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MCBG-2011 At-a-Glance Course Schedule
Lectures are 60 minutes unless otherwise noted in bold times.
*This material covered on Exam 2; **This material covered on Exam 3.
Month Monday Tuesday Wednesday Thursday Friday
August 1 8:30-9:00
Intro to MCBG
Simmons/Frankfater
9:00-1:00
Amino acids,
peptides, &
polypeptides.
Schultz (90 min)
SGPSS
2 8:00-12:00
3-D structure of
proteins.
Schultz (90 min)
SGPSS
3 1:30-5:30
Protein function.
Schultz (90 min)
SGPSS
4 9:00 – 1:00
Enzyme Kinetics
Schultz (90 min)
SGPSS
5 8:00-12:00
Organization &
packaging of
chromosomes.
Zeleznik-Le (90 min) SGPSS
12:00-1:00 (optional)
Weekly Q & A – Rm. 360
August 8 9:00-1:00
DNA replication.
Introduction to
mitosis.
Zeleznik-Le (90 min)
SGPSS
9 8:00-12:00
Recombinant DNA
Techniques.
Foreman (90 min) SGPSS
10 1:30-5:30
DNA repair &
recombination.
Introduction to
meiosis.
Dingwall (90 min)
SGPSS
11 9:00-1:00
RNA synthesis &
processing.
Foreman (90 min) SGPSS
12 9:30-1:00
Protein synthesis.
Foreman.
SGPSS 1:00-2:00 (optional)
Weekly Q & A – Rm. 360
August 15 9:00-12:30
Transcription
Regulation I.
Schultz
SGPSS
16 8:00-12:00
Transcription
Regulation II.
Schultz (90 min)
SGPSS
17 1:30-5:30
Posttranscriptional
Gene Regulation.
Frankfater (90 min)
SGPSS
18 8:30-12:00 * Cytogenetics
Principles.
Frankfater (90 min)
SGPSS
19 9:30-10:30
Clinical Cytogenetics. Jones
10:30-12:00 (optional)
Weekly Q & A – Rm. 360
August 22 8:30-12:30
Exam 1
23 8:00-11:30
Patterns of single
gene inheritance.
Le Poole
SGPSS
24 1:30-5:30
Genetic variations
in individuals and
populations.
Le Poole (90 min)
SGPSS
25 8:30-12:30
Genetics of complex
diseases.
Frankfater (90 min)
SGPSS
26 9:30-1:30
Membranes I & II. Cukierman (120 min)
SGPSS
2:00-3:00 (optional)
Weekly Q & A – Rm. 460
August/
September
29 8:30-12:00
Electrical
properties of
membranes.
Cukierman SGPSS
30 8:00-11:30
Mitochondrial ATP
synthesis.
Cukierman
SGPSS
31 11:30-12:30
Required Genetics
Project Meeting
(Room 390).
1:30-5:30
Intracellular
compartments I&II
Frankfater (120 min) SGPSS
1 9:00-12:30
Vesicular
trafficking.
Frankfater
SGPSS
2 9:00-12:30
Lysosomal biogenesis,
endocytosis & secretion.
Frankfater
SGPSS 12:30-1:30 (optional)
Weekly Q & A – Rm. 360
September 5
Labor Day
6 8:00-12:00
**Introduction to
Histology/Micro-
scopic views of
organelles.
Campbell/Kovacs
(120 min)
**LAB
7 1:30-5:30
*Cell junctions &
Extracellular
matrix
Manteuffel (120 min)
SGPSS
8 8:30-12:30
*Cytoskeleton I&II. Denning (120 min)
**LAB
9 9:30-12:00
** Histology:
The epithelium. Clancy
**LAB 12:00-1:00 (optional)
Weekly Q & A – Rm. 360
September 12 8:30-12:30
Exam 2
13 8:00-11:00
Histo: Extracellular
matrix; Connective
Tissue.
Clancy
LAB
14 1:30-5:30
Cell signaling I.
Simmons
SG: Genetics project
planning.
15 8:30-12:30
Cell signaling II.
Simmons SGPSS
16 9:30-1:30
Histo: Bone & cartilage. Callaci (120 min) LAB
September 19 8:30-12:00
Cell Cycle I.
Schultz SGPSS
20 8:00-11:30
Cell Cycle II-
Mitosis.
Schultz
SGPSS
21 11:30-1:15 and
2:00-3:45
(assigned rooms)
Student Genetics
Presentations
22 8:30-12:30
Histo: Skin & oral
cavity
Clinical: Skin
disorders. Clancy (120 min)
LAB
23 9:30-1:30
Cell Cycle III-
Apoptosis
Schultz (90 min)
SGPSS
2:30-3:30 (optional)
Weekly Q & A –Rm. 360
September
26 8:30-12:00
Cancer Molecular
Genetics I.
