Medical Physics - May 2011

6000 Broken Sound Parkway, NW, Suite 300

Boca Raton, FL 33487, USA

2 For more information and a complete contents, visit www.crcpress.com

Table of Contents

Physics for Diagnostic Radiology, Third Edition ................3

Essentials of Functional MRI ............................................3

Data Mining in Biomedical Imaging, Signaling, and Systems ....................................................................4

Radiopharmaceuticals: Introduction to Drug Evaluation and Dose Estimation ..............................4

Handbook of Physics in Medicine and Biology ................5

Diffuse Optical Tomography: Principles and Applications ..............................................5

Essentials of Forensic Imaging: A Text-Atlas ......................6

Introduction to Physics in Modern Medicine, Second Edition ................................................................6

Measurement and Detection of Radiation, Third Edition ....................................................................7

Handbook of Biomedical Optics ......................................7

Quality and Safety in Radiotherapy ..................................8

Adaptive Radiation Therapy ............................................8

Quantitative MRI in Cancer ..............................................9

Informatics in Medical Imaging........................................9

Image-Guided Radiation Therapy ....................................9

Nuclear Medicine Physics ..............................................10

PACS and Digital Medicine: Essential Principles and Modern Practice ........................10

Applied Medical Image Processing: A Basic Course ........10

Handbook of Photonics for Biomedical Science..............10

Experiments in Nuclear Science......................................11

Signal Processing in Magnetic Resonance Spectroscopy with Biomedical Applications....................11

Biodental Engineering ....................................................11

Automated Image Detection of Retinal Pathology..........11

Quantitative Understanding of Biological Systems: An Introduction to Biophysics ........................................12

Handbook of Anatomical Models for Radiation Dosimetry ......................................................12

The Virtopsy Approach: 3D Optical and RadiologicalScanning and Reconstruction in Forensic Medicine ........12

In Vivo Optical Imaging of Brain Function, Second Edition ..............................................................12

Computational Intelligence in Medical Imaging: Techniques and Applications ..........................................13

Brogdon's Forensic Radiology, Second Edition................13

Advanced Signal Processing: Theory and Implementation for Sonar, Radar, and Non-Invasive Medical Diagnostic Systems, Second Edition..................14

Photoacoustic Imaging and Spectroscopy ......................14

Handbook of Radiotherapy Physics: Theory and Practice ......................................................15

PHYSICSnetBASE ............................................................15

Handbook of Nanophysics: 7-Volume Set ......................16

MBCMP11 MC

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3

Coming soon!

Physics for DiagnosticRadiologyThird EditionPhilip Palin DendyAddenbrookes NHS Trust, Cambridge, UK

Brian HeatonAberdeen Radiation Protection Services, UK

“This is the third edition of a well-established and popular textbookon physics of diagnostic radiology. It is written in a clear and con-cise style, supported by excellent illustrations. The textbookdescribes recent state-of-the-art advances in medical imaging in away radiologists, radiographers and medical physicists will findeasy to understand. It is internationally recognised as one of the keytextbooks in its field.”

—Keith Faulkner, North East Strategic Health Authority, UK

A complete course for radiologists studying for the FRCR part oneexam and for graduate students in diagnostic radiology, the thirdedition of this popular text focuses on modern developments andnew applications, including new imaging systems. The text followsthe guidelines issued by the European Association of Radiology fortraining. Its analytical approach deals in a logical order with thewide range of available imaging techniques and explains how touse imaging equipment. The book also includes the backgroundphysics necessary to understand the production of digitized images,nuclear medicine, and magnetic resonance imaging.

Contents

Fundamentals of Radiation Physics and Radioactivity. Productionof X-Rays. Interactions of X-Rays with Matter. RadiationMeasurement. The Image Receptor. The Radiological Image.Assessment of Image Quality and Optimization. ComputedTomography with X-Rays. Special Radiographic Techniques.Diagnostic Imaging with Radioactive Materials. TomographicImaging with Radionuclide. Radiobiology and Generic RadiationRisks. Radiation Doses and Risks to Patients. Practical RadiationProtection and Legislation. Diagnostic Ultrasound. MagneticResonance Imaging. Data Handling in Radiology.

Catalog no. 83155, June 2011, c. 728 pp.ISBN: 978-1-4200-8315-6, $79.95 / £49.99

Coming soon!

Essentials of Functional MRIPatrick W. StromanQueen’s University, Kingston, Ontario, Canada

“I find the book packed with information. It will be useful for botha clinical audience and MR technologists.”—W. Einar Mencl, Director of Neuroimaging Research, Haskins Laboratories

and Yale University

“A comprehensive book, combining a strong theoretical back-ground with profound practical hints for the use of fMRI in medicalresearch … represents a major step forward.”

—Massimo Filippi, Department of Neurology, Scientific Institute HSR, Italy

Functional magnetic resonance imaging (fMRI) is widely recognizedas one of the most powerful tools available for basic and clinicalresearch. With a minimum of technical jargon and advanced math-ematics, this book presents a solid, practical foundation for readersto become conversant with fMRI as a tool for their own researchand practice. The author reviews research and clinical applicationsfor disease diagnosis, treatment monitoring, and surgical planning.He also covers the underlying biophysical mechanisms that relateMRI changes to neuronal activity as well as the expanded use offMRI beyond the brain to the brainstem and spinal cord.

