My folding vanessa morales ospina

“COWCATCHER” ENZYME FIXES SINGLE-STRAND DNA AND PROTOCELLS MAY HAVE FORMED IN SALTY SOUP.  

VANESSA MORALES OSPINA

MEDICINE STUDENT

3RD SEMESTER

FOLDING

FOLDING

INTRODUCTION

• For years the DNA molecule has been the focus of genetic and molecular studies

• This molecular structure when performing its functions is regulated by highly organized processes to ensure their proper development and function

“ COWCATCHER” ENZYME FIXES SINGLE- STRAND DNA

AUGUST 2, 2013

“ COWCATCHER” ENZYME FIXES SINGLE- STRAND DNA

“Zipper” DNA

• To understand the UTMB researchers' work, it helps to picture DNA strand separation during replication as analogous to the opening of a zipper. As the "zipper" opens, it exposes strings of four uniformly spaced bases attached to each single strand of DNA.

“ COWCATCHER” ENZYME FIXES SINGLE- STRAND DNA

Nei endonuclease VIII-like 1  ( NEIL 1).

• The group of scientists from UTBM focused their study on the mechanisms of the enzyme NEIL 1 found in the single-stranded DNA and the replication complex.

“ COWCATCHER” ENZYME FIXES SINGLE- STRAND DNA

Genome

• This enzyme is very important because in the cell division, controls and

regulates many processes, also maintains the integrity of the

genome.

OBSERVATION

This news seems to me very useful and significant as

showing a responsible for repairs in our genetics also seems very important for the medical use because

with the help of this enzyme and biotechnology can be

implemented the elimination of genetic

mutations that affect our patients

PROTOCELLS MAY HAVE FORMED IN A SALTY SOUP

AUGUST 2, 2013

PROTOCELLS MAY HAVE FORMED IN A SALTY SOUP

Cell

• This news question on a evolutionary enigma : a cell doesn't function without a cell wall, but how does the cell wall form if there is no cell?

PROTOCELLS MAY HAVE FORMED IN A SALTY SOUP

Protein synthesis

• In a solution containing the biomolecules that are

normally locked in a cell (like DNA, RNA, enzymes, proteins) these large

biomolecules clustered together spontaneously when

the salt concentration was increased.

PROTOCELLS MAY HAVE FORMED IN A SALTY SOUP

• "When biomolecules are packed together, we expect reactions to proceed much faster.

• A functioning cell must be entirely correct at once, in all its complexity,“

• “ We are now closer to Building a synthetic cell Than anyone ever before us” said the professor Huck.

OBSERVATION

This news seems very interesting because it answers

questions that has many people we have come and to

seek an explanation, I think the Professor Wilhelm Huck

essentially sought to show the cell, in medicine this is very

valuable for the development of these investigations can help prevent and improve

many diseases using synthetic cells to regenerate tissues,

organs etc.

MEDICAL UTILITY

MEDICAL UTILITYPROTOCELLS MAY HAVE FORMED IN A

SALTY SOUP

• Treatments such as synthetic cell development if it can implement this, it would mean the disappearance of malignant cell regeneration that can invade the proliferative disease patients.

MEDICAL UTILITY“ COWCATCHER” ENZYME FIXES SINGLE-

STRAND DNA

Is very important the concept of enzyme NEIL 1 level riders because of genetic diseases could invent and develop processes either from the womb to born persons, improving gene disorders can show serious affecting the morphology and neurological capacity

MEDICAL UTILITY

• These findings actually are significant in the race that is always in favor of the health and welfare of people.

BIBLIOGRAPHY

• Martínez S, lina maría. Biología molecular. 7 ed. Medellín: UPB. Fac medicina, 2012. 74-84 p.

• Radboud University Nijmegen (2013, July 2). Protocells may have formed in a salty soup.[On Line] ScienceDaily. Retrieved August 2, 2013, from http://www.sciencedaily.com /releases/2013/07/130702100115.htm.

• University of Texas Medical Branch at Galveston (2013, July 29). 'Cowcatcher' enzyme fixes single-strand DNA. [On Line]ScienceDaily. Retrieved August 2, 2013, avalaible online: from http://www.sciencedaily.com /releases/2013/07/130729161751.htm.

THANKS.