Hippocrates circa 400BC “Let food be your medicine and medicine be your food"
Hippocrates circa 400BC
“Let food be your medicine and medicine be your food"
You Are What You Eat
• bloatedness
• diarrhea
• regurgitation
• rashes/flushing
• bloatedness
• diarrhea
• regurgitation
• rashes/flushing
Food = Nutrition
• How your body looks, feels, functions depends largely on what you put in it.
• The body needs a bare minimum of the right food to function.
• 1000 - 1800kcal per day
“What is food to one man may be fierce poison to another”
Lucretius circa 75BC
Food Allergy• Immediate onset IgE-mediated, skin test positive, often self-diagnosed
• Delayed onset IgG-mediated, skin test negative, rarely self-diagnosed
also called: Food Intolerance - UK Food Sensitivity - US
IgE Response to Food• Generally rapid onset after ingestion
• Histamine production is rapid
• Classic ‘Allergic’ response
IgG Response to Food• Food proteins are recognised as “foreign” • Food specific IgG production and formation of antigen/antibody
complexes • Complexes are deposited in tissues and activate complement • Complement and macrophages stimulate Inflammation • Delayed reaction and may last for days
Common Food Intolerances
Cows Milk Cheese Nuts
Gluten Wheat Egg Soya Yeast
• Detect the presence of IgG antibodies to specific foods which may be implicated in food intolerance in symptomatic patients
• Provide a means to identify the foods most likely to cause a problem, provided the symptoms are food related
Food Intolerance Test (FIT)
• ELISA: Enzyme-Linked ImmunoSorbent Assay
• a few drops of blood
Food Intolerance Test (FIT)
Food Intolerance Test (FIT)
• More than 200 food antigens tested
• antibody count >30 • ranked according to
reactivity • interpretation by
physician and/or nutritionist
How does it affect us?
• First tissue of contact
• Persistent inflammation
• Malabsorption
Conditions related to Food IgG• Bloating • Migraines • Insomnia • Weight problems/Obesity • Anxiety • Skin problems • Itchy skin (eczema) • Irritable bowl syndrome • Sinusitis
• Abdominal pain • Allergic rhinitis • Palpitations • Persistent cough • Pre-menstrual
problems
• Flattening of the absorptive surface of the intestines (villi)
• Normal villi
On endoscopy...
Malabsorption• Autoimmune diseases • Headaches • Fatigue • Depression • Arthritis and joint pain/stiffness and swelling • Chronic Respiratory symptoms (wheezing or bronchitis) • Abdominal Pain • Bowel Problems (colitis, diarrhoea, constipation)
Malabsorption
DISEASE
GENETICS ENVIRONMENT
Thank you.