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Kuliah Klarifikasi Nursing Care AIDS

Apr 02, 2018

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    Kuliah KlarifikasiNursing Care of Patients withHIV/AIDS

    Kuswantoro Rusca Putra, S.Kp.,M.Kep

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    Anatomic of The Immune System

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    Physiology of The Immune System

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    Understanding The Immune System

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    HIV Antibody Tests

    Enzyme-linked immunosorbent assay (ELISA)

    test

    Western blot testComplete Blood Cell Count/Lymphocyte Count

    CD4+ (410 - 1590 sel/ul)

    CD8+ (190 - 1140 sel/ul)

    Viral Load Testing

    100.000 copies/mlhigh risk for AIDS

    Laboratory Testing & Diagnostic

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    Five Goals of ART

    Decrease the amount of virus in theblood.

    Support and help the immune system.

    Improve quality of life.

    Reduce HIV-related illness and death.

    Possibly reduce transmission of HIV to

    others.

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    Nucleoside (and nucleotide) reversetranscriptase inhibitors (NRTIs):

    NTRIs inhibit the transcription (change) of

    viral RNA into DNA, thereby interfering withviral replication.

    Non-nucleoside reverse transcriptase

    inhibitors (NNRTIs):

    NNRTIs also inhibit the transcription of viralRNA into DNA, but they are chemically

    different than NRTIs.

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    Protease inhibitors (PIs):

    PIs block protease, an enzyme that HIV

    requires for replication.

    Fusion inhibitors:

    Fusion inhibitors disrupt the interaction

    between the HIV virus and the cell surface,

    preventing the fusion of the HIV virus to the

    cell.

    These drugs are not widely available and

    cannot be taken by mouth.

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    ARV drugs

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    Medications for HIV Infection

    Medication Class Action

    Nonnucleoside reversetranscriptase inhibitors

    (NNRTIs)

    Block active site of HIV reversetranscriptase

    Nucleoside/Nucleotide

    Reverse

    Transcriptase Inhibitors(NRTIs)

    Inhibit production of reverse transcriptase

    and viral replication

    Protease Inhibitors (PIs) Bind to active site of HIV protease enzyme,

    which cuts reproduced HIV strands.Interrupt

    formation of mature viral particles and

    reduceviral replication. Rapid resistance

    development if not taken as directed

    Fusion Inhibitors Blocks HIV-1 fusion with the CD4+cell

    membrane to prevent cell entry

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    Cairan

    Estimasi rata-rata tubuh orang dewasa akankehilangan 2.5 L cairan per harinya :

    Sekitar 1.5 L cairan tubuh keluar melalui urin,

    500 ml melalui keluarnya keringat, 400 ml keluar dalam bentuk uap air melalui

    proses respirasi (pernafasan) dan

    100 ml keluar bersama dengan feces (tinja).

    Sehingga berdasarkan estimasi ini, konsumsi

    antara 8-10 gelas (1 gelas 240 ml)

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    Macro Mineral

    Kalsium (Ca)

    Fosfor (P)

    Magnesium (Mg)

    Sulfur (S) Kalium (K)

    Klorida (Cl)

    Natrium (Na)

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    Micro Mineral

    Kromium (Cr)

    Tembaga (Cu)

    Fluoride (F)

    Yodium (I) Besi (Fe)

    Mangan (Mn)

    Silisium (Si) Seng (Zn))

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    Natrium (Na)

    Minimum kebutuhan untuk orangdewasa berkisar antara 1.3-1.6 gr/hari

    (ekivalen dengan 3.3-4.0 gr

    NaCl/hari). konsentrasi berkisar antara 135-145

    mmol/L. Io

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    Kalium (K)

    Konsentrasi antara 3.5-5.0 mmol /L.

    Kebutuhan minimum kalium

    diperkirakan sebesar 782 mg/hari

    Konsentrasi total kalium di dalamtubuh diperkirakan sebanyak 2g/kg

    berat badan. Nam

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    Klorida (Cl)

    Dalam jaringan tubuh diperkirakansebanyak 1.1 g/ Kg berat badan

    Konsentrasi antara 98-106 mmol / L

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    The Cycle of Malnutrition & Infection

    in the context of HIV/AIDS

    I l i Eff t f S ifi

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    Immunologic Effects of Specific

    Micronutrient Deficiences

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    Body Mass Indeks

    BMI =

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    Kategori BMI

    Kurus Kekurangan BB Berat < 17

    Kekurangan BB

    Ringan

    17 18,4

    Normal 18,5 - 25

    Gemuk Kelebihan BB Ringan > 25 - 27

    Kelebihan BB Berat > 27

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    Cara Menghitung Kebutuhan

    Kalori BB Idaman x Keb. Kalori BB IdamanAktivitas Ringan Sedang Berat

    Gemuk 25 30 35

    Normal 30 35 40

    Kurus 35 40 40 - 50

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    Nursing Diagnosis

    Risk for infection related to decreasedimmune function

    Impaired gas exchange related to respiratory

    infection Acute or chronic pain related to neuropathy,

    cancer, infection, or dyspnea

    Fatigue related to HIV infection and/or side

    effects of treatments

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    Diarrhea

    DEFINITION: Passage of loose, unformed stools

    Related factors Infectious processes,medications

    SubjectiveAbdominal pain

    Urgency, cramping

    Objective

    Hyperactive bowel sounds

    At least three loose liquid stools per day

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    DESIRED OUTCOMES/EVALUATION

    CRITERIA

    Client Will (Include Specific Time Frame)

    Reestablish and maintain normal pattern of

    bowel functioning.

