MBV2010/BIO2140 Colloquium, April 9. RULES Multiple choice Only one correct answer 30-60 seconds to answer No textbook, computer, mobile phone, please.

MBV2010/BIO2140

Colloquium, April 9

RULES

• Multiple choice• Only one correct answer• 30-60 seconds to answer• No textbook, computer, mobile phone, please

There will be a prize for the group with the most correct answers.

Most small nuclear RNA genes are transcribed by

A RNA polymerase I

B RNA polymerase II

C RNA polymerase III

D RNA polymerase IV

1

Most small nuclear RNA genes are transcribed by

A RNA polymerase I

B RNA polymerase II

C RNA polymerase III

D RNA polymerase IV

1

The carboxy-terminal domain of RNApolymerase II consists of a repeated

A heptapeptide (7 repeats)

B hexapeptide (6 repeats)

C octapeptide (8 repeats)

D decapeptide (10 repeats)

2

The carboxy-terminal domain of RNApolymerase II consists of a repeated

A heptapeptide (7 aa)

B hexapeptide (6 aa)

C octapeptide (8 aa)

D decapeptide (10 aa)

2

Tyr-Ser-Pro-Thr-Ser-Pro-Ser

The human CTD consists of

A 27 repeats

B 32 repeats

C 45 repeats

D 52 repeats

3

Tyr-Ser-Pro-Thr-Ser-Pro-Ser

The human CTD consists of

A 27 repeats (yeast)

B 32 repeats (Caenorhabditis)

C 45 repeats (Drosophila)

D 52 repeats (humans)

3

Tyr-Ser-Pro-Thr-Ser-Pro-Ser

The TATA-binding protein (TBP) is part of

A Transcription factor IIA

B Transcription factor IIB

C Transcription factor IID

D Transcription factor IIE

4

The TATA-binding protein (TBP) is part of

A Transcription factor IIA

B Transcription factor IIB

C Transcription factor IID

D Transcription factor IIE

4

FACT is a protein complex involved in

A Transcription

B Replication

C Translation

D Recombination

5

?

FACT is a protein complex involved in

A Transcription

B Replication

C Translation

D Recombination

5

FACT = facilitates chromatin transcription

The rho protein mediates

A Initiation of transcription

B Initiation of replication

C Site-specific recombination

D Termination of transcription

6

The rho protein mediates

A Initiation of transcription

B Initiation of replication

C Site-specific recombination

D Termination of transcription

6

Which type of intron does not require abranch site for splicing?

A Group I introns

B GU-AG introns

C AU-AC introns

D Group II introns

7

Which type of intron does not require abranch site for splicing?

A Group I introns

B GU-AG introns

C AU-AC introns

D Group II introns

7

Which of the following proteins plays a role in splice site selection?

A snRNPs

B SR proteins

C Sxl protein

D U2

8

Which of the following proteins plays a role in splice site selection?

A snRNPs

B SR proteins

C Sxl protein

D U2

8

Amino acids are linked to tRNAs at

A the 5’ terminus of tRNAs

B the adenine base at the 3’ terminus

C the ribose at the 3’ terminus

D the phosphate linking the 3’ terminal nucleotides of tRNAs

9

Amino acids are linked to tRNAs at

A the 5’ terminus of tRNAs

B the adenine base at the 3’ terminus

C the ribose at the 3’ terminus

D the phosphate linking the 3’ terminal nucleotides of tRNAs

9

Which of the following components of thetranslation machinery has proofreadingcapability?

A ribosomal RNAs

B ribosomal proteins

C translation initiation factors

D tRNA synthetases

10

Which of the following components of thetranslation machinery has proofreadingcapability?

A ribosomal RNAs

B ribosomal proteins

C translation initiation factors

D tRNA synthetases

10

Peptide bond formation is catalyzed by

A ribosomal RNA

B ribosomal proteins

C translation factors

D all of the above

11

Peptide bond formation is catalyzed by

A ribosomal RNA

B ribosomal proteins

C translation factors

D all of the above

11