Material Safety Data Sheet

Material Safety Data SheetPhenol, Reagent ACS

ACC# 01188

Section 1 - Chemical Product and Company IdentificationMSDS Name: Phenol, Reagent ACS Catalog Numbers: AC417170000, AC417170250, AC417175000 Synonyms: Carbolic acid; Phenylic acid; Hydroxybenzene; Monohydroxybenzene; Phenyl hydroxide Company Identification: Acros Organics N.V. One Reagent Lane Fair Lawn, NJ 07410For information in North America, call: 800-ACROS-01For emergencies in the US, call CHEMTREC: 800-424-9300

Section 2 - Composition, Information on Ingredients

CAS# Chemical Name Percent EINECS/ELINCS

108-95-2 Phenol ca.100 203-632-7

Hazard Symbols: T Risk Phrases: 34 24/25

Section 3 - Hazards Identification

EMERGENCY OVERVIEW

Appearance: colourless. Flash Point: 79 deg C. Danger! Corrosive. May cause central nervous system effects. May cause liver and kidney damage. Harmful if swallowed or absorbed through the skin. May be harmful if inhaled. Combustible liquid and vapor. May cause central nervous system depression. Causes eye and skin burns. May cause severe respiratory tract irritation with possible burns. May cause severe digestive tract irritation with possible burns. This substance has caused adverse reproductive and fetal effects in animals. Target Organs: Kidneys, central nervous system, liver.

Potential Health Effects Eye: Contact with liquid or vapor causes severe burns and possible irreversible eye damage. May cause chemical conjunctivitis and corneal damage.Skin: Harmful if absorbed through the skin. Direct skin contact results in white, wrinkled discoloration, followed by severe burns. Phenol solutions may be absorbed through the skin ra pidly to cause systemic poisoning and possible death. Ingestion: Harmful if swallowed. May cause severe and permanent damage to the digestive tract. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure. May cause perforation of the digestive tract. Causes digestive tract burns with immediate pain, swelling of the throat, convulsions, and possible coma. Inhalation: Causes severe irritation of upper respiratory tract with coughing, burns, breathing difficulty, and possible coma. May be fatal if exposed to high concentrations. Aspiration may lead to pulmonary edema. May also cause pallor, loss of appetite, nausea, vomiting, diarrhea, weakness, darkened urine, headache, sweating, convulsions,

cyanosis, unconsciousness, fatigue, pulmonary edema and coma. Inhalation at high concentrations may cause CNS depression and asphixiation. Chronic: Chronic inhalation and ingestion may cause effects similar to those of acute inhalation and ingestion. May cause liver and kidney damage. May cause reproductive and fetal effects. Effects may be delayed. Laboratory experiments have resulted in mutagenic effects. Repeated skin contact may cause dermatitis with dark pigmentation of the skin. Animal studies have reported the development of tumors.

Section 4 - First Aid Measures

Eyes: Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed. Extensive irrigation with water is required (at least 30 minutes). Skin: Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Discard contaminated clothing in a manner which limits further exposure. SPEEDY ACTION IS CRITICAL! Destroy contaminated shoes. Ingestion: Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. Inhalation: Get medical aid immediately. Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.Notes to Physician: Persons with liver or kidney disease should not be exposed to phenol for any length of time. Antidote: Activated charcoal, followed by cathartic, may be preferred to ipecac induced emesis or lavage in decontamination of the GI tract and preventing systemic absorption of phenol.

Section 5 - Fire Fighting Measures

General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Combustible Liquid. Containers may explode when heated. Extinguishing Media: In case of fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Use agent most appropriate to extinguish fire.

Section 6 - Accidental Release Measures

General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Clean up spills immediately, observing precautions in the Protective Equipment section. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation.

Section 7 - Handling and Storage

Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well-ventilated area. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be

dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Do not ingest or inhale. Discard contaminated shoes. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Storage: Keep away from heat, sparks, and flame. Keep away from sources of ignition. Keep container closed when not in use. Store in a tightly closed container. Keep from contact with oxidizing materials. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep refrigerated. (Store below 4°C/39°F.)

Section 8 - Exposure Controls, Personal Protection

Engineering Controls: Use explosion-proof ventilation equipment. Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits. Exposure Limits

Chemical Name ACGIH NIOSH OSHA - Final PELs

Phenol5 ppm TWA; skin - potential for cutaneous absorption

5 ppm TWA; 19 mg/m3 TWA 250 ppm IDLH

5 ppm TWA; 19 mg/m3 TWA

OSHA Vacated PELs: Phenol: 5 ppm TWA; 19 mg/m3 TWA Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear neoprene gloves, apron, and/or clothing. Selection of specific glove materials should be based on your conditions of use in your application in consultation with your Safety Officer and manufacturer's glove recommendations. Many factors influence the determination of proper glove material such as permeation rates and break through time. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: A respiratory protection program that meets OSHA's 29 CFR §1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Section 9 - Physical and Chemical Properties

