LIMBIC SYSTEM NBIO 401 Friday, December 3, 2010 Robinson.

LIMBIC SYSTEMNBIO 401

Friday, December 3, 2010Robinson

1)Hypothalamus

2)Amygdala

3)Hippocampus

4)Cingulate cortex

5)Nucleus accumbens

6)Septal nuclei

1)Hypothalamus

2)Amygdala

3)Hippocampus

4)Cingulate cortex

5)Nucleus accumbens

6)Septal nuclei

HYPOTHALAMUS

F igu re 3

anterior posterior

Location of the m edial forebrain bundle in asagittal section of a rat brain.

Hypothalamus

Inputs: -amygdala (via stria terminalis & direct) -hippocampus (via fornix) -septal nuclei (via medial forebrain bundle) -brainstem & spinal cord (via medial forebrain bundle)

Hypothalamus

Outputs: -amygdala (via stria terminalis) -hippocampus (via fornix) -septal nuclei (via medial forebrain bundle) -brainstem & spinal cord sympathetic and parasympathetic preganglionic neurons -pituitary (neural & humoral) -anterior thalamus (to prefrontal, orbital, & cingulate cortex)

INFUNDIBULUM(stalk of pituitary)

OPTICCHIASM

1)Hypothalamus

2)Amygdala

3)Hippocampus

4)Cingulate cortex

5)Nucleus accumbens

6)Septal nuclei

Amygdala

Inputs: -cortex (orbital, cingulate, entorhinal, & temporal) -hypothalamus (via stria terminalis & directly) -hippocampus -brainstem -septal nuclei -thalamus

Amygdala

Outputs: -cortex (orbital, cingulate, entorhinal, & temporal) -hypothalamus (via stria terminalis & directly) -hippocampus -septal nuclei -thalamus

1)Hypothalamus

2)Amygdala

3)Hippocampus

4)Cingulate cortex

5)Nucleus accumbens

6)Septal nuclei

Hippocampus

Inputs: -entorhinal cortex (receives input from cingulate, orbital, & prefrontal cortex) -amygdala (via fornix) -hypothalamus (via fornix)

Hippocampus

Outputs: -entorhinal cortex (receives input from cingulate, orbital, & prefrontal cortex) -anterior thalamus (to prefrontal, orbital, & cingulate cortex) -amygdala (via fornix) -hypothalamus (via fornix)

1)Hypothalamus

2)Amygdala

3)Hippocampus

4)Cingulate cortex

5)Nucleus accumbens

6)Septal nuclei

Cingulate cortex

Inputs:

-VP (somatosensory) thalamus (pain)

-anterior thalamus (to orbital cortex)

-amygdala

Cingulate cortex

Outputs:

-entorhinal cortex

-amygdala

1)Hypothalamus

2)Amygdala

3)Hippocampus

4)Cingulate cortex

5)Nucleus accumbens

6)Septal nuclei

(tohippocampus)

Nucleus accumbens

Inputs:

-amygdala

Nucleus accumbens

Outputs:

-basal ganglia

1)Hypothalamus

2)Amygdala

3)Hippocampus

4)Cingulate cortex

5)Nucleus accumbens

6)Septal nuclei

Septal Nuclei

Inputs:

-hippocampus (via fornix)

-amygdala

-medial midbrain reticular formation

Septal Nuclei

Outputs:

-hippocampus (via fornix)

-hypothalamus (via stria terminalis)

-amygdala (via medial forebrain bundle)

Papez Circuit

FIG U R E 14

Ende