Schultz (90 min) SGPSS
27 1:30-5:00
Cancer Molecular
Genetics II.
Schultz (90 min)
SGPSS
28 1:30-5:30 Pre-Exam Review
Histology Review
(optional)
29
Study Day
30 8:00-12:00
Exam 3
Written and
Histology Practical
Molecular Cell Biology & Genetics - 2011
1
MOLECULAR CELL BIOLOGY & GENETICS – 2011
Course Description
CONTENTS
Page
1. Competency-Based Goals and Outcome Objectives…………………………………… 1
Write a short paragraph addressing the following questions:
1. Please review the goals and expectations you wrote in the precourse self-assessment for the
4 competencies that are evaluated for this course. What have you done to achieve your goals and
expectations for this course? Are you achieving your goals and expectations for this course?
Why or why not? ______________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________
2. If you wish to revise your goals and/or expectations, please describe them in a short paragraph. __________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________
3. What do you plan to do in order to better meet your goals and expectations for this course?
STUDENT (and GROUP #) being assessed: DATE: ASSESSOR:
Instructions: Ongoing feedback: Evaluate yourself, another group member, or your group as a whole by using the criteria listed in the table. This form can be used for daily or weekly feedback on group dynamics. This student version of the form differs from that used by faculty facilitators in that it attempts to make explicit the kinds of behaviors that individual members of a successful small group are likely to display. Part I of the form identifies activities that are likely to promote a successful solution to the problem that the group is addressing. They are listed in the approximate order in which the activities should occur. Part II identifies non-verbal communication skills and behaviors that contribute to a successful small group and that are likely to maximize the satisfaction of individual group members. Circle the number to the right of each outcome objective that best represents your judgment for the activity described.
3 = Observed to a significant extent; at or above expected level (corresponds to ‘meets expectations’). 2 = Observed to a moderate extent; expected behavior inconsistently demonstrated (corresponds to ‘meets
expectations with concerns’). 1 = Observed to a small extent; needs improvement (corresponds to ‘does not meet expectations’).
Part 1. Communication and Problem Solving
COMMUNICATION (Opening)
Greeting:
Acknowledges each group member at the beginning of the session in a positive manner 1 2 3
Calibration:
Brief chat with other group members to assess potential barriers to communication (e.g., no sleep, illness, not prepared, etc.)
1 2 3
COMMUNICATION (Gathering information)
Goal Setting:
Reads problem before beginning 1 2 3
Discusses problem-solving goals and priorities 1 2 3
Questioning:
Starts with open-ended question to review relevant information (e.g., Can we review topic A because it seems relevant to this problem?)
1 2 3
Progresses to focused questions to request specific information pertaining to the problem (e.g., Can anyone define the term --------- in this problem? or How do we interpret this figure?
1 2 3
COMMUNICATION (Achieving a solution)
Problem Content:
Explicitly assures that everyone has the same understanding of terms and concepts 1 2 3
Identifies pertinent data to be analyzed 1 2 3
Knowledge:
Acknowledges opinion versus fact 1 2 3
Process:
Attempts to obtain information/opinions from all group members 1 2 3
Uses flip chart for diagrams, lists, etc., to keep process group-centered 1 2 3
Avoids side discussions with other group members 1 2 3
Encourages group to reach agreement by consensus 1 2 3
FORM 3 SMALL GROUP ASSESSMENT STUDENT VERSION
Molecular Cell Biology & Genetics - 2011
Part 2. Skills and Behaviors
COMMUNICATION SKILLS (Non-verbal)
Eye Contact:
Uses eye contact to convey interest and attentiveness 1 2 3
Body Language:
Uses posture (upright), gestures (e.g. nodding) and sounds (e.g. “mmhmm) to convey interest, understanding, and encouragement
1 2 3
Silences:
Pauses (three or more seconds) to give others a chance to speak 1 2 3
Refrains from interrupting others 1 2 3
RELATIONSHIP SKILLS:
Respect:
Open and honest about own strengths and weaknesses (knowledge, skills, attitudes) 1 2 3
Values others by acknowledging their efforts and contributions 1 2 3
Respectful of others’ opinions and point of view 1 2 3
Partnership:
Willingness to be helpful and work together 1 2 3
GROUP SKILLS
Ground Rules:
Refers to ground rules to guide individual and group behavior 1 2 3
Evaluation:
Promotes and participates in regular group evaluation. (“How effective was our problem-solving process.?” “Did we address all the issues relevant to the problems?” “Where can we improve?” NOT “Were the problems solved?”)