Physical State: Liquid Appearance: colourless Odor: Sweet and tarry odor. pH: Not available. Vapor Pressure: 0.35 mm Hg @ 25 deg C Vapor Density: 3.2 Evaporation Rate:<0.01 (butyl acetate=1) Viscosity: Not available. Boiling Point: 192 deg C @ 760.00 mmHg Freezing/Melting Point:43 deg C Autoignition Temperature: 605 deg C ( 1,121.00 deg F) Flash Point: 79 deg C ( 174.20 deg F) Decomposition Temperature:Not available. NFPA Rating: (estimated) Health: 4; Flammability: 2; Reactivity: 0 Explosion Limits, Lower:1.30 vol % Upper: 9.50 vol % Solubility: Soluble. Specific Gravity/Density:1.0600g/cm3 Molecular Formula:C6H6O Molecular Weight:94.11

Section 10 - Stability and Reactivity

Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: Incompatible materials, ignition sources, excess heat. Incompatibilities with Other Materials: Strong oxidizing agents, acids, isocyanates, acetaldehyde, nitrides (e.g. potassium nitride, sodium nitride), calcium hypochlorite, peroxomonosulfuric acid, nitrobenzene, sodium nitrite, aluminum chloride, peroxydisulfuric acid, 1,3-butadiene, boron trifluoride diethyl ether. Hazardous Decomposition Products: Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide. Hazardous Polymerization: Has not been reported.

Section 11 - Toxicological Information

RTECS#: CAS# 108-95-2: SJ3325000 LD50/LC50:CAS# 108-95-2:Draize test, rabbit, eye: 5 mg Severe;Draize test, rabbit, skin: 500 mg/24H Severe;Draize test, rabbit, skin: 100 mg Mild;Inhalation, mouse: LC50 = 177 mg/m3;Inhalation, rat: LC50 = 316 mg/m3;Oral, mouse: LD50 = 270 mg/kg;Oral, rat: LD50 = 317 mg/kg;Skin, rabbit: LD50 = 630 mg/kg;Skin, rat: LD50 = 669 mg/kg;<br. Carcinogenicity:CAS# 108-95-2: ACGIH: A4 - Not Classifiable as a Human Carcinogen IARC: Group 3 carcinogen Epidemiology: Administration onto the skin, mouse: TDLo = 16 gm/kg/40W-I (Tumorigenic - Carcinogenic by RTECS criteria - S kin and Appendages - tumors). Teratogenicity: Oral, rat: TDLo = 1200 mg/kg (female 6-15 day(s) after conception) Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus).; Oral, mouse: TDLo = 4 gm/kg (female 6-15 day(s) after conception) Specific Developmental Abnormalities - musculoskeletal system. Reproductive Effects: Oral, rat: TDLo = 300 mg/kg (female 6-15 day(s) after conception) Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants). Neurotoxicity: No data available. Mutagenicity: Mutation Test Systems - not otherwise specified: Human, HeLa cell = 17 mg/L.; DNA Inhibition: Human, HeLa cell = 1 mmol/L.; Mutation Test Systems - not otherwise specified: Human, Lymphocyte = 5 umol/L.; Sister Chromatid Exchange: Human, Lymphocyte = 5 umol/L. Other Studies: Standard Draize Test: Administration onto the skin (rabbit) = 500 mg/24H (Severe). Standard Draize Test: Administra tion into the eye (rabbit) = 5 mg (Severe).</br.

Section 12 - Ecological Information

Ecotoxicity: Water flea Daphnia: EC50=12 mg/l; 48-hour; CAS# 108-95-2: Unspecified flea Daphnia: EC50=4.0 mg/l; 96-hour; CAS# 108-95-2: Unspecified Fathead Minnow: LC50 > 50 mg/l; 1 Hr; CAS# 108-95-2 Static @ 18-22°C Fathead Minnow: TLm = 41 mg/L;

48-hour; CAS# 108-95-2: Flow-through @ 15°C Bluegill/Sunfish: TLm = 19 / 5.7 mg/L; 96 Hr; CAS# 108-95-2: Flow-through If released to the environment, phenol's primary removal mechanism is biodegradation which is generally rapid (days). If phenol is released to soil, it will readily leach and biodegrade. The biodegradation in soil is generally rapid with half-lives of under 5 days even in subsurface soils. Environmental: Phenol does not bioconcentrate in aquatic organisms. In the atmosphere, phenol occurs as a vapor and reacts with photochemically-produced hydroxyl radicals resulting in a half-life of approximately 15 hours. During the nighttime, it reacts with nitrate radicals with a resulting half-life of 12 minutes. Phenol has also been shown to be readily removed from the atmosphere by rain. Physical: No information available. Other: No information available.

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification. RCRA P-Series: None listed. RCRA U-Series: CAS# 108-95-2: waste number U188.

