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Кrok 2 Pharmacy (англомовнi студенти) 2014 рiк 1 1. A sample of biological material contains mercury. Specify the method of mercury isolation: A. Destruction B. Mineralization C. Steam distillation D. Isolation by organic solvents E. Isolation by acidied alcohol 2. A pharmaceutist has to prepare an oil emulsion with menthol. Speci- fy the appropriate way of the active substance incorporation: A. Dissolution in oil B. Dispersion with the addition of ready emulsion C. Dissolution in water intended for diluting the primary emulsion D. Dissolution in the ready emulsion by heating E. Incorporation into the ready pri- mary emulsion 3. It is required to prepare a decoction of bearberry leaves. Specify the ratio of raw materials to the extractant if not indicated in the formulation: A. 1:10 B. 1:20 C. 1:30 D. 1:5 E. 1:400 4. A pharmaceutist prepared an injectable solution of novocaine. What stabilizer had been used? A. Hydrochloric acid solution B. Sodium bicarbonate solution C. Stabilizator of Weibel D. Sodium sulte solution E. Sodium thiosulfate solution 5. A disabled veteran of the WW2 has been prescribed codeine powder. What is the maximum permissible amount of codeine that can be di- spensed by the prescription? A. 0,2 B. 1,0 C. 0,6 D. 1,2 E. 0,1 6. Certain groups of drugs are subject to strict record keeping and storage in pharmacies. Specify a drug that relates to the group of narcotics: A. Ethylmorphine hydrochloride B. Dicaine C. Analgene D. Dephedrinum E. Clonidine 7. Under the analytical normative documents, atropine sulfate should be titrated with hydrochloric acid soluti- on in the anhydrous acetic acid medi- um in the presence of the following indicator: A. Crystal violet B. Thymol blue C. Phenolphtalein D. Methyl orange E. Methylene blue 8. Losartan as a part of treatment of arterial hypertension is contraindi- cated in case of: A. Pregnancy B. Hyperglycemia C. Urine acid diathesis D. Hyperlipidemia E. Hypokalemia 9. Which of the following drugs is used for thrombolytic therapy in case of myocardial infarction? A. Streptokinase B. Heparin C. Phenylinum D. Ticlopidine E. Acetylsalicylic acid 10. At the end of the dug action drug addicts develop severe mental, neurological and somatic disorders. This complex of symptoms is called: A. Withdrawal syndrome B. Tachyphylaxis C. Sensibilization D. Cumulation E. Tolerance 11. Patients with heart failure caused by persisting cardiac and coronary vessel dysfunction can be
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Krok 2 - 2014 Question Paper (Pharmacy)

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Page 1: Krok 2 - 2014 Question Paper (Pharmacy)

Кrok 2 Pharmacy (англомовнi студенти) 2014 рiк 1

1. A sample of biological materialcontains mercury. Specify the methodof mercury isolation:

A. DestructionB. MineralizationC. Steam distillationD. Isolation by organic solventsE. Isolation by acidified alcohol

2. A pharmaceutist has to preparean oil emulsion with menthol. Speci-fy the appropriate way of the activesubstance incorporation:

A. Dissolution in oilB. Dispersion with the addition ofready emulsionC. Dissolution in water intended fordiluting the primary emulsionD. Dissolution in the ready emulsionby heatingE. Incorporation into the ready pri-mary emulsion

3. It is required to prepare a decoctionof bearberry leaves. Specify the ratioof raw materials to the extractant ifnot indicated in the formulation:

A. 1:10B. 1:20C. 1:30D. 1:5E. 1:400

4. A pharmaceutist prepared aninjectable solution of novocaine.What stabilizer had been used?

A. Hydrochloric acid solutionB. Sodium bicarbonate solutionC. Stabilizator of WeibelD. Sodium sulfite solutionE. Sodium thiosulfate solution

5. A disabled veteran of the WW2has been prescribed codeine powder.What is the maximum permissibleamount of codeine that can be di-spensed by the prescription?

A. 0,2B. 1,0C. 0,6D. 1,2E. 0,1

6. Certain groups of drugs are subjectto strict record keeping and storagein pharmacies. Specify a drug thatrelates to the group of narcotics:

A. Ethylmorphine hydrochlorideB. DicaineC. AnalgeneD. DephedrinumE. Clonidine

7. Under the analytical normativedocuments, atropine sulfate should betitrated with hydrochloric acid soluti-on in the anhydrous acetic acid medi-um in the presence of the followingindicator:

A. Crystal violetB. Thymol blueC. PhenolphtaleinD. Methyl orangeE. Methylene blue

8. Losartan as a part of treatmentof arterial hypertension is contraindi-cated in case of:

A. PregnancyB. HyperglycemiaC. Urine acid diathesisD. HyperlipidemiaE. Hypokalemia

9. Which of the following drugs is usedfor thrombolytic therapy in case ofmyocardial infarction?

A. StreptokinaseB. HeparinC. PhenylinumD. TiclopidineE. Acetylsalicylic acid

10. At the end of the dug actiondrug addicts develop severe mental,neurological and somatic disorders.This complex of symptoms is called:

A. Withdrawal syndromeB. TachyphylaxisC. SensibilizationD. CumulationE. Tolerance

11. Patients with heart failurecaused by persisting cardiac andcoronary vessel dysfunction can be

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recommended preparations producedfrom the following herbal raw materi-al:

A. Hawthorn fruitsB. Calendula flowersC. Ginseng rootsD. Aralia rootsE. Barberry roots

12. Rutin exhibits P-vitamin activi-ty. What medicinal plant is used asstarting materials for the industrialproduction of rutin?

A. Fructus Sophorae japonicaeB. Fructus Hippophaes rhamnoidesC. Flores Helichrysi arenariiD. Herba Bidentis tripartitaeE. Herba Polygoni avicularis

13. A patient came to a pharmacy topurchase cowberry leaves. Which ofthe available herbal raw materials canbe offered as a substitute?

A. Folium Uvae ursiB. Rizoma CalamiC. Rizoma et radix SanquisorbaeofficinalisD. Herba Achilleae millefoliiE. Radix Taraxaci officinalis

14. Pharmaceutical warehouse recei-ved a batch of herbal raw materialof cinnamon rose. Under the StatePharmacopoeia, it is required to testthis raw material for the followingactive substances:

A. Ascorbic acidB. FlavonoidsC. TanninsD. Anthracene derivativesE. Essential oil

15. Under the analytical normati-ve documents, prior to directbromatometric determination ofarsenous acid anhydride the followi-ng substance should be added to theanalyzed solution:

A. Potassium bromideB. Potassium nitrateC. Sodium chlorideD. Sodium thiosulfateE. Sodium hydroxide

16. A pharmaceutical analyst ofan analytical laboratory performsquantitative determination of silvernitrate by thiocyanatometry. Whatindicator is used in this case?

A. Iron (III) ammonium sulphateB. Sodium eosinateC. Potassium chromateD. PhenolphtaleinE. Starch

17. A pharmaceutical companyproduces concentrated extracts.Specify the concentration of ethanolin the extractant required for theproduction:

A. 20-40%B. 90-96%C. 70-75%D. 50-60%E. 70-90%

18. A factory workshop producingsuspensions and emulsions is goingto start manufacturing new drugs.What equipment can be used for theultrasound processing of drugs?