Contents

Introduction. Basic Concepts. Source of the MR Signal and ItsProperties. The Fundamental Building Blocks of MR ImagingMethods: Spin-Echoes and Gradient-Echoes. Creating an Imagefrom the MR Signal. Principles and Practice of fMRI. fMRI StudyDesign. fMRI Data Analysis. Clinical Applications of fMRI.Supplementary MRI Methods. Glossary. Appendices.

Catalog no. K10992, June 2011, c. 304 pp., Soft CoverISBN: 978-1-4398-1878-7, $79.95 / £49.99

For more information and a complete contents, visit www.crcpress.com

New Books in Medical Physics

http://www.crcpress.com/product/isbn/9781420083156


New!

Data Mining inBiomedical Imaging,Signaling, and SystemsEdited by

Sumeet DuaLouisiana Tech University, Ruston, USA

Rajendra Acharya UNgee Ann Polytechnic, Singapore

Approaching the techniques and challenges of image mining froma multidisciplinary perspective, this book presents data mining tech-niques, methodologies, algorithms, and strategies to analyze bio-medical signals and images. Experts in the field address data min-ing paradigms for the development of biomedical systems. Theyalso emphasize both the diagnostic and therapeutic applications ofeye imaging.

Features

• Presents system engineering principles for the design of biomedical systems

• Examines the analysis of images, sound, signal, and textualdata

• Explains typicality measures and the creation of predictivemodels in biomedicine

• Provides an in-depth treatment of image segmentation foranalysis

• Includes special coverage of knowledge discovery in mammograms

Contents

Data Mining of Acoustical Properties of Speech as Indicators ofDepression. Artificial Neural Network-Based ECG ArrhythmiaClassification. Human Reflexive Response and Its ObjectiveFunction Regarding Balance Recovery from Perturbation duringWalking. Automatic Identification of Epileptic EEG Signals UsingNonlinear Parameters. Data Mining Approach to Classify thePathological Images in Databases Using Color Image Analysis.Discovery of Association among Diseases in the Upper GastroIntestinal Tract Using Data Mining Techniques. Data AnalysisTechniques Applied to Metabolomics: Analysis and Classificationof Migraine Patterns. System Engineering Principles in the Designof Biomedical Systems. Feature Classification Methods forKnowledge Discovery in Mammograms. Mining of ImagingBiomarkers for Quantitative Evaluation of Osteoarthritis. TypicalityMeasure and the Creation of Predictive Models in Biomedicine.Automatic Segmentation Methods and Applications to BiofilmImage Analysis. On Clustering Gene Expression Time-SeriesSignals. Multi-Scale Method for Biomedical Image Segmentation.

Catalog no. K11798, May 2011, c. 448 pp.ISBN: 978-1-4398-3938-6, $109.95 / £66.99

New!

RadiopharmaceuticalsIntroduction to DrugEvaluation and DoseEstimationLawerence E. WilliamsCity of Hope National Medical Center, Duarte, California,USA

“The book covers a very important topic and fills a gap not coveredby others. I believe that it will be a very valuable in our educationof Ph.D. students and also very valuable for researchers in this area.I will recommend the book to my colleagues.”

—Sven-Erik Strand, University of Lund, Sweden

Radiopharmaceuticals starts by exploring the recent history andcurrent state of the field. Citing key research and practical exam-ples, the author then looks at how to run studies and employ esti-mation and evaluation methods that lead to the best multipleagents with the least amount of trial and error. He discusses meth-ods that allow researchers to more rigorously differentiate oneradiopharmaceutical from another, estimate radiation doses, andcorrelate results across various species to realize more informed datafrom clinical trials.

Incorporating developments in nanotechnology and radiology,with the ultimate goal of achieving personalized patient-specifictreatment, the book crosses disciplines to addresses a range of top-ics, including:

• Preclinical radiopharmaceutical development

• Organization of clinical trials

• Determination of activity in vivo

• Modeling and temporal integration with a look at the masslaw for tumor uptake as a function of tumor size (discoveredby the author)

• Absorbed dose estimates with and without clinical correlations

• Multiple-modality therapy

Written by a medical physicist who has worked directly with cancerpatients for over three decades, this book brings unique insight intothe discussion of radiopharmaceutical dosage rates and efficacy.

Catalog no. K10532, January 2011, 326 pp.ISBN: 978-1-4398-1067-5, $129.95 / £82.00





5

Handbook of Physics in Medicine and BiologyEdited by

Robert SplinterUniversity of North Carolina at Charlotte, USA

“The handbook includes hundreds of diagrams, images and tables,making it a useful tool for both medical physicists/engineers andother medical/biology specialists … includes materials that arerarely combined together, which strengthens its interdisciplinaryapproach.”

—Physics in Medicine and Biology, 55 (2010)

“My deep impression is this is an excellent work by a highly com-petent team. The book chapters follow logically from the propertiesof the cell membrane through sensors and electroreception, biome-chanics and fluid dynamics to the recording of bioelectrical signals,bioelectric impedence analysis, x-ray and computed tomography,magnetic resonance imaging, nuclear medicine, ultrasonic andthermographic imaging … keep this book close at hand and do nothesitate to use it frequently.”

—BioMedical Engineering OnLine, 2010

With contributions from experts in the lab to the clinic, this hand-book explores the full gamut of physics’ relationship to biology andmedicine in more than 40 chapters. The editor’s approach through-out is to address the major healthcare challenges, including tissueengineering and reproductive medicine, as well as the developmentof artificial organs and prosthetic devices.