Section 14 - Transport Information

US DOT IATA RID/ADR IMOCanada

TDG

Shipping Name: PHENOL,SOLID PHENOL

Hazard Class: 6.1 6.1(9.2)

UN Number: UN1671 UN1671

Packing Group: II II

Section 15 - Regulatory Information

US FEDERAL

TSCA CAS# 108-95-2 is listed on the TSCA inventory. Health & Safety Reporting ListCAS# 108-95-2: Effective date: June 1, 1987; Sunset Date: June 1, 1997 Chemical Test RulesNone of the chemicals in this product are under a Chemical Test Rule. Section 12bNone of the chemicals are listed under TSCA Section 12b. TSCA Significant New Use RuleNone of the chemicals in this material have a SNUR under TSCA. SARA

Section 302 (RQ)CAS# 108-95-2: final RQ = 1000 pounds (454 kg) Section 302 (TPQ)CAS# 108-95-2: TPQ = 500/10,000 pounds; RQ = 1000 pounds SARA CodesCAS # 108-95-2: acute, chronic, flammable. Section 313This material contains Phenol (CAS# 108-95-2, 100%),which is subject to the reporting requirements of Section 313 of SARA Title III and 40 CFR Part 373. Clean Air Act:

CAS# 108-95-2 is listed as a hazardous air pollutant (HAP). This material does not contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone depletors. Clean Water Act:CAS# 108-95-2 is listed as a Hazardous Substance under the CWA. CAS# 108-95-2 is listed as a Priority Pollutant under the Clean Water Act. CAS# 108-95-2 is listed as a Toxic Pollutant under the Clean Water Act. OSHA:None of the chemicals in this product are considered highly hazardous by OSHA. STATECAS# 108-95-2 can be found on the following state right to know lists: California, New Jersey, Florida, Pennsylvania, Minnesota, Massachusetts. California No Significant Risk Level: None of the chemicals in this product are listed. European/International RegulationsEuropean Labeling in Accordance with EC DirectivesHazard Symbols:T Risk Phrases:R 34 Causes burns. R 24/25 Toxic in contact with skin and if swallowed.

Safety Phrases:S 1/2 Keep locked up and out of reach of children. S 28 After contact with skin, wash immediately with... S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).

Material Data Safety Sheet (MSDS): Acetic Acid

1. Product Identification 7. Handling and Storage

2. Composition 8. Exposure Controls/Personal Protection

3. Hazards Identification 9. Physical and Chemical Properties

4. First Aid Measures 10. Stability and Reactivity 5. Fire Fighting Measures 11. Toxicological Information 6. Accidental Release Measures 12. Ecological Information 13. Disposal Considerations 16. Other Information

Note: This information sheet has been re-formatted for better clarity by the Department of Earth Sciences.Some of the data such as information on shipping and weapons treaties were intentionally left out. If youwant to look at the complete MSDS, you can either check one of the hardcopy versions in the Department,contact the manufacturer, or check one of the various Web-based databases such as those compiledby BU's Office of Environmental Health & Safety (www.bu.edu/ehs/msds/index.htm). Return to MSDS Index

1. Product Identification

ACETIC ACID, GLACIAL

MSDS Number: A0326 --- Effective Date: 09/24/97

Synonyms: Acetic acid, methane carboxylic acid; ethanoic acid CAS No.: 64-19-7 Molecular Weight: 60.05 Chemical Formula: CH3COOH Top of Page MSDS Index

2. Composition/Information on Ingredients

Ingredient CAS # Percent Hazardous?

Acetic Acid 64-19-7 100 YesTop of Page MSDS Index

3. Hazards Identification

Emergency Overview -------------------------- POISON! DANGER! CORROSIVE. LIQUID AND MIST CAUSE SEVERE BURNSTO ALL BODY TISSUE. MAY BE FATAL IF SWALLOWED. HARMFUL IFINHALED. INHALATION MAY CAUSE LUNG AND TOOTH DAMAGE.FLAMMABLE LIQUID AND VAPOR.

J.T. Baker SAF-T-DATA(tm) Ratings (Provided here for your convenience) ----------------------------------------------------------------------------------------------------------- Health Rating: 2 - Moderate Flammability Rating: 2 - Moderate Reactivity Rating: 2 - Moderate Contact Rating: 3 - Severe (Corrosive) Lab Protective Equip: GOGGLES & SHIELD; LAB COAT & APRON; VENT HOOD; PROPERGLOVES; CLASS B EXTINGUISHER Storage Color Code: White Stripe (Store Separately) -----------------------------------------------------------------------------------------------------------

Potential Health Effects ----------------------------------

Inhalation: Inhalation of concentrated vapors may cause serious damage to the lining of the nose, throat, andlungs. Breathing difficulties may occur. Neither odor nor degree of irritation are adequate to indicatevapor concentration. Ingestion: Swallowing can cause severe injury leading to death. Symptoms include sore throat, vomiting, anddiarrhea. Ingestion of as little as 1.0 ml has resulted in perforation of the esophagus.