A. Liquid whistle, magnetostrictivesourceB. Dismembrator, electrical impulseplasmolyzerC. Disintegrator, liquid whistleD. Rotor-pulsation apparatus, di-smembratorE. Centrifugal mixer with rotatinghousing

19. The ointment workshop ofa pharmaceutical plant launchesproduction of a new ointment. Speci-fy the manufacturing operation thatensures equal distribution of the drugsubstance in the base:

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A. HomogenizationB. Preparation of the baseC. StandardizationD. Pre-packingE. Packaging

20. The aerosol workshop of apharmaceutical plant uses variousgroups of propellants in the producti-on. What propellants relate to thegroup of volatile organic solvents?

A. Methylene chloride, ethylenechlorideB. Freon (CFCs)C. Propane, butane, isobutaneD. Vinyl and methyl chlorideE. Carbon dioxide

21. The phytochemical workshop ofa pharmaceutical plant manufacturesliquid extracts. How many volumeparts of the liquid extract can beproduced from one weight part ofherbal raw material in compliamce wi-th the State Pharmacopoeia?

A. 1 partB. 0,5 partC. 10 partsD. 5 partsE. 3 parts

22. An analytical laboratory receivedcalcium gluconate for analysis. Whatmethod is used for its quantification?

A. ChelatometryB. BromatometryC. IodometryD. Mercurimetric determinationE. Nitritometric determination

23. A chemist of the production unitfor ampouled medicinal preparati-ons analyzes injectable solution ofcalcium chloride. According to therequirements, the analyzed soluti-on should be colorless. To meet thisrequirement, the analyte should becompared to:

A. WaterB. AlcoholC. AcetoneD. Hydrochloric acidE. Chloroform

24. What drug is used as the specificantidote in case of intoxication withiron preparations?

A. DeferoxamineB. Protamine sulfateC. BemegrideD. AtropineE. Penicillamine

25. Specify the type of capsules whi-ch are used for dispensing camphorpowders:

A. ParchmentB. CellophaneC. ParaffinD. WaxedE. Common paper

26. A pharmacy received a formulati-on for an extemporaneouslycompounded medication. Specify thedocument that is used to set the pricefor such medication:

A. Retail price list for drugsB. Inventory reportC. Certificate of qualityD. Cash receipt voucherE. Certificate of analysis

27. A pharmaceutist has prepareda suspension ointment. Specify thesubstance used for this type of oi-ntments:

A. Zinc oxideB. ProtargolumC. MentholD. IchthyolE. Potassium iodide

28. Ergot (Secale cornutum) is usedas an uterotonic agent in obstetricpractice and for the treatmet of cardi-ovascular diseases. The authenticityof the raw materials is proved by thecontent of:

A. ErgotoxineB. AtropineC. HyoscyamineD. ReserpineE. Ajmaline

29. Among the given principles of

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market segmentation select a princi-ple that is used in the study of drugmarket most often:

A. DemographicB. BehavioralC. PsychologicalD. PsychographicE. Socio-economic

30. Personnel records refer to thefollowing type of documents:

A. ManagerialB. PharmaceuticalC. ScientificD. DirectiveE. Reference information

31. A pharmacy received a formulati-on for eye drops containing 1%solution of pilocarpine hydrochlori-de. What substance should be used toensure that the resultant solution isisotonic?

A. Sodium chlorideB. Boric acidC. GlucoseD. Sodium nitrateE. Sodium sulfate

32. A pharmaceutist prepared 10powders containing atropine sulfatein an amount of 0,00005 per dose.What trituration had been used?

A. 1:100B. 1:10C. 1:1000D. 1:50E. 1:20

33. Which of the following anti-hypertensive drugs has potassium-sparing effect?

A. TriamtereneB. FurosemideC. PrazosinD. MetoprololE. Diltiazem

34. Immunochemical test for detecti-on of opiates in urine is carried outon polystyrene plates with the use ofhorseradish peroxidase as a label. Thismethod is classified as:

A. Heterogeneous immunoassayB. Homogeneous immunoassayC. Homogeneous immunofluorescenceD. HeterogeneousimmunofluorescenceE. Heterogeneous radioimmunoassay

35. When developing the systemof marketing communications, acompany should consider thecharacteristics of each tool used formarket promotion of a drug. Whichof the following characteristics is typi-cal for advertising?

A. Depersonalization (non-personalcommunication)B. Non-mass communicationC. Two-way communicationD. All answers are correctE. There is no correct answer

36. Quantitative determination ofpyridine derivatives is performed byacidimetry in nonaqueous medium.What titrant is used for this purpose?

A. Perchlorate acidB. Sulfuric acidC. Nitric acidD. Sodium hydroxideE. Sodium thiosulfate

37. What antiprotozoal agent can berecommended to a female patient wi-th trichomoniasis?

A. MetronidazoleB. PrimaquineC. ChloridinumD. SolusurminumE. Chiniofonum

38. A patient has a history of chronicbronchitis. Recommend him anexpectorant which can be purchasedat a pharmacy to facilitate theexpectoration of thick and viscousmucus:

A. AmbroxolB. FalimintC. GlauventD. LibexinE. Salbutamol

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39. What drug from the group ofcardiac glycosides can be used as analternative for strophanthine if it isnot available at a pharmacy?

A. CorglyconB. IsolanidumC. DigitoxinD. AdonisidumE. Celanidum

40. A pharmacy received the followi-ng formulation:Rp.: Xeroformii Picis Liquidae Betulae ana 3,0

Olei Ricini 100,0M.D.S. For wound anointing.

Specify the dosage form:

A. LinimentB. Hydrophilic ointmentC. PasteD. Combined ointmentE. Solution

41. What is the most commonsymptom of atropine intoxication?

A. Mydriatic pupils with no lightresponseB. Myotic pupils with no light responseC. HyperhidrosisD. BradycardiaE. Reduction of intraocular pressure

42. In order to detect the presenceof thiosulfate ions a pharmaceuticalanalyst added the excess reagent. Theresulting reaction produced a whiteprecipitate which was slowly turningyellow, then brown, and black. Whatsolution was added?

A. Silver nitrateB. Barium chlorideC. Ammonium oxalateD. Lead (II) acetateE. Diphenylamine

43. Quantitative analysis of boric acidcan be performed by alkalimetric ti-tration in the presence of:

A. MannitolB. Ethyl alcoholC. Ammonia bufferD. Mercury (II) acetateE. Nitric acid

44. A customer came to a pharmacyand presented the prescription forTramadol tablets. For how long sucha prescription must be kept at apharmacy?

A. 5 years, exclusive of the currentyearB. 1 year, exclusive of the current yearC. 6 months, exclusive of the currentyearD. 10 years, exclusive of the currentyearE. 1 month, exclusive of the currentyear

45. A 6-year-old child with pneumoniahad been administered an antibiotic.After treatment the child lost thehearing. What group of antibiotics mi-ght have caused this complication?

