Molecular Biology Molecular Biology of the Gene of the Gene PART 2 PART 2 Debbi Ann Morrissette Debbi Ann Morrissette Graduate Student Researcher Graduate Student Researcher Laboratory of Molecular Laboratory of Molecular Neuropathogenesis Neuropathogenesis University of California, University of California, Irvine Irvine
Molecular Biology of the Gene PART 2. Debbi Ann Morrissette Graduate Student Researcher Laboratory of Molecular Neuropathogenesis University of California, Irvine. PART 1. Structure of DNA DNA Replication DNA vs. RNA. PART 2. Flow of Genetic Info Mutations Cloning Differentiation - PowerPoint PPT Presentation
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Molecular Biology Molecular Biology of the Geneof the Gene
PART 2PART 2Debbi Ann MorrissetteDebbi Ann Morrissette
Graduate Student ResearcherGraduate Student ResearcherLaboratory of Molecular Laboratory of Molecular
NeuropathogenesisNeuropathogenesisUniversity of California, IrvineUniversity of California, Irvine
PART 1PART 1
Structure of DNAStructure of DNA DNA ReplicationDNA Replication DNA vs. RNADNA vs. RNA
PART 2PART 2 Flow of Genetic InfoFlow of Genetic Info MutationsMutations CloningCloning DifferentiationDifferentiation X Chromosome InactivationX Chromosome Inactivation
The 2 Main Functions of The 2 Main Functions of DNADNA
Passing genetic information to Passing genetic information to daughter cellsdaughter cells Through DNA replicationThrough DNA replication
Directing the synthesis of proteinsDirecting the synthesis of proteins Through Through transcriptiontranscription of the DNA code of the DNA code
and and translationtranslation of the nucleotide code of the nucleotide code into an amino acid sequenceinto an amino acid sequence
tRNA = transfer RNA tRNA = transfer RNA ““The Translator”The Translator”
G A A U UG U U A G
TranscriptioTranscriptionn
TerminationTermination RNA reaches the RNA reaches the terminatorterminator sequence sequence on the DNA strand on the DNA strand and releases from and releases from the DNAthe DNA
along the DNA strand along the DNA strand adding complementary adding complementary RNA nucleotides to make RNA nucleotides to make the mRNA strandthe mRNA strand
Following Following transcription, the transcription, the “message” is “message” is brought from the brought from the nucleus to the nucleus to the cytoplasm.cytoplasm.