Skin Contact: Contact with concentrated solution may cause serious damage to the skin. Effects may includeredness, pain, skin burns. High vapor concentrations may cause skin sensitization. Eye Contact: Eye contact with concentrated solutions may cause severe eye damage followed by loss of sight.Exposure to vapor may cause intense watering and irritation to eyes. Chronic Exposure: Repeated or prolonged exposures may cause darkening of the skin, erosion of exposed front teeth,and chronic inflammation of the nose, throat, and bronchial tubes. Aggravation of Pre-existing Conditions: Persons with pre-existing skin disorders or eye problems, or impaired respiratory function may bemore susceptible to the effects of the substance. Top of Page MSDS Index

4. First Aid Measures

Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.Call a physician. Ingestion: DO NOT INDUCE VOMITING! Give large quantities of water or milk if available. Never giveanything by mouth to an unconscious person. Get medical attention immediately. Skin Contact: In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removingcontaminated clothing and shoes. Wash clothing before reuse. Call a physician.

Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelidsoccasionally. Get medical attention immediately. Top of Page MSDS Index

5. Fire Fighting Measures

Fire: Flash point: 40C (104F) CCAutoignition temperature: 427C (801F)Flammable limits in air % by volume: lel: 4.0; uel: 16.0Flammable Liquid and Vapor! Explosion: Above flash point, vapor-air mixtures are explosive within flammable limits noted above. Vapors canflow along surfaces to distant ignition source and flash back. Contact with strong oxidizers may causefire. Reacts with most metals to produce hydrogen gas, which can form an explosive mixture with air. Fire Extinguishing Media: Water, dry chemical, foam or carbon dioxide. Water spray may be used to keep fire exposedcontainers cool.

Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathingapparatus with full facepiece operated in the pressure demand or other positive pressure mode. Watermay be used to flush spills away from exposures and to dilute spills to non-flammable mixtures.Water diluted acid can react with metals to form hydrogen gas. Top of Page MSDS Index

6. Accidental Release Measures

Ventilate area of leak or spill. Remove all sources of ignition. Wear appropriate personal protectiveequipment as specified in Section 8. Isolate hazard area. Keep unnecessary and unprotected personnelfrom entering. Use water spray to dilute spill to a nonflammable mixture. Contain and recover liquidwhen possible. Collect liquid in an appropriate container or absorb with an inert

material (e. g.,vermiculite, dry sand, earth), and place in a chemical waste container. Use non-sparking tools andequipment. Do not use combustible materials, such as saw dust. Do not flush to sewer! USRegulations (CERCLA) require reporting spills and releases to soil, water and air in excess ofreportable quantities. The toll free number for the US Coast Guard National Response Center is (800)424-8802.

J. T. Baker NEUTRASORB(tm) or TEAM(tm) 'Low Na+' acid neutralizers are recommended forspills of this product.

Top of Page MSDS Index

7. Handling and Storage

Protect against physical damage. Store in a cool, dry well-ventilated location, away from any areawhere the fire hazard may be acute. Outside or detached storage is preferred. Separate fromincompatibles. Containers should be bonded and grounded for transfers to avoid static sparks. Storageand use areas should be No Smoking areas. Use non-sparking type tools and equipment, includingexplosion proof ventilation. Protect from freezing. Store above 17C (63 F). Containers of this materialmay be hazardous when empty since they retain product residues (vapors, liquid); observe allwarnings and precautions listed for the product.


8. Exposure Controls/Personal Protection

Airborne Exposure Limits: -OSHA Permissible Exposure Limit (PEL): 10 ppm (TWA).-ACGIH Threshold Limit Value (TLV): 10 ppm (TWA); 15 ppm (STEL).

Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures below theAirborne Exposure Limits. Local exhaust ventilation is generally preferred because it can control theemissions of the contaminant at its source, preventing dispersion of it into the general work area.Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices,most recent edition, for details. Personal Respirators (NIOSH Approved): If the exposure limit is exceeded, a full facepiece respirator with organic vapor cartridge may be wornup to 50 times the exposure limit or the maximum use concentration specified by the appropriateregulatory agency or respirator supplier, whichever is lowest. For emergencies or instances where theexposure levels are not known, use a full-facepiece positive-pressure, air-supplied respirator.WARNING: Air purifying respirators do not protect workers in oxygen-deficient atmospheres. Skin Protection: Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, asappropriate, to prevent skin contact. Eye Protection: Use chemical safety goggles and/or a full face shield where splashing is possible. Maintain eye washfountain and quick-drench facilities in work area.


9. Physical and Chemical Properties (Acetic Acid)

Appearance: Clear, colorless liquid.Odor: Strong, vinegar-like.Solubility: Infinitely soluble.Density: 1.05pH: 2.4 (1.0M solution)% Volatiles by volume @ 21C (70F):

100

Boiling Point: 118C (244F)

Melting Point: 16.6C (63F)Vapor Density (Air=1): 2.1Vapor Pressure (mm Hg): 11 @ 20C (68F)Evaporation Rate (BuAc=1): 0.97Top of Page MSDS Index

