MYELOGRAPHY and CNS Exams using MRI & CT Spring 2011
Meninges
• Membranes that enclose the brain and spinal cord
– Dura Mater- outer layer
– Arachnoid = middle layer
– Pia mater = innermost layer
– Subarachnoid space = wide space between arachnoid and pia mater
Why is Subarachnoid space so valuable?
– Wide space between arachnoid and pia mater• __________________________________• __________________________________• __________________________________• __________________________________
CSF Information
• Total adult CSF volume is ________ ml– ________intracranial– ________spinal
• Adult opening pressure is normally _______cm fluid– __________ abnormal– Young adults slightly higher ____________
Spinal Cord Diameter
• AP diameter is _______mm through C7• C7 to conus medullaris is ________mm• At conus it is __________________mm
• Cord size is considered abnormal if it is over __________mm or under _________mm
Myelography
• General term applied to the radiologic examination of the CNS structures situated in the vertebral canal
• Requires contrast introduction into the subarachnoid space by spinal puncture
• Puncture made at L2-L3 or L3-L4 space– May also be introduced into cisterna magna at C1 and
occipital bone
Contrast Precautions
• Verify it is the correct contrast– Non-ionic iodinated contrast
• Omnipaque or Isovue– Correct concentration
• 180 and 300 common
• Check ______________________
• Keep contrast vial in room until procedure is complete
Room should be prepared by RT before patient arrival
1)________________________
2) _______________________
3) _______________________
4) _______________________
5) _______________________
FOOTBOARD
SHOULDERPADS
Hand grips
Additional items• Blankets• Sterile towels• Sodium bicarbonate (if not in tray)• Non-ionic iodinated contrast media• Sterile gloves for DR• Shields for PT, DR, anyone else in room, and yourself• Varying sizes of spinal needles and needles• Extra syringes and tubing • Cleaning liquid
PRE- Procedure :Myelography• Premedication rarely needed
• Patient should be well hydrated
• Check orders, obtain history, labs results (if necessary), and previous exams
• Informed consent:– Risks, benefits alternatives
• Procedural details, including table movement and sensations should be explained, and get pt into a gown
Contraindications and Considerations
• PT < 15.0 seconds– Preferable to reschedule exam if below 15
• Platelets >100,000– If below 50,000 a platelet transfusion may be indicated
before procedure• Heparin stopped 4 hours before
– Can be restarted 2 hrs after procedure– Usually given as IP
• Coumadin stopped 3-4 days before – Usually OP– Labs usually indicated
Radiation Safety
• Have shields
• Question– LMP – Possibility of pregnancy
• Use cardinal rules– ________________– ________________– ________________
• ALARA– Use pulse if possible– Save the last image on screen when possible
Prone & Lateral Flexion
• Prone– ____________________
• Lateral flexion is not commonly used– ____________________
____________________
Myelography
• Local anesthesia given at puncture site
– ______________________________
• Spinal needle inserted – __________________________________
• Labs– _________________________________
• Contrast injected and needle removed– _______________________ ml
• The use of gravity– ________________________________
• Spot images taken as needed
Spot Films
• Central ray vertical or horizontal using CR or film screen cassettes
• Images are taken at– Site of blockage– Level of distortion
• If conus medullaris is area of concern:– Lay pt supine– Central ray at T12- L1– Use 10x12 cassette and collimate tightly
Ventricles and Myelography
• Acute Extension of neck– Why?
• What happens if contrast enters ventricles?• ______________________________________
____________________________________
Myelography
• Usually performed as outpatient basis
• Common for CT myelography (CTM) to be used with conventional Myelogram
• MRI often used instead
• Myelography and CTM still used for patients with contraindications for MRI– Pacemakers and metal fusion rods
Post procedure: Myelography1) _______________________________________
2) _______________________________________
3)________________________________________
4)________________________________________
5)________________________________________
6)________________________________________
More Severe Complications
• Nerve root damage• Meningitis• Epidural abscess• Contrast reaction (anaphylactic shock)• CSF leak• Hemorrhage
Treatment for Spinal Headache
• Initial treatment
1)
2)
3)
4)
• Persistent headache– Fever occurs
• ___________________• May be indicative of
___________________
• ___________________– Beyond 48 hrs
• No Fever – 24 hrs if severe– No fever
Blood Patch
1) Clot will occur over hole
2) ___________________
3) ___________________
4) ___________________
CTM
• Performed after _____________________________
• Can be performed at _____ level of vertebral column
• Multiple slices taken _________________________– Gantry is ________________________________________
• Windowing allows for density and contrast changes
• Can obtain images with _______ amounts of contrast– Can be done _______________ hours after initial injection
MRI of Spinal Cord and CSF flow• Non-invasive
– Provides anatomic detail of brain, spinal cord, intravertebral disc spaces, and CSF within subarachnoid space
– Does not require intrathecal injection
– Does not have bone artifacts
MRI basics
• T1 & T2 images can be taken– Head coil for brain– Body coil and surface coil form spine
• IV contrast can be used to enhance tumor– Gadolinium
Preference of MRI
• MRI is the preferred modality for middle and posterior cranial fossa of brain.– In CT these structures are obscured by bone
artifacts
• Spinal cord– Allows direct visualization of spinal cord, nerve
roots, and surrounding CSF– Can be done in various planes– Aid in diagnosis and treatment of neurodisorders