1 2 3
Participates in the evaluation of individual group members in a constructive and respectful manner
1 2 3
Conflict Resolution:
Identifies areas of conflict and initiates strategies (discussion, resources, etc.) for resolving disputes in a timely manner
1 2 3
PROFESSIONALISM Demeanor:
Conduct and dress is appropriate for the learning situation and does not distract from the group work
1 2 3
Conduct:
Punctuality (arrives promptly, avoids keeping group waiting); explains lateness or absence; informs group of known future absences
1 2 3
Honesty (admits errors, acknowledges any weaknesses or lack of preparation) 1 2 3
Preparation:
Prepares for SGPSS by reading, attending lectures, and preparing learning objectives 1 2 3
PERSONAL DEVELOPMENT
Evaluates own performance in small group 1 2 3
Evaluates own performance in MCBG, sets goals, and devises strategies to achieve them 1 2 3
COMMENTS: STUDENTS: If using this form to self-assess, write what you think you do well and what you’d like to improve. Share this with your group members. If assessing another group member, write what you think that person does well and what they could improve (be specific). Share this assessment with the other group members.
Instructions: If you observe any of the following problems, please indicate this with a checkmark. Follow the student’s behavior throughout the course. Indicate in the “Remediation” box what you have done to try to help the student and group improve.
Instructions: At the end of the course, both facilitators should get together and provide a final assessment of each student’s performance in small group. Using the criteria below, circle the appropriate number to the right. 3 = Meets expectations - observed to a significant extent; ability at or above expected level.
2 = Meets expectations with concerns - observed to a moderate extent; behavior inconsistently demonstrated. 1 = Does not meet expectations - observed to a small extent; needs improvement.
The final assessment rating should reflect improvements that were made and/or abilities that were maintained at expected levels. The assumption is that all students will be “3,” i.e., at the expected level or better. Lower ratings must be supported by specific comments that justify the rating. Turn this form in to the course directors.
COMMENTS:
COMMUNICATION: Uses verbal language effectively: 1 2 3
Helps to initiate the discussion.
Helps identify alternative solutions and discusses relative merits of each.
Promotes and participates in discussion to reach agreement by consensus.
COMMUNICATION: Uses effective listening skills and elicit and provide information using effective nonverbal, explanatory, and questioning skills:
1 2 3
Demonstrates interest and understanding.
Refrains from interrupting others. Encourage others to participate by waiting to comment.
Attempts to obtain information and opinions from all group members.
Regularly restates to clarify and/or indicate understanding.
Explicitly assures that everyone has same understanding of terms and concepts.
COMMUNICATION: Uses written language effectively: 1 2 3 Use flip chart and/or board for diagrams, lists, etc. to keep process group-centered and open to
other learning styles.
COMMUNICATION: Facilitates the learning of other students, including giving effective feedback:
1 2 3
Provides constructive, meaningful and nonthreatening verbal feedback to others in the group.
PROBLEM SOLVING: Demonstrates an investigatory and analytic thinking approach: 1 2 3 Participates in the definition of problem-solving goals before offering possible solutions.
Contributes to the identification and evaluation of pertinent data to be analyzed and alternative problem-solving strategies.
PROFESSIONALISM: Behaves professionally: 1 2 3
Preparation (comes to the small group problem-solving session prepared)
Punctuality (explains lateness or absence; informs of known future absences)
Honesty (admits errors, acknowledges any weaknesses or lack of preparation)
Respect (acknowledges the efforts and contributions of others).
PROFESSIONALISM: Interacts effectively with other small group members: 1 2 3 Refers to/obeys Group Ground Rules governing behaviors that promote group effectiveness
Identifies areas of conflict and initiates strategies (discussion, resources, etc.) for resolving conflicts in a timely manner.
FORM 4B END-OF-COURSE ASSESSMENT (Facilitators)
Molecular Cell Biology & Genetics - 2011
MEDICAL GENETICS PRESENTATION ASSESSMENT
GROUP NO: _______TITLE___________________________________________________________________ ASSESSOR: (students can remain anonymous) ___________________________________________________ Instructions for Individual Assessment: For each student, provide a Global Rating for each main category (white box) using the
following scale: 3 = Meets expectations 2 = Meets expectations with concern
1 = Does not meet expectations
Individual Presentation Attributes
Student Name
Communication - Verbal
Identified themselves by name
Clear introduction, middle, and conclusion.
Effectively explained important features of each slide.
Effectively used pointer to keep audience focused.
Clear voice (loudness, no mumbling) throughout presentation.
Rate of speech appropriate throughout presentation.