10. Stability and Reactivity

Stability: Stable under ordinary conditions of use and storage. Heat and sunlight can contribute to instability.Releases heat and toxic, irritating vapors when mixed with water. Acetic acid contracts slightly uponfreezing which may cause the container to burst. Hazardous Decomposition Products: Carbon dioxide and carbon monoxide may form when heated to decomposition. May also release toxicand irritating vapors. Hazardous Polymerization: Will not occur. Incompatibilities: Acetic Acid is incompatible with chromic acid, nitric acid, ethylene glycol, perchloric acid,phosphorous trichloride, oxidizers, sodium peroxide, strong caustics, most metals (except aluminum),carbonates, hydroxides, oxides, and phosphates. Conditions to Avoid: Heat, flame, ignition sources, freezing, incompatibles


11. Toxicological Information

Oral rat LD50: 3310 mg/kg; skin rabbit LD50: 1.06 g/kg; inhalation mouse LC50: 5620ppm/1-hr;investigated as a mutagen, reproductive effector. NTP Carcinogen

Ingredient Known Anticipated IARC Category

Acetic Acid (64-19-7) No No None


12. Ecological Information

Environmental Fate: When released into the air, this material may be moderately degraded by reaction with photochemicallyproduced hydroxyl radicals. When released into air, this material is expected to have a half-lifebetween 10 and 30 days. When released into water, this material is expected to readily biodegrade.When released into the water, this material is expected to have a half-life between 1 and 10 days.Standard dilution BOD5/TOD = 58% When released into the soil, this material is expected to readilybiodegrade. This material is not expected to significantly bioaccumulate. This material has an estimatedbioconcentration factor (BCF) of less than 100. Environmental Toxicity: This material is expected to be slightly toxic to aquatic life. The LC50/96-hour values for fish arebetween 10 and 100 mg/l.

For glacial acetic acid: EC50 (wheat fumigation) = 23.3 mg/m3/2-hr, effect: leaf injuryLC50 (shrimp) = 100 - 300 mg/l/48-hrLC50 (fathead minnow) = 88 mg/l/96-hrThis material may be toxic to aquatic life.


13. Disposal Considerations

Whatever cannot be saved for recovery or recycling should be handled as hazardous waste and sent toa RCRA approved waste facility. Processing, use or contamination of this product may change thewaste management options. State and local disposal regulations may differ from

federal disposalregulations. Dispose of container and unused contents in accordance with federal, state and localrequirements.


16. Other Information

NFPA Ratings: Health: 3 Flammability: 2 Reactivity: 0 Label Hazard Warning: POISON! DANGER! CORROSIVE. LIQUID AND MIST CAUSE SEVERE BURNS TO ALLBODY TISSUE. MAY BE FATAL IF SWALLOWED. HARMFUL IF INHALED. INHALATIONMAY CAUSE LUNG AND TOOTH DAMAGE. FLAMMABLE LIQUID AND VAPOR. Label Precautions: Do not get in eyes, on skin, or on clothing.Do not breathe vapor or mist.Keep container closed.Use only with adequate ventilation.Wash thoroughly after handling.Keep away from heat, sparks and flame. Label First Aid: In case of contact, immediately flush eyes or skin with plenty of water for at least 15 minutes whileremoving contaminated clothing and shoes. Wash clothing before reuse. If swallowed, DO NOTINDUCE VOMITING. Give large quantities of water. Never give anything by mouth to anunconscious person. If inhaled, remove to fresh air. If not breathing, give artificial respiration. Ifbreathing is difficult, give oxygen. In all cases get medical attention immediately. Product Use: Laboratory Reagent. Revision Information: MSDS Section(s) changed since last revision of document include: 10. Disclaimer:

iece airline respirator in the positive pressure mode with emergency escape provisions.

Section 9 - Physical and Chemical Properties

Physical State: Liquid Appearance: clear to yellow Odor: strong odor - acrid odor pH: 1.0 Vapor Pressure: 6.8 mm Hg Vapor Density: Not available. Evaporation Rate:Not available. Viscosity: Not available. Boiling Point: 122 deg C Freezing/Melting Point:-42 deg C Autoignition Temperature: Not available. Flash Point: Not available. Decomposition Temperature:Not available. NFPA Rating: (estimated) Health: 3; Flammability: 0; Reactivity: 1 Explosion Limits, Lower:Not available. Upper: Not available. Solubility: Soluble. Specific Gravity/Density:1.41 Molecular Formula:HNO3 Molecular Weight:63.01

