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M. Phar (Pharmacognosy) Revised Syllabus Applicable w.e.f. Academic Session 2011-12 (22022012) Page 1 of 16
Study & Evaluation Scheme
of
Master of Pharmacy
(Pharmacognosy) [Applicable w.e.f. Academic Session 2011-12 till revised]
TEERTHANKER MAHAVEER UNIVERSITY N.H.-24, Delhi Road, Moradabad, Uttar Pradesh-244001
Website: www.tmu.ac.in
M. Phar (Pharmacognosy) Revised Syllabus Applicable w.e.f. Academic Session 2011-12 (22022012) Page 2 of 16
To qualify the course a student is required to secure a minimum of 40% marks in aggregate in the end
semester examination and teachers continuous evaluation (i.e. both internal and external). A candidate who
secures less than 40% of marks in a course shall be deemed to have failed in that course. The student should
have overall 50% marks in a semester to clear the semester. In case a student has more than 40% in each
course but less than 50% overall in a semester he/she shall re-appear in one or two course(s) to improve the
percentage. There will be three Class Tests in a semester and an average of the marks obtained in best two
tests will be computed (cumulatively) for the final result.
The class tests would comprise of five questions. Student shall have to answer three questions out of which one question will be compulsory. Each question would be of five marks.
Question Paper Structure:
1. The question paper shall consist of eight questions. Out of which first question shall be of short
answer type (not exceeding 50 words) and will be compulsory. Question No. 1 shall contain 8 parts
representing all units of the syllabus and students shall have to answer any five (weightage 4 marks
each).
2. Out of the remaining seven questions, a student shall be required to attempt any five questions.
There will be minimum one and maximum two questions from each unit of the syllabus. The
weightage of Question No. 2 to 8 shall be 10 marks each.
M. Phar (Pharmacognosy) Revised Syllabus Applicable w.e.f. Academic Session 2011-12 (22022012) Page 3 of 16
4. Ardrey, R.E., Pharmaceutical Mass Spectra, Pharmaceutical Press, London.
5. Sethi, P.D., Quantitative Analysis of Pharmaceutical Formulations, CBS Publishers, New Delhi.
6. Kalsi, P.S., Spectroscopy of Organic Compounds, new age publishers, New Delhi.
7. Gross J.H., Mass Spectrometry, Springer Berlin, Heidelberg.
8. Haffmann D. H. Advances in Chromatography, Marcel Dekker.
9. Braun Robert D., Introduction to Instrumental Analysis, McGraw-Hill.
10. Wilfried, M.A. Niessen, Liquid Chromatography-Mass Spectrometry, Marcel Dekker.
*Latest editions of all the suggested books are recommended.
M. Phar (Pharmacognosy) Revised Syllabus Applicable w.e.f. Academic Session 2011-12 (22022012) Page 5 of 16
Semester-I
EVALUATION OF DRUGS
Course Code: MPG101 L-4, T-2, P-0, C-5
Objective: The basic objective of this course is to get familiar with evaluation of drugs.
Unit – 1
Evaluation of Drugs: Concept, considerations, parameters and methods of quality control for
medicinal plant materials as per various pharmacopoeia and other guidelines.
Only interpretation of data UV, IR, NMR, 1H NMR, 13C NMR & Mass spectroscopy for purification and structural elucidation of phytoconstituents. Herbal fingerprint profile of single and
multicomponent herbal drugs. Stability testing of natural products.
(8 Hours)
Unit - 2 Standardization of Ayurvedic Formulations and single crude drug with references to: Identity,
purity and quality of crude drugs. Determination of pesticide residues, determination of arsenic and heavy metals, determination of microorganisms, determination of microbial load in crude drugs.
Identification of aflatoxins in crude drugs. Quality assurance in herbal drug industry. (8 Hours)
Unit – 3
A. Quantitative microscopy, including lycopodium spore method as applied to drug evaluation and
pollen grain analysis. Principles and procedures of microtomy and advanced histological techniques
as applied to Pharmacognosy.
