09/04/2003 MEDC 501 Fall 2003 1 MEDC 501 Introductory Medicinal Chemistry √ Bond, chemical bonding, ionic bond, hybridization, hybrid orbitals, hybdrization in methane, ethylene, acetylene, benzene, and aromatics √ Bond polarity, electronegativity, Kier-Hall eN scale, dependence of physical and chemical properties, and structure on bond polarity √ Consequences of bond polarity, inductive effect, pkA values, resonance effect, cumulative effects, molecular action of drugs Topics to be covered
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09/04/2003 MEDC 501 Fall 2003 1
MEDC 501 Introductory Medicinal Chemistry
√ Bond, chemical bonding, ionic bond, hybridization, hybrid
orbitals, hybdrization in methane, ethylene, acetylene,
benzene, and aromatics
√ Bond polarity, electronegativity, Kier-Hall eN scale,
dependence of physical and chemical properties, and
structure on bond polarity
√ Consequences of bond polarity, inductive effect, pkA