Section 10 - Stability and Reactivity

Chemical Stability: Stable. Decomposes when in contact with air, light, or organic matter. Conditions to Avoid: High temperatures, incompatible materials, ignition sources, dust generation, moisture, combustible materials, reducing agents. Incompatibilities with Other Materials: Reducing agents, acids (organic, e.g. acetic acid, benzoic acid, formic acid, methanoic acid, oxalic acid), alcohols and glycols (e.g. butyl alcohol, ethanol, methanol, ethylene glycol), aldehydes (e.g. acetaldehyde, acrolein, chloral hydrate, formaldehyde), amides (e.g. butyramide, diethyltoluamide, dimethyl formamide), amines (aliphatic and aromatic, e.g. dimethyl amine, propylamine, pyridine, triethylamine), azo, diazo, and hydrazines (e.g. dimethyl hydrazine, hydrazine, methyl hydrazine), carbamates (e.g. carbanolate, carbofuran), caustics (e.g. ammonia, ammonium hydroxide, calcium hydroxide, potassium hydroxide, sodium hydroxide), cyanides (e.g. potassium cyanide, sodium cyanide), dithiocarbamates (e.g. ferbam, maneb, metham, thiram), esters (e.g. butyl acetate, ethyl acetate, propyl formate), ethers (e.g. dioxane, furfuran, tetrahydrofuran (THF)), fluorides (inorganic, e.g. ammonium fluoride, calcium fluoride, cesium fluoride), hydrocarbons (aromatic, e.g. benzene, chrysene, cumen. Hazardous Decomposition Products: Nitrogen oxides. Hazardous Polymerization: Has not been reported.

Section 11 - Toxicological Information

RTECS#: CAS# 7697-37-2: QU5775000; QU5900000 CAS# 7732-18-5: ZC0110000 LD50/LC50:

CAS# 7697-37-2:Inhalation, rat: LC50 = 67 ppm(NO2)/4H;<br. CAS# 7732-18-5:Oral, rat: LD50 = >90 mL/kg;<br. Carcinogenicity:CAS# 7697-37-2: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA. CAS# 7732-18-5: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA. Epidemiology: No information found. Teratogenicity: No information found. Reproductive Effects: No information found. Neurotoxicity: No information found. Mutagenicity: No information found. Other Studies: See actual entry in RTECS for complete information.</br.</br.

Section 12 - Ecological Information

Ecotoxicity: No data available. No information available. Environmental: Terrestial: During transport through the soil, nitric acid will dissolve some of the soil material, in particular, the carbonate based materials. The acid will be neutralized to some degree with adsorption of the proton also occurring on clay materials. However, significant amounts of acid are expected to remain for transport down toward the ground water table. Upon reaching the ground water table, the acid will continue to move, now in the direction of the ground water flow. Physical: Not expected to biodegrade or bioconcentrate. Other: For more information, see "HANDBOOK OF ENVIRONMENTAL FATE AND EXPOSURE DATA."

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification. RCRA P-Series: None listed. RCRA U-Series: None listed.

Section 14 - Transport Information

US DOT IATA RID/ADR IMOCanada

TDG

Shipping Name: NITRIC ACIDNITRIC ACID

Hazard Class: 8 8(9.2)

UN Number: UN2031 UN2031

Packing Group: II II

Section 15 - Regulatory Information

US FEDERAL

TSCA CAS# 7697-37-2 is listed on the TSCA inventory.

CAS# 7732-18-5 is listed on the TSCA inventory. Health & Safety Reporting ListNone of the chemicals are on the Health & Safety Reporting List. Chemical Test RulesNone of the chemicals in this product are under a Chemical Test Rule. Section 12bNone of the chemicals are listed under TSCA Section 12b. TSCA Significant New Use RuleNone of the chemicals in this material have a SNUR under TSCA. SARA

Section 302 (RQ)CAS# 7697-37-2: final RQ = 1000 pounds (454 kg) Section 302 (TPQ)CAS# 7697-37-2: TPQ = 1000 pounds; RQ = 1000 pounds SARA CodesCAS # 7697-37-2: acute, chronic, flammable. Section 313This material contains Nitric acid (CAS# 7697-37-2, 69 71%),which is subject to the reporting requirements of Section 313 of SARA Title III and 40 CFR Part 373. Clean Air Act:This material does not contain any hazardous air pollutants. This material does not contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone depletors. Clean Water Act:CAS# 7697-37-2 is listed as a Hazardous Substance under the CWA. None of the chemicals in this product are listed as Priority Pollutants under the CWA. None of the chemicals in this product are listed as Toxic Pollutants under the CWA. OSHA:CAS# 7697-37-2 is considered highly hazardous by OSHA. STATECAS# 7697-37-2 can be found on the following state right to know lists: California, New Jersey, Florida, Pennsylvania, Minnesota, Massachusetts. CAS# 7732-18-5 is not present on state lists from CA, PA, MN, MA, FL, or NJ. California No Significant Risk Level: None of the chemicals in this product are listed. European/International RegulationsEuropean Labeling in Accordance with EC DirectivesHazard Symbols:O C Risk Phrases:R 35 Causes severe burns. R 8 Contact with combustible material may cause fire.

Safety Phrases:S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36 Wear suitable protective clothing. S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). S23B Do not breathe fumes.

WGK (Water Danger/Protection)CAS# 7697-37-2: 1 CAS# 7732-18-5: No information available. CanadaCAS# 7697-37-2 is listed on Canada's DSL List. CAS# 7697-37-2 is listed on Canada's

DSL List. CAS# 7732-18-5 is listed on Canada's DSL List. CAS# 7732-18-5 is listed on Canada's DSL List.

