1 RedLANO e –Journal 2 0 1 2 www.redlano.org (Epub ahead of print) Ciencias básicas Duncan, C. G. et. al. A heterozygous IDH1R132H/WT mutation induces genome-wide alterations in DNA methylation. Geno- me Res. 2012 Dec;22(12):2339-55. Lu, C. et. al. IDH mutation impairs histone demethylation and results in a block to cell differentiation. Nature. 2012 Feb 15;483(7390):474-8. Sturm, D. et. al. Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma. Cancer Cell. 2012 Oct 16;22(4):425-37. Turcan, S. et. al. IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype. Nature. 2012 Feb 15;483(7390):479-83. Chen, J. et. al. A restricted cell population propagates glio- blastoma growth after chemotherapy. Nature. 2012 Aug 23;488(7412):522-6. Friedmann-Morvinski, D. et. al. Dedifferentiation of neurons and astrocytes by oncogenes can induce gliomas in mice. Science. 2012 Nov 23;338(6110):1080-4. Muller, F. L. et. al. Passenger deletions generate therapeutic vulnerabilities in cancer. Nature. 2012 Aug 16;488(7411):337- 42. LECTURAS RECOMENDADAS NEURO–ONCOLOGÍA 2012 Sasaki, M. et. al. IDH1(R132H) mutation increases murine hae- matopoietic progenitors and alters epigenetics. Nature. 2012 Aug 30;488(7413):656-9. Singh, D. et. al. Transforming fusions of FGFR and TACC genes in human glioblastoma. Science. 2012 Sep 7;337(6099):1231-5. Snuderl, M. et. al. Mosaic amplification of multiple receptor tyrosine kinase genes in glioblastoma. Cancer Cell. 2011 Dec 13;20(6):810-7. Vivanco, I. et. al. Differential sensitivity of glioma- versus lung cancer-specific EGFR mutations to EGFR kinase inhibitors. Cancer Discov. 2012 May;2(5):458-71. Koivunen, P. et. al. Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation. Nature. 2012 Feb 15;483(7390):484-8. Neuro-oncología pediátrica Jones, D. T. et. al. Dissecting the genomic complexi- ty underlying medulloblastoma. Nature. 2012 Aug 2;488(7409):100-5. Northcott, P. A. et. al. Subgroup-specific structural variation across 1,000 medulloblastoma genomes. Nature. 2012 Aug 2;488(7409):49-56.
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1
RedLANO e–Journal2 0 1 2 w w w . r e d l a n o . o r g( E p u b a h e a d o f p r i n t )
Ciencias básicas
Duncan, C. G. et. al. A heterozygous IDH1R132H/WT mutation
induces genome-wide alterations in DNA methylation. Geno-
me Res. 2012 Dec;22(12):2339-55.
Lu, C. et. al. IDH mutation impairs histone demethylation
and results in a block to cell differentiation. Nature. 2012 Feb
15;483(7390):474-8.
Sturm, D. et. al. Hotspot mutations in H3F3A and IDH1 define
distinct epigenetic and biological subgroups of glioblastoma.
Cancer Cell. 2012 Oct 16;22(4):425-37.
Turcan, S. et. al. IDH1 mutation is sufficient to establish the
glioma hypermethylator phenotype. Nature. 2012 Feb
15;483(7390):479-83.
Chen, J. et. al. A restricted cell population propagates glio-
blastoma growth after chemotherapy. Nature. 2012 Aug
23;488(7412):522-6.
Friedmann-Morvinski, D. et. al. Dedifferentiation of neurons
and astrocytes by oncogenes can induce gliomas in mice.
Science. 2012 Nov 23;338(6110):1080-4.
Muller, F. L. et. al. Passenger deletions generate therapeutic
vulnerabilities in cancer. Nature. 2012 Aug 16;488(7411):337-
42.
LECTURAS RECOMENDADAS NEURO–ONCOLOGÍA 2012
Sasaki, M. et. al. IDH1(R132H) mutation increases murine hae-
matopoietic progenitors and alters epigenetics. Nature. 2012
Aug 30;488(7413):656-9.
Singh, D. et. al. Transforming fusions of FGFR and TACC genes
in human glioblastoma. Science. 2012 Sep 7;337(6099):1231-5.
Snuderl, M. et. al. Mosaic amplification of multiple receptor
tyrosine kinase genes in glioblastoma. Cancer Cell. 2011 Dec
13;20(6):810-7.
Vivanco, I. et. al. Differential sensitivity of glioma- versus lung
cancer-specific EGFR mutations to EGFR kinase inhibitors.
Cancer Discov. 2012 May;2(5):458-71.
Koivunen, P. et. al. Transformation by the (R)-enantiomer of
2-hydroxyglutarate linked to EGLN activation. Nature. 2012
Feb 15;483(7390):484-8.
Neuro-oncología pediátrica
Jones, D. T. et. al. Dissecting the genomic complexi-
ty underlying medulloblastoma. Nature. 2012 Aug
2;488(7409):100-5.
Northcott, P. A. et. al. Subgroup-specific structural variation
across 1,000 medulloblastoma genomes. Nature. 2012 Aug