Male reproductive system

Male reproductive system

MALE REPRODUCTIVE SYSTEM

CLASSIFICATION

• TESTIS• GONADAL TRACT• ACCESSORY GLANDS• PENIS

FUNCTIONS

•GENERATIVE•ENDOCRINE

MALE REPRODUCTIVE SYSTEMTESTIS

Type of structure – parenchymal lobulated

Stroma – Connective tissue + smooth myocytes + elastic fibres - Capsule - tunica albuginea (DCT + serosa) - Mediastinum (DCT) - Interlobular septae (DCT) - Intralobular LCT with calillaries and intersticial (endocrine) cellsParenchyma – seminiferous tubules

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MALE REPRODUCTIVE SYSTEMPeculiarities of stroma in testis- T.albuginea is covered by serosa- includes SM and EF- in lobules fenestrated capillaries are located- Intersticial cell – endocrine – produce TESTOSTERON- endocrine function is under the hypothalamo-pituatary system control (LH)- interstitial (Leidig) cells form groups near capllaries, have round N and oxyphilic cytoplasm- EM: smooth ER, mitochondriae with tubulo-vesicular crysts, lipid droplets, crystalloid.

MALE REPRODUCTIVE SYSTEM

SEMINIFEROUS TULULES

1. Convoluted2. 1-4 tubules in one lobule3. Wall is lined by epitheliospermatogenic layer (ESL)4. ESL includes supporting (Sertolli) cells +

spermatogenic cells5. Surrounded by myoid cells.

MALE REPRODUCTIVE SYSTEM

Sertolly`s cells- Pyramidal shape- Processes are joined by tight junctions and

subdivide ESL into 2 poles- Poles: basal and adluminal- make microenvironment for prermatogenic cells - Participate in formation of blood-testis barrier

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MALE REPRODUCTIVE SYSTEM

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SPERMATOGENIC cells

- Spermatogonia- Primary spermatocytes- Secondary spermatocytes- Spermatides- Spermatozoa

MALE REPRODUCTIVE SYSTEM

SPERMATOGENESIS includes:

1. Proliferation (mitosis)2. Growth (prophase of 1st meiotic division)3. Maturation (1st and 2nd meiotic division)4. Formation (differentiation – spermiogenesis)

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MALE REPRODUCTIVE SYSTEM

Spermiogenesis includes changes of:

1. Shape2. Size of Nucleus3. Number of mitochondriae4. Location of Golgi apparatus3. Acrosome formation4. Microtubules arrangement with tail formation

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БА

MALE REPRODUCTIVE SYSTEM

Blood testis barrier

1. Capallaries wall (Ec+BM)2. Perivascular LCT + Mph3. Myoid cells (+BM)4. Sertolli`s cells + BM and TJ

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Regulation of testis

Гипоталамус

Тестостерон

ЛГ

ФСГ

Клетки Лейдига

Семявыносящие пути

Тестостерон

Гипофиз

АСБ

Суспендоцит

DIAGNOSTICS

MALE REPRODUCTIVE SYSTEM

MALE REPRODUCTIVE SYSTEM

Gonadal tract

1. Intragonadal 2. Extragonadal

MALE REPRODUCTIVE SYSTEM

Epidydimis:

1. Head2. Body3. Tail

Two types of tubuled- Ductuli efferentis- Ductus epidydimis

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Type of structure – hollow with layerel wall

Layers:

1. Mucosa (Ep + Lamica propria)2. Muscularis (Smooth muscles)3. Adventitia.

Seminal vesicles

Accessory glands

Prostate

Accessory glands

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