A. AminoglycosidesB. CephalosporinsC. MacrolidesD. Natural penicillinsE. Semi-synthetic penicillins

46. Suppositories are prepared byvarious methods such as rolling,pouring, pressing. What base is usedin the pouring method?

A. ButyrolumB. ParaffinC. Cocoa butterD. VaselineE. Coriander oil

47. Select the optimal antibacterialdrug for the treatment of mycoplasmapneumonia:

A. RovamycinB. GentamicinC. PenicillinD. AmpicillinE. Amoxiclav

48. Quantitative determination ofpesticides in organic extracts after theisolation from the biological materi-al can be done by various methods.What method of quantitative analysisof chlorophos is based on measuringthe peak height parameter?

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A. Gas-liquid chromatographyB. Thin-layer chromatographyC. PhotometryD. ArgentometryE. Biochemical method

49. An analytical chemist of thequality control department of apharmaceutical plant has to determi-ne the average weight of glibenclami-de tablets. How many tablets shouldbe tested for this purpose?

A. 20B. 10C. 5D. 50E. 30

50. A pharmacy received 10 kgof hawthorn tincture which waspackaged in 80 ml bottles. Thisoperation should be recorded in thefollowing document:

A. Journal of laboratory and pre-packing operationsB. Receipt for the ordered medicationC. Consolidated registerD. CashbookE. Formulation journal

51. Employees of a pharmacy receivehourly rate wage and bonuses basedon individual performance. Whatdocument is issued when calculatingthe payroll advance?

A. Payroll recordB. Inventory reportC. InvoiceD. Cash receipt voucherE. Cash payment voucher

52. Help a medical student to selectan adrenergic drug for the treatmentof anaphylactic shock:

A. Epinephrine hydrochlorideB. ClonidineC. GalazolinD. FenoterolumE. Isadrinum

53. A 5-year-old child had acci-dentally drunk a bottle of eye drops.After 30 minutes the child developed

shortness of breath, difficult swallowi-ng, voice hoarseness, dilated pupils,hyperthermia. Which of the drugs mi-ght have induced the described mani-festations?

A. AtropineB. AdrenalineC. MesatonumD. PilocarpineE. Novocaine

54. A patient purchased peppermi-nt leaves at a pharmacy. Whatrecommendations on infusing thisherbal raw material must be given bythe pharmaceutist?

A. The infusion is to be prepared in atightly closed vesselB. The infusion is to be prepared on anopen fireC. The infusion is to be prepared atroom temperatureD. The extract is to be immediatelyfiltered after infusingE. The extract is to be artificiallycooled 15 minutes after infusing

55. It is required to prepare 50 g ofzinc ointment for a patient. Whatamount of zinc and vaseline must beweighed out by a pharmaceutist?

A. 5,0 and 45,0 gB. 10,0 and 40,0 gC. 2,5 and 40,0 gD. 1,0 and 49,0 gE. 0,5 and 49,5 g

56. Sterilization methods applied forthe preparation of drugs under asepticconditions can be differentiated intophysical, mechanical, and chemicalones. Specify the chemical method ofsterilization:

A. Addition of preservativesB. Dry heat sterilizationC. Radiation sterilizationD. Pressure steam sterilizationE. UV light sterilization

57. A patient had been given aninjection of 0,25% novocaine solutionfor the purpose of anaesthetization.Suddenly the patient developed red

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spots, intense sweating, tachycardia,bronchospasm, edema of nasalmucosa. What is the cause of thiscomplication?

A. Immediate allergyB. Delayed allergyC. Local irritationD. TachyphylaxisE. Withdrawal syndrome

58. What is the mechanism of actionof diclofenac sodium?

A. It blocks cyclooxygenaseB. It activates the synthesis ofphosphodiesteraseC. It inhibits cholinesteraseD. It activates adenylate cyclaseE. It inhibits phosphodiesterase

59. In order to identify deoxycorti-costerone acetate a pharmaceuticalanalyst performed a steroid cyclereaction which produced cherry-redcolor and green fluorescence. Whatreagent was added?

A. Concentrated sulfuric acidB. Iodine solutionC. Iron (III) chloride solutionD. ChloroformE. Potassium hydroxide solution

60. When investigating the case ofdrug intoxication, the expert commi-ssion should find out, whether intoxi-cation had been caused by opium oromnopon. For this purpose it is requi-red to conduct an addititional test for:

A. Meconic acid and meconinB. MorphineC. PapaverineD. ThebaineE. Codeine

61. Within an accounting period apharmacy has been providing thepopulation with the finished medicati-ons. What business transaction willhave an effect on increasing inventoryof the pharmacy?

A. Arrivals from the pharmaceuticalwarehouseB. Markdown according to the pre-packing journalC. Write-off of goodsD. Write-off of low-value inventoryE. Salary accounting

62. Which of the following non-steroid anti-inflammatory agents hasthe least harmful effect on the mucosaof the gastrointestinal tract?

A. NimesulideB. DiclofenacC. IndomethacinD. PiroxicamE. Acetylsalicylic acid

63. A manufacturing enterprise plansto retail a new drug through thecorporate network of pharmacies.What strategy of drug distribution willbe used?

A. DirectB. Multi-echelonC. FlexibleD. Horizontal integrationE. Vertical integration

64. When preparing an ointment withcastor oil and vaseline a pharmaceuti-st failed to obtain a homogeneoussystem. What is the most likely causeof incompatibility between thesecomponents?

A. Immiscibility of the ingredientsB. Limited solubilityC. Release of water of crystallizationD. CoagulationE. Adsorption

65. In order to identify the toxicsubstance which was extractedfrom the acidic aqueous extract byan organic solvent, a toxicologi-st performed a murexide test whi-ch resulted in development of pinkcoloration. This indicates presence ofthe following substance in the sample:

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A. BarbamylB. MorphineC. StrychnineD. CocaineE. Atropine

66. Woolly foxglove is used as rawmaterial for the production of thefollowing drug:

A. LantosidumB. CorglyconC. DigitoxinD. AdonizidE. Erysimosidum

67. A 60-year-old female patient hasa history of essential hypertensi-on (stage II), ischemic heart di-sease, bronchial asthma. After thecorrection of pharmacotherapy, apatient experienced an attack ofbronchospasm, and an escalation ofdyspnea. What drug had caused thecomplication?

A. PropranololB. NifedipineC. AminophyllineD. MucaltinumE. Salbutamol

68. A pharmaceutical analyst with a6-year length of service is on a sickleave due to temporary disability. Heis entitled to the sickness allowance inthe amount of:

A. 80% of average wageB. 50% of average wageC. 100% of average wageD. 70% of average wageE. 30% of average wage

69. Sage leaves procured for theproduction of essential oil should bedried at a temperature of:

A. 25-30oCB. 50-60oCC. 100oCD. 60-70oCE. 70-80oC

70. Which of the following antibioti-cs can be identified by means of themaltol formation test?

A. Streptomycin sulfateB. Doxycycline hydrochlorideC. AmoxicillinD. Lincomycin hydrochlorideE. Kanamycin monosulfate

71. What is the main mechanism ofaction that underlies the bactericidaleffect of penicillin on the coccal flora?

A. Disruption of synthesis of themicrobial cell wallB. Inhibition of protein synthesisC. Damage to the cytoplasmicmembrane permeabilityD. Activation of the immune system ofthe macroorganismE. Phagocytic activity of leukocytes

72. What is the drug of choice for thetreatment of acute pyelonephritis in apregnant woman in the I trimester?

A. AmoxicillinB. NorfloxacinC. BiseptolumD. GentamicinE. Chloramphenicol

73. What is the most suitable drugthat can be recommended for thetreatment of rhinitis accompanying anARVI in a 7-month-old child?

