MMC, VICC & TSU: Partners in Eliminating Cancer Health Disparities Meharry and Vanderbilt become one of the first Cancer Partnerships supported by the NCI U54 grant mechanism MVTCP continues to grow. The partnership has submitted a competitive renewal and will expand training to high school students. TSU becomes a full partner and the MVTCP becomes the second Triad in the PACHE. TSU brings new investigators and undergraduate students. Tennessee State (TSU) joins the MVCP as a collaborator, expanding the partnerships research into Community Engaged Research Meharry and Vanderbilt form a partnership in response to a supplement to the CCSG grant. Our Cancer Partnership has matured and developed successful collaborative interactions based on excellence, true reciprocity, and mutual benefit. As a triad, we aim to amplify the cancer research capabilities in the greater Nashville community, improve outcomes in the diagnosis and treatment of cancer in minority and underserved communities, minimize measurable disparities among minority populations, and fortify collaborations among the partners. During the past 5 years, we have made significant progress toward achieving our mission through: 1) recruiting 6 new faculty members; 2) training 7 PhD and MPH candidates at MMC and TSU; 3) training 4 oncology fellows at MMC/ VICC; 4) providing summer cancer research experience to 18 undergraduates at TSU and 22 medical students at MMC and VICC; and 5) increasing clinical trials access. Our clinical trials core accrued 350 patients (57% African American) and increased the number of open clinical trials in both cancer treatment and control studies (50% over two years). Our program evaluation structure includes the monitoring by the Internal Advisory Committee, the Program Steering Committee, and the As we look ahead, we plan to: 1. Fund state-of-the-art research projects to increase and stabilize the competitive cancer research capability of MMC and TSU; 2. Increase the cancer disparities research portfolio at VICC; 3. Expand cancer research education program to include high school students; 4. Implement a hybrid outcomes-logic-model and a pure outcomes-based process to evaluate the Partnership’s progress; 5. Enhance clinical trials access for minority populations served by Nashville General Hospital (NGH)/MMC. Lourdes Estrada, Ph.D. 1* , Ketia Barnes, B.S. 2* , David E. Danner, J.D. 3 , W. Wayne Green, B.S. 2 , Samuel E. Adunyah, Ph.D. 2 , Baqar A. Husaini, Ph.D. 3 , Philip E. Lammers, M.D. 2 , Harold L. Moses, M.D. 1 , Ann Richmond, Ph.D. 1 , Margaret Whalen, Ph.D. 3 *Presenting Co-authors; 1 Vanderbilt Ingram Cancer Center, Nashville, TN; 2 Meharry Medical College, Nashville, TN; 3 Tennessee State University, Nashville, TN Acknowledgments Education & Training Future Directions Clinical Trials Community Outreach Introduction Partnership History Activities Engagement with populations affected by cancer health disparities through Community Advisory Board (CAB), Teen and Parent (TAP) Committee, Cancer Survivorship Committee, listserv and outreach to underserved communities. Provision of tangible support to MVTCP-funded and emerging projects (e.g., expert consultation, recruitment, protocol development & review), community organizations and coalitions, and the NCI National Outreach Network in cancer disparities efforts. Mentoring students and trainees in Community Engaged Research and culturally-appropriate outreach strategies. Administrative supplement to expand evaluation of HPV vaccine social marketing intervention Hosting of two radio health programs reaching African American and Hispanic audiences, providing 100 hours of health information programming and cancer researcher guest interviews each year. Accomplishments Awarded NCORP grant partnership with Memphis Baptist Healthcare System Successful Alliance Cooperative Group Site Audit and WFU Site Audit Nashville General Hospital was awarded Commission on Cancer 3-Year Accreditation with a Commendation for Clinical Trials Program and Accruals Hired a 2nd medical oncologist, Dr. Robin Jacob from Howard University and a surgical oncologist, Dr. Sandeep Anantha from Michigan This material is based upon work supported by the National Cancer Institute PACHE program grant numbers 5U54CA163069 (MMC), 5U54CA163072 (VICC), and 5U54CA163066 (TSU). Research Activity Recruitment Basic Science Population Science Clinical Science Anil Shanker, MS, PhD (MMC) Rebecca Selove, MPH, PhD (TSU) Philip Lammers, MD, MSCI (MMC) Jamaine Davis, PhD (MMC) Hilary Tindle, MD, MPH (VICC) Sandeep Anantha, MD (MMC) 0 50 100 150 200 250 300 2011 2012 2013 2014 2015 2016 Cancer Control Studies Cancer Treatment Trials MVTCP Clinical Trials Core Enrollment to Clinical Research 2011-2016 Caucasian African-American Hispanic Other 2011 - 2015 Full Projects: Supported a total of four (4) full projects - two for three years on breast cancer and prostate cancer and two for two years on cancer survivorship and lung cancer . Pilot Projects: Supported a total of two (2) pilot projects - one for three years on HPV vaccine and the other for two years on breast cancer. Shared Resource Cores: Support four (4) Shared Resource Cores: Biostatistics Core Translational Pathology Core Clinical Trials Core Community Outreach Core Grants: Awarded over 20 grants including 3 R01s, 2 SC1s, and 2 R21s Publications: 150+ peer-reviewed publications Meharry (MMC) - Vanderbilt (VICC) - Tennessee State (TSU) Cancer Partnership Drs. Pam Hull (l) and Lourdes Estrada from VU on Progress & Wellbeing (Progreso y Bienestar) on La Nueva Activa 1240 AM Training Opportunities Undergraduates: Summer Research Experience; Introduction to Cancer Biology Course, Mentored Behavioral Science Training in Cancer Disparities Masters of Public Health Students: Summer Research Experience; Graduate Internship with Community Outreach Core Doctoral Students: Pre-doctoral training support Medical Students: Summer Research Experience Postgraduates: Oncology Fellowship with Clinical Trials Core