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Medical Imaging – Introduction Jan Kybic February 16, 2010
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Medical Imaging -- Introduction - CMPcmp.felk.cvut.cz/cmp/courses/ZSL2/slidy/medicalImagingIntro.pdf · Understanding Imaging Medium ... Medical imaging pipeline patient/subject Physical

May 01, 2018

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Page 1: Medical Imaging -- Introduction - CMPcmp.felk.cvut.cz/cmp/courses/ZSL2/slidy/medicalImagingIntro.pdf · Understanding Imaging Medium ... Medical imaging pipeline patient/subject Physical

Medical Imaging – Introduction

Jan Kybic

February 16, 2010

Page 2: Medical Imaging -- Introduction - CMPcmp.felk.cvut.cz/cmp/courses/ZSL2/slidy/medicalImagingIntro.pdf · Understanding Imaging Medium ... Medical imaging pipeline patient/subject Physical

Medical imaging: a collaborative paradigm

picture from Atam P. Dhawan: Medical Imaging

Page 3: Medical Imaging -- Introduction - CMPcmp.felk.cvut.cz/cmp/courses/ZSL2/slidy/medicalImagingIntro.pdf · Understanding Imaging Medium ... Medical imaging pipeline patient/subject Physical

From physiology to information processing

(what we should learn)

◮ Understanding Imaging Medium

◮ Physics of Imaging

◮ Imaging Instrumentation

◮ Data Acquisition Methods

◮ Image Processing and Analysis

Page 4: Medical Imaging -- Introduction - CMPcmp.felk.cvut.cz/cmp/courses/ZSL2/slidy/medicalImagingIntro.pdf · Understanding Imaging Medium ... Medical imaging pipeline patient/subject Physical

From physiology to information processing

(what we should learn)

◮ Understanding Imaging Medium

◮ Physics of Imaging

◮ Imaging Instrumentation

◮ Data Acquisition Methods

◮ Image Processing and Analysis

Page 5: Medical Imaging -- Introduction - CMPcmp.felk.cvut.cz/cmp/courses/ZSL2/slidy/medicalImagingIntro.pdf · Understanding Imaging Medium ... Medical imaging pipeline patient/subject Physical

From physiology to information processing

(what we should learn)

◮ Understanding Imaging Medium

◮ Physics of Imaging

◮ Imaging Instrumentation

◮ Data Acquisition Methods

◮ Image Processing and Analysis

Page 6: Medical Imaging -- Introduction - CMPcmp.felk.cvut.cz/cmp/courses/ZSL2/slidy/medicalImagingIntro.pdf · Understanding Imaging Medium ... Medical imaging pipeline patient/subject Physical

From physiology to information processing

(what we should learn)

◮ Understanding Imaging Medium

◮ Physics of Imaging

◮ Imaging Instrumentation

◮ Data Acquisition Methods

◮ Image Processing and Analysis

Page 7: Medical Imaging -- Introduction - CMPcmp.felk.cvut.cz/cmp/courses/ZSL2/slidy/medicalImagingIntro.pdf · Understanding Imaging Medium ... Medical imaging pipeline patient/subject Physical

From physiology to information processing

(what we should learn)

◮ Understanding Imaging Medium

◮ Physics of Imaging

◮ Imaging Instrumentation

◮ Data Acquisition Methods

◮ Image Processing and Analysis

Page 8: Medical Imaging -- Introduction - CMPcmp.felk.cvut.cz/cmp/courses/ZSL2/slidy/medicalImagingIntro.pdf · Understanding Imaging Medium ... Medical imaging pipeline patient/subject Physical

Medical imaging pipeline

Page 9: Medical Imaging -- Introduction - CMPcmp.felk.cvut.cz/cmp/courses/ZSL2/slidy/medicalImagingIntro.pdf · Understanding Imaging Medium ... Medical imaging pipeline patient/subject Physical

Medical imaging pipeline

patient/subject

Physical property

Imaging device

Raw data

Preprocessing

Improved data

ReconstructionImages/volumes

Interpretation

Quantitative/qualitative inf.