Usefulness of MRI
• Assessing demyelinating disease– Such as MS
• Spinal cord compression
• Postradiation therapy changes of spinal cord tumors
• Herniated disks
• Congenital abnormalities of vertebral column
• Metastatic disease
• Paraspinal masses
MRI and Brain imaging
• Middle and posterior fossa abnormalities• Acoustic neuromas• Pituitary Tumors• Primary and metastatic neoplasms• Hydrocephalus• AVM’s• Brain atrophy
Not valuable for diagnosing:
• Osseous bone abnormalities of skull
• Intracerebral hematomas
• Subarachnoid Hemorrhage
– CT preferred for these 3 illnesses
CT of Brain basics
• Useful for demonstrating size, location and configuration of mass lesions and surrounding edema
• Assessing cerebral ventricle or cortical sulcus enlargement
• Shifting of midline structures caused by mass lesions, cerebral edema, or hematoma
Indications for Pre and Post contrast Imaging using CT
• Suspected Neoplasms• Suspected metastatic disease• Arteriovenous malformation (AVM)• Demyelinating disease (MS)• Seizure disorder• Bilateral isodense hematomas
Indications for Brain scans without Contrast media
• Dementia
• Craniocerebral trauma
• Hydrocephalus
• Acute infarcts
• Post evacuation follow up of hematomas
CT Brain imaging
• Most often Axial orientation• Gantry 20-25 degrees to OML
– Allows lowest slice to provide an image of both the upper cervical, foramen magnum, and roof of orbit
• 12-14 slices – 8-10 mm slices– 3-5 mm slices through post fossa– Depending of PT size– Slice thickness
CT Brain imaging (cont)
• Coronal imaging
– Helpful in evaluation of• Pituitary gland• Sella turcica• Facial bones• Sinuses
CT: Modality of choice
• Modality of choice for the following”
– Hematomas– Suspected aneurysms– Ischemic or hemorrhagic
strokes– Acute infarcts
• Used as initial diagnostic modality for:
– Craniocerebral trauma
CT of Spine
• Useful in diagnosis of vertebral column hemangiomas and lumbar spine stenosis
• Often used post-trauma to assess Axis and Atlas fractures and for better demonstration of C7-T1
• Clearly demonstrates size, number and locations of fracture fragments of C, T and L spine.
Surgery Applications of CT imaging
• Greatly assists surgeons in distinguishing neural compression by soft tissue from compression by bone
• Post-op– Useful in assessing outcome of surgical procedure
MRI vs. CT
• MRi superior to CT for imaging of posterior fossa– CT has artifacts from bone– MRI is free from bone artifacts
• MRI has inability to image calcified structures. CT is superior for calcifications
• MRI can detect cerebral infarction earlier than CT.
• Both modalities provide similar information on subacute and chronic strokes
Diskography and Nucleography
• Radiologic exam of individual intervertebral disks– 1)
– 2)
– 3)
– 4)
Vertebroplasty
• Interventional radiology procedure to treat compression fractures or other pathologies in the vertebral bodies
• Used when _______ treatment does not work– Used when _______ pain does not improve over a
number of _____________________ of treatment
Complications of Vertebroplasty and Kyphoplasty
• Most common: _________________________
• Less common: _________________________– Death
Success of Vertebroplasty and Kyphoplasty
• Success is measured by___________________________________
• Can help reduce ___________ and restore________________________________
• With Kyphoplasty there is a 80-90% success rate
Vertebroplasty and Kyphoplasty clips
• http://www.unikron.com/tools/play/play_display.cgi?speed=hi&id=good_samaritan2
• http://www.or-live.com/StJoseph/1319/
Considerations of Pain Management Interventional Procedures
• Stop NSAID 3 days prior to procedures
• With Facet injections no pain relievers 4 hours prior to procedure
• Takes 3- 10 days for full results to manifest
• Done when conventional treatment has not helped
Epidural• Used to treat pain as a result of and injured disk affecting
spinal nerves– _________________________________________________________
• Done under fluoroscopy with PT awake– _________________________________________________________– _________________________________________________________– _________________________________________________________
• Complications– Most common:_______________________– ___________________________________– ___________________________________
Facet Injections
• Indications:1)2)
• Causes of pain include:– ____________________
____________________
• Awake under fluoro1)
2)
• Complications1)2)3)4)
Side effects of Steroids
• Fluid retention
• Weight gain
• Mood swings
• Increase in blood pressure
• Usually temporary
Spinal Cord Stimulation
• Delivers low voltage electrical stimulation to the spinal cord– 1)– 2)
• Done in two stages– 1)– 2)
Trial and Permanent Placement
• Done in OR– ________________________
________________________
• _______________________
• ______________________________________________
• If trial period helps:– ________________________
• Contains generator with battery (some are rechargeable)– Periodically battery is
replaced
• Others have transmitters & generators
Generators only vs. Generators with Transmitters
• SCS with generators inside the body must be replaced in OR– ____________________
– ____________________
• SCS with transmitters can also be one time use or rechargeable– ____________________
____________________
SCS Indications, Benefits & Risks
• Indications:– Chronic pain associated with:
• Neuropathic pain• Failed back surgery
syndrome• Arachnoiditis• Certain vascular disease
• Benefits1)
2)
3)
• Risks1)2)3)4)5)
Radiofrequency Neurolysis
• Uses high frequency radio waves to produce a heat lesion1)2)3)
• Done under fluoro in OR
Radiofrequency Neurolysis• Helps for_____ months
• ______of PT’s get relief
• Takes about_________ minutes
• Can be repeated if pain returns
Radiofrequency Neurolysis
• PT is__________________ and ______ sedated• Local anesthetic injected
– 1)– 2)
• Once PT confirms this , they are sedated more– 1)– 2)