The contents are organized by organ type and biological function,which is given a clear description in terms of electric, mechanical,thermodynamic, and hydrodynamic properties. In addition to thephysical descriptions, each chapter discusses principles of relatedclinical diagnostic methods and technological aspects of therapeu-tic applications. The book also focuses on regenerative engineering,emphasizing biochemical and physiochemical factors that areimportant to improving or replacing biological functions.

Catalog no. 75241, 2010, 548 pp.ISBN: 978-1-4200-7524-3, $149.95 / £95.00

New!

Diffuse OpticalTomographyPrinciples and ApplicationsHuabei JiangUniversity of Florida, Gainesville, USA

A long-awaited profile of a revolutionary imaging method, this ref-erence fuses historical perspectives and experiential anecdotes withfundamental principles and vital technical information needed tosuccessfully apply this technology—particularly in medical imaging.Involved in the field since its nascent stages, the author outlineshow to use DOT to create experimental image systems and adaptthe results of laboratory studies for use in clinical applications,including:

• Early-stage detection of breast tumors and prostate cancer

• Real-time functional brain imaging

• Joint imaging to treat progressive diseases such as arthritis

• Monitoring of tumor response

• New contrast mechanisms and multimodality methods

The book covers almost every aspect of DOT: reconstruction algo-rithms based on nonlinear iterative Newton methods, instrumenta-tion and calibration methods in both continuous-wave and fre-quency domains, and important issues of imaging contrast and spa-tial resolution. It also addresses phantom experiments, the devel-opment of various image-enhancing schemes, and reconstructionmethods based on contrast agents and fluorescence DOT.

Offering a concise description of the particular problems involved inoptical tomography, this work illustrates DOT’s fundamental foun-dations and the principle of image reconstruction. It thoroughlyexplores computational methods, forward mathematical models,and inverse strategies, clearly illustrating solutions to key equations.






New!

Essentials of ForensicImagingA Text-AtlasAngela D. LevyGeorgetown University Hospital, Washington, D.C., andUniformed Services University of the Health Sciences,Bethesda, Maryland, USA

H. Theodore HarckeArmed Forces Institute of Pathology, Washington, D.C., and Uniformed ServicesUniversity of the Health Sciences, Bethesda, Maryland, USA

“The work is very well done and makes a significant contribution tothe literature on the topic … . [It] addresses, and is applicable to,the whole range of forensic autopsies. The printing and illustrationquality is outstanding.”

—Joel Lichtenstein, University of Washington

“… The book is unusually well illustrated through correlation ofphotographs and radiological images of the highest quality. … Thebook is certain to find extended use in training programs and dailydeath investigation and documentation.”

—William A. Murphy, Jr., professor of radiology and John S. Dunn, Sr.Distinguished Chair in Diagnostic Imaging, University of Texas MD

Anderson Cancer Center

“I believe that the book will be useful for practicing forensic pathol-ogists. The numerous examples covering a wide variety of forensiccases … illustrate the value of imaging techniques in medicolegaldeath investigation.”

—John Butts, University of North Carolina at Chapel Hill

Bringing the long tradition of radiologic pathologic correlation toforensic radiology and autopsy, this volume provides readers with atechnical and interpretive foundation for applying modern cross-sectional imaging to forensic autopsy. The book integrates morethan 300 color images with basic forensic pathology in a topical for-mat. The rich pictorial display of case material that accompanies thetext establishes a contextual understanding of the material.Following an introduction to basic concepts and a review of imag-ing techniques, chapters are organized by cause of death. The atlas-like presentation is supported by full text explanations that reviewrelevant forensic and radiologic principles.

Catalog no. 91115, January 2011, 282 pp.ISBN: 978-1-4200-9111-3, $149.95 / £95.00

Introduction to Physics in Modern MedicineSecond EditionSuzanne Amador KaneHaverford College, Pennsylvania, USA

“… To make this second edition up to date, the author describes anumber of recent advances … the contents are thoroughly ground-ed in well-explained practical examples. … [a] well-researchedbook that renders complex subject matter thoroughly understand-able and enjoyable.”

—Contemporary Physics, Vol. 52, Issue 2, 2011

Fully updated, this edition builds on the bestselling original to pro-vide medical and physics students with an exploration of thephysics-related applications found in state-of-the-art medical cen-ters. Requiring very little physics, biology, or chemistry and keepingmathematics to a minimum, the applications-dedicated chaptersadhere to simple and self-contained qualitative explanations thatmake use of examples and illustrations. The book discusses the useof telescopes, lasers, ultrasound, x-rays, CT, PET, radiation therapy,and MRI in numerous application areas, including robotics, derma-tology, ophthalmology, dentistry, cardiology, cancer treatment,osteoporosis, neuroscience, and sports medicine. Supporting mate-rial is available on the author’s website.

New to the Second Edition

• Enhanced emphasis on digital imaging and computers in medicine

• Coverage of hybrid scanners for cancer imaging and the interplay of molecular medicine with imaging technologies,such as MRI, CT, and PET

• Discussion of camera pills that can film from the inside uponswallowing

• Advances in robotic surgery devices

• Recent forms of cancer treatment, including intensity-modulated radiation therapy and proton therapy

• Discussion of the use of imaging technologies in developingcountries

Catalog no. C9438, 2009, 448 pp., Soft CoverISBN: 978-1-58488-943-4, $59.95 / £38.99





7

New!

