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MCC BP Based on work by K. Foglia www.kimunity.com Chapter 5. Macromolecules
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MCC BP Based on work by K. Foglia Chapter 5. Macromolecules.

Dec 28, 2015

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Page 1: MCC BP Based on work by K. Foglia  Chapter 5. Macromolecules.

MCC BPBased on work by K. Foglia

www.kimunity.com

Chapter 5.

Macromolecules

Page 2: MCC BP Based on work by K. Foglia  Chapter 5. Macromolecules.

MCC BPBased on work by K. Foglia

www.kimunity.com

Macromolecules Smaller organic molecules join together

to form larger molecules macromolecules

4 major classes of macromolecules: carbohydrates lipids proteins nucleic acids

Page 3: MCC BP Based on work by K. Foglia  Chapter 5. Macromolecules.

MCC BPBased on work by K. Foglia

www.kimunity.com

Polymers Long molecules built by linking chain

of repeating smaller units polymers monomers = repeated small units covalent bonds

Page 4: MCC BP Based on work by K. Foglia  Chapter 5. Macromolecules.

MCC BPBased on work by K. Foglia

www.kimunity.com

How to build a polymer Condensation reaction

dehydration synthesis joins monomers by “taking” H2O out

1 monomer provides OH the other monomer provides H together these

form H2O

requires energy & enzymes

Page 5: MCC BP Based on work by K. Foglia  Chapter 5. Macromolecules.

MCC BPBased on work by K. Foglia

www.kimunity.com

How to break down a polymer

Hydrolysis use H2O to break apart monomers

reverse of condensation reaction

H2O is split into H and OH

H & OH group attach where the covalent bond used to be

ex: digestion is hydrolysis

Page 6: MCC BP Based on work by K. Foglia  Chapter 5. Macromolecules.

MCC BPBased on work by K. Foglia

www.kimunity.com

Carbohydrates

Page 7: MCC BP Based on work by K. Foglia  Chapter 5. Macromolecules.

MCC BPBased on work by K. Foglia

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So what’s all this talk about carbs?

Atkin’s Diet

South Beach Diet

Page 8: MCC BP Based on work by K. Foglia  Chapter 5. Macromolecules.

MCC BPBased on work by K. Foglia

www.kimunity.com

Carbohydrates Carbohydrates are composed of C, H, O

carbo - hydr - ate

CH2O

(CH2O)x C6H12O6

Function: energy energy storage raw materials structural materials

Monomer: sugars

ex: sugars & starches

Page 9: MCC BP Based on work by K. Foglia  Chapter 5. Macromolecules.

MCC BPBased on work by K. Foglia

www.kimunity.com

Sugars Most names for sugars end in -ose Classified by number of carbons

6C = hexose (glucose) 5C = pentose (fructose, ribose) 3C = triose (glyceraldehyde)

Page 10: MCC BP Based on work by K. Foglia  Chapter 5. Macromolecules.

MCC BPBased on work by K. Foglia

www.kimunity.com

What functional groups?

carbonyl

ketone

aldehyde

hydroxyl

Page 11: MCC BP Based on work by K. Foglia  Chapter 5. Macromolecules.

MCC BPBased on work by K. Foglia

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Sugar structure 5C & 6C sugars form rings in aqueous solutions

in cells!

Carbons are numbered

Page 12: MCC BP Based on work by K. Foglia  Chapter 5. Macromolecules.

MCC BPBased on work by K. Foglia

www.kimunity.com

Numbered carbons

C

CC

C

CC

1'

2'3'

4'

5'

6'

O

Page 13: MCC BP Based on work by K. Foglia  Chapter 5. Macromolecules.

MCC BPBased on work by K. Foglia

www.kimunity.com

Simple & complex sugars Monosaccharides

simple 1 monomer sugars glucose

Disaccharides 2 monomers sucrose

Polysaccharides large polymers starch

Page 14: MCC BP Based on work by K. Foglia  Chapter 5. Macromolecules.

MCC BPBased on work by K. Foglia

www.kimunity.com

Building sugars Dehydration synthesis

|glucose

|glucose

glycosidic linkage

monosaccharides disaccharide

|maltose

Page 15: MCC BP Based on work by K. Foglia  Chapter 5. Macromolecules.

MCC BPBased on work by K. Foglia

www.kimunity.com

Building sugars Dehydration synthesis

|fructose

|glucose

glycosidic linkage

monosaccharides disaccharide

|sucrose

structural isomers

Page 16: MCC BP Based on work by K. Foglia  Chapter 5. Macromolecules.

MCC BPBased on work by K. Foglia

www.kimunity.com

Polysaccharides Polymers of sugars

costs little energy to build easily reversible = release energy

Function: energy storage

starch (plants) glycogen (animals)

building materials = structure cellulose (plants) chitin (arthropods & fungi)

Page 17: MCC BP Based on work by K. Foglia  Chapter 5. Macromolecules.

MCC BPBased on work by K. Foglia

www.kimunity.com

Branched vs linear polysaccharides

Page 18: MCC BP Based on work by K. Foglia  Chapter 5. Macromolecules.

MCC BPBased on work by K. Foglia

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Polysaccharide diversity Molecular structure determines function

isomers of glucose How does structure influence function…

Page 19: MCC BP Based on work by K. Foglia  Chapter 5. Macromolecules.

MCC BPBased on work by K. Foglia

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Digesting starch vs. cellulose

Page 20: MCC BP Based on work by K. Foglia  Chapter 5. Macromolecules.

MCC BPBased on work by K. Foglia

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Cellulose Most abundant organic compound

on Earth

Page 21: MCC BP Based on work by K. Foglia  Chapter 5. Macromolecules.

MCC BPBased on work by K. Foglia

www.kimunity.com

Glycemic index Which food will get into your

blood more quickly? apple rice cakes corn flakes bagel peanut M&M

Page 22: MCC BP Based on work by K. Foglia  Chapter 5. Macromolecules.

MCC BPBased on work by K. Foglia

www.kimunity.com

Glycemic index Ranking of carbohydrates based on their

immediate effect on blood glucose (blood sugar) levels

Carbohydrate foods that breakdown quickly during digestion have the highest glycemic indices. Their blood sugar response is fast & high.

Page 23: MCC BP Based on work by K. Foglia  Chapter 5. Macromolecules.

MCC BPBased on work by K. Foglia

www.kimunity.com

Glycemic index Which food will get into your

blood more quickly? apple 36 rice cakes 82 corn flakes 84 bagel 72 peanut M&M33

Page 24: MCC BP Based on work by K. Foglia  Chapter 5. Macromolecules.

MCC BPBased on work by K. Foglia

www.kimunity.com

Let’s build some

Carbohydrates!