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Melanoma with Tumoral Melanosis - dermpathmd.comdermpathmd.com/cases/slide atlas/Melanoma with Tumoral Melanosis.pptx.pdf · MalignantMelanomawith%Tumoral% Melanoma...

Aug 10, 2019

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Page 1: Melanoma with Tumoral Melanosis - dermpathmd.comdermpathmd.com/cases/slide atlas/Melanoma with Tumoral Melanosis.pptx.pdf · MalignantMelanomawith%Tumoral% Melanoma Tumormelanosisisaformofregressionwith&
Page 2: Melanoma with Tumoral Melanosis - dermpathmd.comdermpathmd.com/cases/slide atlas/Melanoma with Tumoral Melanosis.pptx.pdf · MalignantMelanomawith%Tumoral% Melanoma Tumormelanosisisaformofregressionwith&
Page 3: Melanoma with Tumoral Melanosis - dermpathmd.comdermpathmd.com/cases/slide atlas/Melanoma with Tumoral Melanosis.pptx.pdf · MalignantMelanomawith%Tumoral% Melanoma Tumormelanosisisaformofregressionwith&
Page 4: Melanoma with Tumoral Melanosis - dermpathmd.comdermpathmd.com/cases/slide atlas/Melanoma with Tumoral Melanosis.pptx.pdf · MalignantMelanomawith%Tumoral% Melanoma Tumormelanosisisaformofregressionwith&
Page 5: Melanoma with Tumoral Melanosis - dermpathmd.comdermpathmd.com/cases/slide atlas/Melanoma with Tumoral Melanosis.pptx.pdf · MalignantMelanomawith%Tumoral% Melanoma Tumormelanosisisaformofregressionwith&
Page 6: Melanoma with Tumoral Melanosis - dermpathmd.comdermpathmd.com/cases/slide atlas/Melanoma with Tumoral Melanosis.pptx.pdf · MalignantMelanomawith%Tumoral% Melanoma Tumormelanosisisaformofregressionwith&
Page 7: Melanoma with Tumoral Melanosis - dermpathmd.comdermpathmd.com/cases/slide atlas/Melanoma with Tumoral Melanosis.pptx.pdf · MalignantMelanomawith%Tumoral% Melanoma Tumormelanosisisaformofregressionwith&
Page 8: Melanoma with Tumoral Melanosis - dermpathmd.comdermpathmd.com/cases/slide atlas/Melanoma with Tumoral Melanosis.pptx.pdf · MalignantMelanomawith%Tumoral% Melanoma Tumormelanosisisaformofregressionwith&
Page 9: Melanoma with Tumoral Melanosis - dermpathmd.comdermpathmd.com/cases/slide atlas/Melanoma with Tumoral Melanosis.pptx.pdf · MalignantMelanomawith%Tumoral% Melanoma Tumormelanosisisaformofregressionwith&

What  is  the  significance  of  the  collec0on  of  melanophages  adjacent  to  the  invasive  malignant  melanoma?  

Page 10: Melanoma with Tumoral Melanosis - dermpathmd.comdermpathmd.com/cases/slide atlas/Melanoma with Tumoral Melanosis.pptx.pdf · MalignantMelanomawith%Tumoral% Melanoma Tumormelanosisisaformofregressionwith&

Malignant  Melanoma  with  Tumoral  Melanoma   Tumor  melanosis  is  a  form  of  regression  with  melanomas  

  It  is  characterized  by  a  nodular  collection  of  heavily  pigmented  melanophages  

 May  need  to  bleach  the  sections  and  apply  immunohistochemical  studies  to  confirm  the  cells  are  macrophages  and  not  invasive  melanoma  cells  

Page 11: Melanoma with Tumoral Melanosis - dermpathmd.comdermpathmd.com/cases/slide atlas/Melanoma with Tumoral Melanosis.pptx.pdf · MalignantMelanomawith%Tumoral% Melanoma Tumormelanosisisaformofregressionwith&

Broad  collection  of  melanophages  

No  melanoma  cells