Measurement andDetection of RadiationThird EditionNicholas TsoulfanidisUniversity of Nevada, Reno, USA

Sheldon LandsbergerThe University of Texas, Austin, USA

“This book is an excellent review of nuclear detection systems. Theupdated text is particularly timely with regard to the current zeit-geist for homeland security, nuclear non-proliferation, and nuclearsecurity.”

—Steven Biegalski, University of Texas at Austin, USA

The research and applications of nuclear instrumentation havegrown substantially since publication of the previous editions. Withthe miniaturization of equipment, increased speed of electroniccomponents, and more sophisticated software, radiation detectionsystems are now more productively used in many disciplines.Continuing in the tradition of its bestselling predecessors,Measurement and Detection of Radiation, Third Edition illus-trates the fundamentals of nuclear interactions and radiation detec-tion with a multitude of examples and problems. It offers a clearlywritten, accessible introduction to nuclear instrumentation con-cepts.

New to the Third Edition

• A new chapter on the latest applications of radiation detection, covering nuclear medicine, dosimetry, healthphysics, nonproliferation, and homeland security

• Updates to all chapters and subtopics within chapters, asneeded

• Many new references and a completely updated bibliography

This third edition of a classic textbook continues to serve newcom-ers entering the nuclear science and engineering fields. It enablesthem to select the proper detector, analyze the results of countingexperiments, and perform radiation measurements that followproper health physics procedures.


Coming soon!

Handbook of BiomedicalOpticsEdited by

David A. BoasHarvard Medical School, Charlestown, Massachusetts,USA

Constantinos PitrisUniversity of Cyprus, Nicosia

Nimmi RamanujamDuke University, Durham, North Carolina, USA

Taking a broad yet detailed approach, this comprehensive, exten-sively illustrated handbook covers light-based diagnostic method-ologies and light-mediated therapeutics as well as concepts andcutting-edge optical methods used in research and practice. It pres-ents the theory, fundamentals, and state-of-the-art applications anddiscusses advantages and disadvantages of various techniques.

Contents

BACKGROUND: Geometrical Optics. Diffraction Optics. Optics:Basic Physics. Light Sources, Detectors, and Irradiation Guidelines.Tissue Optical Properties. SPECTROSCOPY AND SPECTRAL IMAG-ING: Reflectance Spectroscopy. Multi/Hyper-Spectral Imaging.Light Scattering Spectroscopy. Broadband Diffuse OpticalSpectroscopic Imaging (DOSI). Near Infrared Diffuse CorrelationSpectroscopy (DCS) for Assessment of Tissue Blood Flow.Fluorescence Spectroscopy. Raman, SERS and FTIR Spectroscopy.TOMOGRAPHIC IMAGING: Optical Coherence Tomography:Introduction and Theory. Functional Optical CoherenceTomography in Preclinical Models. Optical CoherenceTomography: Clinical Applications. Forward Models of LightTransport in Biological Tissue. Inverse Models of Light Transport.Laminar Optical Tomography. Diffuse Optical Tomography usingContinuous Wave and Frequency Domain Imaging Systems.Diffuse Optical Tomography: Time Domain. PhotoacousticTomography and Ultrasound-Modulated Optical Tomography.Optical and Photoacoustic Molecular Tomography of SmallAnimals. MICROSCOPIC IMAGING: Fourier-Domain LowCoherence Interferometry. Phase Imaging Microscopy: BeyondDarkfield, Phase and Differential Interference Contrast (DIC)Microscopy. Confocal Microscopy. Fluorescence Microscopy withStructured Excitation Illumination. Nonlinear Optical Microscopyfor Biology and Medicine. Fluorescence Lifetime ImagingMicroscopy, Endoscopy and Tomography. Application of DigitalHolographic Microscopy (DHM) in Biomedicine. Polarized LightImaging of Biological Tissues. MOLECULAR PROBE DEVELOP-MENT: Molecular Reporter Systems for Optical Imaging.Nanoparticles for Targeted Therapeutics and Diagnostics.Plasmonic Nanoprobes for Biomolecular Diagnostics of DNATargets. PHOTOTHERAPY: Photodynamic Therapy. Low LevelLaser and Light Therapy.

Catalog no. 90364, June 2011, c. 852 pp.ISBN: 978-1-4200-9036-9, $149.95 / £95.00





New!

Quality and Safety inRadiotherapyEdited by

Todd Pawlicki, Peter B. Dunscombe, Arno J. Mundt, and Pierre Scalliet

“The contents and layout are excellent.”—Eric E. Klein, Washington University School of Medicine

The first text to focus solely on quality and safety in radiotherapy,this work encompasses not only traditional technically orientedquality assurance activities, but also general approaches regardingquality and safety. The book provides an approach to quality that islong needed—one that deals with both human and technicalaspects that must be part of any overall quality improvement pro-gram. Experts both inside and outside the field discuss the process-es and people delivering the service.

The book’s seven broad categories encompass:

• Quality Management and Improvement—lean thinking, processcontrol, and access to services

• Patient Safety and Managing Error—reactive and prospectiveerror management techniques

• Methods to Assure and Improve Quality—techniques to monitor, assure, and improve quality

• People and Quality—human factors, changing roles, staffing,and training

• Quality Assurance in Radiotherapy—general issues of qualityassurance with descriptions of the key systems used to planand treat patients as well as specific recommendations on thetypes and frequencies of certain tests

• Quality Control: Equipment and Quality Control: Patient-Specific—explicit details of quality control relating toequipment and patient-specific issues


New!