A. 0,9% warm water solution of NaClB. NaphthyzinC. GalazolinD. PinosolE. Boromentol ointment

74. What drug may cause thedevelopment of constipation in pati-ents undergoing combined therapyfor arterial hypertension?

A. VerapamilB. FurosemideC. TrimetazidineD. PananginumE. Acetylsalicylic acid in small doses

75. In a pharmaceutical company bothAmerican and Japanese managementstyles are used. Select a characteristicfeature of the Japanese managementstyle:

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A. Collective responsibilityB. Individual decision-making processC. Fast evaluation and careeradvancementD. Clearly formalized managementstructureE. Short-term employment

76. Drug A is in the stage of marketsaturation. In order to push upintensive sales, management of themanufacturing company decided touse the following type of advertising:

A. AggressiveB. InformationalC. Personal salesD. Sales promotionE. Public relations

77. A person got poisoned withalcohols. What alcohol derivatives areused for the analysis by the method ofgas-liquid chromatography?

A. Alkyl nitritesB. Alkyl nitratesC. Alkyl sulfitesD. Alkyl sulfatesE. Alkyl acetates

78. A pharmaceutical analyst identifi-es the substance of potassium acetate.What reagent confirms the presenceof potassium cation in the analyte?

A. Tartaric acidB. Sodium hydroxideC. Potassium permanganateD. Iron (III) chlorideE. Zinc oxide

79. A pharmaceutical analyst testspotassium bromide for magnesiumand alkaline earth metals impuri-ty. What solution is used for thispurpose?

A. Sodium edetateB. Potassium permanganateC. Hydrochloric acidD. Silver nitrateE. Sodium nitrite

80. A patient with a history of essenti-al hypertension has been admini-stered lisinopril. What is the mechani-

sm of action of this drug?

A. It inhibits ACEB. It inhibits alpha-adrenergicreceptorsC. It inhibits beta-adrenergic receptorsD. It stimulates beta-adrenergicreceptorsE. It inhibits M-cholinergic receptors

81. A male patient has been admi-nistered an antiulcerant that blockshistamine receptors of the gastricmucosa. What drug is it?

A. FamotidineB. OmeprazoleC. AlmagelumD. Atropine sulfateE. Pirenzepine

82. Stimulation of beta-cells of thepancreas causes the hypoglycemiceffect of the following drug:

A. GlibenclamideB. PrednisoloneC. Adrenaline hydrochlorideD. RetabolilumE. Heparin

83. A pharmaceutist prepared an oi-ntment by the following formulation:Rp.: Tannini 0,2

Lanolini 3,0Vaselini 10,0M. ut f. ung.D.S. To anoint the affected skin areas.

What method of tannin incorporationwas used?

A. Water dissolution, emulsificationwith anhydrous lanolinB. Trituration with liquid petrolate ina mortar by Deryagin ruleC. Dissolution in molten vaselineD. Trituration with an alcohol in amortar, blending with the baseE. Dissolution in liquid petrolate

84. Business transactions are di-splayed in the accounts. The entryin the account ledger that is madeto record the incoming of economicresources is called:

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A. DebitB. EquityC. CreditD. AssetsE. Liabilities

85. Within the matrix of BostonConsulting Group, a certain drugrefers to a group of products called"milking cash cows". Specify the stageof the lifecycle of this drug:

A. MaturityB. IntroductionC. DeclineD. GrowthE. Withdrawal

86. An analytical laboratory has beencommissioned to prove the presenceof ethylenediamine in aminophylli-ne. Which of the following reagentsmakes it possible to detect ethylenedi-amine?

A. Copper (II) sulfateB. Sodium hydroxideC. Concentrated sulfuric acidD. Silver nitrateE. Barium chloride

87. A patient has glaucoma.Recommend him a drug of the M-cholinomimetic group:

A. Pylocarpine hydrochlorideB. Ephedrine hydrochlorideC. Sulfacyl sodiumD. Atropine sulfateE. Laevomycetin

88. Advise an internship doctor onwhy iron preparations should not beadministered together with antacids:

A. This causes malabsorption of ironB. This causes increased binding toblood proteinsC. This prevents deposition of iron inthe bodyD. This increases intoxication withiron preparationsE. This accelerates elimination of ironpreparations

89. A female patient with pneumoniahas been administered doxycycline

hydrochloride. This drug relates to thefollowing group of antibiotics:

A. TetracyclinesB. AminoglycosidesC. MacrolidesD. CephalosporinsE. Penicillins

90. A pharmacy received the goodsaccording to the accompanyingdocumentation. Who is responsiblefor keeping the record of medicinesreceived by a business entity?

A. Authorized representativeB. Pharmacist of the pharmacyC. Materially responsible personD. TrusteeE. Chief accountant

91. Under the SPh of Ukraine, oneof the reactions for the detection ofcalcium cation presence in drugs is thereaction with:

A. Glyoxal-hydroxyanilB. HydroxyquinolineC. HydroxylamineD. AlizarinE. Sulfuric acid

92. A patient with cholelithiasisshould be administered the followingdrug for the dissolution of cholesterolgallstones:

A. Ursodeoxycholic acidB. Gamma-aminobutyric acidC. Acetylsalicylic acidD. Citric acidE. Mefenamic acid

93. A patient with acute heart fai-lure and cardiac glycoside intolerancewas given an injection of dobutamine.What is the mechanism of its action?

A. Stimulation of β1-adrenoceptorsB. Stimulation of α1-adrenoceptorsC. Block of K+-, Na+-ATPaseD. Inhibition of phosphodiesteraseE. Stimulation of M -cholinergicreceptors

94. Which of the methods to fillampoules with injectable solutions

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makes it possible to protect capillari-es from contamination with thick andviscous solutions?

A. SyringeB. VacuumC. Turbo vacuumD. Vapor condensationE. Squeezing-through

95. When setting up a joint-stockcompany the founders discussed theissues of financial liability. What is theliability of the board members in ajoint-stock company?

