This document is posted to help you gain knowledge. Please leave a comment to let me know what you think about it! Share it to your friends and learn new things together.
Transcript
7
CONTENTSMOLECULAR BIOCHEMISTRY .........................13Chromatin Structure ___________________________________ 14Heterochromatin ______________________________________ 15Euchromatiin _________________________________________ 15DNA Methylation ______________________________________ 15Histone Methylation ___________________________________16Histone Acetylation ___________________________________16Nucleotides __________________________________________16High Yield Points ______________________________________16High Yield Points ______________________________________ 17De novo Pyrimidine & Purine synthesis __________________18Orotic aciduria ________________________________________ 19Adenosine deamine deficiency _________________________20Lesch_Nyhan Syndrome _______________________________20DNA Replication ______________________________________ 21Points to remember ___________________________________23Mutations in DNA _____________________________________24Start and stop codons _________________________________26High yield points ______________________________________26Types of RNA _________________________________________27Introns vs exons _______________________________________27Protein synthesis ______________________________________28Points to Remember ___________________________________29
LIPIDS .........................................................................96Fatty acid metabolism _________________________________97LDL Vs HDL ___________________________________________97Specialised products of cholesterol ____________________ 98BUN:creatinine elevation causes ______________________ 98Apolipoprotein ________________________________________99
Sites of oxidation of Fatty Acids ...................100Sites of metabolic pathway .............................101Rate limiting enzymes ......................................102
12
MISCELLANEOUS ............................................... 103Carbon monoxide: electron transport chain target _______104Serum protein electrophoresis ________________________104BUN:creatinine elevation:causes _______________________105X-Linked Dominant disorders _________________________105Non-gap acidosis:causes _____________________________106Anion gap causes ____________________________________106Metabolic acidosis:causes ____________________________107Points to remember __________________________________107