Adaptive RadiationTherapyEdited by

X. Allen LiMedical College of Wisconsin, Milwaukee, USA

“Dr. Li and his colleagues are to be commended for assemblingwithin a single volume a compendium of recent vast technologicalprogress that advances us towards this paramount goal [of indi-vidualized radiation therapy].”

—From the Foreword by J. Frank Wilson

Adaptive radiation therapy (ART) offers the promise of highly indi-vidualized radiation treatment for cancer patients through cus-tomized planning and delivery. This volume describes technologicaland methodological advances in the field of ART as well as initialclinical experiences using ART for selected anatomic sites. Focusingon radiobiological basis, current technologies, and clinical applica-tions, the book covers:

• Morphological and biological biomarkers for patient-specificplanning

• Design and optimization of treatment plans

• Delivery of IMRT and IGRT intervention methodologies of ART

• Management of intrafraction variations, particularly with respiratory motion

• Quality assurance needed to ensure the safe delivery of ART

• ART applications in several common cancer types/anatomicsites

The technology and methodology for ART have advanced signifi-cantly in the last few years and accumulated clinical data havedemonstrated the need for ART in clinical settings, assisted by thewide application of IMRT and IGRT. This book shows the real poten-tial for supplying every patient with individualized radiation thera-py that is maximally accurate and precise.



The Latest Releases in the New Series

Imaging in Medical Diagnosis and Therapy

See next page for details about this new series.



New Series: Imaging in Medical Diagnosis and Therapy

9

Aims and Scope:

This series aims to present essential underlying principles from physics, biology, and medicine together with detailed,critical discussions of the state of the art and expert perspectives on future directions. It is written for students, residents,and professionals in medical physics, biomedical engineering, radiology, oncology, and allied disciplines.

If you have a book idea for the series, please contact the managing editor Luna Han [email protected]

Forthcoming Titles in the Series!

Quantitative MRI in CancerEdited by

Thomas Yankeelov, Ronald R. Price, and David R. Pickens

Catalog no. K11087, September 2011, c. 368 pp.ISBN: 978-1-4398-2057-5, $129.95 / £82.00

Informatics in Medical ImagingEdited by

George C. Kagadis and Steve G. Langer

Catalog no. K11526, September 2011, c. 504 pp.ISBN: 978-1-4398-3124-3, $149.95 / £95.00

Image-Guided Radiation TherapyEdited by

J. Daniel Bourland

Catalog no. K10143, November 2011, c. 350 pp.ISBN: 978-1-4398-0273-1, $129.95 / £82.00


Series Editor: Dr. William R. Hendee




New!

Nuclear Medicine PhysicsEdited by

Joao Jose De LimaIBILI Biophysics Institute, Coimbra, Portugal

Edited by a renowned international expert in the field, NuclearMedicine Physics offers an up-to-date, state-of-the-art account ofthe physics behind the theoretical foundation and applications ofnuclear medicine. It covers important physical aspects of the meth-ods and instruments involved in modern nuclear medicine, alongwith related biological topics. The book discusses the production ofradioisotopes and radiopharmaceuticals, positron physics andpositron applications in medicine and biology, and modern radia-tion detectors and measuring methods. It also explores systems innuclear medicine, imaging methodologies, dosimetry, and the bio-logical effects of radiation.

Catalog no. C7958, January 2011, 524 pp.ISBN: 978-1-58488-795-9, $149.95 / £95.00

New!

PACS and DigitalMedicineEssential Principles andModern PracticeYu LiuSt. Luke’s Medical Center, Milwaukee, Wisconsin, USA

Jihong WangUniversity of Texas MD Anderson Cancer Center, Houston, USA

“… a thorough and practical reference for radiologists, adminis-trators, engineers, and others who might create, manage, or usesuch a system. …”

—SciTech Book News, February 2011

This useful guide presents key principles and practical steps for PACSand EHR implementations and maintenance. It explains how PACSare used in radiology, teleradiology, cardiology, pathology, and radi-ation oncology. The authors cover PACS system components, qual-ity control, IT infrastructures, networks, and data storage technolo-gies. They also describe industry standards; security, privacy, andsafety regulations; and the replacement of legacy systems.

Catalog no. C8365, January 2011, 367 pp.ISBN: 978-1-4200-8365-1, $129.95 / £82.00

New!

Applied Medical Image ProcessingA Basic CourseWolfgang BirkfellnerMedical University of Vienna, Austria

“The plethora of examples in each chapter … allows the reader toapply the theory and visually assess the outcomes. This book is aperfect blend of theory and practice. I highly recommend it.”

—Pascal Fallavollita, Technische Universität München

Using real medical images and techniques, this book provides atruly introductory guide to medical image processing. The authorcombines clearly written explanations with numerous tables, dia-grams, and figures as well as illustrative examples and exercisesusing MATLAB® and Octave. An accompanying CD contains imagesand files to be used with either program.


Handbook of Photonics for Biomedical ScienceEdited by

Valery V. TuchinSaratov State University, Russia

Addressing the latest problems in biomedical optics and biopho-tonics, this handbook describes advanced biophotonics methodsand techniques intensively developed in recent years. It discussesoptical and terahertz spectroscopy and imaging methods for bio-medical diagnostics based on the interaction of coherent, polarized,and acoustically modulated radiation with tissues and cells. It cov-ers modalities of nonlinear spectroscopic microscopies, photonictechnologies for therapy and surgery, and nanoparticle photonictechnologies for cancer treatment and UV radiation protection. Thetext also elucidates the advanced spectroscopy and imaging of nor-mal and pathological tissues.