physician Decision

Page 10: Medical Imaging -- Introduction - CMPcmp.felk.cvut.cz/cmp/courses/ZSL2/slidy/medicalImagingIntro.pdf · Understanding Imaging Medium ... Medical imaging pipeline patient/subject Physical

Medical imaging pipeline

patient/subject

Physical property

Imaging device

Raw data

Preprocessing

Improved data

ReconstructionImages/volumes

Interpretation

Quantitative/qualitative inf.

physician Decision

Page 11: Medical Imaging -- Introduction - CMPcmp.felk.cvut.cz/cmp/courses/ZSL2/slidy/medicalImagingIntro.pdf · Understanding Imaging Medium ... Medical imaging pipeline patient/subject Physical

Medical imaging pipeline

patient/subject

Physical property

Imaging device

Raw data

Preprocessing

Improved data

ReconstructionImages/volumes

Interpretation

Quantitative/qualitative inf.

Statistical processingphysician Decision

Page 12: Medical Imaging -- Introduction - CMPcmp.felk.cvut.cz/cmp/courses/ZSL2/slidy/medicalImagingIntro.pdf · Understanding Imaging Medium ... Medical imaging pipeline patient/subject Physical

Imaging device

Imaging device

Physical property:density, absorbance,

conductivity, . . . Raw data

Examples:

◮ CT, X-rays, MRI, ultrasound, . . .

Page 13: Medical Imaging -- Introduction - CMPcmp.felk.cvut.cz/cmp/courses/ZSL2/slidy/medicalImagingIntro.pdf · Understanding Imaging Medium ... Medical imaging pipeline patient/subject Physical

Preprocessing

A priori

knowledge

PreprocessingRaw data

Preprocessed, cleaned,enhanced data

Examples:

◮ Noise suppression, contract enhancement, intensity equalization,outlier elimination, bias compensation, time/space filtering, . . .

Page 14: Medical Imaging -- Introduction - CMPcmp.felk.cvut.cz/cmp/courses/ZSL2/slidy/medicalImagingIntro.pdf · Understanding Imaging Medium ... Medical imaging pipeline patient/subject Physical

Reconstruction

Physics of the acquisition

device

ReconstructionPreprocessed raw data

Physically meaningfullimages, volumes, sequences

◮ Inverse problem

Examples:◮ Tomographic reconstruction

◮ MRI, ultrasound . . .

Page 15: Medical Imaging -- Introduction - CMPcmp.felk.cvut.cz/cmp/courses/ZSL2/slidy/medicalImagingIntro.pdf · Understanding Imaging Medium ... Medical imaging pipeline patient/subject Physical

Interpretation

A priori

knowledge

InterpretationHigh-level

processing

Images, volumes,sequences

Quantitative& qualitative inf.

size, changes,metabolic inf.

Examples:

◮ Registration, segmentation, classification, tracking,. . .

Page 16: Medical Imaging -- Introduction - CMPcmp.felk.cvut.cz/cmp/courses/ZSL2/slidy/medicalImagingIntro.pdf · Understanding Imaging Medium ... Medical imaging pipeline patient/subject Physical

Modalities

Page 17: Medical Imaging -- Introduction - CMPcmp.felk.cvut.cz/cmp/courses/ZSL2/slidy/medicalImagingIntro.pdf · Understanding Imaging Medium ... Medical imaging pipeline patient/subject Physical

Classification of medical modalities

◮ What information do we need?◮ anatomical, physiological, functional

Page 18: Medical Imaging -- Introduction - CMPcmp.felk.cvut.cz/cmp/courses/ZSL2/slidy/medicalImagingIntro.pdf · Understanding Imaging Medium ... Medical imaging pipeline patient/subject Physical

Classification of medical modalities

◮ What information do we need?◮ anatomical, physiological, functional

◮ What is the energy source?◮ external, internal, combined

Page 19: Medical Imaging -- Introduction - CMPcmp.felk.cvut.cz/cmp/courses/ZSL2/slidy/medicalImagingIntro.pdf · Understanding Imaging Medium ... Medical imaging pipeline patient/subject Physical

Classification of medical modalities

◮ What information do we need?◮ anatomical, physiological, functional

◮ What is the energy source?◮ external, internal, combined

◮ How good is the image?◮ resolution, noise

Page 20: Medical Imaging -- Introduction - CMPcmp.felk.cvut.cz/cmp/courses/ZSL2/slidy/medicalImagingIntro.pdf · Understanding Imaging Medium ... Medical imaging pipeline patient/subject Physical

Classification of medical modalities

◮ What information do we need?◮ anatomical, physiological, functional

◮ What is the energy source?◮ external, internal, combined

◮ How good is the image?◮ resolution, noise

◮ How much does it cost?

