Mibbi workshop-isa-project

MI-compliant ISA configurations

Philippe Rocca-SerraOxford University, Oxford, UK

MIBBI workshop, December,1st-3rd 2010, Germany**(...and Heathrow airport)

[email protected]

mage-tab | pride-ml | sra-xml | others

ISA infrastructure overview

IISAcreator: a tool for reporting studies

structured reports...declaring variables

Making sense: ontology term tagging

Not just microarray data....

Telling more about experimental design

A focus on standards...

comply to common standards

ISAcreator Configurator provides configurations to ISAcreator...

These configurations tell ISAcreator what is the minimum amount of information needed to describe experiments.

ISAcreator is packaged with a default set of configurations, however you can create your own...

MIAPEXML

MIAMEXML

MIMSXML

MIENSXML

MIGSXML

From MIENS checklist...http://precedings.nature.com/documents/5252/version/2

ISA configurator tool

....to MIENS compliant ISA configuration

Using the Configuration in ISA creator

Using the Configuration in ISA creator

enforcing next gen sequencing requirements

MISFISHIE configuration• Emage project at MRC,in Edimborough

creating an ISA- MISFIHIE configuration

Using ISA-MISFIHIE configuration

Using ISA-MISFIHIE configuration

Conclusions and future work

• From requirements to data collection

• Coherent framework helping implementing annotation guidelines

• Outreach to existing efforts to help and assist designing configurations (Chip-Seq, RNA structure mapping....)

• Further integration with MIBBI checkout

• Creation of a repository for those resources

MIBBI project / ISA configurations

AcknowledgementsDawn Field, NEBC,Eamonn Maguire, Un. of OxfordSusanna Sansone, Un. of OxfordAnnapaola Santarsiero, Un. of OxfordPeter Sterk, NEBC, WTSCChris Taylor, NEBC, MIBBI

All MIBBI collaborators