A. Limited to the value of their sharesB. Limited to the double amount ofdepositsC. Limited to the contributions to thestatutory fund and their propertyD. Limited to the amount of depositsE. Unlimited and solidary

96. In order to verify the purity of theessential oil, some ethanol was addedinto the test tube with peppermintoil. The mixture became turbid. Thismeans that the peppermint oil contai-ns the following impurity:

A. Fatty oilB. PhenolC. AcetoneD. Ethyl acetateE. Diethyl ether

97. 5% solution of methylcelluloseis used as a stabilizer for preparinga suspension of the following drugsubstance:

A. Terpine hydrateB. Magnesium oxideC. StarchD. Bismuth nitrate basicE. Zinc oxide

98. An analytical chemist of thequality control department of apharmaceutical plant can prove thepresence of the cation in the testsubstance with a solution of potassi-um:

A. PyroantimonateB. ChlorideC. Ferrocyanide (III)D. HydroxideE. Nitrate

99. Magnesium peroxide identificati-on is performed by the reaction ofperchromic acid formation. Whatcolor is produced as a result of thisreaction?

A. BlueB. RedC. GreenD. BlackE. Yellow

100. A forensic medicine laboratoryreceived some biological material. Itwas to be tested for the presence oftrichlorfon and dichlorvos. For theirisolation a toxicologist infuses themwith:

A. ChloroformB. Water alkalized with ammoniasolutionC. Propanol acidified with oxalic acidD. Ethanol acidified with oxalic acidE. Water acidified with sulfuric acid

101. Pharmacies prepare injectablesolutions. Which solution is preparedwithout any stabilizer?

A. Sodium bicarbonate solutionB. Sodium thiosulfate solutionC. Solution of caffeine sodiumbenzoateD. Glucose solutionE. Novocaine solution

102. Ammifurinum contains furocumari-nes. These biologically activesubstances are derived from:

A. Fruits of large ammiB. Fruits of psoraleaC. Fruits of common parsnipD. Fruits of toothpick ammiE. Rhizomes and roots of angelica

103. Quality of ampouled injecti-on solutions is tested as to variousparameters. How many ampullae areto be checked for assessing the quality

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of sealing (hermeticity)?

A. 100%B. 97%C. 80%D. 75%E. 50%

104. A pharmacy compoundssuspensions. What substance can beused for preparing a suspension wi-thout adding the stabilizer?

A. Magnesium oxideB. CamphorC. SulfurD. MentholE. Phenyl salycylate

105. All employees are entitled toannual leave. What is the durationof the additional leave for pharmacyemployees with non-standard worki-ng hours?

A. Seven calendar daysB. The additional leave is not grantedC. Ten calendar daysD. Twenty calendar daysE. Thirty calendar days

106. One of the packagings stored atthe warehouse of finished productshas a damaged label. It is known thatthe drug substance in this packagi-ng relates to alkaloids. In course ofgroup qualitative tests for alkaloidsthe drug substance reacted positivelywith murexide. Further identificationof the drug substance should be limi-ted to the following group of derivati-ves:

A. PurineB. QuinolineC. TropaneD. IsoquinolineE. Indole

107. Industrial, labor and socio-economic relations between the headof a pharmaceutical company and theemployees are regulated by:

A. Collective agreementB. Employment agreementC. Corporate codeD. ContractE. Statute

108. A pharmacy received the followi-ng formulation:Rp.: Dibazoli 0,05

Papaverini hydrochloridi 0,15Sacchari 2,5M. fiat pulv.Divide in partes aequales №10.

Specify the weight of a single powderdose:

A. 0,27B. 2,7C. 0,25D. 0,26E. 0,30

109. Xenobiotics are metabolized inthe body. The main metabolite of theacetic acid is:

A. AcetaldehydeB. Methyl alcoholC. Isopentyl alcoholD. Formic acidE. Valeric acid

110. Under the SPhU, the pharmacopei-al preparation "Aether anaestheti-cus"is not allowed to have peroxi-de impurity. What reagent should beused to detect peroxides?

A. Solution of starch and potassiumiodideB. Solution of starch and potassiumtetraiodomercurateC. Solution of starch and potassiumbromideD. Grade reagentE. Lugol’s reagent

111. Arrangement of drugs in theretail space of a pharmacy can becharacterized as either strong orweak. What arrangement of drugs isregarded as weak?

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A. On the lower shelvesB. At the intersection of the ranks ofshelvesC. The shelves on the right side as thebuyers pass alongD. Cashier desk zoneE. Zones with a good frontal look

112. When calculating the personalincome tax, the tax social privilege istaken into account. Its rate dependson a certain statutory amount. Speci-fy this amount:

A. Minimum statutory wageB. Cost of living for one personC. Cost of living for incapacitatedpersonsD. Maximum payroll fundE. Cost of living for children aged 6 to18 years

113. Fatty oils containing unsaturatedfatty acids are used for theprophylaxis of atherosclerosis. Specifythe starting materials of herbal originthat contain fatty oil:

A. Pumpkin seedB. Ispaghula seedC. Chestnut seedD. Parsnip fruitsE. Psoralea fruits

114. The phytochemical workshopof a pharmaceutical plant producesbiogenic stimulators from differentstarting materials. Specify the bi-ogenic stimulators of animal origin:

A. Vitreous body, placental suspensionfor injections, plasmolum, solcoserylB. Liquid aloe extract, aloe liniment,aloe juice, biossedumC. Peloidinum, humisolum, torfotum,Fibs Rro injectionibusD. Liquid aloe extract, aloe liniment,plasmolumE. Peloidinum, humisolum, torfotum,plasmolum, solcoseryl

115. A pharmacy network recei-ved a batch of raw material withoutanalysis protocol. It was identifiedas marshmallow root by the externalcharcteristics. The reaction with 5%alkali liquor was positive. This indi-

cates the presence of:

A. SlimesB. GumsC. StarchD. PectinsE. Cellulose

116. A pharmaceutical analyst testsanhydrous glucose for purity accordi-ng to the requirements of the SPhU.Inadmissible barium impurity can bedetected by using the following acid:

A. SulphuricB. HydrochloricC. AceticD. NitricE. Perchloric

117. The chemical name 1-benzoyl-5-ethyl-5-phenyl-barbituric acid standsfor the following substance relating tobarbiturates:

A. BenzonalB. BarbitalC. PhenobarbitalD. HexenalE. Benzobamil

118. What herbal drug produced formalkaloid-containing raw materials canbe recommended for neurasthenia,insomnia, menopausal disorders?

A. NovopassitB. ErgotamineC. Glaucine hydrochlorideD. Securinine nitrateE. Vinblastine

119. A pharmaceutist prepares 3000mL of valerian root infusion fora hospital department. The givenamount of extract should be infusedin a water bath for:

A. 25 minutesB. 45 minutesC. 15 minutesD. 10 minutesE. 30 minutes

120. A pharmaceutist has prepared asolution of menthol oil. Specify thedissolution temperature of the activesubstance:

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A. 40-50oCB. 60-70oCC. 30-40oCD. 70-80oCE. 20-30oC

121. Forensic toxicological analysis ofa mineralizate revealed copper. Forthe initial detection of copper ions thefollowing substance is used:

A. Plumbum diethyldithiocarbamateB. Sodium diethyldithiocarbamateC. DithizoneD. DiphenylcarbazideE. Diphenylamine

122. A patient has been found to havepesticide intoxication. Biochemical(cholinesterase) test was positive.What pesticide is likely to have causedthe intoxication?

