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Macromolecules Structure & Function
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Macromolecules Structure & Function. You Are What You Eat Total%Daily Value Calories1280 Total Fat (g)5991 Saturated Fat (g)1679 Cholesterol (mg)8528.

Dec 26, 2015

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Ronald Goodwin
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Page 1: Macromolecules Structure & Function. You Are What You Eat Total%Daily Value Calories1280 Total Fat (g)5991 Saturated Fat (g)1679 Cholesterol (mg)8528.

Macromolecules

Structure & Function

Page 2: Macromolecules Structure & Function. You Are What You Eat Total%Daily Value Calories1280 Total Fat (g)5991 Saturated Fat (g)1679 Cholesterol (mg)8528.

You Are What You EatTotal %Daily

Value

Calories 1280

Total Fat (g) 59 91

Saturated Fat (g) 16 79

Cholesterol (mg) 85 28

Sodium (mg) 1420 59

Carbohydrates (g) 158 53

Dietary Fiber (g) 11 42

Protein (g) 33 -

Big Mac Meal

http://www.mcdonalds.com/app_controller.nutrition.mcmeal.bagmeal.html

Page 3: Macromolecules Structure & Function. You Are What You Eat Total%Daily Value Calories1280 Total Fat (g)5991 Saturated Fat (g)1679 Cholesterol (mg)8528.

Carbohydrates C : 2H : O

carbo hydrate (water)

Examples Glucose C6H12O6

Fructose C6H12O6

Isomers

Monosaccharides (one sugar) Fuel Sweet!

Page 4: Macromolecules Structure & Function. You Are What You Eat Total%Daily Value Calories1280 Total Fat (g)5991 Saturated Fat (g)1679 Cholesterol (mg)8528.

Carbohydrates Disaccharides (two

sugars)

Examples Sucrose Dehydration synthesis

Coca-Cola Classic®

Carbonated water, high fructose corn syrup and/or sucrose, caramel color, phosphoric acid, natural flavors (vegetable source), caffeine.

Page 5: Macromolecules Structure & Function. You Are What You Eat Total%Daily Value Calories1280 Total Fat (g)5991 Saturated Fat (g)1679 Cholesterol (mg)8528.

Carbohydrates Polysaccharides

(many sugars) Up to thousands of

units Fuel Storage

Starch- Plants Glycogen- Animals

Starch & Glycogen

Page 6: Macromolecules Structure & Function. You Are What You Eat Total%Daily Value Calories1280 Total Fat (g)5991 Saturated Fat (g)1679 Cholesterol (mg)8528.

Carbohydrates Polysaccharides

(many sugars) Up to thousands of

units Structural

Cellulose Hard to digest!

Total %DailyValue

Calories 1280

Carbohydrates (g) 158 53

Dietary Fiber (g) 11 42

Starch & Glycogen

Page 7: Macromolecules Structure & Function. You Are What You Eat Total%Daily Value Calories1280 Total Fat (g)5991 Saturated Fat (g)1679 Cholesterol (mg)8528.

Carbohydrates Polysaccharides

(many sugars) Up to thousands of

units Structural

Starch & Glycogen

Cellulose

Chitin

Page 8: Macromolecules Structure & Function. You Are What You Eat Total%Daily Value Calories1280 Total Fat (g)5991 Saturated Fat (g)1679 Cholesterol (mg)8528.

monosaccharide

disaccharide

polysaccharide

Carbohydrate Structures

Page 9: Macromolecules Structure & Function. You Are What You Eat Total%Daily Value Calories1280 Total Fat (g)5991 Saturated Fat (g)1679 Cholesterol (mg)8528.

Lipids Hydrophobic

Oil & water do not mix!

Less O

Total %DailyValue

Calories 1280

Total Fat (g) 59 91

Saturated Fat (g) 16 79

Cholesterol (mg) 85 28

Sodium (mg) 1420 59

Carbohydrates (g) 158 53

Dietary Fiber (g) 11 42

Protein (g) 33 -

Examples Fatty acid Triglyceride Saturated Unsaturated

Page 10: Macromolecules Structure & Function. You Are What You Eat Total%Daily Value Calories1280 Total Fat (g)5991 Saturated Fat (g)1679 Cholesterol (mg)8528.

Lipids

Large French FriesPotatoes, partially hydrogenated soybean oil, natural flavor (beef source), dextrose, sodium acid pyrophosphate (to preserve natural color). Cooked in partially hydrogenated vegetable oils (may contain partially hydrogenated soybean oil and/or partially hydrogenated corn oil and/or partially hydrogenated canola oil and/or cottonseed oil and/or sunflower oil and/or corn oil).

Page 11: Macromolecules Structure & Function. You Are What You Eat Total%Daily Value Calories1280 Total Fat (g)5991 Saturated Fat (g)1679 Cholesterol (mg)8528.

Lipids Energy Storage!

1 g of carbohydrate 4 calories

1 g of fat 9 calories Fuel of choice for flying

insects Insulation Waterproofing Membrane

Phospholipid Steroids

Cholesterol Hormones

Page 12: Macromolecules Structure & Function. You Are What You Eat Total%Daily Value Calories1280 Total Fat (g)5991 Saturated Fat (g)1679 Cholesterol (mg)8528.