B. Principle and procedure involved in biological test of the following: i. Mycobacterium tuberculosis
ii. Living contaminants in vaccines
iii. Determination of toxic elements (8 Hours)
Unit – 4
Study of pharmacological screening methods of the following categories of drugs: Anti-inflammatory, hypolipidemic, diuretics, cardiovascular, hepatoprotectives, anticancer, antidiabetics,
antiulceratives, antioxidants, immunomodulators, antimalarial, antimicrobial, antiallergic and antifertility. (8 Hours)
Unit - 5
Regulatory requirements for new drugs: Markers constituents: Definition, importance in crude drug standardization. Examples of Biomarkers. Standardization, quality, efficacy and safety
requirements. (8 Hours)
Books Recommended:
1. Vogel G. H., Drug Discovery and Evaluation, Springer.
2. Dhawan, B.N., Shrimal, R.C., Use of Pharmalogical Techniques for the Evaluation of Natural
Products, CDRI, Lucknow.
3. Pulok K. Mukherjee, Quality Control of Herbal drugs. An Approach to Evaluation of
Botanicals, Business Horizons.
4. V. Rajpal, Standardization of Botanicals, Vol. I & II, Eastern Publishers, New Delhi.
5. WHO Quality Control Methods of Medicinal Plant Materials, WHO.
6. Indian Herbal Pharmacopoeia, Vol. 1 & 2.
7. Wallis, T.E., Practical Pharmacognosy, Churchill. 8. Wagner’s, Plant Drug Analysis, A Thin layer Chromatography, Atlas.
9. Bogers, Medicinal and Aromatic plants, Agricultural, Commercial, Ecological, Legal,
Pharmacological and Social Aspects. Springer.
M. Phar (Pharmacognosy) Revised Syllabus Applicable w.e.f. Academic Session 2011-12 (22022012) Page 6 of 16
* Latest editions of all the suggested books are recommended.
Semester- I
ADVANCES IN PHARMACOGNOSY
Course Code: MPG102 L-4, T-2, P-0, C-5
Objective: The basic objective of this course is to get familiar with advances in the pharmacognosy.
Unit - 1
Recent development in the quality control of herbal drugs and regulatory requirements for herbal
industry including G.M.P. & G.L.Ps. (8 Hours)
Unit - 2
Plant growth regulators and their use, scope and limitations in Pharmacognosy, Effect of growth
hormones on production of secondary plant metabolites. (8 Hours)
Unit - 3
Nutraceuticals: A biochemical background of use of herbal products, anthocyanins,
proanthocyanidins, flavanones and resveratrol. (8 Hours)
Unit --4
Antibacterial, antiviral, hypolipidemic, anti-inflammatory, anti-malarial, hepatoprotective, antidiabetics and anticancer drugs from natural origin, Biological allergens and hallucinogens.
(8 Hours)
Unit - 5 Marine Pharmacognosy: Definition, present status, classification of important bioactive agents, their
general methods of isolation and purification (where reported), study of important bioactive agents
3. Rajdan, M., Introduction to Plant Tissue Culture, Oxford IBH Publishing Co. Pvt. Ltd., New
Delhi. 4. Martin Dean F, Gorge Padilla, Marine Pharmacognosy, R R Bowker Publishing.
5. Pharmacognosy and Phytochemistry, Mohammad Ali, CBS Publishers & Distribution, New
Delhi.
6. Kalia, A.N., Text Book of Industrial Pharmacognosy. Satish Kumar Jain for CBS.
7. Vyas, S.P., Dixit, V.K., Pharmaceutical Biotechnology. CBS Publishers.
8. Tyler, Brady and Robbers, Pharmacognosy, Lea & Febiger, 1981.
9. Prof. S. H. Ansari, Essentials of Pharmacogosy, Birla Publishers, Rohtas Nagar, Delhi.
10. PDR for Nutritional Supplements, Medical Economics Co., 2001
* Latest editions of all the suggested books are recommended.
M. Phar (Pharmacognosy) Revised Syllabus Applicable w.e.f. Academic Session 2011-12 (22022012) Page 7 of 16
Semester- I
MODERN ANALYTICAL TECHNIQUE (MAT) LAB
Course Code: MPA151 L-0, T-0, P-8, C-4
Objective: The basic objective of this course is to get familiar with different analytical instruments.
Based on the Course Code: MPA101
M. Phar (Pharmacognosy) Revised Syllabus Applicable w.e.f. Academic Session 2011-12 (22022012) Page 8 of 16
Semester I
EVALUATION OF DRUGS LAB
Course Code: MPG152 L-0, T-0, P-8, C-4
Objective: The basic objective of this course is to get familiar with practicals of evaluation of drugs.
