Martina Vasakova Emilia Kopecka Jitka Soukupova Thomayer University Hospital Prague Tuberculosis in the Czech Republic. MDR- TB Unit of the Czech Republic.

Martina VasakovaEmilia KopeckaJitka Soukupova

Thomayer University Hospital Prague

Tuberculosis in the Czech Republic.MDR- TB Unit of the Czech Republic in

Thomayer University Hospital

Tuberculosis in the Czech RepublicCzech Republic belongs to low incidence countriesGood policy against TB spread from the beginning

of 20th century-Masaryk´s league against TBAfter the 2nd World War active policy against

tuberculosis enhanced by development of new drugs against M. tuberculosis

Active screening for new cases of tuberculosis- chest X-rays, investigation of contacts

From 2000 starts active screening for LTBI- begins in healthcare workers- Thomayer University Hospital and Faculty Hospital Bulovka

Experience in TB eradication, state pollicy against TB spread

TB incidence in some European states- The countries adjoining European Union after 2004

0

20

40

60

80

100

120

140

160

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006

TB cases / 100,000

Romania

Lithuania

Latvia

Bulgaria

Estonia

Poland

Hungary

Slovakia

Slovenia

Czech Rep

Malta

Cyprus

*

Thomayer University HospitalModern developing hospital offering highly

specialized health care50.000 patients a year- one of the largest

health institutions in the Czech RepublicFounded in 1954 Fully equipped hospital with major surgical

and internal departments1984, after 30 years of its existence

accepted amongst the University hospitals

Thomayer University HospitalProvides care mainly to patients from PragueUrgent and special cases from the whole of

central Bohemia- heliport33 focused departments covering all current

medical areasAccent on traumatology (especially in children),

oncology, respiratory diseases and pediatric care Holder of the international certificate BABY

FRIENDLY HOSPITALUniversity hospital – education of young

physicians and nurses

Department of Respiratory Diseases Respiratory care for patients from part of Prague and Central Bohemia,

but in special cases for the whole Czech Republic Allergology and Clinial Immunology specialised care and consulting for

the whole Czech Republic Teaching base of the 1st Medical School of Charles University and

Thomayer University Hospital One of the largest departments of the Thomayer University Hospital 80 beds for acute cases including 5-beds ICU 35 beds for long-term treatment of tuberculosis patients including

multidrug-resistant one supplied with modern equipment enabling proper and quick diagnosis

and treatment of large spectrum of pulmonary diseases. ambulant care in specialized outpatient ambulances - chronic

obstructive lung disease (COPD), idiopathic pulmonary fibrosis and other interstitial lung diseases , with difficult-to-treat asthma, NTM

Center for alpha 1 antitrypsin deficiency for the Czech Republic Projects and grants- COPD, IPF, asthma, A1-AT deficiency, LTBI

MDR TB Unit Within the department for tuberculosis Multidrug-Resistant tuberculosis Unit recognised by

Ministry of Health from 2007 Serves for all MDR-TB patients diagnosed in the Czech

Republic- for Czechs, but also other nations, mainly immigrants

Development of the Microbiological department- widening the spectrum of molecular diagnostic methods for quick diagnosis of tuberculosis, including drug- susceptibility tests and quick diagnosis of drug resistance

Grants and projects- -TB-NET- pan-European project on MDR-TB- - Norway Funds- Prevention of TB spread in the Czech

Republic- TB of lungs and also urogenital system

MDR-TB in the Czech Republic

Number of MDR-TB patients in the years 2000-2009 (to the end of September 2009) in the Czech Republic- 67

33 foreign immigrants and 34 Czech inhabitants

MDR TB in the Czech Republic

Year MDR TB (No of persons)

No of persons with resistance to H,S,E,R

2000 23 12

2001 32 11

2002 23 8

2003 13 7

2004 19 11

2005 17 12

2006 18 14

2007 14 10

2008 12 6

MDR- TB in Thomayer University Hospital

Year MDR TB Total No of patients

NationalitiesCzech Former

USSRVietnam Poland Mongoli

a

2000 2 1 12001 16 15 12002 14 9 4 12003 9 3 3 2 12004 6 3 32005 3 2 12006 3 1 22007 7 4 32008 9 4 2 1 22009 7 1 2 1 3

What do we offer?

We offer the clinical base for investigation of tuberculosis including MDR-TB within the frames of multinational projects. We are well equipped not only for clinical care for the patients but also for the investigation including the basic research

Thank you for your kind attention