A system of, Molecular dynamics synchronised Manipulator to repair Biomolecules It’s a dream comes true on Healthcare Jayakar Johnson Joseph, Johnsons Medicom (P) Ltd. www.clustermatteruniverse .net
Aug 07, 2015
A system of,Molecular dynamics synchronised Manipulatorto repair Biomolecules
It’s a dream comes true on Healthcare
Jayakar Johnson Joseph, Johnsons Medicom (P) Ltd.
www.clustermatteruniverse.net
Requires Further
developments
Inadequate Healthcare modalities
To proceed:Molecular repairing
that includes Genomic repairing
Thus proposes: In-depth analysis
on Molecular dynamics & Manipulation techniques
Demerits of existing Healthcare modalities & Proposed solutions
Therapeutic actions and Side effects are defined only by statistical analysis
Metabolic pathways are assigned only by the detection of molecules in specific localities
Therapeutic
Uncertainty
Inconclusive metabolic pathways
Regulatory Proteins
Poly ADP Ribose
Polymerase
Intentions & main objectives
Protein Synthesis
Apoptosis
Targeted molecules in Malignancy
Field of this work and applied field
Thanks to: Institute for System Biology
Field of work:System Biology
Field of Application:
Healthcare
Eigen-rotational Clusters of
String-matter Universe
This system is developed from the paradigm of:
According to this paradigm, a String-matter segment is equivalent to a particle with field.
Thus the notation of incident on eigen-rotation of a string-segment at the observer/detector locality provides
more information than with the expression of incident beam of particles at the observer/detector locality.
Innovation behind this system of instrumentations
This implies a notation of dual wave lengths on wave propagation and describes the evolution of discrete cyclic-times in holarchy.
A generic wave mechanics is defined to resolve the paradoxes on wave particle duality and wave function collapse, in particle scenario.
Intended to Manipulate the molecular
dynamics of the Target-Source
to repair biomolecules
Objectives
To explore and to study Molecular dynamics in Biological
Systems
Therapeutic Application
How this instrumentation differs in therapeutics ?
Classical
Target of application is locality based
Collateral damage is inevitable
MDSM
Target of application is molecule and element based
Collateral damage is minimized
Some Functional Units of the
System1. Targeted Bio-molecular source retainer for NMR
alignment
2. Tracer molecules delivering Unit
3. Multiple Pyramidal Arrays of detectors
4. Tetrahedral-mesh based Morphometric image processing
5. Data mining Unit
6. Knowledge-Based Fuzzy Controller
7. Unit for System tuning and Configuring
8. Virtual molecular dynamics manipulation unit
9. Synchronisation unit
10.
Matter injecting unit
11.
Energy injecting unit
12.
External Data and commands networking Hub
Classification of Instrumentation
In vitro specimen study
In vivo animal testing
Therapeutic Applications
3 levels of
operations
Tetrahedral-mesh based Morphometric image processing
• Labelled data from detector arrays
• Data decomposition
• Processing of Tetrahedral-mesh
Knowledge-Based Fuzzy Controller
KB Fuzzy Controller
Manipulation Benchmark
Synchronization
Extracted data
System Tuning
Virtual molecular-dynamics Manipulator
Alters
Data from Detector
array
Synchronization with Phase
shift
Anti-phase Synchronizatio
n
In-phase synchronization
Synchronising Unit
Principles used for Synchronization
No Synchrony
Thanks to: Dr. Arkady Pikovsky & Dr. Michael Rosenblum
Synchronising UnitTriad of Synchronisation
Incident at
detection point
Delivery of Matter to event
point
Delivery of Energy to
event point
In external reference
time, t
In
Discrete-tim
e
In Discrete-time
In Discrete-time
Matter injecting unit
Matrix-assisted laser desorption/ionization
(MALDI)
Electrospray ionization (ESI)
Techniques Applied
Individual or in combination
Applications : Direct
In vitro Bio-molecular dynamics
study
In vivo Bio-molecular dynamics study in
animals
New therapeutic modality for Humans
Further Applications in Basic Research
Data by this system
Scaling of Eigen-rotational string-
matter segments in Planck scale
Defining new properties for
Chemical elements
Physics
Chemistry
Future updates of MDSM System
Sound waves
Micro-lithotripsy
Ultra Sound tuning of implants
X-ray
On analysi
s
- ray
On analysi
s
Proposed Inclusions