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M M yocardial yocardial I I schaemia schaemia N N ational ational A A udit udit P P roject roject Are we replacing good fibrinolytic treatment with poor primary PCI? John Birkhead who has NO CONFLICT OF INTEREST ADVANCED CARDIOVASCULAR INTERVENTION 2010
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Myocardial Ischaemia National Audit Project Are we replacing good fibrinolytic treatment with poor primary PCI? John Birkhead who has NO CONFLICT OF INTEREST.

Jan 04, 2016

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Page 1: Myocardial Ischaemia National Audit Project Are we replacing good fibrinolytic treatment with poor primary PCI? John Birkhead who has NO CONFLICT OF INTEREST.

MMyocardialyocardialIIschaemiaschaemiaNNationalational AAudituditPProjectroject

Are we replacing good fibrinolytic treatment with poor primary PCI?

John Birkhead

who has NO CONFLICT OF INTEREST

ADVANCED CARDIOVASCULAR INTERVENTION 2010

Page 2: Myocardial Ischaemia National Audit Project Are we replacing good fibrinolytic treatment with poor primary PCI? John Birkhead who has NO CONFLICT OF INTEREST.

MMyocardialyocardialIIschaemiaschaemiaNNationalational AAudituditPProjectroject

Primary PCI ; dominant reperfusion therapy in England & Wales

%

Page 3: Myocardial Ischaemia National Audit Project Are we replacing good fibrinolytic treatment with poor primary PCI? John Birkhead who has NO CONFLICT OF INTEREST.

MMyocardialyocardialIIschaemiaschaemiaNNationalational AAudituditPProjectroject

Access to pPCI by hospital Q1 – 2 2009

93

No pPCI 100% pPCI

Hospitals in E&W; n = 223

Page 4: Myocardial Ischaemia National Audit Project Are we replacing good fibrinolytic treatment with poor primary PCI? John Birkhead who has NO CONFLICT OF INTEREST.

MMyocardialyocardialIIschaemiaschaemiaNNationalational AAudituditPProjectroject

30 day mortality (95% CI): thrombolytic treatment and primary angioplasty for STE MI

9.5%

4.5%

Page 5: Myocardial Ischaemia National Audit Project Are we replacing good fibrinolytic treatment with poor primary PCI? John Birkhead who has NO CONFLICT OF INTEREST.

MMyocardialyocardialIIschaemiaschaemiaNNationalational AAudituditPProjectroject

Use of thrombolytic treatment 2007-9

For admission diagnosis STE MI:

• >70 % had lysis < 60 min after call

• 28% pre-hospital (2007)

• door to needle 19 min (IQR 13, 26)

• >80% had lysis (2003-4)

• >60% had angio (2009)

Interval from onset of symptoms to treatment;~ admission diagnosis STE MI

Median 130 min

Page 6: Myocardial Ischaemia National Audit Project Are we replacing good fibrinolytic treatment with poor primary PCI? John Birkhead who has NO CONFLICT OF INTEREST.

MMyocardialyocardialIIschaemiaschaemiaNNationalational AAudituditPProjectroject

30 day mortality; lysis & early angio or rescue vs pPCI

MINAP 2007-9

5%

4.4%4

Page 7: Myocardial Ischaemia National Audit Project Are we replacing good fibrinolytic treatment with poor primary PCI? John Birkhead who has NO CONFLICT OF INTEREST.

MMyocardialyocardialIIschaemiaschaemiaNNationalational AAudituditPProjectroject

Median delays in provision of pPCI

Onset – needle 147 minutes193 min

Page 8: Myocardial Ischaemia National Audit Project Are we replacing good fibrinolytic treatment with poor primary PCI? John Birkhead who has NO CONFLICT OF INTEREST.

MMyocardialyocardialIIschaemiaschaemiaNNationalational AAudituditPProjectroject

MINAP data

Reperfusion Rx for STEMI (England & Wales) 2003-9

33% too late16% ECG ineligible17% elective11% bleeding risk0.5% hypertension

Page 9: Myocardial Ischaemia National Audit Project Are we replacing good fibrinolytic treatment with poor primary PCI? John Birkhead who has NO CONFLICT OF INTEREST.

MMyocardialyocardialIIschaemiaschaemiaNNationalational AAudituditPProjectroject

Distribution by ageband of reperfusion treatment2007-9

MINAP data

Page 10: Myocardial Ischaemia National Audit Project Are we replacing good fibrinolytic treatment with poor primary PCI? John Birkhead who has NO CONFLICT OF INTEREST.

MMyocardialyocardialIIschaemiaschaemiaNNationalational AAudituditPProjectroject

Comparative use of reperfusion treatment by ageband 2007-9

Page 11: Myocardial Ischaemia National Audit Project Are we replacing good fibrinolytic treatment with poor primary PCI? John Birkhead who has NO CONFLICT OF INTEREST.

MMyocardialyocardialIIschaemiaschaemiaNNationalational AAudituditPProjectroject

30 day mortality following lysis + rescue/early angio vs pPCI

Page 12: Myocardial Ischaemia National Audit Project Are we replacing good fibrinolytic treatment with poor primary PCI? John Birkhead who has NO CONFLICT OF INTEREST.

MMyocardialyocardialIIschaemiaschaemiaNNationalational AAudituditPProjectroject

Are we replacing good fibrinolytic treatment with poor primary PCI?

Conclusions

Organisation: ?+Equity of access ? -

Page 13: Myocardial Ischaemia National Audit Project Are we replacing good fibrinolytic treatment with poor primary PCI? John Birkhead who has NO CONFLICT OF INTEREST.

MMyocardialyocardialIIschaemiaschaemiaNNationalational AAudituditPProjectroject