2,4,6-Trinitro- Phenol

Section 1 - Chemical Product

MSDS Name: Picric Acid Reagent ACS Material

Safety Data Sheet

Synonym:Trinitrophenol; Picronitric acid; 2,4,6-

Trinitrophenol; 2,4,6-Trinitrophenyl; Picronitric aci

Section 2 - COMPOSITION, INFORMATION ON

INGREDIENTS

name:Phenol, 2,4,6-Trinitro-

CAS:88-89-1

content:ca 100%

EINECS:201-865-9

Hazard Symbols: T E

Risk Phrases: 2 23/24/25 4 43

Section 3 - HAZARDS IDENTIFICATION

EMERGENCY OVERVIEW

Risk of explosion by shock, friction, fire or other

sources of ignition. Toxic by inhalation, in contact

with skin and if swallowed.

Forms very sensitive explosive metallic compounds.

May cause sensitization by skin contact.

Potential Health Effects

Eye:

Causes eye irritation. May result in corneal injury.

Skin:

Causes skin irritation. May cause skin sensitization,

an allergic reaction, which becomes evident upon

re-exposure to this material.

Ingestion:

Harmful if swallowed. May cause gastrointestinal

irritation with nausea, vomiting and diarrhea. May

cause corrosion and permanent tissue destruction

of the esophagus and digestive tract. May cause

headache.

Inhalation:

May cause respiratory tract irritation. Material has a

low vapor pressure, so exposure to vapor is not

likely.

Chronic:

Prolonged or repeated skin contact may cause

dermatitis. May cause kidney injury. Prolonged or

repeated exposure may cause yellow staining of

the skin and conjunctiva and "yellow vision".

Section 4 - FIRST AID MEASURES

Eyes: Immediately flush eyes with plenty of water

for at least 15 minutes, occasionally lifting the

upper and lower eyelids. Get medical aid

immediately.

Skin:

Get medical aid immediately. Flush skin with plenty

of water for at least 15 minutes while removing

contaminated clothing and shoes.

Wash clothing before reuse.

Ingestion:

If victim is conscious and alert, give 2-4 cupfuls of

milk or water.

Never give anything by mouth to an unconscious

person. Get medical aid immediately.

Inhalation:

Remove from exposure and move to fresh air

immediately. If not breathing, give artificial

respiration. If breathing is difficult, give oxygen. Get

medical aid.

Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES

General Information:

Evacuate area and fight fire from a safe distance.

As in any fire, wear a self-contained breathing

apparatus in pressure-demand, MSHA/NIOSH

(approved or equivalent), and full protective gear.

Exposure to heat may promote violent

decomposition. This material is an explosion hazard

when exposed to heat, mechanical shock, or

friction. This material poses an explosion hazard

when dry. Approach fire from upwind to avoid

hazardous vapors and toxic decomposition

products.

Extinguishing Media:

Do NOT use carbon dioxide. Do NOT use

halogenated agents. Use flooding quantities of

water as spray. Cool containers with flooding

quantities of water until well after fire is out.

Section 6 - ACCIDENTAL RELEASE MEASURES

General Information: Use proper personal protective

equipment as indicated in Section 8.

Spills/Leaks:

Remove all sources of ignition. If the material is dry,

explosives experts may be necessary to dispose of

the spill. Isolate area and deny entry. Provide

ventilation. Evacuate unnecessary personnel.

Section 7 - HANDLING and STORAGE

Handling:

Wash thoroughly after handling. Use with adequate

ventilation.

Minimize dust generation and accumulation.

Material is heat, shock and/or friction sensitive. Use

care in handling and storage. Loosen closure

cautiously before opening. Avoid breathing dust,

vapor, mist, or gas. Avoid contact with eyes, skin,

and clothing. Keep away from heat, sparks and

flame. Container should be opened by a technically

qualified person. Avoid mechanical shock and

friction.

Dried crystals may be present within threads of

screw top containers and present a detonation

hazard when opening. If a bottle of picric acid is old

and has a metal cap, care must be exercised as

highly shock sensitive metal picrates may have

formed.

Storage:

Keep away from heat, sparks, and flame. Keep

away from sources of ignition. Store in a tightly

closed container. Store in a cool, dry, well-

ventilated area away from incompatible

substances. Keep away from metals. Material can

explode if dry. Do not store on concrete.

Separate from organic materials.

Section 8 - EXPOSURE CONTROLS, PERSONAL

PROTECTION

Engineering Controls:

Use process enclosure, local exhaust ventilation, or

other engineering controls to control airborne levels

below recommended exposure limits. Facilities

storing or utilizing this material should be equipped

with an eyewash facility and a safety shower.

Personal Protective Equipment Eyes: Wear

appropriate protective eyeglasses or chemical

safety goggles as described by OSHA's eye and

face protection regulations in 29 CFR 1910.133 or

European Standard EN166.

Skin:

Wear appropriate protective gloves to prevent skin

exposure.

Clothing:

Wear appropriate protective clothing to prevent

skin exposure.

Respirators:

Follow the OSHA respirator regulations found in 29

CFR 1910.134 or European Standard EN 149.

