425.702.6365 or 888.246.6373 I www.chondrex.com | 1.0 Mouse Arthritis Scoring System # 1 Observe three joint types for scoring A: Interphalangeal joint B: Metacarpophalangeal joint C: Carpal and tarsal joint Normal: Score 0 Score 1 One joint type (A, B, and C) has redness and swelling. Score 2 Two joint types (A, B, and C) have red- ness and swelling. Score 3 All three joint types have redness and swelling. Score 4 Maximal redness and swelling of the entire paw leads to the disappearance of anatomical definition Front Paws Hind Paws A B C B C A A C A B C A A C B A C B