Varied voice intonations to keep audience interest.
Demonstrated no nervous habits that distracted from presentation.
Did not read notes excessively or at all.
Communication - PowerPoint Slides
Each slide had a clear title that identified a single main idea
Key words were used in place of lengthy sentences
Pictures, graphics, etc. were used to focus attention and emphasize concepts
Professionalism
Appropriate dress and grooming.
Attributed sources where appropriate.
Demonstrated respect for audience.
Group Presentation Rating
Presentation had a clear organizing theme, with clear main ideas and overall conclusion.
Relationships between the topics within the presentation were clearly explained and made sense.
All slides within presentation had a consistent background/theme.
Each presenter understood the previous and subsequent presentations and how they related to their own topic.
Enthusiasm for presentation was high and maintained throughout presentation.
Group effectively involved the audience in active learning.
Presentation took up the time allotted (not too long or too short)
FORM 5
Put a checkmark in a gray box where the student needs specific improvement.
Molecular Cell Biology & Genetics -2011
Student Name ______________________________________________Group No.________ PART A: PRESENTATION (based on faculty evaluations – Form 5 – of the genetics presentation) Competency: Interpersonal and Communication Skills Outcomes Assessed:
Use written and verbal language effectively.
Use information technology to manage information and communicate findings to other students.
Facilitate the learning of other students.
Communicate essential information effectively.
Competency: Professionalism
Outcomes Assessed:
Behave professionally. Abilities: Possible Points Points Earned Communication – Verbal (teaching fellow students)
Communicated effectively: 2
Worked effectively as part of a group (group rating) 2
Communication – PowerPoint Slides 3 Professionalism 3
TOTAL 10
PART B: RESEARCH and ANALYSIS (based on submitted annotated bibliography)
Competency: Lifelong Learning, Problem-solving, and Personal Growth
Outcomes Assessed:
Locate, appraise, critically review and assimilate evidence from scientific studies and medical literature.
Use information technology learning resources to manage basic science information, access online information, and support your own education.
Demonstrate an investigatory and analytic thinking approach.
Abilities: Possible Points
Points Earned
Write an annotated bibliography that demonstrates an effective use of information technology.
Provide 8-10 citations from a variety of sources. 2
Briefly indicate the key information in each reference. 2
Describe how you found each reference. 2
Indicate search terms used, and how the search was narrowed. 2
Document that each reference is current and reliable. 2
TOTAL 10
FORM 6 COURSE-DIRECTORS’ GRADE SHEET: MEDICAL GENETICS PROJECT
Explanation of the evaluation form: This form documents the performance of the student as it relates to the four core competencies that are measured in the Molecular Cell Biology and Genetics Course. The evaluation key is as follows:
3 = Meets expectations 2 = Meets expectations with concerns 1 = Does not meet expectations
This form was filled out by the course directors using a variety of data generated during the course. Medical Knowledge was assessed by three multiple-choice exams and a laboratory practical exam. Interpersonal and Communication Skills as well as Professionalism were evaluated based on final written reports by faculty facilitators of the Small Group Problem Solving Sessions and from faculty critiques of the Medical Genetics Project oral presentations. The Life-long Learning, Problem-solving, and Personal Growth competency was assessed from the student’s written reports of their literature search for the Medical Genetics Project, and from written reports by faculty Small Group facilitators on problem-solving skills and self-assessment and goal-setting behavior. Any competency evaluation score that is less than 3 is supported by a short paragraph that provides specific examples that explain the basis of the assessment.
MEDICAL KNOWLEDGE 1 2 3
Has a knowledge of fundamental facts and principles of Protein Structure-Function, Molecular Biology, Cell Biology, Genetics, and Histology
INTERPERSONAL AND COMMUNICATION SKILLS 1 2 3
Uses verbal language effectively.
Uses effective listening skills and elicits and provides information using effective nonverbal, explanatory, and questioning skills.
Uses written language effectively.
Facilitates the learning of other students, including giving effective feedback.
Communicates essential information effectively within their small group and with other students in the class.
PROFESSIONALISM, MORAL REASONING AND ETHICAL JUDGEMENT 1 2 3
Behaves professionally.
Interacts effectively with other small group members in the educational setting.
Recognizes and effectively deals with unethical behavior of other members of the class.
LIFELONG LEARNING, PROBLEM-SOLVING AND PERSONAL GROWTH 1 2 3
Is able to locate, appraise, critically review and assimilate evidence from scientific studies and medical literature.
Uses information technology learning resources to manage basic science information, access online information and support their own education.
Demonstrates an investigatory and analytic thinking approach in SGPSS and course projects.
Demonstrates a commitment to individual professional and personal growth.