Stimulus Activators MAPKKK MAPKK MAPK ERK1 ERK2 JNK1 JNK2 JNK3 ERK5 BMK1 p38 MAPK Growth factors, Mitogens Stress, Cytokines, Growth factors Stress, Growth factors, Mitogens Raf Mos Tpl2 MEKK2 MEKK3 Tpl2 MLK3 TAK1 TAO1 DLK MEKK3 ASK1 Tpl2 Ras STE20 Rho TRAF2 TRAF3 Rac Rho Src Ras cdc42 TRAF6 MEK1 MEK2 MEK5 MKK3 MKK4 MKK4 MKK7 MKK6 TAO2 MEKK4 ZAK MEKK1 MLK1/2/3/4 TAO2 MEKK2 ASK1 TAK1 MEKK4 TAO1 DLK ZAK Effect Proliferation Differentiation Inflammation Apoptosis Proliferation Differentiation Metabolism Proliferation Differentiation MAPK pathway To find out more, please visit www.abcam.com Copyright © 2018 Abcam. All rights reserved