours
2.6x risk
� Children most at risk= � Children with
emmetropia spend 3.7 hours per week more outdoors than those with myopia 6
Outdoor time Nearwork
40- 80 minutes ↓23% to 50%
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� Light level › Light towards the UV
end of the spectrum slows eye growth and myopia
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� Dioptric field of view › Differences in defocus across
viewing distances in indoor vs outdoor environments.14
� Outside = Dioptric value of 0
� Light- Dopamine Theory14
� Winter Months › Progress 3-4x Faster
Risk Factors for Developing Myopia
Risk factors for fast progression of Myopia
Age ≤9 years old ≤9 years old
Refractive error Less plus in refraction NA
Current Progression NA > -1.00 D per year
Parental Myopia At least one myopic parent
At least one myopic parent
Ethnicity East Asian East Asian
Time Spent Outdoors < 1.5 hours per day NA
Time Spent on Near work > 2.5 hours per day NA
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� The earlier the onset the higher chance for high myopia
� Risk of Glaucoma 67% � Risk of PSC Cataract 74% � Risk of Retinal Detachment 98% � Risk of Myopic Maculopthy 99%
� Emmetropia ~ 23-24mm
� 0.1mm= 0.25 diopters � 1.0mm= 2.75 diopters
16.8 mm 23.6 mm Axial Length Visual Impairment by
age 60 (odds ratio) Prevalence of Visual
Impairment by age 75
24-26mm 1 (reference) 4%
26-28mm 2x 25%
28-30mm 11x 27%
30mm+ 25x 90%
5
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� Up to age 12 ~ 0.1mm per year � < 12 more than 0.1 is okay (grow faster) � >12 a little less than 0.1(grow slower) � >0.2mm monitor closely, may modify tx
*Diopters are easy to measure, but myopia control is about axial length control
keep myopia below -3.00 and
axial length below 26mm
� History (Family history, near work, outdoor time)
� Age of onset, progression (if myopic) � Visual acuity (uncorrected, best
corrected) � Corneal topography � Binocular vision (lag, eso/exophoria) � Axial Length (average of at least 5
� 0.05% atropine was most effective in controlling SE progression and AL elongation over a 1 year period
� Level 1 evidence supports use of atropine to prevent myopia progression
� Rebound is minimized by using low dose atropine, especially 0.01%
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� 1 drop 0.01% (QHS) daily � Start in kids 4 to 12 years of
age who are at least –0.50 D myopic with: › History of at least 0.5 D
progression over last 6 months › Family history › Near work/outdoor time
� Treat for at least 2 years or to 15 years of age
� In the first 6 months, may still see prog-ression
� After 6 months, progression should slow to –0.50 D change, or less/year
� Slows rate of progression by 30% - 50%
� If still progressing >-0.50D increase to 0.02%
� 6 week follow up (make sure they got their drops and are using them)
� 3 month after starting to ensure no side effects/compliance
� Start assessing treatment efficacy at 6 months � Assess for progression every 6 months › VA › Binocular vision › A-scan › Refraction/Topography › If >0.50 D of change at 1year consider changing
dosage
� Biofinity D Lens, Proclear D Lens � +4.00 to -12.25 (-0.25) � One add up to +3.00
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� 7 years or older � Progression >0.50 diopters per year � Family history � Near work vs outdoor time
� Assess treatment every 3-6 months › VA’s › Ret (cyclo once yearly) › A-scan
� Re-educate on hygiene/care
� Extended depth of focus � Center distance
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� NaFL not visible if tear lens is <20 microns
� ~7 or older � -1.00 to -4.00 (FDA Approved up to -6.00) � Myopia > Astigmatism � Cyl < -0.75 WTR central � K’s between 41-45
� Central bearing � Tear Reservoir � Mid Peripheral bearing � Edge lift � Good centration
� Refraction � HVID � K’s � Topography
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� Multi-site study across USA 267 patients followed for 3 years
� Children aged 7-14 � Emerald lens design vs PureVision � Empirical fitting of Emerald successful in 80%
improving to 95% with one lens change › 32% drop out of OK = discomfort › 34% drop out of soft lens control = loss of interest
� OK group progressed by -0.13D over 3 years, and soft lens wearers by -1.03D
� Daily disposable: › 2 per 10,000 wearers per year
� Silicon hydrogel › 12 per 10,000 wearers per year
� Ortho-k (pediatrics) › 13 per 10,000 wearers per year
� Extended wear › 52 per 10,000 wearers per year
� Risk for all contact lens modalities › 1 per 10,000 wearers per year
� 9 yo Asian Male � -2.50 OU � > 3 hours @ near � <1 hour outdoors � Mom: -2.00 � Dad: -4.00 � 1st Rx: 7 Yo
� Patient in Ortho-k ~6 months
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� 6 yo Asian Male � Current Rx: pl OU � Cyclo Rx: +0.75 OU � Ortho @ D, 3 Exo @ N � MEM: +1.25 (Lag) � > 2 hours @ near � <1 hour outdoors � Mom: -2.00 � Dad: -4.00 � Brother: -2.50
� Plan: Myopia Evaluation 6 months
1. Myopia rates, especially childhood myopia, will become a mainstream health care issue and get attention from those outside our industry.
10. Childhood eye exams and screening guidelines will be revised and lead to better and earlier vision testing for children to identify myopia.
2. FDA will approve devices and/or treatments to stop or slow progression.
3. Asian countries will lead in raising awareness and treatments.
4. Myopia will be recognized and classified as a disease vs. refractive error.
5. The study of genetic markers, will help us understand myopia.
6. A “crisis moment” will happen where the legal risk of not treating will force us to be more proactive in treating myopic children.
7. Companies outside eyecare will recognize the opportunity and bring disruption to the product and/or service side of treatment.
8. Screen time for children will become even more controversial
9. More advanced products will be available for treatment.
� Mykidsvision.org
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� Myopia.care/index � Myopiaprofile.com
� Brien Holden Calculator � Set realistic expectations for treatment � Atropine, MF contacts, Ortho-k all have
around 50%-70% efficacy *depending on studies
› Children will still likely progress depending on age of onset › Which ever method you choose you are
providing evidence based myopia treatment
� Do something! � Assess risk factors � Discuss options › No cookbook approach (yet) › Decide treatment on patients
wants and needs › Actively manage progression
� Enjoy what you do � Don’t dabble in Myopia
Management!
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