    Verbalize understanding of causative factorsand rationale for treatment regimen.

    Demonstrate appropriate behavior to assist

    with resolution of causative factors (e.g.,

    proper food preparation or avoidance ofirritating foods).

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    risk for deficient Fluid VolumeDEFINITION: At risk for experiencing vascular, cellular, or intracellular

    dehydration

    RISK FACTORS

    Excessive losses through normal

    routes (e.g., diarrhea)

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    DESIRED OUTCOMES/EVALUATION

    CRITERIA

    Client Will (Include Specific Time Frame)

    Maintain fluid volume at a functional level

    as evidenced by individually adequate

    urinary output with normal specific gravity,stable vital signs, moist mucous

    membranes, good skin turgor, and prompt

    capillary refill

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    Client/Caregiver Will (Include Specific TimeFrame)

    Identify individual risk factors and appropriate

    interventions.

    Demonstrate behaviors or lifestyle changes to

    prevent development offluid volume deficit.

    DESIRED OUTCOMES/EVALUATION

    CRITERIA

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    risk for Electrolyte ImbalanceDEFINITION: At risk for change in serum electrolyte levels that may

    compromise health.

    RISK FACTORS

    Fluid imbalance (e.g., dehydration,

    water intoxication); diarrhea; vomiting

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    DESIRED OUTCOMES/EVALUATION

    CRITERIA

    Client Will (Include Specific Time Frame) Display laboratory results within normal

    range for individual.

    Be free of complications resulting fromelectrolyte imbalance.

    Identify individual risks and engage in

    appropriate behaviors or lifestyle changes

    to prevent or reduce frequency ofelectrolyte imbalances.

    imbalanced Nutrition: less than body

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    imbalanced Nutrition: less than body

    requirementsDEFINITION: Intake of nutrients insufficient to meet metabolic

    needs

    RELATED FACTORS

    Inability to ingest or digest food; inability to

    absorb nutrients

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    SubjectiveReported food intake less than RDAs

    (recommended daily allowances); lack of

    food Lack of interest in food; aversion to

    eating; reported altered taste sensation;

    perceived inability to digest food

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    Objective Loss of weight with adequate food intake

    Hyperactive bowel sounds; diarrhea

    Poor muscle tone

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    Objective [Abnormal laboratory studies (e.g., decreased

    albumin, total proteins; iron deficiency;

    electrolyte imbalances)]

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    DESIRED OUTCOMES/EVALUATION

    CRITERIA

    Client Will (Include Specific Time Frame) Demonstrate progressive weight gain

    toward goal.

    Display normalization of laboratory valuesand be free of signs of malnutrition

    Verbalize understanding of causative

    factors when known and necessary

    interventions. Demonstrate behaviors, lifestyle changes to

    regain or maintain appropriate weight.

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    risk for InfectionDEFINITION: At increased risk for being invaded by pathogenic

    organisms

    RISK FACTORS Inadequate primary defenses (broken skin,

    traumatized tissue, decrease in ciliary

    action,stasis of body fluids, change in pH

    secretions, altered peristalsis)

    Inadequate secondary defenses (e.g.,

    decreased hemoglobin, leukopenia,

    suppressed inflammatory response) Inadequate acquired immunity;

    immunosuppression

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    Client Will (Include Specific Time Frame) Verbalize understanding of individual

    causative or risk factor(s).

    Identify interventions to prevent or reducerisk of infection.

    Demonstrate techniques, lifestyle changes

    to promote safe environment.

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    FatigueDEFINITION: An overwhelming sustained sense of exhaustion and

    decreased capacity for physical and mental work at usual level

    SubjectiveVerbalization of an unremitting or overwhelming

    lack of energy; inability to maintain usual

    routines or level of physical activity

    Perceived need for additional energy to

    accomplish routine tasks; increase in rest

    requirements

    Tired; inability to restore energy even after sleep

    Feelings of guilt for not keeping up with

    responsibilities

    Increase in physical complaints

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    Objective Lethargic; listless; drowsy; lack of

    energy

    Decreased performance,

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    Client Will (Include Specific Time Frame) Report improved sense of energy.

    Identify basis of fatigue and individual areas

    of control. Perform activities of daily living (ADLs) and

    participate in desired activities at level of

    ability.

    Participate in recommended treatmentprogram.

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    Activity IntoleranceDEFINITION: Insufficient physiological or psychological energy to endure or

    complete required or desired daily activities

    SubjectiveVerbal report of fatigue, weakness

    Exertional discomfort, dyspnea

    [Verbalizes no desire for and/or lack of interest inactivity]

    Objective

    Abnormal heart rate or blood pressure responseto activity

    Electrocardiographic changes reflecting

    arrhythmias or ischemia [Pallor, cyanosis]

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    Client Will (Include Specific Time Frame) Identify negative factors affecting activity

    tolerance and eliminate or reduce their effects

    when possible.

    Use identified techniques to enhance activity

    tolerance.

    Participate in necessary/desired activities.

    Report measurable increase in activity tolerance. Demonstrate a decrease in physiological signs of

    intolerance (e.g., pulse, respirations, and blood

    pressure remain within clients usual range).

    ne ec ve am y erapeu c eg men

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    y p gManagementDEFINITION: Pattern of regulating and integrating into family processes a

    programfor treatment of illness and the sequelae of illness that is

    unsatisfactory for meeting specific health goals

    Subjective Verbalizes difficulty with therapeutic regimen

    Verbalizes desire to manage the illness

    Objective

    Inappropriate family activities for meeting

    health goals

    Acceleration of illness symptoms of a family

    member

    Failure to take action to reduce risk factors;