Laura Pilkington (CSG Administrator) - MCRN Clinical Studies ...

MCRN Clinical Studies Groups(CSGs)

Laura PilkingtonClinical Studies Group Administrator

The NIHR Medicines for Children Research Network is part of the National Institute for Health Research Clinical Research Network, and forms part of the UK Clinical Research Network. The Networks support and deliver high quality clinical research studies.

What are MCRN CSGs?

MCRN CSGs are panels of stakeholders relevant to medicines for children who have the general remit to:

- Provide expert advice to investigators, the pharmaceutical industry and to the MCRN Study Adoption Committee (SAC)

- Identify gaps within current research and develop studies to successfully address these gaps

12 MCRN CSGsAllergy, Infection & Immunity Dr Mike Sharland

Anaesthesia, Pain, Intensive Care & Cardiology Dr Robert Tasker

Diabetes, Endocrinology & Metabolic Medicine Prof David Dunger

Gastroenterology, Hepatology & Nutrition Dr Stephen Murphy

General Paediatrics Dr Colin Powell

Methodology Prof Peter Brocklehurst

Neonatal Dr Mark Turner

MCRN/BAPN Nephrology CSG Prof Moin Saleem

Neurosciences Dr Timothy Martland

Pharmacy & Pharmacology Prof Ian Wong

Respiratory & Cystic Fibrosis Dr Paul Seddon

MCRN/arc Paediatric Rheumatology Dr Michael Beresford

MCRN CSG Membership

Role of MCRN CSGsReactive Role Proactive Role

To provide advice to investigators for the development of research proposals and funding applications

To identify gaps in current research within specialty areas and determine research priorities

To provide advice to commercial companies through the MCRN Industry Liaison Team

To develop clinical trials or other well designed studies to address research gaps

To advise the MCRN Study Adoption Committee regarding the quality of studies submitted to run through the network

To participate in strategic decisions of the MCRN through representation on the MCRN Board

Reactive Role“Provision of advice to investigators and Commercial Companies”

**October 2008**

Proactive Role (1)“Identifying gaps in research and working to address them”

IDENTIFICATION OF RESEARCH PRIORITIESIDENTIFICATION OF RESEARCH PRIORITIES

Development of research priorities – April 2007

Neonatal CSG and ENN: survey of medicines use in Neonatal units – December 2007

ERANET Project – January 2008

Proactive Role (2)

DEVELOPMENT OF RESEARCH PROPOSALSDEVELOPMENT OF RESEARCH PROPOSALS

Respiratory and Cystic Fibrosis CSG (two studies funded)

Cross-CSG Obesity Planning Group – (application submitted to HTA; awaiting outcome)

Gastroenterology, Hepatology and Nutrition CSG IBD and Liver Brainstorming with BSPGHAN (application in progress)

Formulations Subgroup application to NIHR Programme Grants for Applied Research (application in progress)

Proactive Role (3)

OTHER KEY ACTIVITIES/ACHIEVEMENTSOTHER KEY ACTIVITIES/ACHIEVEMENTS

Pharmacy and Pharmacology CSG – Pharmaceutical Translational Research Conference (April 2nd to April 3rd 2009)

External funding obtained from medical research charities to establish new CSGs: MCRN/arc Paediatric Rheumatology CSG; MCRN/BAPN Nephrology CSG (funding from KKR)

The NIHR Medicines for Children Research Network is part of the National Institute for Health Research Clinical Research Network, and forms part of the UK Clinical Research Network. The Networks support and deliver high quality clinical research studies.

Laura PilkingtonClinical Studies Groups Administrator

UK Medicines for Children Research NetworkUniversity of Liverpool Institute of Child Health

Alder Hey Children's Hospital Liverpool, L12 2AP

Tel: 0151 282 4720Fax: 0151 282 4719

[email protected]