A. DichlorvosB. DDTC. HexachlorocyclohexaneD. HeptachlorE. Ethyl mercury chloride

123. As a result of condensationof substituted malonic esters andurea the derivatives of the followingsubstance are obtained:

A. PyrimidineB. PyridazineC. PyrazoleD. PyridineE. Pyrazine

124. Which of the followingophthalmic dosage forms is producedonly industrially?

A. Ophthalmic insertsB. Ophthalmic ointmentsC. Eye dropsD. Eye washesE. Eye rinses

125. What medication should beused as an antidote to eliminate therespiratory depression caused by anoverdose of a narcotic analgesic?

A. NaloxoneB. CordiamineC. AethimizolumD. CamphorE. Ammonia

126. Fenofibrate relates to the followi-ng pharmacological group:

A. HypolipidemicsB. Fibrinolysis inhibitorsC. HypnoticsD. AntihypertensivesE. Indirect anticoagulants

127. Which of the following vaginaldosage forms relate to the officinalformula, that is, are prepared in apharmacy?

A. PessariesB. Vaginal tabletsC. Vaginal capsulesD. Vaginal foamsE. Vaginal tablets for preparing soluti-ons and suspensions

128. The glidants aerosil or magnesi-um stearate together with talc areadded to the excipients in hard gelatincapsules in order to facilitate thefollowing property:

A. Powder flowabilityB. HomogenityC. Moisture regulationD. Homogeneous mixingE. Compactibility

129. A student has been prescribed atonic. This may be the tincture of thefollowing medicinal plant:

A. Rhodiola roseaB. Common yarrowC. Java tea (orthosiphon aristatus)D. Purple foxgloveE. Black locust

130. A 25-year-old female patient hadbeen taking antibiotics for 7 days,the disease was complicated by thedevelopment of intestinal dysbiosis.This complication should be treatedby the drugs of the following group:

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A. ProbioticsB. AntispasmodicsC. CholereticsD. AntacidsE. Adaptogens

131. Which group of adjuvantsincludes polyvinyl alcohol used underthe SPhU?

A. ProlongatorsB. PreservativesC. pH adjustersD. AntioxidantsE. Isotonizing agents

132. Which of the following drugsshould be used for prevention ofbronchial asthma attacks?

A. Cromolyn sodiumB. SalbutamolC. DrotaverineD. Diphenhydramine hydrochlorideE. Ambroxol

133. A pharmaceutist has to preparea medication by the followingformulation:Rp.: Natrii hydrocarbonatis 2,0

Natrii benzoatis 1,5Liquoris Ammonii anisatis 4 mlAquae Mentae 100 mlM.D.S. 1 tablespoon3 times a day.

Specify the component that is addedin the first place:

A. Mint waterB. Sugar syrupC. Liquoris Ammonii anisatisD. Sodium hydrogen carbonateE. Sodium benzoate

134. A pharmaceutist prepares an oi-ntment under aseptic conditions onthe sterile ointment base, namelythe composition of vaseline andlanoline at a ratio 6:4. The drugsubstance is incorporated by suspensi-on type. Such technique of ointmentpreparation is typical for the followi-ng substance:

A. Benzylpenicillin sodium saltB. Sodium chlorideC. Thiamine chlorideD. Pilocarpine hydrochlorideE. Sodium sulfate

135. Under the chemico-toxicologicalclassification, toxic compounds aregrouped according to the methodof their isolation from the biologi-cal material. What compound can beisolated by steam distillation?

A. Chloral hydrateB. AtropineC. ArsenicumD. AnalgeneE. Diazepam

136. Toxic medicines are isolated frombiological material at a certain pHlevel of the medium. What substanceis extracted from acidic aqueousextracts?

A. CaffeineB. ChlorpromazineC. AtropineD. MorphineE. Cocaine

137. What drug is indicated in caseof taking an overdose of depolarizingmuscle relaxants?

A. Neostigmine methylsulfateB. MetoprololC. NaloxoneD. Magnesium sulfateE. Unithiol

138. A 20-year-old female patienthas been administered bicillin forrheumatic fever prophylaxis. Speci-fy the frequency of bicillin-5 admini-stration:

A. Once every 3 weeksB. Once per weekC. Once in 3 daysD. Once per monthE. Once a day

139. A 65-year-old male patientcomplains of nausea, vomiting,lethargy, seeing yellow spots in frontof his eyes. The patient takes dai-

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ly 0,25 mg of digoxin, 100 mg ofaspecardum, 50 mg of metoprolol.What pathological condition is thissyndrome typical for?

A. Glycoside intoxicationB. Food poisoningC. Withdrawal syndromeD. TachyphylaxisE. Hypersensitivity reaction

140. Vincamine alkaloid reducesblood pressure, has a pronouncedsedation effect, as well as hemostaticand anti-inflammatory effect. Whatherb is the source of this alkaloid?

A. Common periwinkleB. Thick-fruited pagoda treeC. Bluish larkspurD. Northern wolfsbaneE. Yellow water-lily

141. The galenical preparationsworkshop produces belladonna ti-ncture. Specify the required ratio forthis dosage form:

A. 1:10B. 1:5C. 1:20D. 1:2E. 1:1

142. Pharmaceutical plants produceointments on various bases. Specifythe ointment base having the mostpronounced osmotic properties:

A. Polyethylene oxideB. SiliconC. Vaseline, lanolinD. Methyl celluloseE. Hydrogenated fat

143. A patient with acute heart failurehas been administered an adrenomi-metic agent. What drug is it?

A. DobutamineB. DigoxinC. CorglyconD. MetoprololE. Salbutamol

144. Oil liniments are produced withfatty oils used as a base. What kind ofoil should be used by a pharmacist if it

was not specified in the formulation?

A. Sunflower oilB. PetrolatumC. Cod-liver oilD. Sesame oilE. Eucalyptus oil

145. A pharmacy received aformula for an alcohol solution ofmethylene blue with unspecifiedalcohol concentration. In this case, apharmacutist must use ethyl alcoholof the following concentration:

A. 60%B. 90%C. 70%D. 96%E. 40%

146. Production unit for ampouledmedicinal preparations producesprocaine hydrochloride solution. Thissolution is stabilized by adding:

A. 0,1 mol/l of hydrochloric acidsolutionB. 0,1 mol/l of sodium hydroxidesolutionC. 0,1 mol/l of sodium hydrogencarbonate solutionD. 20,0 of sodium hydrogen carbonateE. 1,5 g of amino-propylene glycol

147. Recommend a drug for thetreatment of tachyarrhythmia epi-sodes:

A. PropranololB. AdrenalineC. AtropineD. Caffeine sodium benzoateE. Dobutamine

148. A 35-year-old female customercame to a pharmacy to purchasea medicine for the prevention ofinfluenza. Which of the followingdrugs can be recommended?

A. RimantadineB. AcyclovirC. RibavirinD. GanciclovirE. Lamivudine

149. Employees of a company can

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be instructed to go on a businesstrip by the orders of the company’shead. Specify the deadline for submi-ssion of an expense report after theemployee’s return from the trip:

A. 3 daysB. 4 daysC. 5 daysD. 6 daysE. 2 days

150. A pharmaceutical analystanalyzes a dosage form containing zi-nc sulfate. What reagent enables himto confirm the presence of the zinccation in the analyte?