Catalog no. K10313, 2010, 868 pp.ISBN: 978-1-4398-0628-9, $149.95 / £95.00







11

New!

Experiments in Nuclear ScienceSidney A. KatzRutgers University, Camden, New Jersey, USA

Jeff C. BryanUniversity of Wisconsin, La Crosse, USA

Based on experiments performed by hundreds of students, thisintroductory-level laboratory manual provides hands-on opportuni-ties for developing insights into the origins and properties of nuclearradiations, their interactions with matter, their detection and meas-urement, and their applications in the physical and life sciences.Each of the 32 exercises includes an overview of the scientific phe-nomenon; instructions for conducting the experiments, recordingand analyzing the data, and reporting the results; specific questionsrelating to the experiments; and several problems relating to thescientific phenomena being investigated.

Catalog no. K11568, January 2011, 198 pp., Soft CoverISBN: 978-1-4398-3481-7, $49.95 / £31.99

Signal Processing inMagnetic ResonanceSpectroscopy withBiomedical ApplicationsDzevad Belkic and Karen BelkicKarolinska Institute, Stockholm, Sweden

Addressing the critical need in clinical oncology for robust and sta-ble signal processing in MRS, this book explores cutting-edge the-ory-based innovations for obtaining reliable quantitative informa-tion from MR signals for cancer diagnostics. By defining the naturalframework of signal processing using the well-established theory ofquantum physics, it illustrates how advances in signal processingcan optimize MRS. Applying the fast Padé transform (FPT) to sever-al problems in oncology diagnostics, including ovarian, breast, andprostate cancer, the book examines the remarkable ability of theFPT to unambiguously quantify isolated, tightly overlapped, andnearly confluent resonances.


Biodental EngineeringEdited by

R.M. Natal Jorge, Sónia M. Santos, João Manuel R.S. Tavares, Mário A.P. Vaz, and Reis Campos University of Porto, Portugal

Explaining how bioengineering is applied to dentistry, this volumecovers the state of the art in biomechanical disorders, orthodontics,implantology, aesthetics, dental systems, medical devices, andmedical images. It discusses a host of techniques and methodolo-gies, including the finite element method, experimental tech-niques, rapid prototyping, and image processing and analysis. Thebook also explores composite materials, clinical studies, biomateri-als, fracture mechanics, osseointegration, biomechanics, dentalprostheses, dental systems and equipments, and mechanical biolo-gy.


Automated ImageDetection of RetinalPathologyHerbert JelinekMedical University of Vienna, Austria

Michael J. CreeUniversity of Waikato, Hamilton, New Zealand

Offering an array of informative examples, this book analyzes theuse of automated computer techniques, such as pattern recogni-tion, in analyzing retinal images and detecting diabetic retinopathyand its progression as well as other retinal-based diseases. It alsoaddresses the benefits and challenges of automated health care inthe field of ophthalmology. The book then details the increasingpractice of telemedicine screening and other advanced applica-tions, including arteriolar-venous ratio, which has been shown to bean early indicator of cardiovascular, diabetes, and cerebrovascularrisk.








New!

QuantitativeUnderstanding ofBiosystemsAn Introduction to BiophysicsThomas M. NordlundUniversity of Alabama at Birmingham, USA

“Combines a nice balance of topics with important basic material… . The emphasis on problems, projects, and tools is very helpful.”

—Stephen J. Hagen, University of Florida, Gainesville, USA

This color text clearly describes the biological physics of macromol-ecules, subcellular structures, and whole cells, including interactionswith light. It provides a hands-on understanding of the movementof microorganisms, reviews the necessary mathematics, discussesquantum mechanics in biosystems, and describes the transitionfrom discreet random walks to continuum diffusive motion. Anaccompanying CD includes a wealth of interactive material.

Catalog no. 89772, March 2011, c. 583 pp.ISBN: 978-1-4200-8972-1, $89.95 / £57.99

Handbook of AnatomicalModels for RadiationDosimetryEdited by

Xie George XuRensselaer Polytechnic Institute, Troy, New York, USA

Keith F. EckermanOak Ridge National Laboratory, Tennessee, USA

This pioneering handbook brings together recommendations sanc-tioned by the International Commission on Radiological Protection(ICRP) and documents 40 years of cutting-edge work with MonteCarlo codes and radiation protection dosimetry. Assembling thework of nearly all major phantom (computational model) develop-ers around the world, the book provides detailed accounts of eachwell-known phantom, including those for a host of medical appli-cations as well as for radiation protection dosimetry applicationsinvolving environmental, nuclear power plant, and internal con-tamination exposures. Related data sets can be downloaded fromthe authors’ website.

Catalog no. C5979, 2010, 757 pp.ISBN: 978-1-4200-5979-3, $133.95 / £85.00

The Virtopsy Approach3D Optical and RadiologicalScanning and Reconstructionin Forensic MedicineEdited by

Michael J. Thali, Richard Dirnhofer, andPeter Vock

“This excellent text is …a stepping-stone which may motivateforensic scientists to tackle the many unsolved problems and ques-tions in forensic science using modem methods that have proventheir enormous value in chemistry and medicine.”

