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MEDICAL IMAGING TECHNOLOGY Vol. 34 No. 1 January 2016 3
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図 6 VBM解析例:健常者における年齢と灰白質との負の相関.
2)http://www.brain-development.org/
Med Imag Tech Vol. 34 No. 1 January 2016 7
Voxel-based Morphometry Using Structural MRI
Fumio YAMASHITA *1
*1 Iwate Medical University
Voxel-based morphometry (VBM) is a widely-used image analysis technique for brain morphometry using struc-tural MR images. VBM is advantageous in that it can evaluate the whole brain objectively, without laborious and time-consuming manual intervention. It has become a major analysis technique since it was firstly applied to psycho-logical and neurological diseases accompanying cerebral atrophy, and is now also applied to cognitive sciences fields. In this paper, VBM is summarized focusing on two essential algorithms, segmentation and normalization, including cautions and applications.Key words: Voxel-based morphometry, MRI, Segmentation, Anatomical normalizationMed Imag Tech 34(1): 3-7, 2016