Page 21: Medical Imaging -- Introduction - CMPcmp.felk.cvut.cz/cmp/courses/ZSL2/slidy/medicalImagingIntro.pdf · Understanding Imaging Medium ... Medical imaging pipeline patient/subject Physical

Energy source

Page 22: Medical Imaging -- Introduction - CMPcmp.felk.cvut.cz/cmp/courses/ZSL2/slidy/medicalImagingIntro.pdf · Understanding Imaging Medium ... Medical imaging pipeline patient/subject Physical

Electromagnetic spectrum

Page 23: Medical Imaging -- Introduction - CMPcmp.felk.cvut.cz/cmp/courses/ZSL2/slidy/medicalImagingIntro.pdf · Understanding Imaging Medium ... Medical imaging pipeline patient/subject Physical

Examples

Page 24: Medical Imaging -- Introduction - CMPcmp.felk.cvut.cz/cmp/courses/ZSL2/slidy/medicalImagingIntro.pdf · Understanding Imaging Medium ... Medical imaging pipeline patient/subject Physical

Microscopy

Optical microscopy – since 17th century; Jensen, van Leeuwenhoek,Galilei, . . .

Page 25: Medical Imaging -- Introduction - CMPcmp.felk.cvut.cz/cmp/courses/ZSL2/slidy/medicalImagingIntro.pdf · Understanding Imaging Medium ... Medical imaging pipeline patient/subject Physical

X-rays / Radiography

1895, W. Rontgen B. Rontgen hand modern hand

Page 26: Medical Imaging -- Introduction - CMPcmp.felk.cvut.cz/cmp/courses/ZSL2/slidy/medicalImagingIntro.pdf · Understanding Imaging Medium ... Medical imaging pipeline patient/subject Physical

Computed tomography

The machine:

Page 27: Medical Imaging -- Introduction - CMPcmp.felk.cvut.cz/cmp/courses/ZSL2/slidy/medicalImagingIntro.pdf · Understanding Imaging Medium ... Medical imaging pipeline patient/subject Physical

Ultrasound – Equipment

Page 28: Medical Imaging -- Introduction - CMPcmp.felk.cvut.cz/cmp/courses/ZSL2/slidy/medicalImagingIntro.pdf · Understanding Imaging Medium ... Medical imaging pipeline patient/subject Physical

MEG and EEG

Magnetoencephalography Electroencephalography

Page 29: Medical Imaging -- Introduction - CMPcmp.felk.cvut.cz/cmp/courses/ZSL2/slidy/medicalImagingIntro.pdf · Understanding Imaging Medium ... Medical imaging pipeline patient/subject Physical

Magnetic resonance imaging (MRI)

Larmor, Bloch, Purcell, Rabi, Lauterbur,. . . around 1973.

Page 30: Medical Imaging -- Introduction - CMPcmp.felk.cvut.cz/cmp/courses/ZSL2/slidy/medicalImagingIntro.pdf · Understanding Imaging Medium ... Medical imaging pipeline patient/subject Physical

. . . and many others

◮ SPECT (Single Photon Emission Computed Tomography)

◮ PET (Positron Emission Tomography)

◮ gamma camera

◮ termography

◮ . . .

Page 31: Medical Imaging -- Introduction - CMPcmp.felk.cvut.cz/cmp/courses/ZSL2/slidy/medicalImagingIntro.pdf · Understanding Imaging Medium ... Medical imaging pipeline patient/subject Physical

OK, here ends the preview. Questions?

. . . otherwise let us start with image processing