—Michael J. Shkrum, Canadian Society of Forensic Science, Vol. 43, No. 1, March 2010

“The very first book on virtopsy and excellent at that. I would imag-ine that every forensic pathologist and radiologist must read thisone. …”

—Anil Aggrawal’s Internet Journal of Forensic Medicine and Toxicology, Vol.10, No. 2, July-December 2009


In Vivo Optical Imaging of Brain FunctionSecond EditionEdited by

Ron FrostigUniversity of California, Irvine, USA

This new edition, as with the original, reaches across disciplines toreview a variety of noninvasive optical techniques used to studyactivity in the living brain. Leading authorities from such diverseareas as optical hardware, cognitive behavior, and neurosciencepresent a host of perspectives that range from a single neuron tolarge assemblies of neurons several million strong, captured at var-ious temporal and spatial resolutions. Introducing techniques thatwere unavailable just a few years ago, the book describes their the-ory, setup, analytical methods, and examples that highlight theadvantages of each particular method.








13

ComputationalIntelligence in MedicalImagingTechniques and ApplicationsEdited by

Gerald SchaeferAston University, Birmingham, UK

Aboul Ella HassanienKuwait University, Safat

Jianmin JiangUniversity of Bradford, West Yorkshire, UK

“In choosing this book the reader will be exposed to the range ofexciting research that is being conducted in the context of medicalimaging. … I am sure that this collection of the latest trends anddevelopments will further stimulate discussion and development ofnew solutions. The book will be of interest and relevance to anyoneinvolved in the computational analysis and interpretation ofimages—whether medical or not.”

—International Statistical Review, 2009

A compilation of trends in the field, this book explores how intelli-gent computing can bring enormous benefit to existing technolo-gy in medical image processing as well as improve medical imag-ing research. It covers research toward integrating medical imageprocessing with artificial intelligence and machine learningapproaches.

Helping you achieve accurate results when analyzing medicalimages, the book presents numerous techniques, algorithms, andmodels. The contributors discuss how these techniques are used toclassify images, analyze cancer, handle the inherent uncertainties inmammographic images, reconstruct images, and much more.

Features

• Reflects forefront research in intelligent medical image processing

• Explores a range of computational algorithms and techniques,such as neural networks, fuzzy sets, evolutionary optimization,and Monte Carlo simulations

• Encompasses many important applications, including the identification of melanoma and prostate cancer analysis

• Describes a comprehensive system for handling and using biomedical image databases

Catalog no. C6059, 2009, 504 pp.ISBN: 978-1-4200-6059-1, $102.95 / £65.99

New!

Brogdon’s ForensicRadiologySecond EditionEdited by

Michael J. ThaliUniversity of Berne, Switzerland

Mark D. VinerCranfield Forensic Institute, Wiltshire, UK

B.G. BrogdonUniversity of South Alabama, Medical Center, Mobile, USA

A milestone in the forensic community, the benchmark first editionof Forensic Radiology was a bestseller throughout the world and astandard reference for practitioners and educators alike. Like itspredecessor, Brogdon’s Forensic Radiology, Second Edition cov-ers the entire scope of radiological applications in the forensic sci-ences, profiling current and anticipated uses of new modalities andtechniques.


• New chapter on the radiologist as an expert witness

• Modern cross-sectional imaging in anthropology

• New approaches to radiology in mass casualty situations

• An entirely new section on the use of virtual imaging and virtopsy

• Forensic and clinical usage of x-rays in body packing for drug smuggling

• Imaging in the medical examiner’s facility and in the field

• Radiology of special objects, antiquities, and mummies

Enhanced with more than 1300 images, the book includes an intro-duction to forensic radiology, offering historical perspectives anddefinitions used in the field. It provides instruction on trial prepara-tion and effective courtroom testimony, demonstrates the use offorensic radiology in identification of the dead, and explores the useof radiology to help in gunshot and abuse cases and in nonviolentcrimes. The book also examines technological and safety issues.






Advanced SignalProcessingTheory and Implementationfor Sonar, Radar, and Non-Invasive Medical DiagnosticSystems, Second EditionEdited by

Stergios StergiopoulosUniversity of Western Ontario, Canada

As advances in algorithms and computer technology have bol-stered the digital signal processing capabilities of real-time sonar,radar, and non-invasive medical diagnostics systems, cutting-edgemilitary and defense research has established conceptual similaritiesin these areas. Now civilian enterprises can use government inno-vations to facilitate optimal functionality of complex real-time sys-tems. Advanced Signal Processing details a cost-efficient genericprocessing structure that exploits these commonalities to benefitcommercial applications.

Edited by a renowned defense scientist, researcher, and innovator,this volume preserves the mathematical focus and key informationfrom the first edition that provided invaluable coverage adaptivesystems, advanced beamformers, and volume visualization meth-ods in medicine. This edition integrates the best features of non-lin-ear and conventional algorithms and discusses their application inPC-based architectures. It also explains adaptive, synthetic-aperture,and fusion-processing schemes with near-instantaneous conver-gence in 2D and 3D sensors.


