PROGRAMME MANAGERS’ TRAINING COURSE FOR NTDS TARGETED FOR CONTROL OR ELIMINATION BY PREVENTIVE CHEMOTHERAPY INTERVENTIONS PROGRAMME MANAGERS’ TRAINING COURSE FOR NTDS TARGETED FOR CONTROL OR ELIMINATION BY PREVENTIVE CHEMOTHERAPY INTERVENTIONS Module 2. NTD Strategies Session 2. Preventive Chemotherapy Strategy
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Module 2. NTD Strategies - World Health Organization · Module 2. NTD Strategies Session 2. Preventive Chemotherapy Strategy What Is Preventive Chemotherapy (PC)? • Preventive chemotherapy
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PROGRAMME MANAGERS’ TRAINING COURSE FOR NTDS TARGETED FOR CONTROL OR ELIMINATION BY PREVENTIVE CHEMOTHERAPY INTERVENTIONS
PROGRAMME MANAGERS’ TRAINING COURSE FOR NTDS TARGETED FOR CONTROL OR ELIMINATION BY PREVENTIVE CHEMOTHERAPY INTERVENTIONS
Module 2. NTD Strategies
Session 2. Preventive Chemotherapy Strategy
PROGRAMME MANAGERS’ TRAINING COURSE FOR NTDS TARGETED FOR CONTROL OR ELIMINATION BY PREVENTIVE CHEMOTHERAPY INTERVENTIONS
• Preventive chemotherapy (PC) is a public health intervention based on the large-scale administration of safe drugs, either alone or in combination, against selected Neglected Tropical Diseases.
• PC is recommended by WHO as one of the key public health interventions for:
*Clonorchiasis and opisthorchiasis
LF FBT* Schisto STH Trachoma Oncho
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PROGRAMME MANAGERS’ TRAINING COURSE FOR NTDS TARGETED FOR CONTROL OR ELIMINATION BY PREVENTIVE CHEMOTHERAPY INTERVENTIONS
When PC is delivered with effective medicines, with high coverage at regular interval, it can reduce overall parasite/bacterial load and reduce/interrupttransmission of the targeted NTDs in entire communities.
When PC is given early in life, it can prevent development of chronic consequences of morbidity related to these infections and improve health, education, economic status and social well being of affected communities.
This PC approach is an essential component of the strategy for sustained reduction of transmission and ultimately elimination of LF, onchocerciasis, schistosomiasis and trachoma.
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PROGRAMME MANAGERS’ TRAINING COURSE FOR NTDS TARGETED FOR CONTROL OR ELIMINATION BY PREVENTIVE CHEMOTHERAPY INTERVENTIONS
Integrating Treatment For Multiple Diseases as a PackageBecause target age groups overlap among different diseases, medicines can be delivered as a package together to the same target population.
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NTD MedicinePre-SAC
(2 - 5 yr old)SAC
(5 - 14 year old)Adults
(>15 yr old)
LF DEC + ALB X X X
Oncho IVE X X
STH ALB or MBD X X
Schistosomiasis PZQ X X (only at-risk adults)
Clonorchiasis,Opistorchiasis
PZQ X X
Trachoma AZM X X X
PROGRAMME MANAGERS’ TRAINING COURSE FOR NTDS TARGETED FOR CONTROL OR ELIMINATION BY PREVENTIVE CHEMOTHERAPY INTERVENTIONS
Integrating PC-related Activities Across Different Disease ProgrammesBecause most of activities are common among different disease programmes, they can be delivered together for multiple diseases.
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Activities LF STH SCH FBT TRA
Advocacy √ √ √ √ √
Mapping √ √ √ √ √
Training √ √ √ √ √
Social mobilization √ √ √ √ √
Drug logistics √ √ √ √ √
Drug distribution Pre-SAC √ √ √
SAC √ √ √ √ √
Adults √ (√) √ √ √
M&E √ √ √ √ √
Coordination for other
interventions
Vector control √ √ √
Water and sanitation √ √ √ √ √
Case management √ √ √ √
PROGRAMME MANAGERS’ TRAINING COURSE FOR NTDS TARGETED FOR CONTROL OR ELIMINATION BY PREVENTIVE CHEMOTHERAPY INTERVENTIONS
• PC is a public health intervention aimed at controlling morbidity and transmission of targeted NTDs.
• PC focuses on regular delivery of drug packages to as many people in need.
• PC challenges NTD programme managers to i) integrate and coordinate between disease specific programmes and partners, ii) procure sufficient quantities of quality drugs, to implement drug distribution with good coverage in the most cost-effective way, iii) monitor and ensure drug safety.