Always use a NIOSH or European Standard EN 149

approved respirator when necessary.

Section 9 - PHYSICAL AND CHEMICAL

PROPERTIES

Physical State: Solid

Color: Not available.

Odor: Not available.

pH: Not available.

Vapor Pressure: Not available.

Viscosity: Not available.

Boiling Point: Not available.

Freezing/Melting Point: 121.00 - 123.00 deg C

Autoignition Temperature: Not applicable.

Flash Point: Not applicable.

Explosion Limits, lower: Not available.

Explosion Limits, upper: Not available.

Decomposition Temperature:

Solubility in water:

Specific Gravity/Density: 1.7630g/cm3

Molecular Formula: C6H3N3O7

Molecular Weight: 229.11

Section 10 - STABILITY AND REACTIVITY

Chemical Stability:

Explodes above 572F (300C) with release of oxides

of nitrogen.

Conditions to Avoid:

High temperatures, mechanical shock, ignition

sources.

Incompatibilities with Other Materials:

Metals, reducing agents, bases, amines, ammonia,

concrete (forms friction sensitive calcium picrate).

Hazardous Decomposition Products:

Carbon monoxide, oxides of nitrogen, carbon

dioxide.

Hazardous Polymerization: Will not occur.

Section 11 - TOXICOLOGICAL INFORMATION

RTECS#:

CAS# 88-89-1: TJ7875000 LD50/LC50:

CAS# 88-89-1: Oral, rat: LD50 = 200 mg/kg.

Carcinogenicity:

Phenol, 2,4,6-Trinitro- - Not listed by ACGIH, IARC,

or NTP.

Other:

See actual entry in RTECS for complete information.

Section 12 - ECOLOGICAL INFORMATION

Ecotoxicity:

Rainbow trout (Salmo gairdneri), LC50=109.6

mg/L/96 hr; American oysters (Crassotrea virginica),

LC50=254.9 mg/L/14 hr; Bluegill (Lepomis

macrachirus), LC50=193 mg/L/24 hr

Section 13 - DISPOSAL CONSIDERATIONS

Dispose of in a manner consistent with federal,

state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA

Shipping Name: Trinitrophenol

Hazard Class: 1.1

UN Number: 0154

Packing Group: II

IMO


Hazard Class: 1.1

UN Number: 0154

Packing Group: II

RID/ADR


Hazard Class: 1.1

UN Number: 0154

Packing group: II

Section 15 - REGULATORY INFORMATION

European/International Regulations

European Labeling in Accordance with EC Directives

Hazard Symbols: T E

Risk Phrases:

R 2 Risk of explosion by shock, friction, fire or

other sources of ignition.

R 23/24/25 Toxic by inhalation, in contact with skin

and if swallowed.

R 4 Forms very sensitive explosive metallic

compounds.

R 43 May cause sensitization by skin contact.

Safety Phrases:

S 28 After contact with skin, wash immediately

with...

S 35 This material and its container must be

disposed of in a safe way.

S 37 Wear suitable gloves.

S 45 In case of accident or if you feel unwell, seek

medical advice immediately (show the label where

possible).

WGK (Water Danger/Protection)

CAS# 88-89-1: 2

United Kingdom Occupational Exposure Limits

CAS# 88-89-1: OES-United Kingdom, TWA 0.1

mg/m3 TWA

CAS# 88-89-1: OES-United Kingdom, STEL 0.3

mg/m3 STEL

United Kingdom Maximum Exposure Limits

Canada

CAS# 88-89-1 is listed on Canada's DSL List.

CAS# 88-89-1 is listed on Canada's Ingredient

Disclosure List.

Exposure Limits

CAS# 88-89-1: OEL-AUSTRALIA:TWA 0.1

mg/m3;STEL 0.3 mg/m3;Skin

OEL-BELGIUM:TWA 0.1 mg/m3;STEL 0.3

mg/m3;Skin

OEL-DENMARK:TWA 0.1 mg/m3;Skin

OEL-FINLAND:TWA 0.1 mg/m3;STEL 0.3 mg/m3;Skin

OEL-FRANCE:TWA 0.1 mg/m3;Skin

OEL-GERMANY:TWA 0.1 mg/m3;Skin

OEL-HUNGARY:TWA 0.1 mg/m3;STEL 0.2

mg/m3;Skin

OEL-THE NETHERLANDS:TWA 0.1 mg/m3;Skin

OEL-THE PHILIPPINES:TWA 0.1 mg/m3;Skin

OEL-POLAND:TWA 0.1 mg/m3

OEL-SWITZERLAND:TWA 0.1 mg/m3;STEL 0.2

mg/m3;Skin

OEL-TURKEY:TWA 0.1 mg/m3;Skin

OEL-UNITED KINGDOM:TWA 0.1 mg/m3;STEL 0.3

mg/m3;Skin

OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA

check ACGIH TLV

OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check

ACGI TLV

US FEDERAL

TSCA

CAS# 88-89-1 is listed on the TSCA inventory.