• Advances in biometrics, image segmentation, registration, andfusion techniques for 3D/4D ultrasound, CT, and MRI

• Fully digital 3D/4D: 3D+time ultrasound system technology,computing architecture requirements, and relevant implementation issues

• State-of-the-art non-invasive medical procedures, non-destructive 3D tomography imaging and biometrics, andmonitoring of vital signs

• Cardiac motion correction in multi-slice x-ray CT imaging

• Space-time adaptive processing and detection of targets interference-intense backgrounds comprised of clutter andjamming


Photoacoustic Imagingand SpectroscopyEdited by

Lihong V. WangWashington University, St. Louis, Missouri, USA

While photoacoustic imaging is probably the fastest growing bio-medical imaging technology, this book is the first comprehensivevolume in this emerging field that covers both the physics and theremarkable noninvasive applications that are changing diagnosticmedicine. Bringing together leading pioneers in the field, the bookpresents a full account of recent research and developing applica-tions in the area of biomedical photoacoustics.

Photoacoustics promises to revolutionize medical imaging and maywell make as dramatic a contribution to modern medicine as thediscovery of the x-ray itself once did. Photoacoustics can providefunctional sensing of physiological parameters, such as the oxygensaturation of hemoglobin. It can also provide high-contrast functional imaging of angiogenesis and hypermetabolism in tumorsin vivo. Discussing these remarkable noninvasive applications andso much more, this reference is essential reading for all researchersin medical imaging and for clinicians working at the cutting edgeof modern biotechnology to develop diagnostic techniques thatcan save many lives and just as importantly do no harm.

Features

• Provides a full review of photoacoustic, optoacoustic, and thermoacoustic imaging

• Covers fundamentals of the science behind photoacoustics,including the physics and critical algorithms

• Details imaging methods and instrumentation

• Reviews both functional and molecular imaging

• Includes numerous black and white illustrations as well as acolor insert that compares x-ray and ultrasonic images withphotoacoustic images






15

Bestseller!

Handbook ofRadiotherapy PhysicsTheory and PracticeEdited by

P. Mayles, A. Nahum, and J.C. Rosenwald

“… Due to the broad range of topics covered and the clear, conciseexplanations, this text would be ideal for anyone wishing to studyor refresh their knowledge of any central area of radiotherapyphysics. … In comparison to other reference texts, the Handbookof Radiotherapy Physics is clear and also filled with many knowl-edgeable and useful observations and notes. … It is an excellent ref-erence text and sits nicely on the shelf alongside your old copy ofWilliams and Thwaites.”

—SCOPE, December 2009

“… comprehensive reference … With contributions from renownedspecialists, this book provides essential theoretical and practicalknowledge to deliver safe and effective radiotherapy.”

—Anticancer Research, 2009, Vol. 29

“The editors have managed with great success to assemble theinformation submitted by the contributing authors and put it in aformat that is concise, easy to read, and rich in content … it canserve as an excellent reference manual and resource.”

—Niko Papanikolaou, University of Texas Health Sciences Center, Medical Physics, September 2008, Vol. 35, No. 9

From background physics and biological models to imaging andtreatment modalities, this handbook covers all theoretical and prac-tical aspects of radiotherapy physics and biology. The first threeparts present the fundamentals of the underlying physics, radiobi-ology, and technology involved. The ensuing sections discuss thesupport requirements of external beam radiotherapy, followed by apart that explores advances in photon and particle therapy.Subsequent sections examine brachytherapy using sealed andunsealed sources and provide the framework of radiation protec-tion, including an appendix that describes the detailed applicationof UK legislation. The final part contains useful tables of both phys-ical constants and attenuation data.

Catalog no. IP345, 2007, 1450 pp.ISBN: 978-0-7503-0860-1, $299.95 / £191.00



• Applied & Industrial Physics

• Applied Mechanics & FluidDynamics

• Astronomy & Astrophysics

• Atomic & Molecular Physics

• Biophysics

• Chemical Physics

• Computational Physics

• Condensed Matter &Materials Science

• General & IntroductoryPhysics

• Geophysics

• Lasers, Optics &Optoelectronics

• Mathematical Physics

• Medical Physics

• Nonlinear Physics

• Nuclear Physics

• Particle/High Energy Physics

• Plasma Physics

• Quantum Physics

• Statistical Physics andThermodynamics

From astrophysics to quantum physics, materials science to opto-electronics, this unified e-library offers fundamental theories andcontemporary investigations of time, matter, and space. It includesmany volumes from the world-renowned Institute of Physics.

Discounts do not apply to netBASEs

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— Volumes are also available separately —

Explore the frontiers of nanoscienceBreakthroughs in nanotechnology require a firmgrounding in the principles of nanophysics.Providing the framework to achieve theseadvances, Handbook of Nanophysics is the firstcomprehensive reference to cover both fundamen-tal and applied aspects of physics at the nanoscale.Pioneering scientists from preeminent academicinstitutions, R&D companies, and research labora-tories pave the way for new innovations in nan-otechnology.

• Introductions in each chapter—useful to nonspecialists and students

• Chapters extensively peer reviewed by senior scientists innanophysics and related areas ofnanoscience

• A didactic treatment of the physics underlying the nanoscalematerials and applications alongwith detailed experimental results

• State-of-the-art scientific content enriched with fundamental equations and illustrations, some in color

Each volume includes:

Catalog no. 75381, January 20115670 pp., ISBN: 978-1-4200-7538-0$950.00 / £600.00

Edited by

Klaus D. Sattler, University of Hawaii-Manoa, Honolulu, USA


Medical Physics - May 2011

Documents

biomedical imaging

handbook of physics

forensic medicine

nuclear medicine physics

essentials of forensic

modern medicine

biomedical applications

photoacoustic imaging