8/16/2019 Misoprostol vs Metergin http://slidepdf.com/reader/full/misoprostol-vs-metergin 1/20 Randomized comparative study of oral misoprostol with intravenous methyl ergometrine in prevention of postpartum haemorrhage in cases high risk for postpartum haemorrhage Department of Obstetrics & Gynaecology, ESIC Medical College, Kalaburagi, Karnataka, India Received: 17 January 2016 Revised: 17 e!ruary 2016 "ccepted: 22 e!ruary 2016 "isha #umera$ %udha &iradar 'erure
This document is posted to help you gain knowledge. Please leave a comment to let me know what you think about it! Share it to your friends and learn new things together.
Misoprostol, a synt!eticprostaglandin E2 analogue, $!ic!
$as basically used for t!e treatmentof gastric ulcers and !as action o"ert!e uterine myometrium causing t!euterus to contract and t!us can beused for pre"ention of postpartumbleeding'
potential bene#ts including rapid absorption,ease of administration 3oral, rectal, sublingual4
does not re5uire any trained personnel and can
be administered by traditional birt! attendants,cost e6ecti"eness and no special condition for
t!e storage and transport,!as a s!elf%life of se"eral years and t!us it
pro"es to be a suitable uterotonic agent for usein t!e prop!ylactic management of t!ird stageof labour especially in resource%poor set%up inde"eloping countries
e"en in presence of s!i"ering $!ic! is aserious side e6ect but self%limiting $it!oral misoprostol o6ers se"eral ad"antages s!elf%life of se"eral years,
stability at !ig! temperatures 3i'e', it does notre5uire refrigeration4 and oral administrationi'e',
it does not re5uire needle or syringe $!ic! is ama?or ad"antage in t!e era of )I@ and)epatitis 0'