Liver carbohydrate metabolism lipid metabolism protein & AA metabolism synthesis of plasma proteins vitamin metabolism digestion (bile synthesis) detoxification.

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Liver• carbohydrate metabolism• lipid metabolism• protein & AA metabolism• synthesis of plasma proteins• vitamin metabolism• digestion (bile synthesis)• detoxification

Pancreas• endocrine (insulin & glucagon)• exocrine (bicarb & digestive enzymes)

Right lobeLeft lobe

Coronary ligament

Falciform ligament

Ligamentum teres

Left lobe

Right lobe

Quadrate lobe

IVC

Hepatic portal vein

Portal triad• hepatic portal vein• hepatic artery• bile duct

Hepatic triad• hepatic portal vein• hepatic artery• bile ductule

Central vein

Hepatic lobule

sinusoids hepatocytes Bile canaliculus

Hepatic portal vein - Central vein – hepatic veins – inferior vena cava

Stomach & intestines

sup. & inf mesenteric veins

Hepatic portal vein

Liver sinusoids

Hepatic vein

Inferior vena cava

Hepatic portal system – 70% of blood to liver

Cirrhosis – portal hypertension, jaundice

Celiac trunk

Common hepatic artery

Arterial supply to liver – 30% of blood to liver

Cirrhosis of the liver• due to liver disease• scarring of liver tissue• jaundice (bile pigments)• ascites (fluid in abd cavity)• portal hypertension• causes:

• drug abuse• alcoholism• hepatitis C

normal

cholelithiasis

• Majority of gallstones are cholesterol, some from pigmented blood products

• Can see them on ultrasound

• Can use medications or surgery

tail

body

head

Pancreatic duct

Bile duct

Hepatopancreatic ampulla

QUESTIONS?

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