Fatty acid

Triglyceride

Phospholipid

Steroid

Page 13: Macromolecules Structure & Function. You Are What You Eat Total%Daily Value Calories1280 Total Fat (g)5991 Saturated Fat (g)1679 Cholesterol (mg)8528.

Fatty acid

Page 14: Macromolecules Structure & Function. You Are What You Eat Total%Daily Value Calories1280 Total Fat (g)5991 Saturated Fat (g)1679 Cholesterol (mg)8528.

Proteins Workers of the cell

Responsible for most of what cells do

Diverse! Amino acids

Building blocks Dehydration synthesis Polypeptide

Total %DailyValue

Calories 1280

Total Fat (g) 59 91

Saturated Fat (g) 16 79

Cholesterol (mg) 85 28

Sodium (mg) 1420 59

Carbohydrates (g) 158 53

Dietary Fiber (g) 11 42

Protein (g) 33 -

Page 15: Macromolecules Structure & Function. You Are What You Eat Total%Daily Value Calories1280 Total Fat (g)5991 Saturated Fat (g)1679 Cholesterol (mg)8528.
Page 16: Macromolecules Structure & Function. You Are What You Eat Total%Daily Value Calories1280 Total Fat (g)5991 Saturated Fat (g)1679 Cholesterol (mg)8528.

Protein Structure Primary- amino acid sequence Secondary

Regular folding helix pleated sheet

Hydrogen bonding between O----+H-N on the polypeptide backbone

Tertiary Folding Interactions between the side groups

Page 17: Macromolecules Structure & Function. You Are What You Eat Total%Daily Value Calories1280 Total Fat (g)5991 Saturated Fat (g)1679 Cholesterol (mg)8528.

Tertiary Structure

Hydrogen bonds

Hydrophobic interaction

Disulfidebridge

Ionicbonds

Page 18: Macromolecules Structure & Function. You Are What You Eat Total%Daily Value Calories1280 Total Fat (g)5991 Saturated Fat (g)1679 Cholesterol (mg)8528.

Protein Structure Quaternary

More than one polypeptide More than one gene!

Page 19: Macromolecules Structure & Function. You Are What You Eat Total%Daily Value Calories1280 Total Fat (g)5991 Saturated Fat (g)1679 Cholesterol (mg)8528.

Protein Function Structural support

Collagen, silk, keratin

Page 20: Macromolecules Structure & Function. You Are What You Eat Total%Daily Value Calories1280 Total Fat (g)5991 Saturated Fat (g)1679 Cholesterol (mg)8528.

Transport

Page 21: Macromolecules Structure & Function. You Are What You Eat Total%Daily Value Calories1280 Total Fat (g)5991 Saturated Fat (g)1679 Cholesterol (mg)8528.

Hormones

Insulin

Page 22: Macromolecules Structure & Function. You Are What You Eat Total%Daily Value Calories1280 Total Fat (g)5991 Saturated Fat (g)1679 Cholesterol (mg)8528.

Receptors

Page 23: Macromolecules Structure & Function. You Are What You Eat Total%Daily Value Calories1280 Total Fat (g)5991 Saturated Fat (g)1679 Cholesterol (mg)8528.

Defense

Antibody

Page 24: Macromolecules Structure & Function. You Are What You Eat Total%Daily Value Calories1280 Total Fat (g)5991 Saturated Fat (g)1679 Cholesterol (mg)8528.

Enzymes A protein that does a special job

Thousands in the body

Catalyze reactions

Reusable

http://www.ncbi.nlm.nih.gov/Structure/mmdb/mmdbsrv.cgi?form=6&db=t&Dopt=s&uid=24928

Page 25: Macromolecules Structure & Function. You Are What You Eat Total%Daily Value Calories1280 Total Fat (g)5991 Saturated Fat (g)1679 Cholesterol (mg)8528.

ATPase

Page 26: Macromolecules Structure & Function. You Are What You Eat Total%Daily Value Calories1280 Total Fat (g)5991 Saturated Fat (g)1679 Cholesterol (mg)8528.

Nucleic Acid DNA & RNA (mRNA, tRNA, rRNA, & more)

Store information for making protein

Genes – sequence that codes for a protein

Four nucleotide bases: Adenine, Thymine, Guanine, Cytosine

Page 27: Macromolecules Structure & Function. You Are What You Eat Total%Daily Value Calories1280 Total Fat (g)5991 Saturated Fat (g)1679 Cholesterol (mg)8528.

Nucleotide

Sugar

Phosphate

Nitrogen Base

Page 28: Macromolecules Structure & Function. You Are What You Eat Total%Daily Value Calories1280 Total Fat (g)5991 Saturated Fat (g)1679 Cholesterol (mg)8528.

PolynucleotideHydrogen Bonds

Page 29: Macromolecules Structure & Function. You Are What You Eat Total%Daily Value Calories1280 Total Fat (g)5991 Saturated Fat (g)1679 Cholesterol (mg)8528.