Based on the Course Code: MPG102
M. Phar (Pharmacognosy) Revised Syllabus Applicable w.e.f. Academic Session 2011-12 (22022012) Page 9 of 16
Semester II
RECENT DEVELOPMENTS IN PHARMACOGNOSY
Course Code: MPG201 L-4, T-2, P-0, C-5
Objective: The basic objective of this course is to get familiar with recent developments in
pharmacognosy.
Unit - 1
Ethnopharmacognosy / Ethnomedicine, its concept, scope and importance. (8 Hours)
Unit - 2
Aromatic plant resources in India. Screening: Phyto-chemical and Biological screening procedures of
vegetable drugs of medicinal importance. (8 Hours)
Unit - 3
Plant tissue culture techniques & its application in relation to phytopharmaceuticals: Techniques of
initiation & maintenance of various types of cultures, Immobilized cell techniques, Hairy Root
Culture, Germ plasma storage, biotransformation studies, recent advances in elicitor techniques and
production of biological active constituents in static, suspension, multiple shoot cultures. (8 Hours)
Unit - 4
Bioreactors for production of biologically active constituents and other applications of plant tissue culture techniques. Biosynthetic potential of tissue cultures and factors affecting production of
secondary metabolites by tissue culture techniques. (8 Hours)
Unit - 5
History of chemotaxonomy development chemotaxonomy of higher and lower plants with special reference to chemotaxonomic importance of alkaloids, flavonoids and glycosides. (8 Hours)
Objective: The basic objective of this course is to get familiar with the method, instrumentation and
the technology of the topic that is selected for the dissertation.
Curriculum Details:
1. The course will comprise of preparation of synopsis for the proposed research work to be
done during third and fourth semester courses.
2. The allotted supervisor will provide guidelines and determine the topic of the research work
based on thorough literature reviews.
3. The final presentation will be evaluated by the supervisor(s) concerned for 25 marks.
4. A committee of senior faculty of the institute including supervisor(s), will finally evaluates
the quality of the proposed work and its relevance in the pharmaceutical field (out of 75
marks).
M. Phar (Pharmacognosy) Revised Syllabus Applicable w.e.f. Academic Session 2011-12 (22022012) Page 13 of 16
Semester II
INDUSTRIAL IMPORTANCE OF PHARMACOGNOSY LAB
Course Code: MPG252 L-0, T-0, P-8, C-4
Objective: The basic objective of this course is to get familiar with industrial pharmacognosy
practicals.
Based on the Course Code: MPG202
M. Phar (Pharmacognosy) Revised Syllabus Applicable w.e.f. Academic Session 2011-12 (22022012) Page 14 of 16
Semester II
PHYTOPHARMACEUTICALS LAB
Course Code: MPG253 L- 0, T-0, P-8, C-4
Objective: The basic objective of this course is to get familiar with Phytopharmaceuticals practicals.
Based on the Course Code: MPG203
M. Phar (Pharmacognosy) Revised Syllabus Applicable w.e.f. Academic Session 2011-12 (22022012) Page 15 of 16
Semester III
RESEARCH PROJECT (PHASE-I)
(TO BE CONTINUED IN SEMESTER-IV) Course Code: MPG351 L- 0, T-0, P-48, C-24
Objective: The basic objective of this course is to represent the findings of the project that has been
done in the dissertation.
Guidelines:
1. The course will comprise of the confirmation of the proposed research work based on the
initial experimentation to confirm the feasibility of the work.
2. The allotted supervisor(s) will provide guidelines with exploration of the line of action with
recent trends of research in the related field and confirm global acceptability with regards to
industry and academic problems.
3. The continuous literature survey and modification of experimental pathway will be taken in
to practice with regular monitoring. 4. The candidate’s performance will be evaluated by the supervisor(s) and the internal
committee of at least three senior faculties in addition to the allotted supervisor(s). There will be atleast two seminars to be presented before the committee in this semester consisting of
the progress of the research work. 5. Each seminar will be of 50 marks.
M. Phar (Pharmacognosy) Revised Syllabus Applicable w.e.f. Academic Session 2011-12 (22022012) Page 16 of 16