A. Sodium sulfideB. Ammonium chlorideC. Potassium ferrocyanideD. Silver nitrateE. Sodium tetraphenylborate

151. Lily of the valley is widelyregarded as a cardiac stimulant andsedative. During the raw materialprocurement, the following plant mayoccur in the harvested crop:

A. Round-leaved pyrolaB. Spring adonisC. Treacle-mustard (Erysimum chei-ranthoides)D. Viola tricolorE. Viola arvensis

152. A pharmaceutist prepares aninfusion at a ratio of 1:30. What herbalraw material will be used?

A. Lily of the valley grassB. Marshmallow rootC. Sage leavesD. Oak barkE. Shoots of Marsh Labrador tea

153. A pharmaceutist has preparedvaginal suppositories. Specify theform of these suppositories:

A. MarblesB. TorpedoC. CylinderD. ConeE. Sticks

154. Under the SPhU (appendix 2),leaves of ginkgo are standardized bythe content of:

A. FlavonoidsB. SaponinsC. AlkaloidsD. CoumarinsE. Chromones

155. A clinical pharmaceutist invitedto a medical conference made a reporton the antiviral drug acyclovir. Whatis its mechanism of action?

A. It inhibits the synthesis of nucleicacidsB. It blocks the synthesis of the cellwallC. It increases the permeability of thecell membraneD. It antagonizes with PABAE. It inhibits the synthesis of proteins

156. What kind of marketing is provi-ded in case of negative demand forgoods and services, that is, in a si-tuation when the demand is absentin a substantial part of the potentialmarket?

A. ConversionB. StimulatingC. RemarketingD. Synchro marketingE. Demarketing

157. Prescriptions for the controlleddrugs dispensed under the rei-mbursement program (except for thenarcotic and psychotropic preparati-ons in substance) are issued on thefollowing prescription form:

A. №1 in duplicateB. №1, single copyC. №1 and № 3D. №3 in duplicateE. №3, single copy

158. In case of the planned closure ofa pharmacy for repair works, techni-cal re-equipment or other works, abusiness entity is obliged to give awritten notice to the Territorial StateInspectorate for Quality Control ofMedicines in advance, but not later

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than:

A. 5 days in advanceB. 10 days in advanceC. 7 days in advanceD. 3 days in advanceE. 12 days in advance

159. Pharmacy №7 is engaged in bothsales and production. What operati-ons ARE NOT REGISTERED in thejournal of laboratory and prepackingworks?

A. Extemporaneous compounding ofdosage formsB. Preparation of semi-finishedproductsC. Preparation of concentrated soluti-onsD. Preparation of commercially avai-lable medicationsE. Packaging of finished products incertain amounts

160. Specify a drug having ananaleptic and psychostimulant effect:

A. Caffeine sodium benzoateB. Neostigmine methylsulfateC. DiazepamD. CorglyconE. Diclofenac sodium

161. What medicines are used to eli-minate bronchospasm?

A. β-adrenergic agonistsB. β-blockersC. α-adrenergic agonistsD. Cholinesterase inhibitorsE. M-cholinomimetics

162. Alkaloid glaucine has an anti-tussive effect that is stronger andlonger if compared to that of codeine,and exhibits no narcotic side effects.What medicinal plant contains glauci-ne?

A. Yellow hornpoppyB. CelandineC. Thermopsis lanceolataD. DaturaE. Henbane bell (Scopolia carniolica)

163. Drug plant Dioscorea nipponi-ca is the starting materials for

the production of Polysponinumdrug which is used in the complextreatment of atherosclerosis. Specifythe active compounds of dioscorea:

A. Steroid saponinsB. AlkaloidsC. Essential oilD. Cardiac glycosidesE. Triterpene saponins

164. A hypertensive patient had beenadministered a diuretic as a part of thecombined therapy. The administereddrug caused hypokalemia. Specify thisdrug:

A. HydrochlorothiazideB. AmilorideC. SpironolactoneD. AllopurinolE. Triamterene

165. A pharmaceutical factoryproduces herbal juice from fresh rawmaterial. What operation should beperformed at the stage of juice purifi-cation?

A. Heating followed by rapid coolingB. SedimentationC. AdsorptionD. FiltrationE. Crystallization

166. Cash receipts and paymentsat a pharmacy are recorded in thecashbook. Which of the followi-ng cash transactions IS NOTREGARDED as a receipt transacti-on?

A. Issuing funds to be accounted forB. Recognizing cash receipts fromsales at a pharmacyC. Recognizing cash receipts fromsales at pharmacy outlets and kiosksD. Return of unused disbursementfundsE. Recognizing accrued salaries andadvance payable

167. What system includes a set oflegal rules that regulate the amounts,forms, methods and time limits forcollecting taxes and tax-like chargesthat enable the state to perform its

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functions?

A. TaxB. AccountingC. StatisticD. ReportingE. Remuneration of labor

168. Phytochemical workshop ofa factory manufactures pancreatin.What is the starting material for obtai-ning pancreatin?

A. Pancreas of pigs or cattleB. Gastric mucosa of pigsC. Lungs of cattleD. Heart of cattleE. Egg white

169. In case of simultaneous useof metronidazole and oral anti-coagulants derived from coumarinpatients must be warned about:

A. Potentiation of anticoagulantseffect and the risk of bleedingB. Reduction of anticoagulants effectC. Potentiation of metronidazole effectD. Reduction of metronidazole effectE. Higher neurotoxicity

170. Specify the principle of thepharmacy accounting which compli-es with the following definition: "Thisprinciple provides for continuousfollowing the adopted accountingpolicy. Any changes to the accounti-ng policy must be well-grounded andfixed in the financial statements":

A. ConsistencyB. PeriodicityC. Expenses against revenues matchi-ngD. Full disclosureE. Going concern

171. At a maternity hospital apregnant woman with weak uterinecontractions has been administeredoxytocin. This drug relates to thefollowing pharmaceutical group:

A. Pituitary hormone preparationsB. Thyroid hormone preparationsC. Anabolic steroidsD. Mineral corticoidsE. Glucocorticoids

172. What factor underlies themechanism of the analgesic effect ofmorphine hydrochloride?

A. Stimulation of opiate receptorsB. Inhibition of histamine receptorsC. Inhibition of phosphodiesteraseD. Stimulation of adenylate cyclaseE. Inhibition of cholinesterase

173. Analytical and control laboratorydetermines quality of fatty oilsby using certain chemical indices.Specify the chemical index that isdemonstrative of the fatty oil drying:

A. Iodine absorption numberB. Acid numberC. Saponification numberD. Ester numberE. Peroxide number

174. The head of a pharmaceuticalcompany "Azalea"applies differenttypes of control. The control whichstarts with logging in to the system oforganization before commencementof work and is exercised throughrules, procedures, etc. refers to:

A. Preliminary controlB. Current controlC. Final controlD. Decentralized controlE. Centralized control

175. A 30-year-old male patient di-agnosed with acute osteomyelitis hasbeen administered an antibiotic thatis highly effective in penetrating thebone tissue. What drug has beenchosen?

A. LincomycinB. Bicillin 3C. PenicillinD. Polymyxin-ME. Ampicillin

176. A pharmaceutist dispenseddoxycycline to a patient and

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recommended to abandon dairyproducts. What is the reason for suchrecommendation?

A. Deceleration of the antibioticabsorptionB. Increase in the antibiotic toxicityC. Increased risk of dysbiosisD. Disruption of digestion processE. Dairy products are not digested

177. Commercial and financial acti-vity of a pharmacy involves usingreturnable tare. Which of the followi-ng containers are returned to thesupplier?

A. Metal cylindersB. Packaging materialsC. Paper boxesD. Glass-stoppered bottlesE. Glassware

178. A pharmacy has a set ofdocuments which confirm theownership of computer programs.Specify the balance sheet item thatshows the pharmacy’s property:

A. Intangible assetsB. GoodsC. Low-value equipmentD. Monetary assetsE. Stock

179. In order to expand its range ofactivities, pharmacy №12 purchasedsome manufacturing equipment.What group of economic resourcesdoes the manufacturing equipmentrelate to?

A. Fixed assetsB. GoodsC. TaraD. Tangible assetsE. Incomplete capital investments

180. A pharmaceutical analyst addedsolutions of zirconyl nitrate and ali-zarin to a drug substance. The reacti-on produced red color turning intoyellow. Specify the analyte:

A. Sodium fluorideB. Sodium chlorideC. Sodium bromideD. Sodium iodideE. Sodium thiosulfate

181. A pharmaceutical companystudies the market situation in termsof a relationship between supply anddemand, price level, stock of goods,etc. What is the company’s actualobject of study?

A. Market behaviourB. Conditions for the market existenceC. Market scopeD. Market structureE. Market infrastructure

182. During a medical briefing apharmacy intern was asked aboutthe mechanism of antiatheroscleroticeffect of clofibrate (fenofibrate).What is the correct answer?

A. It lowers triglyceridesB. It inhibits the cholesterol absorpti-onC. It binds bile acids in the smallintestineD. It has an antioxidant effectE. It inhibits the release of free fattyacids from adipose tissue

183. What style of behavior in conflictsituations involves partial satisfacti-on of the interests of both parties bymutual concessions with due consi-deration of all pros and cons?

A. CompromiseB. CooperationC. DominanceD. CompetitionE. Evasion

184. A pharmacy received aformulation for an extemporaneouslycompounded dosage form. Theformula includes phenobarbitalcompounded with other drugs. Speci-fy the required prescription form:

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A. Form № 1 in duplicateB. Form № 1C. Form № 2 in duplicateD. Form № 3E. Form № 2

185. A pharmacy has purchased arefrigerator and computer. Thesefixed assets are placed on thepharmacy’s balance sheet at thefollowing value:

A. HistoricB. AmortizedC. ResidualD. MarketE. Liquidating

186. Galenic preparations areproduced with the use of variousextractants. What extractants requirepressure as a prior condition for theextraction process?

A. Liquefied gasesB. EthanolC. Methyl alcohol, acetoneD. Vegetable oilsE. Dichloroethane, chloroform

187. In the production of dry extractsthe drying of purified extracts may notinvolve condensation of the the liquidextractions. What equipment shouldbe used in this case?

A. Spray drierB. Shelf drierC. Vacuum ovenD. ThermostatE. Rotary one-flow drier

188. Buckthorn bark is used asa laxative. Specify the period forprocurement of raw material of alderbuckthorn bark:

A. Spring, during the circulation of sapB. The period of full ripenessC. WinterD. FrondescenceE. Autumn

189. A pharmacy received a prescri-ption for phenobarbital tablets wri-tten out by a physician of the city cli-nic to an epileptic patient. Prescripti-

ons for this drug must be written outon the following prescription form:

A. Form № 3 and № 1 in a single copyB. Form № 1 in duplicateC. Form № 3 in duplicateD. Form № 1 in a single copyE. Form № 2

190. A pharmaceutical analyst hasto test the substance of iron sulfateheptahydrate for purity. What reagentshould be used to detect zinc cation inthe substance?

A. Potassium ferrocyanideB. Silver nitrateC. Barium chlorideD. Ammonium oxalateE. Sodium tetraphenylborate

191. A pharmaceutical analystperforms the identification ofphthalylsulphathiazole (phthalazol).In compliance with the SPhU requi-rements, the substance is to be heatedwith resorcinol in the presence ofsulfuric acid. The subsequent additionof sodium hydroxide and water resultsin:

A. Intensive green fluorescenceB. Abundant white precipitateC. Red-violet colorD. Extensive yellow precipitateE. Intensive blue color

192. Under the SPhU, presenceof ammonium salts in sodiumtetraborate can be detected bymethod A by using a solution of thefollowing substance:

A. Alkaline potassium tetrai-odomercurateB. Sodium tetraphenylborateC. Barium chlorideD. Potassium ferrocyanideE. Silver nitrate

193. A pharmaceutical analystperforms the identification test oflidocaine hydrochloride under theSPhU. The identity is determined bythe melting point of precipitate whichis produced as a result of reaction wi-th a solution of the following acid:

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A. PicricB. AceticC. ThioglycolicD. CitricE. Phosphoric

194. A pharmaceutist with 10 years ofservice legth is on a sick leave due totemporary disability. What allowanceis he entitled to?

A. 100% of the average wageB. 80% of the average wageC. 40% of the average wageD. 70% of the average wageE. 60% of the average wage

195. Pharmacy cashier is responsi-ble for recording all credit and debittransactions. To enter into the booksthe cash received, a cashier shouldissue:

A. Cash receipt voucherB. Cash payment voucherC. Goods receipt noteD. Goods delivery noteE. Receipt note

196. Organizational form of busi-ness in which a company does notproduce goods or services itself butowns other companies’ controllingstake and thereby supervises theiractivity is called:

A. HoldingB. ConglomerateC. SyndicateD. CartelE. Trust

197. The head of a wholesalepharmaceutical company applies

modern theories in order to effecti-vely motivate sales staff and determi-ne the amount of remuneration.Specify one of the groups of motivati-on theories:

A. ProcessB. StructuralC. PrimaryD. SecondaryE. System

198. Which of these drugs kept in thepharmacy stock relates to the groupof laxatives?

A. BisacodylB. HeparinC. VicasolD. AtropineE. Morphine

199. A pharmacy received a batch ofchemotherapeutic agents. Select anantiviral drug:

A. AcyclovirB. Benzylpenicillin sodium saltC. RifampicinD. IsoniazidE. Doxycycline

200. A 40-year-old patient has ahistory of bronchial asthma andheart rhythm disorders in form ofbradyarrhythmia. Bronchospasm canbe eliminated by the drugs of thefollowing pharmacological group:

A. M -cholinergic antagonistsB. β-blockersC. M -cholinomimeticsD. Cholinesterase inhibitorsE. Muscle relaxants